Coronary provide quantitative quantitative risk. Medical search. Frequent questions

Impaired vasodilator function is an early manifestation of coronary artery disease and may precede angiographic stenosis. (qxmd.com)
The risk of future culprit lesions was adjusted for diameter stenosis, number of adverse plaque characteristics, and quantitative plaque characteristics. (medpagetoday.com)
Cardiologists cannot solely rely on the angiographic appearance of epicardial coronary artery stenosis when evaluating patients with myocardial ischaemia. (rcpe.ac.uk)
Pressure-sensitive guidewires may be inserted through a coronary stenosis and ratio of distal coronary pressure (Pd) divided by the aortic pressure (Pa) calculated during hyperaemia. (rcpe.ac.uk)
CTA with maximum intensity projection (MIP) and quantitative measurement of stenosis is an accurate noninvasive technique for diagnosing fibromuscular dysplasia/stenosis of the visceral arteries, regardless of the etiology. (medscape.com)
AI-QCA showed a moderate to strong correlation compared with IVUS in analyzing coronary lesions with significant stenosis. (jmir.org)
Atherosclerosis imaging has been traditionally based on the evaluation of coronary luminal narrowing and stenosis. (encyclopedia.pub)
Myocardial FFR has been used as an index of functional severity of coronary artery stenosis. (medscape.com)
FFR represents the fraction of the normal maximal coronary flow that can be achieved in an artery in which flow is restricted by a coronary stenosis. (medscape.com)
FAVOR III China was designed statistically for superiority and enrolled 3847 patients with stable or unstable angina or a myocardial infarction (MI) at least 72 hours before screening if they had at least one coronary lesion with a diameter stenosis of 50% to 90% and a reference vessel diameter of at least 2.5 mm. (medscape.com)

