AtherosclerosisSubcutaneous adipose tissueAngiographyComputed tomographyPercutaneous coronary intCalcificationEpicardial adipose tissue thicknessAcute coronaryInflammationDiseaseArteriesWhite adiposPerivascularInflammatoryCardiovascularThicknessSeverityCalciumIntra-abdominalEndocrineMortalitySecretionMetabolic syndromeAdipokinesPlaqueHeartCardiacPatientsElevation myocardialDiabetesAdiposityRiskObesityPharmacologyLiver
Atherosclerosis10
- As it may play a role in coronary atherosclerosis in patients with diabetes, reducing EAT volume through physical exercise, improved diet and pharmaceutical interventions may improve future cardiovascular risk outcomes in this population. (researchsquare.com)
- Objective: To examine the relationship of pericardial adipose tissue (PAT) with coronary artery calcification in the Multi-Ethnic Study of Atherosclerosis. (johnshopkins.edu)
- This study assessed the link between local inflammation in adjacent epicardial adipose tissue (EAT) and coronary arterial atherosclerosis in fresh cadavers. (tokushima-u.ac.jp)
- George Nikov Chaldakov (Bulgarian: Георги Ников Чалдъков) born February 23, 1940, in Burgas, Bulgaria, is a Bulgarian vascular biologist well known for his contributions to the study of secretory function of vascular smooth muscle cells, and the role of neurotrophins and perivascular adipose tissue in pathogenesis of atherosclerosis. (wikipedia.org)
- We have shown epicardial fat measured by this clinical research tool to be associated with coronary atherosclerosis, coronary calcium progression, major adverse cardiovascular events and myocardial ischemia. (cedars-sinai.edu)
- In this review, we outline recent findings on the roles of EAT in the pathogenesis of coronary atherosclerosis. (go.jp)
- Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient partitioning. (nature.com)
- analyses, as well as others (8-11), support the hypothesis that adipose tissue-secreted factors may indeed be potent modulators of inflammation-related disorders such as obe- sity, type 2 diabetes, metabolic syndrome, atherosclerosis, inflammatory bowel disease, thyroid-associated (Graves') ophthalmopathy, breast cancer, and nonalcoholic fatty liver disease. (123dok.org)
- There is a recent line of research favoring hypothetic allergic mechanisms in the genesis of atherosclerosis and, consequently, coronary artery disease (CAD), among which Interleukin (IL)-17 appears to be a key cytokine regulating local tissue inflammation. (biomedcentral.com)
- Atherosclerosis accounts for up to 80% of cholesterol (LDL-C) and the total choles- deaths in diabetic patients due to coronary terol/HDL-C ratio (TC/HDL-C) [ 1 ]. (who.int)
Subcutaneous adipose tissue3
- We aimed to determine whether DNA methylation and mRNA levels of the ABCA1 and ABCG1 genes in EAT and subcutaneous adipose tissue (SAT) were associated with CAD. (biomedcentral.com)
- Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the framingham heart study. (scielosp.org)
- 1.2 - Relative effects of simple, refined and unrefined carbohydrate on cardiometabolic risk factors, macrophage cholesterol homeostasis, subcutaneous adipose tissue macrophage infiltration/inflammatory gene expression, and intestinal microbiome. (usda.gov)
Angiography11
- CT coronary angiography can detect coronary plaque with high resolution, estimate the degree of functional stenosis and characterise plaque features. (bmj.com)
- Consequently, invasive coronary angiography (ICA) became the gold standard for diagnosis of CAD. (bmj.com)
- A total of 164 inpatients received single-photon emission computerized tomography-myocardial perfusion imaging (SPECT/MPI) and coronary angiography (CAG) between March 2018 and October 2019 at the Third Affiliated Hospital of Soochow University were enrolled in the retrospective cross-sectional study. (amegroups.org)
- This study was conducted on sixty patients who presented with symptoms of coronary artery disease and attended elective coronary angiography to rule out coronary artery disease. (springeropen.com)
- Standardized measurement and characterization of coronary plaque from coronary CT angiography (AutoPlaque software). (cedars-sinai.edu)
- We have shown low-attenuation noncalcified plaque quantified from coronary CT angiography predicts ischemia and future adverse cardiac events. (cedars-sinai.edu)
