Coronary heart disease and stroke conclusions models cardiovascular. Medical search. Frequent questions

Methods: Post 9/11 first occurrence of CVD was assessed in 37,725 responders from self-reported physician diagnosis of, or current treatment for, coronary artery disease, myocardial infarction, stroke and/or congestive heart failure from WTCHP GRC monitoring visits. (cdc.gov)
We searched EMBASE, CINAHL, Google Scholar, PubMed, and Web of Science from inception to December 2016 to identify studies that provided information on HIV/HCV coinfection and CVD, defined as coronary artery disease, congestive heart failure and stroke. (hivevidence.org)
The most common cause of mortality worldwide is cerebrovascular disease (CVD), which includes coronary heart disease (CHD), congestive heart failure, CVD and stroke, peripheral artery diseases, carotid artery diseases, and aortoiliac disease. (medscape.com)

The target population consists of working-age people who are considered high-risk for cardiovascular disease events because of a history of coronary heart disease. (ahdbonline.com)
Using Framingham risk scoring system, the probability of myocardial infarction or stroke events was calculated for a representative sample population, ages 35 to 69 years, of people at high risk for cardiovascular disease, with a history of coronary heart disease. (ahdbonline.com)
and those with a history of coronary heart disease, hypertension, stroke, diabetes, and chronic obstructive pulmonary disease (vs not having those respective condition). (cdc.gov)
2] A prediction model that and transparency of such risk adjustment models, and to widen uses a `history of coronary heart disease' as a risk factor to predict discussion on the strengths and limitations of risk adjustment models death from an acute myocardial infarction (AMI) is always going based on service claims data. (who.int)

The advent of coronary care units and early reperfusion therapy (lytic or percutaneous coronary intervention) has substantially decreased in-hospital mortality rates and has improved the outcome in survivors of the acute phase of MI. (medscape.com)
The aim of the study was to examine the usefulness of echocardiographic parameters as predictors of in-hospital outcome in patients with ACS after percutaneous coronary intervention (PCI). (hindawi.com)

An increased risk of cardiovascular disease (CVD) was reported in patients coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV), without identifying factors associated with atherosclerotic CVD (ASCVD) events. (natap.org)
and subclinical carotid artery stenosis documented by ultrasound (defined as ≥50% lumen stenosis) and aortic atherosclerotic disease (defined as an abdominal aortic aneurysm). (natap.org)
Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of mortality in the United States. (jabfm.org)
Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of mortality in the United States despite a strong emphasis on prevention, accounting for more than 800,000 deaths in 2017. (jabfm.org)
Atherosclerotic disease, the major pathophysiological process responsible for PAD, is now well recognized as causing an increased large artery pulse wave velocity (PWV) and central aortic pulse pressure (PPc). (wits.ac.za)
The primary end point was time to the occurrence of stroke or death within 30 days.Results:Of 11 016 randomized patients, 2351 (21.3%) patients had an ipsilateral atherosclerotic stenosis. (kb.se)
Aetna considers the use of chelation therapy experimental and investigational in the prevention and treatment of cancer, cardiovascular disease (e.g., atherosclerotic cardiovascular disease , coronary artery disease, individuals who had a myocardial infarction), neurodegenerative diseases (e.g. (aetna.com)
Periodontal pathogens have been found in carotid and coronary atherosclerotic plaques. (medscape.com)

Hypertension is a risk factor for cardiovascular disease (CVD), the leading cause of death in the United States. (cdc.gov)
Hypertension is a risk factor for cardiovascular disease (CVD), contributing to 35% of myocardial infarctions (MIs) and strokes, and 49% of heart failures (2). (cdc.gov)
We aimed to project the long-term effects of health insurance expansions on hypertension treatment, CVD incidence rates, and disease-related mortality rates, using a state-transition (Markov process) model that simulates the lifetime health events among cohorts of the nonelderly hypertensive population. (cdc.gov)
The model incorporated population-representative data from India on multiple risk factors that affect myocardial infarction and stroke mortality, including hypertension, hyperlipidemia, diabetes, coronary heart disease, and cerebrovascular disease. (who.int)
Despite the rise in co-morbid cardiovascular disease risk factors like hyperlipidemia and hypertension in low- and middle-income countries, tobacco control is likely to remain a highly effective strategy to reduce cardiovascular deaths. (who.int)
The high prevalence of uncontrolled hypertension is due in part to a lack of awareness: 32% of people with the disease do not know they have it [ 4 ]. (biomedcentral.com)
Compared with the non-diabetic group, the diabetic group of patients comprised more women and had more comorbidities such as hypertension, dyslipidemia, renal impairment, peripheral vascular disease and prior ischemic heart disease. (springer.com)
A reduced level of 25-hydroxyvitamin D (25-OH-vitD) in plasma, as an indicator of vitamin D deficiency, is associated with several risk factors of stroke, such as hypertension, thrombosis, atherosclerosis, and inflammation. (biomedcentral.com)
In addition, CYP24A1 polymorphisms were associated with many diseases, such as stroke, hypertension, hepatitis C virus infection and cancers. (biomedcentral.com)

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the United States. (ahdbonline.com)
Cardiovascular morbidity and mortality associated with the metabolic syndrome. (mja.com.au)
Patients with chronic coronary artery disease (CAD) and/or peripheral artery disease (PAD) have increased risks for cardiovascular (CV)-related morbidity and mortality. (ahdbonline.com)
Acute coronary syndrome (ACS) is today one of the leading causes of morbidity and mortality in the world. (hindawi.com)
Peripheral arterial disease (PAD) is a significant cause of morbidity and mortality in both economically developed and developing countries. (wits.ac.za)