Stress CMR yielded a DOR of 26.4 (95% CI, 10.6-65.9), a sensitivity of 81% (95% CI, 68%-89%), a specificity of 86% (95% CI, 75%-93%), and an AUROC of 0.84 (95% CI, 0.77-0.89) for the detection of functionally obstructive coronary artery disease. (lu.se)
The study of changes in disease rates after smoking cessation, compared with continuing smokers, continue to provide key information for disease control in a world where tobacco smoking constitutes the major single preventable cause of morbidity and mortality. (aacrjournals.org)
Objective We undertook a systematic review and meta-analysis to investigate the association between loneliness or social isolation and incident coronary heart disease (CHD) and stroke. (bmj.com)
2 Yet, compared with our understanding of these risk factors, we know much less about the implications of loneliness and social isolation for disease aetiology. (bmj.com)
Long-term, the findings of this study will inform a large clinical trial that can test whether sedentary behavior reduction can decrease cardiovascular disease risk. (nih.gov)
At the American Society of Human Genetics annual meeting in Los Angeles last week, they presented an evaluation of the new risk scores, which are publicly available, using a benchmarking software tool that enables like-for-like performance evaluations of PRSs for the same disease or trait. (genomeweb.com)
While PRS-based mortality predictions between parents and offspring were generally highly correlated, stroke and coronary artery disease comprised two notable outliers wherein PRS appeared to play a much greater role in predicting parents' mortality than that of their children. (genomeweb.com)
The global increase in heart disease can be attributed to risk factors and comorbidities such as diabetes, hypertension, obesity, and tobacco use. (marketresearch.com)
It is unknown whether noninvasive assessment of coronary vasodilator function in patients with suspected or known coronary artery disease carries incremental prognostic significance. (qxmd.com)
Noninvasive quantitative assessment of coronary vasodilator function with positron emission tomography is a powerful, independent predictor of cardiac mortality in patients with known or suspected coronary artery disease and provides meaningful incremental risk stratification over clinical and gated myocardial perfusion imaging variables. (qxmd.com)
Trans fat has been linked to elevated blood cholesterol and triglycerides, increasing the risk of heart disease and certain cancers. (preparedfoods.com)
Imparting truthful, factual, non-controversial information about the presence or absence and amount of trans fat in food products on the label will provide consumers with information to help them reduce their risk of coronary heart disease," notes the Final Rule on Trans Fat Declaration FDA, HHS, which will be made effective January 1, 2006. (preparedfoods.com)
Based on study findings, the authors concluded without stents, and coronary artery bypass that CPhT involvement can improve disease graft surgery. (cdc.gov)
Given the crucial role of miRNAs in gene expression, genetic variation within miRNA genes is expected to affect miRNA function and substantially contribute to disease risk. (northwestern.edu)
Methods 2,320 variants in miRNA-encoding sequences were systematically retrieved, and their associations with 17 cardiometabolic traits/diseases were investigated, using genome-wide association studies (GWAS) on glycemic indices, anthropometric measures, lipid traits, blood pressure, coronary artery disease, and type 2 diabetes. (northwestern.edu)
Cardiac markers are used for the diagnosis and risk stratification of patients with chest pain and suspected acute coronary syndrome (ACS) and for management and prognosis in patients with acute heart failure, pulmonary embolism, and other disease states. (medscape.com)
2 The risk of severe bronchospasm even amongst patients with established airways disease appears to be exceedingly rare, although the true incidence in contemporary daily cardiology practice is not known. (rcpe.ac.uk)
Reducing the incidence and prevalence of standard modifiable cardiovascular risk factors (SMuRFs) is critical to tackling the global burden of coronary artery disease (CAD). (bvsalud.org)
Risk-factor-based scoring systems for atherosclerotic coronary artery disease (CAD) remain concerningly inaccurate at the level of the individual and would benefit from the addition of biomarkers that correlate with atherosclerosis burden directly. (bvsalud.org)
We hypothesized that serum soluble lectin-like oxidized low-density lipoprotein receptor-1 (sLOX-1) would be independently associated with CAD and investigated this in the BioHEART study using 968 participants with CT coronary angiograms, which were scored for disease burden in the form of coronary artery calcium scores (CACS), Gensini scores, and a semi-quantitative soft-plaque score (SPS). (bvsalud.org)
The current coronary artery disease (CAD) risk scores for predicting future cardiovascular events rely on well-recognized traditional cardiovascular risk factors derived from a population level but often fail individuals, with up to 25% of first-time heart attack patients having no risk factors. (bvsalud.org)
A low HLD indicates increase risk in coronary heart disease, while high LDL level indicates lower risk. (asavea.com)
Smooth muscle cell (SMC) phenotypic transition, which leads to the formation of various cell types in atherosclerotic plaques, is regulated by a network of genetic and epigenetic mechanisms and governs the risk of disease. (stanford.edu)
However, SMC lncRNAs have not been comprehensively characterized, and their regulatory role in SMC state transition remains unknown.A discovery pipeline was constructed and applied to deeply strand-specific RNA sequencing from perturbed human coronary artery SMC with different disease-related stimuli, to allow for the detection of novel lncRNAs. (stanford.edu)
Atherosclerotic plaques consist mostly of smooth muscle cells (SMC), and genes that influence SMC phenotype can modulate coronary artery disease (CAD) risk. (stanford.edu)
To better understand the epigenetic and transcriptional mechanisms that mediate these cell state changes, and how they relate to risk for coronary artery disease (CAD), we have investigated the causality and function of transcription factors (TFs) at genome wide associated loci. (stanford.edu)
We assessed the prognostic value of perivascular fat attenuation mapping for all-cause and cardiac mortality in Cox regression models, adjusted for age, sex, cardiovascular risk factors, tube voltage, modified Duke coronary artery disease index, and number of coronary CTA-derived high-risk plaque features. (ox.ac.uk)
His major scientific contributions included: 1) Development of an automated atlas of the human cerebral cortex (Desikan-Killiany Atlas in FreeSurfer), and its role as a quantitative biomarker for neurodegeneration in Alzheimer's disease. (wikipedia.org)
These genetic pleiotropy methods have provided valuable insights across a number of diseases and identified Novel Single Nucleotide Polymorphisms (SNPs) associated with increased risk for schizophrenia, bipolar disorder, Alzheimer's disease, Parkinson's disease, frontotemporal dementia, corticobasal degeneration, hypertension, hypercholesterolemia and coronary artery disease. (wikipedia.org)
HDL and cardiovascular-disease risk-time for a new approach? (skanestugan.se)
endobj The high concentration of low-density lipoprotein cholesterol (LDL-c) is an independent risk factor for coronary artery disease. (skanestugan.se)
Recent research has shown that regular consumption of omega-3s can help reduce your risk of heart disease. (supplementsreport.com)
A recent meta-analysis featuring over 900,000 participants provides strong evidence of the connection between omega-3 intake and the prevention of heart disease . (supplementsreport.com)
Study leader Dr. Dominik D. Alexander, Principal Epidemiologist at the EpidStat Institute in Ann Arbor, Michigan, commented on the research and stated, "To our knowledge, this is the most comprehensive quantitative assessment of the relationship between EPA+DHA supplementation and intake and coronary heart disease risk to date. (supplementsreport.com)
In the randomized trials, a six-percent overall reduction in any coronary heart disease event was observed. (supplementsreport.com)
The scientists define a coronary heart disease event as "fatal or nonfatal heart attack, sudden cardiac death and angina. (supplementsreport.com)
For example, participants with high triglyceride levels who took the EPA and DHA supplement saw a 16-percent drop in heart disease risk compared to those who didn't take the supplement. (supplementsreport.com)
In the prospective cohort studies, an 18-percent reduction in heart disease risk was associated with participants with a high intake of EPA and DHA. (supplementsreport.com)
However, they are also important for summarising other evidence, such as the accuracy of screening and diagnostic tests, 1 the causal association of risk factors for disease onset, and the prognostic ability of bespoke factors and biomarkers. (bmj.com)
A majority of them may have pre-existing risk factors for cardiovascular disease, which is the primary cause of non-cancer death among people with prostate cancer. (biospace.com)
The goal of this project is to improve the awareness, identification, and implementation of interventions for known modifiable risk factors (i.e. hypertension, dyslipidemia, diabetes) for cardiovascular disease. (biospace.com)
All patients admitted consecutively between 2009 and 2010 for ACS were included in the RENACI database of the Working Group on Ischemic Heart Disease and Coronary Care Units of the Spanish Cardiology Society. (hindawi.com)
Risk factors for FMD include gender, age, and history of smoking, with the disease primarily affecting middle-aged women. (medscape.com)
Menopause is associated with dyslipidemia and an increased risk of cardio-cerebrovascular disease. (nature.com)
1 During menopause, the prevalence of dyslipidemia also increases, which is the major risk factor of cardio-cerebrovascular disease. (nature.com)
The Cholesterol Complete Test is used to screen for elevated cholesterol as a risk factor in coronary artery disease. (newhealthcorp.com)
It is a good idea to understand how your heart is working, as coronary artery disease is the leading cause of death worldwide, accounting for over 7 million deaths each year, more than any other disease. (healmindbody.com)
The MCG is a revolution in medicine as it offers an easy and inexpensive method to detect coronary artery disease and other forms of heart dysfunction. (healmindbody.com)
The risk factors for heart disease progress slowly and silently, day after day. (healmindbody.com)
Now you can easily assess the health of your heart and take lifestyle and mind style steps in prevent and reverse coronary artery disease, using the MCG to monitor your progress. (healmindbody.com)
Identifying patients at increased risk of coronary artery disease, before the atherosclerotic complications become clinically evident, is the aim of cardiovascular prevention. (encyclopedia.pub)
Imaging techniques provide direct assessment of coronary atherosclerotic burden and pathological characteristics of atherosclerotic lesions which may predict the progression of disease. (encyclopedia.pub)
Atherosclerosis is the primary cause of coronary artery disease (CAD) [ 1 ] [ 2 ] . (encyclopedia.pub)
Statins are widely used and well tolerated cholesterol-lowering drugs, and when used for therapy purposes reduce morbidity and mortality from coronary heart disease. (degruyter.com)
Statin drugs represent the major improvement in the treatment of hypercholesterolemia that constitutes the main origin of atherosclerosis, leading to coronary heart disease. (degruyter.com)
3. Exposure of adults to secondhand smoke has immediate adverse effects on the cardiovascular system and causes coronary heart disease and lung cancer. (nosmoke55.jp)
Background: Patients with COPD have an independent increased risk of cardiovascular (CV) disease. (bjgpopen.org)
Our objective was to examine the pattern of lifestyle factors associated with cardiovascular disease (CVD) in Grenada and to determine whether the prevalence of CVD risk factors differs by subgroups. (cdc.gov)
concurrently, these countries' populations often experience changes in diet and reductions in physical activity that lead to higher prevalence of cardiovascular disease (CVD) and CVD risk factors (3). (cdc.gov)
Obesity not only adversely affects metabolism, but also increases the risk of developing adult diseases such as coronary artery disease, high blood pressure, and diabetes. (accuniq.com)
As the burden of chronic diseases in the United States continues to increase, greater efforts are being made to identify and implement interventions that successfully reduce disease risk, improve access to high-quality health care, and create sustainable health-promotion programs that ultimately improve health status and quality of life ( 1 ). (cdc.gov)
Safety of treatment, changes in risk factors, and incidence of coronary heart disease. (emeco.es)
New guidelines on screening for cardiovascular risk, released in late 2013 by the American Heart Association/American College of Cardiology (AHA/ACC), recommend use of a revised calculator for estimating the 10-year risk of developing a first atherosclerotic CVD event, which is defined as nonfatal myocardial infarction, death from coronary heart disease, or stroke (fatal or nonfatal) in a person who was initially free from atherosclerotic CVD. (medscape.com)
Criteria are required to help identify the most critical risks to health, which might include the potential global impact, covering all major causes of death and disability (likely to be among the leading causes of disease burden), strength and consistency of scientific evidence, and the potential for modification. (who.int)
Unsafe sex was the next highest risk, with much of this disease burden concentrated in the African Region. (who.int)
Risk assessment estimates the burden of disease due to different risk factors, each of which may be altered by many different strategies. (who.int)
Taking vitamin B6 supplements by mouth or eating large amounts of vitamin B6 in the diet doesn't seem to reduce the risk for Alzheimer disease. (medlineplus.gov)
Overview of Coronary Artery Disease Coronary artery disease (CAD) involves impairment of blood flow through the coronary arteries, most commonly by atheromas. (msdmanuals.com)