- Integrated prediction of lesion-specific ischaemia from quantitative coronary CT angiography using machine learning: a multicentre study. (cedars-sinai.edu)
- Quantitative global plaque characteristics from coronary CT Angiography for the prediction of future cardiac death during 5 years of follow-up. (cedars-sinai.edu)
- Diagnostic Performance of Machine Learning-Derived Radiomics Signature of Pericoronary Adipose Tissue in Coronary Computed Tomography Angiography for Coronary Artery In-Stent Restenosis. (cdc.gov)
- Machine Learning Identifies New Predictors on Restenosis Risk after Coronary Artery Stenting in 10,004 Patients with Surveillance Angiography. (cdc.gov)
- Performance of machine learning-based coronary computed tomography angiography for selecting revascularization candidates. (cdc.gov)
Computed tomography2
- Epicardial fat volume (EFV) and coronary artery calcium (CAC) were quantified by noncontrast computed tomography (CT). (amegroups.org)
- Pericoronary adipose tissue computed tomography attenuation and high-risk plaque characteristics in acute coronary syndrome compared with stable coronary artery disease. (cedars-sinai.edu)
Percutaneous coronary int10
- Only patients with ST-segment elevation myocardial infarction (STEMI) receiving successful primary percutaneous coronary intervention (pPCI) and defined Δapelin-12 with apelin-12 elevation per cent 72 hours after pPCI compared with apelin-12 level immediately prior to pPCI were enrolled. (bmj.com)
- ST-elevation myocardial infarction (STEMI) following successful primary percutaneous coronary intervention (pPCI) is the leading cause of mortality and morbidity worldwide in major adverse coronary events (MACEs) due to mechanical complications, acute heart failure and cardiac shock after successful procedure. (bmj.com)
- Blood group non-O is not associated with long-term adverse outcomes in patients undergoing percutaneous coronary intervention. (nih.gov)
- Neurotensin and Adverse Cardiovascular Outcomes in Patients Undergoing Percutaneous Coronary Intervention. (nih.gov)
- Comparison of machine-learning models for the prediction of 1-year adverse outcomes of patients undergoing primary percutaneous coronary intervention for acute ST-elevation myocardial infarction. (cdc.gov)
- Using Artificial Intelligence in Predicting Ischemic Stroke Events After Percutaneous Coronary Intervention. (cdc.gov)
- Machine learning for prediction of bleeding in acute myocardial infarction patients after percutaneous coronary intervention. (cdc.gov)
- Multi-modal fusion model for predicting adverse cardiovascular outcome post percutaneous coronary intervention. (cdc.gov)
- A novel 6-metabolite signature for prediction of clinical outcomes in type 2 diabetic patients undergoing percutaneous coronary intervention. (cdc.gov)
- Prediction of 3-year all-cause and cardiovascular cause mortality in a prospective percutaneous coronary intervention registry: Machine learning model outperforms conventional clinical risk scores. (cdc.gov)
Calcification3
- The aim of this study was to evaluate whether EAT volume was associated with coronary artery calcification (CAC) in people living with diabetes, independently of confounding factors. (researchsquare.com)
- CCT imaging for CAD initially quantified coronary artery calcification, as it was readily detected on CT images, and quantified to generate a coronary artery calcium score (CACS) that represented a surrogate marker of the presence and extent of CAD. (bmj.com)
- Conclusion: PAT was associated with the presence and severity of coronary artery calcification in this cohort, but neither association varied by race/ethnicity. (johnshopkins.edu)
Epicardial adipose tissue thickness4
- Background: Increased epicardial adipose tissue thickness and plasma homocysteine levels are associated with Metabolic Syndrome (MS) and coronary artery disease. (erdogan.edu.tr)
- The aim of this study was to evaluate the relationship between MS and plasma homocysteine levels and epicardial adipose tissue thickness in subjects without epicardial coronary artery disease. (erdogan.edu.tr)