Type 2 diabetes mellitus (DM) is a risk factor for cardiovascular diseases and is common among patients undergoing coronary artery bypass grafting (CABG) surgery. (springer.com)
Currently, overall cardiovascular disease affects approximately 32.2% of all type 2 diabetes mellitus (DM) patients worldwide, while cardiovascular disease is a major cause of mortality among people with type 2 DM, accounting for approximately half of all deaths [ 1 ]. (springer.com)
Is Diabetes Mellitus a Coronary Heart Disease Equivalent? (revespcardiol.org)
Several guidelines on the treatment of cardiovascular risk factors base their recommendations on the assertion that diabetes mellitus (DM) is a coronary heart disease (CHD) or cardiovascular disease (CVD) risk equivalent. (revespcardiol.org)
Several systemic diseases, such as diabetes mellitus, may increase the prevalence, incidence, or severity of gingivitis and periodontitis. (medscape.com)

To model the financial and health outcomes impact of intensive statin therapy compared with usual care in a high-risk working-age population (actively employed, commercially insured health plan members and their adult dependents). (ahdbonline.com)
Sensitivity analyses under recessive and additive models for the two outcomes with adequate data (major adverse cardiovascular events and stent thrombosis) produced results in the same direction but with larger effect sizes than the dominant model. (ahrq.gov)
In the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) clinical trial of such patients, rivaroxaban plus aspirin demonstrated a significant reduction in major adverse CV events (MACE), a composite of stroke, myocardial infarction, and CV death, and major adverse limb events (MALE), a composite of chronic and acute limb ischemia, and major amputation resulting from vascular events, versus aspirin alone. (ahdbonline.com)
Secondary outcomes were coronary and/or cerebral ASCVD events, and peripheral artery disease (PAD) ASCVD events. (natap.org)
Clinical outcomes included 30-day major adverse cardiovascular events (MACE: which included death, MI, and stroke), in-hospital complications, and long-term all-cause mortality. (springer.com)
Although number of risk scores have been developed to predict short and long term outcomes in patients with ACS [ 1 - 10 ], GRACE and TIMI risk scores are the most popular and validated ACS prediction models, recommended by contemporary guidelines [ 11 , 12 ]. (hindawi.com)
12 For example, the current Kidney Disease: Improving Global Outcomes (KDIGO) guidelines recommend the use of renin-angiotensin-aldosterone system-blocking agents including angiotensin-converting enzyme inhibitors (ACEis) or angiotensin II receptor blockers (ARBs) in patients with CKD and diabetes who have hypertensive symptoms. (ajmc.com)
All patients received aspirin, 300 to 325 mg on day 1 followed by 75 to 100 mg daily for days 2 to 30.Main Outcomes and Measures: Time to the occurrence of disabling stroke (progression of index event or new stroke) or death within 30 days, as measured by mRS at day 30. (kb.se)
Discussed accomplishments of Million Hearts, state how evidence-based strategies can help identify and address the needs of those at greatest risk for heart attack and stroke, and discuss the use of standardized treatment approaches to improve outcomes for patients at risk for heart attack and stroke. (cdc.gov)
Understanding reasons for the improvements in smoking and physical activity may support the development of targeted interventions to reverse the trends and help prevent chronic disease and adverse reproductive outcomes among women in this age group. (cdc.gov)
The surveillance of trends among women of reproductive age in indicators related to adverse birth outcomes and development of chronic disease can identify groups at increased risk and guide public health prevention and management efforts. (cdc.gov)
Therefore, understanding the dietary risk factors for cardiovascular outcomes is important in order to establish nutritional recommendations. (lu.se)

1 Hypercholesterolemia, particularly elevated lowdensity lipoprotein cholesterol (LDL-C), is strongly associated with an increased risk of CVD, including coronary heart disease (CHD) events (ie, myocardial infarction [MI], angina, coronary revascularization) and stroke. (ahdbonline.com)
The endpoints were major adverse cardiovascular events (MACE), including all-cause mortality, myocardial reinfarction, and target vessel revascularization (TVR). (hindawi.com)
Despite of the use of current guideline-recommended therapies, including prompt coronary revascularization, dual antiplatelet therapy, and intensive lipid-lowering therapy, ACS patients still have a poor prognosis [ 1 - 3 ]. (hindawi.com)

Descending thoracic aneurysm and renal or mesenteric artery disease were excluded. (natap.org)
Gouty arthritis is associated with an excess risk of acute MI, and this is not explained by its well-known links with renal function, metabolic syndrome, diuretic use, and traditional cardiovascular risk factors. (natap.org)
Individuals with inflammatory diseases, cardiomyopathy, renal diseases (detected by hematuria tests) or other severe diseases were excluded from this study. (biomedcentral.com)
About 1 in 3 US adults with diabetes has CKD, and CKD with diabetes accounts for approximately 39% of end-stage renal disease (ESRD) cases in the United States. (ajmc.com)
Exposure groups achieved excellent covariate balance, including key laboratory results, and expected associations between glimepiride and hypoglycemia (HR 2.38 [95% CI 1.79-3.13]) and between linagliptin and end-stage renal disease (HR 1.08 [0.66-1.79]) were replicated. (diabetesjournals.org)
Hantaviruses cause 2 acute diseases: hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). (cdc.gov)
HFRS can cause pulmonary complications and HCPS can cause renal signs and symptoms, suggesting that these 2 diseases might have more in common than previously believed ( 5 , 6 ). (cdc.gov)
These specific conditions in the oral cavity may create foci of infection that can affect many other vital systems, such as the cardiovascular and renal systems. (medscape.com)