However, a substantial number of individuals develop coronary atherosclerosis despite no SMuRFs. (bvsalud.org)
Coronary Atherosclerosis Imaging" Encyclopedia , https://encyclopedia.pub/entry/12034 (accessed December 06, 2023). (encyclopedia.pub)

Furthermore, trans- expression quantitative trait loci analysis and luciferase reporter assay to provide functional evidence for our findings were performed. (northwestern.edu)

This study aims to describe the outcome of intravascular lithotripsy (IVL) when used with different indications and to assess the short- and long-term outcomes of IVL-facilitated percutaneous coronary intervention (PCI). (frontiersin.org)
Up to 30% of patients undergoing percutaneous coronary intervention (PCI) have calcified lesions ( 1 ). (frontiersin.org)
Objectives Percutaneous coronary intervention (PCI) for acute coronary syndromes frequently fails to restore myocardial perfusion despite establishing epicardial vessel patency. (bmj.com)
Following percutaneous coronary intervention (PCI) for acute coronary syndromes, rise in endothelin-1 (ET-1) levels, a potent vasoconstrictor produced by the vascular endothelium, has been proposed as a potential mediator of reperfusion injury and 'no reflow' phenomenon. (bmj.com)
Percutaneous coronary intervention (PCI) guided by quantitative flow ratio (QFR) lesion assessment provided better clinical outcomes than visual assessment of the angiogram in the sham-controlled FAVOR III China study. (medscape.com)

The CardioChek HDL Test Strip provides a quantitative measurement of high density lipoprotein (HDL) cholesterol in whole blood. (asavea.com)
The Cholesterol Complete Test is intended for in-vitro diagnostic for the semi-quantitative determination of Cholesterol and High-Density Lipoprotein (HDL) in whole blood. (newhealthcorp.com)
Background: Epidemiological studies have repeatedly confirmed low plasma levels of High Density Lipoprotein (HDL) as an independent risk factor for arteriosclerotic diseases. (fu-berlin.de)

