• To investigate the potential predictive factors of the visual change achieved with accelerated epi-on and epi-off corneal collagen crosslinking (CXL) in keratoconus. (hindawi.com)
  • 2 ] demonstrated that the lower pretreatment corneal asphericity and corneal keratoconus index (CKI) were associated to a higher K max reduction after CXL [ 2 ]. (hindawi.com)
  • Aims To characterise posterior corneal surface features in patients with Down syndrome (DS) and to compare them with healthy and mild keratoconus corneas. (bmj.com)
  • Only patients with no previous ocular surgery, no corneal scars and no active ocular disease other than keratoconus were included. (bmj.com)
  • The Sirius System topographer (CSO, Firenze, Italy) was used in order to analyse posterior corneal surface keratometry, shape and keratoconus screening indices, posterior corneal aberrations, corneal volume and pachymetry. (bmj.com)
  • Additionally, posterior corneal surface in patients with DS shows similar characteristics to those found in mild keratoconus. (bmj.com)
  • Keratoconus is a corneal ectasia characterised by progressive corneal thinning that results in gradual corneal protrusion, irregular astigmatism and decreased vision. (bmj.com)
  • 9 In a recent work developed by our investigation team, 10 it was reported that patients with DS may present corneal morphological alterations similar to keratoconus in more than 70% of the cases, emphasising the importance of an early ophthalmic evaluation in this group of patients. (bmj.com)
  • Different studies report that posterior corneal surface data are useful in the diagnosis of keratoconus 11-13 and show a high discrimination capability in the early stages of the disease. (bmj.com)
  • 14 Additionally, posterior corneal surface characteristics correlate well with the degree of visual impairment in patients with keratoconus and might be used to determine the severity of the disease. (bmj.com)
  • Alhaji, H. Evaluation of Anterior and Posterior Corneal Higher Order Aberrations for the Detection of Keratoconus and Suspect Keratoconus. (preprints.org)
  • Aim: To investigate the application of anterior and posterior corneal higher order aberrations (HOAs) in detecting keratoconus (KC) and suspect keratoconus (SKC). (preprints.org)
  • Conclusion: Anterior and posterior corneal higher order aberrations can differentiate between keratoconus and normal eyes, with a high level of certainty. (preprints.org)
  • In suspect keratoconus disease however, only anterior corneal HOAs, and in particular coma-like aberrations, are of value. (preprints.org)
  • Corneal aberrometry may be of value in screening for keratoconus in populations with a high prevalence of the disease. (preprints.org)
  • To report a comparative prospective long-term functional analysis after Riboflavin UV A corneal cross-linking (CXL) in three different age groups of patients affected by progressive keratoconus (KC). (unicatt.it)
  • Clinical examination with the slit lamp revealed signs of keratoconus, with prominent corneal nerves in the left corneal stroma. (defeatkeratoconus.com)
  • asphericity asymmetry index (AAI), coma, spherical aberration, Kappa distance and the presence of a keratoconus suspect cornea. (ufpr.br)
  • To compare the rate of fractional change for multiple corneal tomographic factors in progressive keratoconus (KC). (biomedcentral.com)
  • Understanding this mechanism is key to managing these corneal irregularities seen in keratoconus. (defeatkeratoconus.com)
  • To evaluate the efficacy and safety of implantation of Ferrara-type intrastromal corneal ring segments (ICRS) for the refractive correction of paracentral keratoconus with non coincident topographic and coma axis (Duck phenotype). (confex.com)
  • Snellen uncorrected (UDVA) and corrected (CDVA) distance visual acuity, residual refractive error, topographic parameters and aberrometry (vertical coma) were recorded before and 6 months after ICRS implantation for keratoconus. (confex.com)
  • Intrastromal corneal ring segment implantation in eyes with paracentral keratoconus with non coincident topographic and coma axis provided good visual and refractive outcomes. (confex.com)
  • Conclusions Posterior corneal surface of patients with DS is steeper, more irregular and shows more higher order aberrations, as well as reduced volume and thinner pachymetry than patients with healthy corneas. (bmj.com)
  • Higher order aberrations (HOAs) of the eye are unable to be corrected by cylinder or spherical corrections and include spherical aberrations, coma and trefoil. (news-medical.net)
  • SCTK is a transepithelial, customized, multistepped approach that addresses corneal higher-order aberrations (HOAs). (crstodayeurope.com)
  • The rate of fractional change was higher for aberrometric parameters (anterior corneal higher-order aberrations root mean square and anterior coma) compared to pachymetric and keratometric parameters ( P values ranging from 1.4 × 10 −4 to 7.4 × 10 −10 , Mann-Whitney test, effect size ranging from 0.4-0.7). (biomedcentral.com)
  • Coma aberrations are caused when light rays from one edge of the pupil focuses before those from the opposing edge. (news-medical.net)
  • Classed as a third order aberration, trefoil has a more minor affect on image quality compared to an equal amount of coma. (news-medical.net)