- All patients have been subjected to full hepatic profile, noninvasive scoring system such as Fibrosis-4 and non-alcoholic fatty liver disease fibrosis score and abdominal ultrasound for diagnosis of non-alcoholic fatty liver disease and trans-thoracic echocardiography for measurement of average epicardial adipose tissue thickness. (springeropen.com)
- High epicardial adipose tissue thickness may represent a marker of severity of non-alcoholic fatty liver disease as well as an independent predictor of coronary artery disease risk. (springeropen.com)
Acute coronary6
- Familial hypercholesterolemia (FH) is an autosomal dominant disorder characterized by elevated low-density lipoprotein cholesterol concentration and premature acute coronary syndrome (ACS). (go.jp)
- Although obesity is a well-established cardiovascular risk factor, some controversy has arisen with regard to its effect on hospital mortality in patients admitted for acute coronary syndrome. (hindawi.com)
- Clinical and anthropometric variables were analyzed in patients consecutively admitted for acute coronary syndrome to a university hospital between 2009 and 2010, and the correlation of those variables with hospital mortality was examined. (hindawi.com)
- There is something of a paradox in the relationship between body mass index and hospital mortality in patients with acute coronary syndrome in that the mortality rate decreases as body mass index increases. (hindawi.com)
- This situation, in which obesity seems to protect patients with acute coronary syndrome (ACS), has been called "the obesity paradox" and has been described in other facilities. (hindawi.com)
- Data Modeling Using Vital Sign Dynamics for In-hospital Mortality Classification in Patients with Acute Coronary Syndrome. (cdc.gov)
Inflammation11
- However, coronary artery disease risk is also driven by biological processes, such as inflammation, that are not fully reflected by severity of stenosis, myocardial ischaemia or by coronary plaque features. (bmj.com)
- New cardiac CT techniques can assess coronary artery inflammation by imaging perivascular fat, and this may represent an important step forward in identifying the 'residual risk' that is not detected by plaque or ischaemia imaging. (bmj.com)
- Coronary artery disease risk assessment that incorporates clinical factors, plaque characteristics and perivascular inflammation offers a more comprehensive individualised approach to quantify and stratify coronary artery disease risk, with potential healthcare benefits for prevention, diagnosis and treatment recommendations. (bmj.com)
- We assessed PCAT density, as a measure of pericoronary inflammation, in relationship to coronary plaque among people with HIV (PWH) and to a matched control population. (reprievetrial.org)
- Conclusion Among PWH in REPRIEVE, a large primary cardiovascular disease prevention cohort, increased PCAT density independently associated with prevalence and severity of coronary plaque, linking increased coronary inflammation to CAD in PWH. (reprievetrial.org)
- Background: The coronary adventitia has recently attracted attention as a source of inflammation because it harbors nutrient blood vessels, termed the vasa vasorum (VV). (tokushima-u.ac.jp)
- Conclusions: Lipid-rich coronary plaques are associated with adventitial VV and local inflammation in adjacent EAT in fresh cadavers. (tokushima-u.ac.jp)
- This study suggests that local inflammation of EAT is associated with coronary plaque progression via the VV. (tokushima-u.ac.jp)
- More recent studies suggest that inflammation in adipose tissue could be a key factor leading to these illnesses. (bu.edu)
- Finally, lipopolysaccharide administration induced a long-lasting expression of IL-1Ra in mouse WAT, suggesting that adipose tissue is an important source of IL-1Ra in both obesity and inflammation. (diabetesjournals.org)
- The main function of Interleukin (IL)-17 appears to be the regulation of local tissue inflammation via the coordinated expression of pro-inflammatory cytokines and chemokines. (biomedcentral.com)
Disease37
- The CAC score assesses the volume of coronary calcifications located in atherosclerotic plaques and provides a summary measure of atherosclerotic disease, reflecting the cumulative lifetime effect of risk factors and genetic and environmental factors [7]. (researchsquare.com)