A recent study characterized the prognostic value of adverse geometric characteristics of coronary lesions in predicting future acute coronary syndrome events. (medpagetoday.com)
We sought to characterize AGCs of coronary lesions capturing location and vessel geometry on baseline CCTA. (medpagetoday.com)
The authors hypothesized that beyond current qualitative and quantitative plaque features associated with risk of future ACS, AGCs, including lesion location and vessel geometry, are independently associated with future ACS-causing culprit lesions. (medpagetoday.com)
3 In patients with ACS and 2 or more significant lesions, the culprit lesion was defined using invasive coronary angiography and electrocardiography. (medpagetoday.com)
All coronary lesions were qualitatively evaluated for adverse morphological features, including positive remodeling, low attenuation, spotty calcification, and napkin-ring sign. (medpagetoday.com)
Additionally, coronary lesions were identified for 3 AGCs: distance from ostium to lesion, location at vessel bifurcation, and vessel tortuosity, which was defined as the presence of 1 bend of greater than 90 degrees or 3 curves of 45 to 90 degrees. (medpagetoday.com)
Intravascular lithotripsy can improve the results of PCI of calcified coronary lesions with a low rate of periprocedural complications. (frontiersin.org)
Treatment of calcified coronary lesions with IVL in a "real-world" setting can be performed with high success, low rate of procedural complications, and an acceptable MACEs rate. (frontiersin.org)
Several technological developments have been introduced to aid in the treatment of severely calcified coronary lesions. (frontiersin.org)
The aim of this study was to evaluate the outcome of IVL-facilitated PCI in an all-comers population with calcified coronary lesions, focusing on the short- and long-term results related to different uses of IVL in the "real-world" practice. (frontiersin.org)
This retrospective, observational study included consecutive patients with calcified coronary lesions treated with IVL from December 31, 2018 to December 31, 2020 at the Centro Cardiologico Monzino, University of Milan, Italy. (frontiersin.org)
An accurate quantitative analysis of coronary artery stenotic lesions is essential to make optimal clinical decisions. (jmir.org)
Non-invasive visualization of the morphology of coronary atherosclerotic lesions is performed using computed tomography (CT), computed tomography coronary angiography (CTCA), and cardiac magnetic resonance (CMR). (encyclopedia.pub)
This suggests that although measurements of coronary flow reserve (CFR) and fractional flow reserve (FFR), both of which are discussed below, may be useful in the assessment of the severity of stenoses and in the identification of lesions responsible for effort angina, they are not likely to identify the more dangerous plaques responsible for unstable angina, AMI, and sudden ischemic death. (medscape.com)
Our data indicate that the utility of risk-based screening for mpox in persons without skin lesions or rash via pharyngeal swabs, rectal swabs, and/or blood is likely limited. (cdc.gov)

Intake of seven individual whole grain foods was repeatedly assessed using a validated semi-quantitative food frequency questionnaire every 2-4 years since baseline. (harvard.edu)
Falk Delgado A, Nilsson M, Latini L, Mårtensson J, Zetterling M, Ghaderi Berntsson S, Alafuzoff I, Lätt J, Larsson E-M. Preoperative semi-quantitative MR tractography compared with visual tract evaluation and neuropathological diagnosis in patients with suspected low-grade glioma: A prospective cohort study. (lu.se)

Perivascular fat attenuation mapping was done around the three major coronary arteries-the proximal right coronary artery, the left anterior descending artery, and the left circumflex artery. (ox.ac.uk)
MRA provides accurate information about the number of renal arteries, the size of the kidneys, and the presence of anatomic variants. (medscape.com)
The gold standard for coronary artery evaluation is the Coronary Angiogram, which requires hospitalization and a catheter inserted in an artery and guided to the heart where it can release dye which is seen in the heart arteries. (healmindbody.com)
The standard method for CAC quantification is the Agatston score which measures the density of calcification in each coronary segment, multiplied by the area and summed for all arteries [ 5 ] . (encyclopedia.pub)

Objective Risk Assessment vs Standard Care for Acute Coronary Syndromes: A Randomized Clinical Trial. (thecvc.ca)
In this study, we aim to define the role of endothelin in regulating coronary microvascular blood flow and myocardial perfusion following PCI in patients with non-ST elevation acute coronary syndromes (NSTACS), by assessing whether adjunctive therapy with a selective endothelin A (ET A ) receptor antagonist acutely improves postprocedural coronary microvascular blood flow. (bmj.com)

Improved cardiac risk assessment with noninvasive measures of coronary flow reserve. (qxmd.com)
Corresponding improvements in risk assessment for mortality from any cause were also demonstrated. (qxmd.com)
INTERPRETATION: The perivascular FAI enhances cardiac risk prediction and restratification over and above current state-of-the-art assessment in coronary CTA by providing a quantitative measure of coronary inflammation. (ox.ac.uk)
The aim of performing imaging diagnostic tests is the assessment of patients at risk of acute coronary events associated with plaque formation, before atherosclerotic complications occur. (encyclopedia.pub)
In high-risk patients, intravascular imaging provides accurate assessment of vulnerable plaques and early stage of their development. (encyclopedia.pub)
Non-contrast electrocardiographic (ECG)-gated multidetector CT provides a direct quantitative assessment of coronary artery calcium (CAC) [ 4 ] . (encyclopedia.pub)
Each chapter provides a comprehensive review of the evidence, a quantitative synthesis of the evidence if appropriate, and a rigorous assessment of sources of bias that may affect interpretations of the findings. (nosmoke55.jp)
CV-risk (CVR) assessment should be offered to all COPD-patients according to the new Dutch 'CVR management' (CVRM) guideline (May-2019). (bjgpopen.org)
Data from 2014-2019 were used for the qualitative risk assessment based on comorbidities, and the quantitative Systematic Coronary Risk Assessment (SCORE). (bjgpopen.org)
Results: Of the 391 COPD-patients, 84.1% (n=329) had complete data on CVR assessment: 90.3% (n=297) had a (very)-high risk and 9.7% (n=32) a low-to-moderate risk. (bjgpopen.org)
Readdressing this imbalance is a key focus of WHO, other international organizations and governments, starting with an assessment of how much more prevalent risks are among the poor. (who.int)
The role and contribution of risk assessment, communication, risk management, cost-effectiveness, and policy development are key topics for debate. (who.int)
These estimates have been calculated in collaboration with a worldwide network of experts in risk assessment. (who.int)