P gingivalis has also been found in carotid and coronary atheromas. (medscape.com)

Chronic coronary artery disease (CAD) and peripheral artery disease (PAD) are manifestations of atherosclerosis that result from the narrowing and blockage of the coronary and limb arteries, respectively. (ahdbonline.com)
Peripheral artery disease (PAD) is an important risk factor for cardiovascular disease. (researchsquare.com)
However, there are a little research on the association between the AST/ALT ratio and Peripheral artery disease (PAD). (researchsquare.com)
The association between AST / ALT and peripheral arterial disease (PAD), which was defined as ABI ≤ 0.9 in either leg, was estimated by a multivariate logistic regression model. (researchsquare.com)
Peripheral artery disease (PAD), a kind of arteriosclerosis diseases, has become the third leading cause of arteriosclerosis cardiovascular morbidity next to stroke and coronary artery disease [1] . (researchsquare.com)
Peripheral arterial disease has become a global health problem [4] , with high mortality and cardiovascular morbidity [4] . (researchsquare.com)
Potential novel approaches to risk identification in advanced peripheral arterial disease. (wits.ac.za)
Collagen turnover is associated with cardiovascular autonomic and peripheral neuropathy in type 1 diabetes: novel pathophysiological mechanism? (ku.dk)

If a model is derived in a particular population, the prevalence and impact of any missing risk factors is tacitly embedded in coefficients of the risk equations. (biomedcentral.com)
The model inputs were taken from the COMPASS study (ie, the efficacy and safety of rivaroxaban plus aspirin vs aspirin), Optum Integrated Database (ie, the prevalence of chronic CAD and/or PAD, incidence rates, and healthcare costs of MACE, MALE, and major bleeding), and the RED BOOK (ie, wholesale drug acquisition costs). (ahdbonline.com)
PA can provide a wide range of favorable response in cardiovascular system such as improving the dynamics of cardiovascular system and reducing the prevalence of coronary heart disease and cardiomyopathy [ 7 ]. (biomedcentral.com)
The prevalence of noncommunicable diseases (NCDs) is rising rapidly and they are no longer restricted to highly industrialized countries. (who.int)
The prevalence gap widened between the most and least populous municipalities for Complete Streets policies (from a gap of 33.6 percentage points [PP] in 2014 to 54.0 PP in 2021) and for zoning codes requiring block sizes that were walkable distances (from 11.8 PP to 41.4 PP). CONCLUSION: To continue progress, more communities could consider adopting physical activity-friendly policies and design features. (cdc.gov)
RESULTS AND CONCLUSIONS: The overall joint prevalence was 8.5% (95% CI, 8.0-9.0). (cdc.gov)
We reviewed a decade of data from all patients with coronary heart disease enrolled in a single CR center (University of Michigan) to identify the prevalence of low-risk factors, which may inform on consideration for participation in alternative models of CR. (journaltocs.ac.uk)
The high prevalence of secondhand smoke and consequently the increased risk of coronary heart disease in the U.S. general population have important implications for public health. (nationalacademies.org)

In combination, these tobacco control interventions could avert 25% of myocardial infarctions and strokes (95% CI: 17%-34%) if the effects of the interventions are additive. (who.int)
Myocardial infarction (MI) due to coronary artery disease is a leading cause of death in the United States, where more than 1 million people have acute myocardial infarctions (AMIs) each year. (medscape.com)
2009) recently estimated that at the 1999 to 2004 levels, passive smoking leads to 21,800 to 75,100 deaths from coronary heart disease and 38,100 to 128,900 myocardial infarctions annually. (nationalacademies.org)

ABSTRACT: The CASPIAN Study aims to implement a school-based surveillance system for prevention of noncommunicable diseases from childhood in the Islamic Republic of Iran. (who.int)
We used a random-effects model to abstract and pool data on the hazard ratios (HRs) for CVD. (hivevidence.org)

To provide evidence of the relationship of Mediterranean diet (MD) on incidence/mortality for cardiovascular disease (CVD), coronary/ischemic heart disease (CHD)/acute myocardial infarction (AMI) and stroke (ischemic/hemorrhagic) by sex, geographic region, study design and type of MD score (MDS). (nih.gov)
The incidence of arteriosclerosis cardiovascular disease is rapidly increasing as a result of the improvement in living standards, changes in diet and living habits in China. (researchsquare.com)
This large, nationwide, prospective multicenter cohort including HCV-HIV coinfected patients with a long follow-up, showed a high incidence of ASCVD events, especially acute coronary syndrome and PAD. (natap.org)
INTRODUCTION/OBJECTIVES: The Centers for Disease Control and Prevention recognizes routine vaccination, sufficient sleep, and adequate physical activity as behavioral approaches to reduce the incidence of influenza. (cdc.gov)
However, the incidence of stroke in patients investigated for OSA has been assessed in a limited number of studies reporting conflicting results on the association between the apnoea-hypopnoea index (AHI) and stroke incidence [ 1 - 3 ]. (ersjournals.com)
Within a large multicentre clinic-based cohort of patients investigated for OSA, we hypothesised that PSG-derived indices of SASHB and HRV could predict stroke incidence. (ersjournals.com)

2-4 Landmark statin studies targeting LDL-C lowering have shown dramatic reductions in heart attacks, stroke, and cardiac death. (ahdbonline.com)
Background: Over 90,000 rescue and recovery responders to the September 2001 World Trade Center (WTC) attacks were exposed to toxic materials that can impair cardiac function and increase cardiovascular disease (CVD) risk. (cdc.gov)
Although a recent joint society scientific statement (the American Association of Cardiovascular Pulmonary Rehabilitation, the American Heart Association, and the American College of Cardiology) suggests home-based cardiac rehab (CR) is appropriate for low- and moderate-risk patients, there are no paradigms to define such individuals with coronary heart disease. (journaltocs.ac.uk)