  • The corneal deformation causes the ocular wavefront to be distorted (coma, negative spherical aberration, trefoil). (defeatkeratoconus.com)
  • Cases with previous history of ocular surgery, poor scans, corneal scars, severe dry eyes, post-excimer ectasia, pellucid marginal degeneration were excluded. (biomedcentral.com)
  • If marked ocular toxicity occurs and corneal injury is documented, obtain follow-up care with an ophthalmologist to ensure that healing is progressing. (medscape.com)
  • Unos de nuestros objetivos es obtener un producto celular capaz de regenerar la superficie ocular en casos de insuficiencia limbar total. (biocrucesbizkaia.org)
  • El daño severo del limbo esclero-corneal es una patología ocular que afecta a las células madre del limbo o a su nicho, pudiendo provocar ceguera. (biocrucesbizkaia.org)
  • La salud de la superficie ocular depende de la integridad del epitelio corneal. (biocrucesbizkaia.org)
  • En casos de defecto epitelial corneal persistente, que no responden a los tratamientos estándar, se han descrito diferentes métodos para mejorar el tropismo de la superficie ocular. (biocrucesbizkaia.org)
  • Para ello, realizamos resonancia magnética funcional en niños con dislexia y en niños con trastornos en la motilidad ocular, además de en un grupo control, para conocer los grupos neuronales que activan durante la lectura los diferentes grupos de niños. (biocrucesbizkaia.org)
  • Corneal HOAs caused by alterations in the posterior corneal surface are rare and cannot be corrected with SCTK or cataract surgery. (crstodayeurope.com)
  • It is thought that HOAs are responsible for individuals reporting complaints of glare, halos and reduction in contrast sensitivity following corneal refractive surgery. (news-medical.net)
  • SCTK can also be used to treat certain complications of refractive surgery, including a decentered treatment, postoperative corneal scars, an overly small optical zone, and interface problems during LASIK. (crstodayeurope.com)
  • Around three months after phacoemulsification, the refractive outcome was compared to the expected result and statistically associated to preoperative corneal variables. (ufpr.br)
  • He has extensive experience in corneal transplantation, laser refractive surgery, and cataract surgery. (yorkpedia.com)
  • We will look ahead at the latest techniques and technologies for corneal imaging, drug treatments/delivery, genetics, and surgery, especially transplantation and refractive surgery. (cybersight.org)
  • Each step of SCTK entails the use of tomography, topography, and aberrometry followed by the execution of a corneal wavefront-guided customized ablation pattern and wet PTK (ie, smoothing) with a tomographic quality check at the end. (crstodayeurope.com)
  • May cause chemical conjunctivitis and corneal damage. (pdf4pro.com)
  • In this phase of SCTK, corneal imaging is performed, and corneal wavefront-guided customized transepithelial ablation is executed with a pattern derived from the immediate preoperative corneal wavefront measurement. (crstodayeurope.com)
  • Exposure to high levels of the gas may cause corneal burns and cataracts. (cdc.gov)
  • It can cause corneal necrosis (tissue death) if it is not washed out quickly. (sorokalegal.com)
  • Based upon the corneal wavefront measurement of SA, Packer et al customized selection between a Tecnis aspheric monofocal IOL (Johnson & Johnson Vision) with an SA of -0.27 μm, an AcrySof IQ (Alcon) with an SA of -0.2 μm, and a SofPort AO (Bausch + Lomb) with an SA of 0 μm SA. (crstoday.com)
  • If corneal HOAs are still present or the surgeon is not satisfied with the outcome, a new corneal wavefront-guided customized ablation pattern, derived from the intraoperative corneal wavefront measurement, can be executed immediately, followed by wet PTK. (crstodayeurope.com)
  • The Sirius Scheimpfug (CSO, Italy) analyzer was used to measure HOAs of the anterior and posterior corneal surfaces. (preprints.org)
  • The main advantage of SCTK is that it treats corneal HOAs while removing a minimal amount of tissue. (crstodayeurope.com)
  • The procedure reshapes the corneal surface, and it prioritizes the elimination of HOAs over the correction of ametropia. (crstodayeurope.com)
  • If corneal HOAs are detected and correspond to alterations in the anterior corneal surface, they can be treated only by reshaping the cornea with customized excimer ablation (ie, SCTK) based on the corneal wavefront. (crstodayeurope.com)
  • Scleral lenses offer a unique way of addressing many issues raised in this case report such as corneal neovascularization and ectasia. (sclerallens.com)
  • Bilateral exotropia was noted with spared light and corneal reflexes and oculocephalic responses. (cdc.gov)
  • Corneal reflexes, pupillary responses to light and motor responses were the most reliably elicited. (ox.ac.uk)
  • In a recent study, normal eyes were randomly assigned to receive either an aberration-free IOL (enVista, Bausch +Lomb) or a negative spherical aberration IOL (Tecnis, -0.27 μm) without customized selection for preexisting corneal SA. (crstoday.com)
  • The conservative treatment modalities, such as spectacles and gas permeable rigid contact lenses, become insufficient for visual rehabilitation in the advanced stages of KC, and 10-20% of patients need corneal transplantation [ 3 ]. (hindawi.com)