Research to identify genuine prognostic factors is important because these factors can help improve risk stratification, treatment, and lifestyle decisions, and the design of randomised trials. (bmj.com)
Non-invasive imaging is best suited in primary prevention for low- intermediate- risk population, in order to improve risk stratification and identify individuals who may benefit from intensive treatment. (encyclopedia.pub)
Regarding cardiovascular risk stratification, both the intervention (26 %) and the control (6 %) groups shifted to the lower-risk class. (bvsalud.org)

sLOX-1 is associated with CAD severity and is the first biomarker shown to have utility for risk prediction in the SMuRFless population. (bvsalud.org)
A novel imaging biomarker-the perivascular fat attenuation index (FAI)-captures coronary inflammation by mapping spatial changes of perivascular fat attenuation on coronary computed tomography angiography (CTA). (ox.ac.uk)
Post-PCI coronary microvascular blood flow and myocardial perfusion were assessed by measuring Doppler-derived average peak velocity (APV), and cardiac biomarker levels were quantified. (bmj.com)

IMPORTANCE: The clinical utility of stress cardiovascular magnetic resonance imaging (CMR) in stable chest pain is still debated, and the low-risk period for adverse cardiovascular (CV) events after a negative test result is unknown. (lu.se)
In this study, quantitative characterization of plaque using coronary computed tomographic angiography (CTA) will be used to determine if women who were treated with intensive medical therapy have a greater reduction in the amount and type of cholesterol plaque compared to women receiving usual care and if this results in beneficial changes in clinical symptoms. (nih.gov)
The study will provide an understanding of how intensive medical therapy works in providing clinical benefit in women with nonobstructive plaque. (nih.gov)
The study was Kaiser ambulatory care clinics have been utilized to Permanente Colorado's clinical pharmacy expand access to care, close gaps in treatment cardiac risk reduction service (CPCRS). (cdc.gov)
Prognostic factors are associated with the risk of future health outcomes in individuals with a particular health condition or some clinical start point (eg, a particular diagnosis). (bmj.com)
Clinical and anthropometric variables were analyzed in patients consecutively admitted for acute coronary syndrome to a university hospital between 2009 and 2010, and the correlation of those variables with hospital mortality was examined. (hindawi.com)
The results from MCG have been validated in double-blind clinical studies where the system has demonstrated accuracy comparable to coronary angiography (90% overall sensitivity, 85% specificity). (healmindbody.com)
This level of accuracy comes from the application of advanced techniques in signal processing and systems analysis combined with a large scale clinical database which allows MCG to provide quantitative, evidence-based results to assist physicians in reaching a diagnosis. (healmindbody.com)
We believe that this novel tool could provide confidence to treating physicians and help in making optimal clinical decisions. (jmir.org)
[ 24 ] The calculator uses a combination of clinical and laboratory risk factors to estimate risk. (medscape.com)
For patients 20-79 years of age who do not have existing clinical atherosclerotic CVD, the guidelines recommend assessing clinical risk factors every 4-6 years. (medscape.com)

Methods Using an electronic patient database, we analysed 100,253 consecutive coronary angiograms over almost 19 years. (rcpe.ac.uk)
A recent near life-threatening respiratory arrest during intravenous adenosine administration for FFR at our centre prompted a systematic review of over 100,000 invasive coronary angiograms performed over almost two decades. (rcpe.ac.uk)
Using an electronic patient database, we analysed 100,253 consecutive coronary angiograms performed at the Glasgow Royal Infirmary, Western Infirmary Glasgow, Stobhill Hospital and the Golden Jubilee National Hospital over almost 19 years between January 2000 and November 2018. (rcpe.ac.uk)
MRA produces excellent contrast-enhanced angiograms without the risk of iodinated compounds and radiation exposure. (medscape.com)

The predictive value of sLOX-1 was significantly greater in the subgroup of patients who did not have any of the standard modifiable cardiovascular risk factors (SMuRFs). (bvsalud.org)
In addition to being a crucial underlying circumstance in the primary cardiovascular risk factors (CVRFs), obesity is an independent risk factor for cardiovascular illness and mortality [ 1 , 2 ]. (hindawi.com)

The functional relevance of a select few novel lncRNAs were verified in vitro.We identified 4579 known and 13 655 de novo lncRNAs in human coronary artery SMC. (stanford.edu)
Combining transcriptional data and in silico modeling along with in vitro validation, we identified CAD gene ZEB2 as a target through which these lncRNAs exert their function in SMC phenotypic transition.Expression of a large and diverse set of lncRNAs in human coronary artery SMC are highly dynamic in response to CAD-related stimuli. (stanford.edu)

Short-term NSAID use might increase heart failure risks among people with type 2 diabetes (T2D). (cardiacwire.com)
2 They explored systematically the existing data sources currently used in the UK to monitor and evaluate coronary heart diseases (CHD) and related aspects of prevention and care. (bmj.com)
Federation sponsored the Grenada Heart Project (GHP) to examine effects of the epidemiologic transition on CVD risk in the nation (2). (cdc.gov)
Because myocardial oxygen demand is determined mainly by heart rate, systolic wall tension, and contractility, narrowing of a coronary artery typically results in angina that occurs during exertion and is relieved by rest. (msdmanuals.com)

With the multistage-screening approach, patients deemed high risk would be treated with statins, those deemed low risk would be monitored without treatment, and intermediate-risk patients would undergo laboratory testing of cholesterol levels. (medscape.com)