Centers for Disease Control and Prevention. (cdc.gov)
Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland coronary prevention study. (mja.com.au)
The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
Investigators noted that the ceramide-phospholipid risk score was comparable and synergistic predictive performance compared with previously published CVD risk models for secondary prevention. (hcplive.com)
If smoking does interact with BMI, this would have ramifications for estimates of disease burden due to these two important and modifiable risk factors, and have implications for disease prevention. (biomedcentral.com)
Nowhere are the "blessings of the grape" so evident as in prevention of cardiovascular disease. (lifeextension.com)
The Multiple Risk Factor Intervention Trial (MRFIT), a randomized primary cardiovascular prevention trial conducted and supported by the National Heart, Lung, and Blood Institute in collaboration with the MRFIT investigators, is one such study with the information on traditional and other confounding risk factors that has been unaccounted for in previous studies. (natap.org)
1974). In addition, the 1990 report The Health Benefits of Smoking Cessation: A Report of the Surgeon General (HHS, 1990) and the National Cancer Institute's Monograph 8: Changes in Cigarette-Related Disease Risks and Their Implications for Prevention and Control (NCI, 1997) discussed the cardiovascular benefits of smoking cessation. (nationalacademies.org)
Its influence on many cardiovascular risk factors, combined with its proven effect in reducing the risk of cardiovascular events in primary prevention, has boosted scientific interest in this age-old nutritional model. (mdpi.com)
I'm Loretta Jackson-Brown and I'm representing the Clinician Outreach and Communication Activity, COCA, with the Emergency Risk Communication Branch at the Center for Disease Control and Prevention. (cdc.gov)
Cancer and heart disease are the second and third leading causes of death in this population, but little attention has focused on these women's needs for primary prevention of chronic disease outside of routine screening for cancer (3,4). (cdc.gov)
ATSDR received considerable assistance in this work from the Cardiovascular Diseases Branch of the Centers for Disease Control & Prevention (CDC). (cdc.gov)

Reductions in cardiovascular and stroke events reported in clinical trials with aggressive statin therapy were applied to these cohorts. (ahdbonline.com)
Aggressive low-density lipoprotein cholesterol-lowering therapy for working-age people at high risk for cardiovascular events and with a history of heart disease appears to have a significant potential to reduce the rate of clinical events and is cost-neutral for payers. (ahdbonline.com)
Clinical value of the metabolic syndrome for long term prediction of total and cardiovascular mortality: prospective, population based cohort study. (mja.com.au)
In clinical medicine, cardiovascular risk is increasingly accepted as the appropriate criterion to use to identify those who will most benefit from interventions designed to prevent cardiovascular disease and death. (biomedcentral.com)
We hypothesized that different types of BA measures (clinical, inflammatory, and genomic) make unique contributions to age-related disease risk and all-cause mortality. (deepdyve.com)
ACS is a group of clinical syndromes, including non-ST elevation acute coronary syndrome (NSTE-ACS) and ST elevation acute myocardial infarction (STEMI), with the pathogenesis of vulnerable plaque rupture, subsequent red or white thrombosis, thereby resulting in incomplete or complete vascular occlusion [ 4 ]. (hindawi.com)
Recently, numerous studies have shown that the fibrinogen-to-albumin ratio (FAR) does not only have a high prognostic value in certain types of cancer including gastric, colorectal, and gallbladder cancer [ 8 - 10 ] but also have an association with the presence and poor clinical outcome of cardiovascular disease [ 11 - 14 ]. (hindawi.com)
However, none has addressed the association between FAR and severity of coronary artery disease (CAD), clinical outcome in NSTE-ACS patients firstly implanted with drug-eluting stent (DES). (hindawi.com)
Surveys were linked prospectively to clinical hospital records, and Cox proportional hazards models were used to estimate the risk of cardiovascular disease events or death according to oral hygiene. (bmj.com)
Previous smaller epidemiological studies that have examined the association between oral health and cardiovascular disease have generally used clinical assessments to identify periodontal disease. (bmj.com)
Incorporation of such developed model should facilitate research, clinical decisions, and optimizing treatment strategy in selected high risk ACS patients. (hindawi.com)
ACS is defined as "any group of clinical symptoms compatible with acute myocardial ischemia", which includes unstable angina (UA) and myocardial infarction (MI), with or without ST-segment elevation according to American Heart Association [ 13 ]. (hindawi.com)
As clinical use of arterial stiffness is growing in popularity, the efficacy of this useful tool in assessing cardiovascular risk reduction among patients with OSA treated with CPAP needs to be further explored. (acc.org)
Whether physiological markers of SASHB and HRV might be useful in a clinical setting for identifying those patients with OSA at risk for stroke remains to be determined. (ersjournals.com)
The addition of key condition-specific clinical data points at the time of hospital admission will dramatical y improve model performance. (who.int)
Was the death specific clinical conditions (i.e. acute myocardial infarction, coronary of this patient expected? (who.int)
Based on these premises, taking advantage of the reliability of computed tomography perfusion (CTP) imaging in the estimation of cerebral tissue viability in both clinical and research settings, [ 4 ] we conducted a case-control study comparing CTP maps of migraineurs and nonmigraineurs patients with acute ischemic stroke aimed at investigating whether a personal history of migraine is associated with vulnerability to brain ischemia. (medscape.com)