- Recent studies have focused on the potential role of epicardial adipose tissue (EAT) in the development of coronary artery disease (CAD). (biomedcentral.com)
- Cardiac imaging is central to the diagnosis and risk stratification of coronary artery disease, beyond symptoms and clinical risk factors, by providing objective evidence of myocardial ischaemia and characterisation of coronary artery plaque. (bmj.com)
- Cardiac CT (CCT) imaging has transformed the detection, characterisation and stratification of coronary artery disease (CAD) risk in individuals. (bmj.com)
- The majority of patients with MS have subclinical or manifest coronary artery disease. (erdogan.edu.tr)
- Epicardial adipose tissue (EAT) is closely related to coronary artery disease (CAD). (amegroups.org)
- Coronary artery disease (CAD) is the major cause of mortality in Chinese residents and has become a serious threat to national health ( 1 ). (amegroups.org)
- Our study aimed to determine the association between non-alcoholic fatty liver and increased epicardial adipose tissue mass with coronary artery disease severity. (springeropen.com)
- One of the main concerns of the cardiology studies is how to prevent coronary artery disease development and how to estimate the risk of the disease before it becomes clinically symptomatic [ 1 ]. (springeropen.com)
- Risk factors for coronary artery disease (CAD) were not formally established until the initial findings of the Framingham Heart Study in the early 1960s. (medscape.com)
- Traditional versus nontraditional risk factors for coronary artery disease (CAD). (medscape.com)
- To examine the association between fat intake and the incidence of coronary heart disease in men of middle age and older. (bmj.com)
- After age and several coronary risk factors were controlled for significant positive associations were observed between intake of saturated fat and risk of coronary disease. (bmj.com)
- For men in the top versus the lowest fifth of saturated fat intake (median = 14.8% v 5.7% of energy) the multivariate relative risk for myocardial infarction was 1.22 (95% confidence interval 0.96 to 1.56) and for fatal coronary heart disease was 2.21 (1.38 to 3.54). (bmj.com)
- Positive associations between intake of cholesterol and risk of coronary heart disease were similarly attenuated after adjustment for fibre intake. (bmj.com)
- These data do not support the strong association between intake of saturated fat and risk of coronary heart disease suggested by international comparisons. (bmj.com)
- They are compatible, however, with the hypotheses that saturated fat and cholesterol intakes affect the risk of coronary heart disease as predicted by their effects on blood cholesterol concentration. (bmj.com)
- International comparisons 1 2 3 4 and laboratory data 5 suggest that diets high in saturated fat and cholesterol and low in polyunsaturated fat increase the risk of coronary heart disease. (bmj.com)
- These diets increase blood cholesterol concentration, 6 7 8 9 which is related to risk of coronary disease. (bmj.com)
- Radiation therapy to treat childhood cancer may damage adipose tissue, causing diabetes and coronary heart disease decades later. (rockefeller.edu)
- Cohen, a physician-scientist exploring obesity and metabolic disease, has conducted groundbreaking research on the complex inner workings of fat tissue. (rockefeller.edu)
- Many clinical studies suggest that an increase in EAT volume is associated with coronary artery disease. (go.jp)
- All patients admitted consecutively between 2009 and 2010 for ACS were included in the RENACI database of the Working Group on Ischemic Heart Disease and Coronary Care Units of the Spanish Cardiology Society. (hindawi.com)
- Although a recent joint society scientific statement (the American Association of Cardiovascular Pulmonary Rehabilitation, the American Heart Association, and the American College of Cardiology) suggests home-based cardiac rehab (CR) is appropriate for low- and moderate-risk patients, there are no paradigms to define such individuals with coronary heart disease. (journaltocs.ac.uk)
- We reviewed a decade of data from all patients with coronary heart disease enrolled in a single CR center (University of Michigan) to identify the prevalence of low-risk factors, which may inform on consideration for participation in alternative models of CR. (journaltocs.ac.uk)