Background Adenosine is frequently used during coronary angiography to induce hyperaemia and allow operators to perform quantitative measurements of lesion severity. (rcpe.ac.uk)
The emerging field of coronary physiology allows operators to perform quantitative measurements of lesion severity and are evidence based to guide the need for coronary intervention. (rcpe.ac.uk)

While inducible myocardial ischemia and LGE were associated with higher mortality and risk of MACEs, normal stress CMR results were associated with a lower risk of MACEs for at least 3.5 years. (lu.se)
The report reveals local or widespread coronary artery blockage and ischemia in mild, moderate or severe gradations. (healmindbody.com)

This dedicated pathway for a previously overlooked CAD population, with an accompanying registry, aims to improve outcomes through enhanced adherence to evidence-based secondary prevention and additional diagnosis of modifiable risk factors observed. (bvsalud.org)
Other factors which determine whether policies are adopted include public perceptions of the risks and benefits involved, the extent to which risks are distributed, and the degree of inequality as to outcomes. (who.int)

Increased body mass index (BMI) alters the behavior of adipose tissue, which provides insulin resistance as well as resistance to type-2 diabetes, arterial hypertension, dyslipidemia, and proinflammatory and prothrombotic states, thereby favoring the onset of ischemic cardiopathy [ 3 ]. (hindawi.com)
As the myocardium becomes ischemic, coronary sinus blood pH falls, cellular potassium is lost, lactate accumulates, ECG abnormalities appear, and ventricular function (both systolic and diastolic) deteriorates. (msdmanuals.com)

The model illustrates qualitative and quantitative trends within the specified market. (marketresearch.com)
Successfully tackling risks to health involves many stakeholders from different sections of society, a combination of scientific and political processes, many qualitative and quantitative judgements, and opportunities for open communication and dialogue. (who.int)

This multicenter, nested case-control study was a substudy of ICONIC (Incident Coronary Syndromes Identified by Computed Tomography) and included patients who had ACS with a culprit lesion precursor seen on CCTA. (medpagetoday.com)

The aim of this paper is to validate the performance of artificial intelligence-based quantitative coronary angiography (AI-QCA) in comparison with that of intravascular ultrasound (IVUS). (jmir.org)
Intravascular ultrasound (IVUS) offers detailed 3D tomographic views of coronary plaques and reference vessels. (jmir.org)

Coronary Stents (Cardiovascular) - Global Market Analysis and Forecast Model (COVID-19 Market Impact) is built to visualize quantitative market trends within Cardiovascular Devices therapeutic area. (marketresearch.com)
The model discusses in detail the impact of COVID-19 on Coronary Stents market for the year 2020 and beyond. (marketresearch.com)
The Coronary Stents Market is segmented into Bare Metal Stents, Drug Eluting Stents (DES), Covered Stents, Bioabsorbable Stents (BAS). (marketresearch.com)
Annualized total Coronary Stents market revenue by segment and market outlooks from 2015-2030. (marketresearch.com)
SWOT analysis for Coronary Stents market. (marketresearch.com)
Competitive dynamics insights and trends provided Coronary Stents market. (marketresearch.com)
CMO executives who must have deep understanding of the Coronary stents marketplace to make strategic planning and investment decisions. (marketresearch.com)

Non-invasive detection of coronary inflammation using computed tomography and prediction of residual cardiovascular risk (the CRISP CT study): a post-hoc analysis of prospective outcome data. (ox.ac.uk)
METHODS: In the Cardiovascular RISk Prediction using Computed Tomography (CRISP-CT) study, we did a post-hoc analysis of outcome data gathered prospectively from two independent cohorts of consecutive patients undergoing coronary CTA in Erlangen, Germany (derivation cohort) and Cleveland, OH, USA (validation cohort). (ox.ac.uk)

Reports of 11 CHD studies and 8 stroke studies provided data suitable for meta-analysis. (bmj.com)
Poor social relationships were associated with a 29% increase in risk of incident CHD (pooled relative risk: 1.29, 95% CI 1.04 to 1.59) and a 32% increase in risk of stroke (pooled relative risk: 1.32, 95% CI 1.04 to 1.68). (bmj.com)
Conclusions Our findings suggest that deficiencies in social relationships are associated with an increased risk of developing CHD and stroke. (bmj.com)

In patients with acute coronary syndrome (ACS), coronary computed tomographic angiography (CCTA) was used to capture adverse geometric characteristics (AGCs) of coronary plaques. (medpagetoday.com)
Smooth muscle cells (SMCs), the major cell type in atherosclerotic plaques, are vital in coronary artery diseases (CADs). (stanford.edu)
More recent techniques focus on the high-resolution visualization of the arterial wall and the coronary plaques. (encyclopedia.pub)
This objective is based on the identification of coronary atherosclerotic burden, its extent and pathological characteristics which are closely associated with progression and rupture of vulnerable plaques. (encyclopedia.pub)
Extensive calcification is associated with higher risk of CAD, because the presence of more plaques increases the chance that one may rupture. (encyclopedia.pub)

The quantitative burden of noncalcified plaque volume from CCTA was also evaluated. (medpagetoday.com)
Non-invasive imaging technology can directly measure coronary artery plaque burden. (bvsalud.org)
Lipid features have strong potential as biomarkers to predict CAD plaque burden and can identify residual risk not captured by traditional risk factors/scores. (bvsalud.org)
Most acute coronary events are triggered by plaque rupture or erosion. (encyclopedia.pub)
However, most acute coronary events occur from atherosclerotic plaque rupture or erosion causing arterial thrombosis [ 3 ] . (encyclopedia.pub)