Performance could be further improved by using summary risk prediction scores such as the EUROSCORE II for coronary artery bypass graft surgery or the GRACE risk score for acute coronary syndrome. (who.int)
Is my rate of heart failure readmissions artery bypass graft (CABG) surgery, pneumonia and acute stroke). (who.int)

The outcome events were cardiovascular diseases (CVDs), while the independent variable was total daily physical activity. (biomedcentral.com)
Cox proportional hazards models tested the association of each BA estimate with each outcome adjusting for covariates. (deepdyve.com)
Using real-world data (RWD) from three U.S. claims data sets, we aim to predict the findings of the CARdiovascular Outcome Trial of LINAgliptin Versus Glimepiride in Type 2 Diabetes (CAROLINA) comparing linagliptin versus glimepiride in patients with type 2 diabetes (T2D) at increased cardiovascular risk by using a novel framework that requires passing prespecified validity checks before analyzing the primary outcome. (diabetesjournals.org)
We registered the protocol ( NCT03648424 , ClinicalTrials.gov) before evaluating the composite cardiovascular outcome based on CAROLINA's primary end point. (diabetesjournals.org)
Linagliptin was associated with a 9% decreased risk in the composite cardiovascular outcome with a CI including the null (HR 0.91 [0.79-1.05]), in line with noninferiority. (diabetesjournals.org)
In a nonrandomized RWD study, we found that linagliptin has noninferior risk of a composite cardiovascular outcome compared with glimepiride. (diabetesjournals.org)
When designing a risk prediction model, patient-proximate variables with a sound theoretical or proven association with the outcome of interest should be used. (who.int)

Within Medicare and two commercial claims data sets (May 2011-September 2015), we identified a 1:1 propensity score-matched (PSM) cohort of T2D patients 40-85 years old at increased cardiovascular risk who initiated linagliptin or glimepiride by adapting eligibility criteria from CAROLINA. (diabetesjournals.org)

Understanding the biologic processes of aging and how these processes confer susceptibility to chronic disease may lead to successful interventions that delay aging and improve health span (3). (deepdyve.com)
Some potentially modifiable risk factors and chronic conditions cause significant disease and death during pregnancy and promote the development of chronic disease. (cdc.gov)

This inverse association includes CHD and ischemic stroke, but apparently not hemorrhagic stroke. (nih.gov)
reported that CYP24A1 rs1570669 was linked to a reduced risk of stroke, and rs6068816 could increase susceptibility to ischemic stroke [ 12 ]. (biomedcentral.com)
The trial included 11 016 patients with a noncardioembolic, nonsevere ischemic stroke or high-risk TIA, including 10 803 with modified Rankin Scale score (mRS) recorded at 30 days.Interventions: Ticagrelor (180-mg loading dose on day 1 followed by 90 mg twice daily for days 2-30) or placebo within 24 hours of symptom onset. (kb.se)
Disabling stroke was defined by mRS greater than 1.Results: Among participants with 30-day mRS greater than 1, mean age was 68.1 years, 1098 were female (42.6%), and 2670 had an ischemic stroke (95.8%) as a qualifying event. (kb.se)
Multicenter cohort study of patients with acute ischemic stroke who underwent a brain computed tomography perfusion and were scheduled to undergo reperfusion therapy. (medscape.com)
Migraine is likely to increase individual vulnerability to ischemic stroke during the process of acute brain ischemia and might represent, therefore, a potential new therapeutic target against occurrence and progression of the ischemic damage. (medscape.com)
A large body of literature supports a link between migraine, especially migraine with aura, and ischemic stroke. (medscape.com)

This meta-analysis of prospective cohort studies suggests that ED significantly increases the risk of CVD, coronary heart disease, stroke, and all-cause mortality, and the increase is probably independent of conventional cardiovascular risk factors. (qxmd.com)
In this regard, carotid IMT measurements may be useful.The extent to which human HIV is associated with increases in IMT independent of conventional cardiovascular risk factors is unclear. (wits.ac.za)