- In this observational study, we provide a first paradigm of identifying factors among coronary heart disease patients that may be considered low-risk and likely high-gain for participation in alternative models of CR. (journaltocs.ac.uk)
- Background In patients with suspected coronary artery disease (CAD), myocardial perfusion is assessed under rest and pharmacological stress to identify ischemia. (unav.edu)
- Furthermore, inactivating variants in ANGPTL4 are associated with reduced risk of coronary artery disease in humans, suggesting that ANGPTL4 and related LPL modulators may be targets for modification of dyslipidemia-related atherosclerotic cardiovascular disease 8 , 9 . (nature.com)
- Body mass index, waist circumference, and risk of coronary heart disease: a prospective study among men and women. (scielosp.org)
- 1.5 - Relationship of dietary fat type to HDL functionality, composition and concentration, and association with coronary heart disease. (usda.gov)
- Coronary Heart Disease in the REasons for Geographic and Racial posure was sex-specific quartiles of waist circumference. (cdc.gov)
- Central adiposity and coronary heart disease (CHD) are influenced by indi- vidual and neighborhood characteristics, but it is unknown if the relation- ship between central obesity and development of CHD is influenced by Results these factors. (cdc.gov)
- Obesity is a well-established risk factor for coronary heart disease ence the relationship between waist circumference and CHD in (CHD) (1-4) and has been associated with higher rates of death at- race-sex subgroups by using data from the longitudinal cohort in tributable to cardiovascular disease (CVD) (5). (cdc.gov)
- Metabolic Syndrome (MS) and obesity, mainly visceral obesity, are associated with increased mortality due to Coronary Artery Disease (CAD). (biomedcentral.com)
- Can machine learning unravel unsuspected, clinically important factors predictive of long-term mortality in complex coronary artery disease? (cdc.gov)
- Using machine learning to aid treatment decision and risk assessment for severe three-vessel coronary artery disease. (cdc.gov)
- In patients with acute coronary disease, CRP level predicts mortality and cardiac complications. (medscape.com)
Arteries5
- Total body adiposity correlates with the amount of epicardial adipose tissue (EAT), a specific visceral fat accumulation around the myocardium in the proximity to the coronary arteries [ 2 ]. (biomedcentral.com)
- Recent evidence revealed that perivascular adipose tissue is involved in vascular homeostasis and pathophysiology of adjacent arteries by producing various adipokines. (go.jp)
- Epicardial adipose tissue (EAT) is located between the surface of the heart and the visceral layer of the pericardium and surrounds the coronary arteries. (go.jp)
- Where are coronary arteries and veins found? (healthtap.com)
- Uptake of AcAc LDL was not observed in the endothelia of arteries (including the coronaries and aorta), veins, or capillaries of the heart, testes, kidney, brain, adipose tissue, and duodenum. (rupress.org)
White adipos5
- In this study, we examined the expression pattern of IL-1Ra and showed that it is highly expressed not only in liver and spleen, but also in white adipose tissue (WAT), where it is upregulated in obesity. (diabetesjournals.org)
- The mRNA expression levels of peroxisome proliferator-activated receptor (PPAR)-γ and lipocalin-2 in white adipose tissue were, respectively, down- and up-regulated. (biomedcentral.com)
- Reduction of PPAR-γ expression and generation of a pro-inflammatory environment by increased lipocalin-2 expression in white adipose tissue may contribute to stress-induced glucose intolerance. (biomedcentral.com)
- This study aims to unveil biological markers that establish the molecular basis of stress-induced glucose intolerance, with a special emphasis on the visceral white adipose tissue (vWAT). (biomedcentral.com)
- Particularly well developed in humans is white adipose tissue (WAT), a major meta- bolic and secretory organ. (123dok.org)
Perivascular2
- Chaldakov developed a complex tripartite model of atherogenesis which involve smooth muscle cells, immune cells, and perivascular adipose tissue communicating through secreted factors (e.g. neurotrophins, adipokines, cytokines). (wikipedia.org)