They also note that experiences to date suggest that up to 20% of patients may be unsuitable for the algorithm analysis because of coronary anatomy, presence of overlapping vessels, and insufficient image quality. (medscape.com)

LOS ANGELES - Researchers at Genomics PLC have developed a new set of polygenic risk scores for 53 diseases and traits using data from the UK Biobank. (genomeweb.com)
The new PRSs, detailed in a preprint published in MedRxiv in August, cover 28 diseases and 25 quantitative traits, split between a Standard PRS Set consisting of 28 diseases and eight quantitative traits and an Enhanced PRS Set containing all new PRSs. (genomeweb.com)
Using 'big data' acquired through ongoing global collaborations, he innovated a variety of cross disciplinary methods to identify novel risk factors for brain diseases. (wikipedia.org)
With a standardised tool, the authors review the sources related to persons and to treatments, as well as data sources on classic risk factors for cardiovascular diseases. (bmj.com)
Following a request from five European Nordic countries, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was tasked to provide scientific advice on a tolerable upper intake level (UL) or a safe level of intake for dietary (total/added/free) sugars based on available data on chronic metabolic diseases, pregnancy-related endpoints and dental caries. (lih.lu)
A level of sugars intake at which the risk of dental caries/chronic metabolic diseases is not increased could not be identified over the range of observed intakes, and thus, a UL or a safe level of intake could not be set. (lih.lu)

OBJECTIVE: To provide contemporary quantitative data synthesis of the diagnostic accuracy and prognostic value of stress CMR in stable chest pain. (lu.se)

Cardiopulmonary bypass during cardiac surgery provides blood flow to the body during surgery but has adverse effects on different organs. (nih.gov)

This retrospective study included patients who underwent IVUS-guided coronary intervention at a single tertiary center in Korea. (jmir.org)

If performed well, it provides diagnostic quality images in patients with implantable cardiac devices or severe renal dysfunction, and also allows whole body imaging which can help identify foci of extra-cardiac sarcoidosis. (asnc.org)

1 The influence of social relationships on mortality is comparable with well-established risk factors, including physical activity and obesity. (bmj.com)
Although obesity is a well-established cardiovascular risk factor, some controversy has arisen with regard to its effect on hospital mortality in patients admitted for acute coronary syndrome. (hindawi.com)
It would therefore be logical to expect obesity to have a lethal effect on patients who have suffered a coronary event. (hindawi.com)
This situation, in which obesity seems to protect patients with acute coronary syndrome (ACS), has been called "the obesity paradox" and has been described in other facilities. (hindawi.com)
In addition to simple body composition results, it provides various information such as sarcopenia, cell health, obesity evaluation, control guide, and body type determination. (accuniq.com)
ACCUNIQ body composition analyzer increases the utilization of obesity management through quantitative analysis of fat and skeletal muscle in terms of body weight by measuring weight, skeletal muscle, and body fat, and individualized standard ranges. (accuniq.com)
For patients with elevated 10-year risk, clinicians should communicate risk data and refer to the AHA/ACC guidelines on blood cholesterol and obesity. (medscape.com)

During the past decades the field of risk analysis has grown rapidly, focusing on identification, quantification, and characterization of threats to human health and the environment. (who.int)

Adults who have few social contacts (ie, who are socially isolated) or feel unhappy about their social relationships (ie, who are lonely) are at increased risk of premature mortality. (bmj.com)
In both cohorts, high perivascular FAI values around the proximal right coronary artery and left anterior descending artery (but not around the left circumflex artery) were predictive of all-cause and cardiac mortality and correlated strongly with each other. (ox.ac.uk)
Perivascular FAI improved risk discrimination in both cohorts, leading to significant reclassification for all-cause and cardiac mortality. (ox.ac.uk)
There is something of a paradox in the relationship between body mass index and hospital mortality in patients with acute coronary syndrome in that the mortality rate decreases as body mass index increases. (hindawi.com)
A JAMA study of nearly 20k patients suggests that early detection and treatment of cardiac implantable electronic device (CIED) infections significantly reduces mortality risks . (cardiacwire.com)
The researchers found that early localized CIED infections did not raise mortality risks, but early systemic infections and delayed localized infections increased mortality risks three-fold, with delayed systemic infections posing the highest risk. (cardiacwire.com)
Physical activity before and after the menopause may have different influences on subsequent mortality, because the onset of the menopause is associated with a less favourable cardiovascular risk factor profile. (bmj.com)

Unlike contrast-enhanced angiography, MRA has no attendant risk of nephropathy caused by contrast agent or cholesterol-emboli syndrome. (medscape.com)
one (1) lancet should be able to provide enough whole blood to fill 2 blood collection droppers ("droppers") in order to complete both the Total Cholesterol and HDL tests. (newhealthcorp.com)
A screening strategy for calculating cardiovascular risk that uses multiple non-laboratory-based risk markers performed as well as approaches based on Framingham risk scores, which use cholesterol measurements in all patients. (medscape.com)
Four risk factors (high blood pressure, tobacco use, alcohol consumption, and unsafe water, sanitation, or hygiene) were ranked next, followed by high cholesterol and indoor air pollution. (who.int)

We would like to highlight that the proposed adverse geometric characteristics can be obtained in a standard workstation using simple distance and angle measurements and can provide complementary prognostic information to standard CCTA evaluation. (medpagetoday.com)
1% risk of adverse cardiac events, and no ventricular arrhythmia events in absence of LGE. (asnc.org)
A risk to health may be thought of as any factor that raises the probability of an adverse health outcome. (who.int)

Through a machine learning approach, we built a lipid risk score (LRS) and compared the performance of the existing Framingham Risk Score (FRS) in predicting sCAD+. (bvsalud.org)