We developed a state-transition model to simulate the lifetime health events of the population aged 25 to 64 years. (cdc.gov)
We modeled the effects of insurance coverage expansions on the basis of published findings on the relationship between insurance coverage, use of antihypertensive medications, and CVD-related events and deaths. (cdc.gov)
Such an increase in treatment rate is estimated to lead to 111,000 fewer new coronary heart disease events, 63,000 fewer stroke events, and 95,000 fewer CVD-related deaths by 2050. (cdc.gov)
Our analysis models the cost impact of aggressive statin therapy for a commercially insured cohort of members at high risk for secondary events from CVD as a result of a history of CHD. (ahdbonline.com)
Coronary heart disease (CHD) events, ischaemic stroke events, and total mortality. (mja.com.au)
A diagnosis of MetS provides additional prediction of CHD events, stroke events, and total mortality beyond that provided by other conventional risk factors. (mja.com.au)
Most CVD models focus on coronary heart disease (CHD) events, such as myocardial infarction. (biomedcentral.com)
While investigators concluded that ceramide-phospholipid risk score showed comparable and synergistic predictive performance when compared with previously published CVD risk models, they also found that there was variability in the risk of CVD events in patients with coronary artery disease. (hcplive.com)
Associations were nonstatistically significant in meta-analyses of loss-of-function alleles and all-cause mortality, acute coronary syndromes, stroke, and bleeding events. (ahrq.gov)
Many commonly used prescription medications have cardiovascular adverse effects, yet the cumulative risk of cardiovascular events associated with the concurrent use of these medications is unknown. (usc.edu)
We examined the association between the concurrent use of prescription medications with known risk of a major adverse cardiovascular event (MACE) ("MACE medications") and the risk of such events among older adults. (usc.edu)
In this community-based cohort of older adults with no prior cardiovascular disease, the use of MACE medications was independently and consistently associated with an increased risk of such events in a dose-response fashion. (usc.edu)
whereas undetectable baseline viral load (HR 0.41, 95% CI, 0.18-0.96) was associated with coronary and/or cerebral events. (natap.org)
As in previous studies [34-36], we found that undetectable baseline HIV RNA was associated with a reduced risk of coronary and/or cerebral ASCVD events. (natap.org)
Traditional CVD risk factors were predictive of coronary and/or cerebral ASCVD events, whereas undetectable baseline HIV RNA was protective. (natap.org)
PAD ASCVD events, in particular lower limb artery disease, was predominant and requires active diagnosis and intensive management, while controlling modifiable traditional cardiovascular risk factors. (natap.org)
HCV-related factors did not appear to be associated with the risk of cardiovascular events. (natap.org)
Other adjudicated CVD events were episodes of heart failure requiring hospitalization and venous thromboembolic disease requiring hospitalization. (natap.org)
Simultaneously, blood stasis, endothelial damage, and hypercoagulability were also considered risk factors for acute coronary thrombotic events [ 7 ]. (hindawi.com)
Results There were a total of 555 cardiovascular disease events over an average of 8.1 (SD 3.4) years of follow-up, of which 170 were fatal. (bmj.com)
In about 74% (411) of cardiovascular disease events the principal diagnosis was coronary heart disease. (bmj.com)
8 C reactive protein and fibrinogen are sensitive markers used to evaluate the inflammatory status of an individual, and the results of prospective longitudinal studies indicate that these markers might be useful predictors for future cardiovascular events in various populations. (bmj.com)
These recommendations were based on numerous studies showing that statins are effective in reducing low-density lipoprotein cholesterol levels, and the risk of death and recurrent coronary and cardiovascular events in those with a history of ASCVD, even in older adults. (jabfm.org)
OBJECTIVE -To investigate whether cardiovascular risk factors cluster with hyperinsulinemia in elderly type 2 diabetic subjects and, if so, whether this clustering predicts coronary heart disease (CHD) events during a 7-year follow-up. (diabetesjournals.org)
Cox regression models were used to investigate whether these clusters (factors) predict CHD events (CHD death or nonfatal myocardial infarction) during a 7-year follow-up in 229 type 2 diabetic subjects aged 65-74 years. (diabetesjournals.org)
Although ankle-brachial index may detect PAD, more general screening tools to detect those at risk of cardiovascular events are required. (wits.ac.za)
It's been found that people who had previously experienced coronary events had even lower mortality rates. (calendar.com)
Recall that Million Hearts was initially going to measure effects on high-risk patients, but there weren't going to be enough events, so they expanded to medium-risk patients. (medscape.com)
So, this tells that the extra treatment in the Million Hearts model may have led to a very small reduction in CV events, but at the cost of more total hospitalizations. (medscape.com)

Most recently, in The Health Consequences of Involuntary Exposure to Tobacco Smoke (HHS, 2006), it concluded that exposure to secondhand smoke could have immediate adverse effects on the cardiovascular system in adults and that it causes coronary heart disease. (nationalacademies.org)
Smoking, which has an adverse effect on periodontal health, also affects this overall disease condition. (medscape.com)

Methods and Findings A microsimulation model was developed to quantify the differential effects of various tobacco control measures and pharmacological therapies on myocardial infarction and stroke deaths stratified by age, gender, and urban/rural status for 2013 to 2022. (who.int)
The metabolic syndrome and mortality from cardiovascular disease and all-causes: findings from the National Health and Nutrition Examination Survey II Mortality Study. (mja.com.au)
Current findings emphasize that higher AST / ALT level can be biomarkers for cardiovascular diseases. (researchsquare.com)
In just the past decade, striking new findings have been made on how components of red grapes (including both skin and seeds) affect vascular health, ranging from increasing vital nitric oxide (critical in maintaining endothelial function) to protecting against heart muscle damage. (lifeextension.com)
Conclusions Our findings suggest BA measures may be complementary in predicting risk for mortality and age-related disease. (deepdyve.com)
The findings show that persons affected by heart disease had different experiences with technology and expectations toward counseling, while all rehabilitees expected technology to be easy to use and their experiences to be smooth and problem-free. (jmir.org)

Methods Study Sample The Framingham Heart Study (FHS) is a community-based longitudinal cohort study initiated in 1948 to study determinants of cardiovascular disease (CVD) and its risk factors. (deepdyve.com)

Hence, in addition to traditional risk factors, it is critical to find new markers that could predict PAD more easily and prevent cardiovascular death earlier [4] . (researchsquare.com)
In this capacity, she has worked across federal and private partners to execute evidence-based strategies to prevent cardiovascular diseases and improve health. (cdc.gov)

In conclusion, in the context of an increased PPc,carotid-femoral PWV is markedly reduced in CLI. (wits.ac.za)
Periodontal disease permits organisms to enter deep systemic tissues, such as the carotid atheroma. (medscape.com)
This marker measures the thickness of the wall of the carotid arteries and can predict the possibility of developing cardiovascular diseases later on in life. (lu.se)

We also conducted a multivariable logistic regression analysis to determine whether sociodemographic characteristics are associated with statin use during the 3 years that followed the publication of the 2013 American College of Cardiology/American Heart Association (ACC/AHA) guideline (2014 through 2016). (jabfm.org)
Onco-cardiology, a new academic field, aims to improve the quality of life and prognosis of cancer patients and survivors with cardiovascular diseases (CVD). (go.jp)
As a former Senior Vice President for Science and Quality at the American College of Cardiology, Dr. Wright oversaw the development of guidelines, performance measures and appropriate use criteria to include the National Cardiovascular Data Registry. (cdc.gov)