- Conceptualize the protein secretory products of adipose tissue cells as adipokines, also focusing on perivascular adipose tissue. (wikipedia.org)
Inflammatory5
- Background Pericoronary adipose tissue (PCAT) may influence plaque development through inflammatory mechanisms. (reprievetrial.org)
- Methods and Results: Lesion characteristics in the left anterior descending coronary artery of 10 fresh cadaveric hearts were evaluated using integrated backscatter intravascular ultrasound (IB-IVUS), and the density of the VV and levels of inflammatory molecules from the adjacent EAT were measured for each of the assessed lesions. (tokushima-u.ac.jp)
- Initial studies of bariatric surgery patients by the Ruderman laboratory established (1) that they could be subdivided into insulin resistant (75%) and insulin sensitive (25%) subgroups and (2) that these subgroups were distinguished by differences in AMPK activity, oxidative stress and the expression of inflammatory, mitochondrial and other genes in their adipose tissue. (bu.edu)
- In summary, we demonstrated that WAT is one of the most important sources of IL-1Ra quantitatively, suggesting that this tissue could represent a novel target for anti-inflammatory treatment. (diabetesjournals.org)
- The overactivation of the sympathetic system and the promotion of a pro-inflammatory state in the adipose tissue [ 8 ] are common features of insulin resistance [ 9 - 12 ]. (biomedcentral.com)
Cardiovascular3
- Epicardial adipose tissue (EAT) has recently been proposed as one determinant contributing to the pathophysiology of cardiovascular complications [3-6]. (researchsquare.com)
- Major Adverse Cardiovascular Events in Coronary Type 2 Diabetic Patients: Identification of Associated Factors Using Electronic Health Records and Natural Language Processing. (cdc.gov)
- In the human body, the excess of adipose tissue is involved, as it potentializes the development of cardiovascular, osteomuscular, and neoplastic pathologies 2,3 . (bvsalud.org)
Thickness1
- Also, the epicardial adipose tissue mean thickness was found to be statistically significantly higher among those with significant coronary stenosis than those without [7.859 ± 0.691 mm versus 5.600 ± 0.386 mm]. (springeropen.com)
Severity2
- Hemodynamically significant CAD was defined by coronary stenosis severity ≥50% with reversible perfusion defects in the corresponding areas of SPECT/MPI. (amegroups.org)
- The aim of our work was to determine the association between non-alcoholic fatty liver and increased epicardial adipose tissue mass and its relation to severity of CAD. (springeropen.com)
Calcium2
- Coronary artery calcium (CAC) is considered a good marker of coronary risk [7]. (researchsquare.com)
- Methods In this baseline analysis of 727 participants of the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) Mechanistic Substudy, we related CT-derived PCAT density to presence and extent (Leaman score) of CAD, non-calcified plaque, coronary artery calcium (CAC), and vulnerable plaque (VP) features using multivariable logistic regression analyses. (reprievetrial.org)
Intra-abdominal2
- While much of the attention was directed to the importance of intra-abdominal adipose tissue, there were several new investigations about mediastinal and epicardial regions' visceral adiposity. (springeropen.com)
- Aging is associated with changes in body composition, revealed by reduction in lean mass, increase in fat mass and redistribution of these tissues in the body, with greater accumulation of intra-abdominal and intramuscular fat. (scielosp.org)
Endocrine3
- Adipose tissue serves not only as an energy store or a mechanical cushion, but also as an endocrine organ. (go.jp)
- The adipose tissue participates in numerous endocrine functions via the secretion of bioactive molecules, such as adipokines [ 10 ]. (plos.org)
- Recently, the endocrine activity of adipose tissue cells has been intensively studied. (123dok.org)
Mortality1
- Coronary artery diseases (CAD) have become a serious epidemic reason of morbidity and mortality. (springeropen.com)
Secretion1