Also required is a comprehensive approach to the definition and study of risks, irrespective of factors such as place in the causal chain and the disciplinary methods used for analysis. (who.int)

The 1982 publication of The Prevention and Treatment of Five Complications of Diabetes: A Guide for Primary Care Practitioners was an initial attempt to provide straightforward and practical information that primary care practitioners could immediately apply in their practice in the diagnosis and prevention of complications of diabetes. (cdc.gov)
Diabetes itself does not cause changes in personality or psychiatric illness, but particular subgroups of the diabetic population appear to be at risk for developing psychosocial problems. (cdc.gov)
Elderly persons who have non-insulin-dependent diabetes mellitus (NIDDM) and other symptomatic medical conditions may also have a higher risk of developing psychological problems. (cdc.gov)
A study by Paynter et al found that models incorporating HbA 1c levels significantly improved prediction of CVD risk among patients with diabetes. (medscape.com)

QFR, however, is derived from 3-dimensional coronary artery reconstruction and computational fluid dynamics from the angiogram, so FFR can be estimated without the need for a pressure wire or hyperemic drugs. (medscape.com)

Often, the greatest burden of health risks is borne by vulnerable groups: poor people, those with little formal education, and those with low-status occupations. (who.int)

Statin users might still risk muscle injuries with strenuous exercise, but these findings suggest that "moderate" exercise (like four straight 31-mile walks) doesn't damage statin users' muscles, while reinforcing recommendations to combine statin therapy with a physically active lifestyle. (cardiacwire.com)

The researchers propose that exercise and weight loss interventions (bariatric surgery) will restore adipose tissue homeostasis, reduce GSL-loaded adiposomes, and subsequently alleviate vascular risk in OB-T2D patients. (nih.gov)
The reduction in risk was most significant in high-risk patients. (supplementsreport.com)
Each grade represents a group of patients with a different prognosis, and the risk or rate (hazard) of the outcome increases with higher grades. (bmj.com)
The National Comprehensive Cancer Network's Oncology Research Program is collaborating with Pfizer and Myovant to address cardiovascular risk in patients with prostate cancer being treated with androgen deprivation therapy (ADT). (biospace.com)
Data also shows that roughly a third of patients with uncontrolled risk factors for cardiovascular events are not on appropriate medications. (biospace.com)
However, some studies have reported better short- and medium-term prognoses in overweight coronary patients [ 5 , 6 ]. (hindawi.com)
In 15.9% (n=62) of all COPD-patients, the CVR profile was not measured and of the (very)-high-risk patients, 26.6% (n=79) was not enrolled in a CV-care program. (bjgpopen.org)
Moreover, once a (very)-high risk has been assessed, as a consequence CV treatment of risk factors should be intensified in one out of four COPD-patients. (bjgpopen.org)
Adherence to the new CVRM guideline could provide improvement in CVRM in more than a third of all COPD-patients. (bjgpopen.org)
7.5%), the guidelines recommend assessing 30-year or lifetime risk in patients 20-59 years old. (medscape.com)

An estimated 42.3% of coronary episodes in the Spanish population may be attributable to excess weight after adjusting for age, sex, and other risk factors [ 4 ]. (hindawi.com)
These changes are clearly inappropriate when studying slow secular changes in the pattern of risk factors. (bmj.com)
We collected behavioral, anthropometric, and blood sample data to assess the prevalence of CVD risk factors. (cdc.gov)
Participants who had migrated tended to be older and have different CVD risk factors than those who had never migrated. (cdc.gov)
In the midst of an epidemiologic transition in the Caribbean nation of Grenada in which CVD risk is increasing, dietary risk factors are most prevalent among women and among all adults younger than 55. (cdc.gov)
Factors postulated to explain this phenomenon range from increased prevalence of individual risk factors ( 8 ), a lack of health care resources for the poor and underserved ( 9 ), and environmental conditions that do not support the adoption and sustainability of healthy eating and physical activity behavior ( 10 ). (cdc.gov)
Without some quantitative approach to gauging their importance, in terms of likely impact, there is greater likelihood of policy being driven exclusively by factors such as pressure groups or the emotive weight of individual cases. (who.int)
A key aim of risk analysis is therefore to improve comparability between estimates of the impact of different risk factors. (who.int)
Estimates of the leading risks to health among a selected set of risk factors are given in Annex 1. (who.int)

Potentielt kan en sådan viden omsættes til klinisk brug med mere målrettet terapi og tidligere intervention, end traditionel symptomatologi og udredning muliggør [6, 7]. (ugeskriftet.dk)

Anatomy14

Organisms3

Diseases52

Chemicals and Drugs44

Analytical, Diagnostic and Therapeutic Techniques and Equipment75

Psychiatry and Psychology1

Phenomena and Processes24

Disciplines and Occupations1

Information Science6

Health Care39

Geographicals2

Stenosis10

Disease68

Atherosclerosis2

Trait Loci1

Percutaneous5

High density lip3

Lesions15

Semi-quantitative2

Arteries4

Acute Coronary2

Assessment13

Stratification3

Biomarker3

Clinical11

Angiograms4

Cardiovascular risk factors2

Human coronary2

Heart4

Statins1

Severity2

Ischemia2

Outcomes2

Ischemic2

Qualitative and quantitative2

Lesion1

Intravascular2

Stents7

Computed Tomography2

Stroke3

Plaques5

Plaque5

Vessels1

Diseases6

OBJECTIVE1

Bypass1

Underwent1

Diagnostic1

Obesity7

Characterization1

Mortality7

Cholesterol4

Adverse3

Lipid1

Methods1

Diabetes4

Angiogram1

Burden1

Findings1

Patients10

Factors9

Intervention1