There are several reasons for calculating the risk of cardiovascular disease in an individual or a population. (biomedcentral.com)

In this study, we sought to evaluate the relationship between FAR and severity of CAD, long-term prognosis in non-ST elevation acute coronary syndrome (NSTE-ACS) patients firstly implanted with drug-eluting stent (DES). (hindawi.com)
The main objective of our study was to investigate the impact of DM type 2, and its treatment subgroups, on short- and long-term mortality in patients with acute coronary syndrome (ACS) who undergo CABG. (springer.com)
The study included 1307 patients enrolled from the biennial Acute Coronary Syndrome Israeli Survey between 2000 and 2016, who were hospitalized for ACS and underwent CABG. (springer.com)
Arrhythmogenesis early in the course of an acute coronary syndrome (ACS), manifested often as polymorphic ventricular tachycardia (VT) or ventricular fibrillation (VF) is observed in a minority of patients with acute ischemia, and it is often associated with genetic predisposition. (medscape.com)
Different ways have been used to stratify risk in acute coronary syndrome (ACS) patients. (hindawi.com)

However, we noticed that elevated STB appeared in unstable angina pectoris (UAP) patients with diffused coronary lesions. (journaltocs.ac.uk)

All controls were determined to be free of cardiovascular disease. (biomedcentral.com)
Subjects Patients aged 30-84 years who were free of cardiovascular disease and not taking statins between 1 January 1994 and 30 April 2010: 2 343 759 in the derivation dataset, and 1 267 159 in the validation dataset. (bmj.com)

2 The risk of heart failure, atrial fibrillation, stroke, and coronary heart disease is approximately double in patients with CKD. (ajmc.com)

The designated effects were risk ratio (RR) and hazard ratio (HR). The random effects model was used to combine the results. (biomedcentral.com)

A recent study has found that a ceramide- and phospholipid-based risk score, not LDL cholesterol (LDL-C), can efficiently predict residual cardiovascular disease (CVD) event risk in patients with coronary heart disease (CHD). (hcplive.com)
It is not clear if each of these different measures of BA captures unique information or adds complementary information over and above chronological age (CA) to predict disease risk and life span. (deepdyve.com)

Population-based studies have demonstrated that the sleep apnoea specific hypoxic burden (SASHB), an easily derived signal from polysomnography (PSG), predicts cardiovascular mortality and incident heart failure [ 4 , 5 ]. (ersjournals.com)

RESEARCH DESIGN AND METHODS -Clustering of cardiovascular risk factors was analyzed by factor analysis. (diabetesjournals.org)
Recently, factor analysis and principal components analysis, statistical methods for studies of intercorrelating variables, have been applied to investigate the clustering of cardiovascular risk factors in both nondiabetic and diabetic subjects ( 4 , 5 , 6 , 7 ). (diabetesjournals.org)

Health care providers need to model future patterns of need for health services, and to identify the cost effectiveness of different intervention strategies. (biomedcentral.com)
The 3 studies that investigators pooled data from were the Western Norway Coronary Angiography Cohort (WECAC), the Long-Term Intervention with Pravastatin in Ischemic Disease (LIPID) trial, and Langzeiterfolge der KARdiOLogischen Anschlussheilbehandlung (KAROLA). (hcplive.com)
Conclusions Compared with using a 10 year QRISK2 score, a lifetime risk score will tend to identify patients for intervention at a younger age. (bmj.com)
Foy believes this study is a wash for the Million Hearts intervention. (medscape.com)
We screened 1,332 women for cardiovascular disease risk factors and randomly assigned 1,093 women to 2 groups: an enhanced intervention (n = 552) or usual care (n = 541). (cdc.gov)
The program resulted in improvements in the CVD risk profile, as measured by the 10-year coronary heart disease risk, of women who participated in the intervention group compared with women in usual care (10). (cdc.gov)

Erectile dysfunction and risk of cardiovascular disease: meta-analysis of prospective cohort studies. (qxmd.com)
Our goal was to evaluate the association between erectile dysfunction (ED) and risk of cardiovascular disease (CVD) and all-cause mortality by conducting a meta-analysis of prospective cohort studies. (qxmd.com)

In proportional hazards models that included conventional risk factors, but excluded variables used to define the presence of MetS, MetS was a significant predictor of CHD, stroke and total mortality. (mja.com.au)
Hazards ratios (HRs) and 95% confidence intervals (CIs) for BMI by cigarette smoking status were estimated using Cox proportional hazard models. (biomedcentral.com)
The Cox proportional hazard models were introduced to investigate the association between total physical activity and CVDs, reporting as hazard ratios (HR) and 95% confidence intervals (CIs). (biomedcentral.com)
Factors associated with ASCVD were identified using cause-specific Cox proportional hazards models. (natap.org)
Cox proportional hazards models in the derivation cohort to derive risk equations accounting for competing risks. (bmj.com)
Cox proportional hazards and competing risks models evaluated associations between GEH electrocardiographic parameters and SCD. (elsevierpure.com)

The same cascade causes platelets, the tiny cell-like fragments responsible for blood clotting, to cluster together (aggregate) excessively, increasing the risk of clot formation that can produce ischemic heart attacks and strokes. (lifeextension.com)
At the conclusion of today's session, the participant will be able to describe the key components of Million Hearts and the targets that must be met to prevent one million heart attacks and strokes. (cdc.gov)