- The association found between the amount of visceral fat and circulating levels of eotaxin on the one hand, and IMT on the other, could reinforce the hypothesis that IL-17, released by the visceral adipose tissue, induces eotaxin secretion via the smooth muscle cells present in the atheromatosus vessels. (biomedcentral.com)
Metabolic syndrome1
- Metabolic Syndrome Metabolic syndrome is characterized by a large waist circumference (due to excess abdominal adipose tissue), hypertension, abnormal fasting plasma glucose or insulin resistance, and dyslipidemia. (msdmanuals.com)
Adipokines1
- In effect, a wide range of exported secretory proteins, dubbed adipokines, have been identified as constituents of the adipose proteome (adipokinome). (123dok.org)
Plaque2
- Intravascular imaging, using ultrasound (IVUS) or optical coherence tomography, reveals that angiographic assessment of the coronary lumen grossly underestimates the presence, nature and extent of coronary artery plaque. (bmj.com)
- A coronary artery blockage of myocardial infarction (heart attack) occurs when an atherosclerotic plaque ruptures losing its fibrous cap and lipid cor. (healthtap.com)
Heart2
- Epicardial adipose tissue (EAT) has anatomic and functional proximity to the heart and is considered a novel diagnostic marker and therapeutic target in cardiometabolic diseases. (researchsquare.com)
- Epicardial adipose tissue (eat) which is vat (visceral adipose tissue) on the surface of the heart. (healthtap.com)
Cardiac1
- Paired EAT and SAT samples were collected from 82 patients undergoing elective cardiac surgery either for coronary artery bypass grafting (CAD group, N = 66) or valve surgery (NCAD group, N = 16). (biomedcentral.com)
Patients6
- It is our goal to establish an ARC focused on understanding the relationship between metabolic disorders and Adipose Tissue Biology by studying adipose tissues from insulin sensitive and insulin resistant patients obtained during and after Bariatric Surgery. (bu.edu)
- It would therefore be logical to expect obesity to have a lethal effect on patients who have suffered a coronary event. (hindawi.com)
- However, some studies have reported better short- and medium-term prognoses in overweight coronary patients [ 5 , 6 ]. (hindawi.com)
- However, we noticed that elevated STB appeared in unstable angina pectoris (UAP) patients with diffused coronary lesions. (journaltocs.ac.uk)
- The present study evaluated the efficacy of three medication regimes for the complete expulsion of retained intrauterine tissues in patients who underwent a miscarriage. (bvsalud.org)
- High CRP levels portend a worse prognosis in patients with acute coronary syndromes. (medscape.com)
Elevation myocardial1
- Identification of Coronary Culprit Lesion in ST Elevation Myocardial Infarction by Using Deep Learning. (cdc.gov)
Diabetes1
- Increased body mass index (BMI) alters the behavior of adipose tissue, which provides insulin resistance as well as resistance to type-2 diabetes, arterial hypertension, dyslipidemia, and proinflammatory and prothrombotic states, thereby favoring the onset of ischemic cardiopathy [ 3 ]. (hindawi.com)
Adiposity2
- in addition, loss of muscle tissue affects its validity as an indicator of adiposity in elderly people, regardless of changes in weight. (scielosp.org)
- At multiple regression, IMT was predicted, other than by age, by the amount of the visceral adiposity, expressed as visceral adipose tissue at ultrasonography, and by serum eotaxin. (biomedcentral.com)
Risk2
- As both progression of NAFLD and increasing epicardial adipose tissue (EAT) mass have the same risk factors, therefore these two conditions might be associated with each other [ 6 ]. (springeropen.com)
- An estimated 42.3% of coronary episodes in the Spanish population may be attributable to excess weight after adjusting for age, sex, and other risk factors [ 4 ]. (hindawi.com)
Obesity1
- Moreover, I3C exerts anti-obesity effects by reducing body weight and fat accumulation in epididymal adipose tissue in HFD-induced obese mice and thereby improves hyperglycemia and hyperinsulinemia [126]. (researchgate.net)
Pharmacology1
- Conceptualize studying adipose tissue-directed pharmacology as adipopharmacology. (wikipedia.org)
Liver1
- CRP is an acute-phase reactant synthesized by the liver in response to cytokines released by damaged tissue. (medscape.com)