A growing number of associations suggest assessing the value of new biomarkers in predicting risk of cardiovascular disease [10-12] . (researchsquare.com)
We will review several projects based on the use of panels of biomarkers for a better understanding of risk of disease and prognosis. (lu.se)

Pooled relative risks (RRs) were calculated using random-effects models. (nih.gov)
The overall combined relative risks for men with ED compared with the reference group were 1.48 (95% confidence interval [CI]: 1.25 to 1.74) for CVD, 1.46 (95% CI: 1.31 to 1.63) for coronary heart disease, 1.35 (95% CI: 1.19 to 1.54) for stroke, and 1.19 (95% CI: 1.05 to 1.34) for all-cause mortality. (qxmd.com)
9 10 11 12 Lifetime risks which measure the cumulative risk of developing a disease during the remainder of an individual's life 13 would reflect this relatively high risk and, given that lifetime risk estimates provide assessment over the full life course, they may provide a more appropriate assessment of future risks than estimates limited to 10 years, particularly at younger ages. (bmj.com)

Conclusions Smoke-free laws and substantially increased tobacco taxation appear to be markedly potent population measures to avert future cardiovascular deaths in India. (who.int)
Conclusions: WTCHP GRC members with 9/11/2001 exposures had substantially higher CVD risk than those initiating work afterward, consistent with observations among WTC-exposed New York City firefighters. (cdc.gov)
The acute event costs were $31,063 for heart failure, $21,087 for stroke, and $21,016 for myocardial infarction in the first 4 months after the incident event, which all decreased substantially in subsequent 4-month cycles. (ajmc.com)
Their data provide evidence that limitation of secondhand-smoke exposure should reduce risk of mortality from coronary heart disease substantially. (nationalacademies.org)

A multi-center, population-based study from the Atherosclerosis Risk in Communities (ARIC) study of a cohort of 3669 community-dwelling adults aged 61-86 years with no history of cardiovascular disease who reported the use of at least one medication between September 2006 and August 2013 were followed up until August 2015. (usc.edu)
1 Inflammation plays an important role in the pathogenesis of atherosclerosis, and markers of low grade inflammation have been consistently associated with a higher risk of cardiovascular disease. (bmj.com)
Many cardiovascular diseases evolve from a phenomenon called atherosclerosis. (lu.se)

The aim of this study of type 2 diabetic patients in the Swedish National Diabetes Register was to study the associations of BMI, overweight (BMI 25-29.9 kg/m 2 ) and obesity (BMI ≥ 30 kg/m 2 ) with cardiovascular disease in type 2 diabetes, as these associations have not previously been clarified. (springer.com)
The aim of the present study, based on data from the Swedish National Diabetes Register, was to describe the associations between BMI, overweight and obesity, fatal or non-fatal CHD, stroke, CVD and total mortality, in female and male type 2 diabetic patients aged 30-74 years. (springer.com)
CONCLUSIONS -IRS is a risk factor for CHD in elderly type 2 diabetic men. (diabetesjournals.org)

These associations persisted in propensity score-matched analyses and among new users of MACE medications, never users of cardiovascular medications and subgroups of participants with increased risk of MACE. (usc.edu)

Previous studies showed that fibrinogen-to-albumin ratio (FAR) regarded as a novel inflammatory and thrombotic biomarker was the risk factor for coronary artery disease (CAD). (hindawi.com)
The association between oral hygiene and inflammatory markers and coagulation was examined in a subsample of participants (n=4830) by using general linear models with adjustments. (bmj.com)
Thus, oral infections might add to the inflammatory burden of the individual and result in increased levels of cardiovascular risk based on serum C reactive protein and fibrinogen concentrations as a consequence of the systemic inflammatory response subsequent to low grade chronic infections. (bmj.com)
Immunosuppressive drug therapy and any disease (eg, HIV infection) resulting in suppression of the normal inflammatory and immune mechanisms can cause or enhance severe periodontal diseases. (medscape.com)
[ 5 , 7 ] Although the underlying mechanisms are complex, the chronic inflammatory state and microbial burden in people with periodontal disease may predispose them to cardiovascular diseases in ways proposed for other infections. (medscape.com)

The model projected that currently anticipated health insurance expansions would lead to a 5.1% increase in treatment rate among hypertensive patients. (cdc.gov)

Anatomy11

Organisms2

Diseases57

Chemicals and Drugs41

Analytical, Diagnostic and Therapeutic Techniques and Equipment72

Psychiatry and Psychology6

Phenomena and Processes33

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena6

Technology, Industry, Agriculture2

Information Science9

Named Groups5

Health Care58

Geographicals22

Congestive heart f3

History of coronary heart d4

Percutaneous coronary int2

Atherosclerotic8

Hypertension9

Morbidity and morta5

Diabetes mellitus5

Outcomes12

Revascularization3

Renal8

Found in carotid and coronary1

Peripheral8

Prevalence8

Myocardial infarctions3

Abstract2

Incidence6

Cardiac3

Prevention12

Clinical17

Artery bypass2

Outcome7

Increased Cardiovascular Risk1

Chronic Disease2

Ischemic stroke7

Independent of conventional cardiovascular risk factors2

Events29

Adverse2

Findings6

Cohort study1

Prevent cardiovascular2

Carotid3

Cardiology3

Calculating the risk of cardiovascular1

Acute coronary5

Unstable angina pectoris1

Free of cardiovascular disease2

Atrial fibrillation1

Hazard ratio1

Predict2

Mortality and incident1

Methods2

Intervention6

Meta-Analysis2

Proportional6

Attacks and strokes2

Biomarkers2

Risks3

Substantially4

Atherosclerosis3

Type 2 diabetic3

MACE1

Inflammatory5

Hypertensive patients1