  • Corneal tomography and wavefront data were acquired using Scheimpflug tomography (Pentacam, Oculus, Wetzlar, Germany). (biomedcentral.com)
  • Eye injuries can range from minor cuts and bruises to more serious injuries, such as detached retinas and corneal abrasions. (pacificattorneygroup.com)
  • Overall, it seems that the temptation to put these pods into their mouths is overwhelming, but an even greater risk may be burns to their eyes, especially corneal abrasions or other burns that could lead to vision loss. (medscape.com)
  • The asymmetry in the corneal deformation between the left and right eyes resides in the fact that the patient predominantly rubbed his left eye. (defeatkeratoconus.com)
  • Os parâmetros corneanos estudados foram: elevação máxima da esfera de referência BFTA (best-fit toric and aspheric sphere), AAI (asphericity asymmetry Index), coma, distância Kappa, aberração esférica e a presença de assimetrias corneanas leves como as presentes naqueles pacientes suspeitos para ceratocone e analisadas de acordo com o erro preditivo biométrico e o erro absoluto médio do resultado refrativo pós-operatório. (ufpr.br)
  • Corneal power asymmetry represented by coma increased the mean absolute error (MAE) (P = 0.022), impairing the precision of the intraocular lens power calculation. (ufpr.br)
  • Thus the coma, a corneal power asymmetry index, is an important corneal factor in the precision of the intraocular lens power calculation. (ufpr.br)
  • 1 2 Besides systemic pathologies, patients with DS can present several ophthalmic pathologies including corneal alterations. (bmj.com)
  • Owing to co-morbidities like cata- on the disc, overpass phenomenon, nicking racts and corneal pathologies in the elderly of blood vessels or nerve fibre layer defect population in developing countries, viewing was noted, the eye was declared to have fundus details is also a challenge. (who.int)
  • In the epi-off group, the CDVA change could be predicted from the preoperative minimum corneal thickness and magnitude of the vertical anterior corneal primary coma component ( = 0.001, R 2 = 0.446). (hindawi.com)
  • The tunnels were created with manual technique and a Ferrara intracorneal ring segment of 150º arc lenght with variable thickness was implanated on the flat axis covering the coma axis. (confex.com)
  • To investigate the status of corneal epithelial remodeling and changes in corneal aberration after femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) and FS-LASIK combined with corneal collagen cross-linking (FS-LASIK Xtra), and to analyze the relationship between corneal epithelial thickness (CET) and corneal aberration. (cjeo-journal.org)
  • The exam includes assessing the corneal reflex and manual palpation of the eyeball. (attorneysinmn.com)
  • Inter-observer agreement of the assessment of coma scales and brainstem signs in non-traumatic coma. (ox.ac.uk)
  • Patients with VS/UWS and MCS have severe brain damage who survive initial periods of coma (usually 1 to 3 weeks), can maintain brainstem functions, do not require mechanical respiratory support, and redevelop sleep-wake cycles, including prolonged periods of eye-opening, but have no (vegetative state) or intermittent but definite clinical evidence of consciousness (MCS). (medlink.com)
  • 8 The incidence of this corneal disorder in the general population is about 4-6 of 1000 but can vary between studies depending on two aspects: the ethnic group evaluated, in fact the pathogenesis of the disease is a combination of genetic and environmental factors, and the criteria used to establish the diagnosis. (bmj.com)
  • In phototherapeutic keratectomy (PTK), an excimer laser is used to treat a variety of corneal disorders such as surface irregularity, epithelial instability, and superficial opacity. (crstodayeurope.com)
  • The postoperative ΔCET after FS-LASIK Xtra is smaller than that after FS-LASIK, but the homogeneity of ΔCET in each region is similar between the two groups.The changes in corneal HOA after surgery are similar in both groups, and there is a certain association between the overall epithelial distribution and corneal aberration. (cjeo-journal.org)
  • Corneal biomechanical changes after collagen cross-linking from porcine eye inflation experiments, by S. Kling et al. (csic.es)
  • Coma is unresponsiveness from which the patient cannot be aroused and in which the patient's eyes remain closed. (msdmanuals.com)
  • A coma is a deep state of eyes-closed unconsciousness where a person is not able to respond to people or the environment around them. (life-source.org)
  • Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. (pdf4pro.com)
  • Inhalation: Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. (pdf4pro.com)
  • These include brain death (1968), the vegetative state/unresponsive wakefulness syndrome (1972), and, later, the minimally conscious state (2002), in addition to the previously recognized state of unarousable-unresponsive-unconsciousness known as coma. (medlink.com)
  • The diagnosis was confirmed at CDC through extraction of RNA from saliva and corneal epithelia, which was reverse transcribed with rabies-specific primers and amplified using the polymerase chain reaction (PCR) assay. (cdc.gov)
  • where he learned the art of advanced diagnosis and surgical/medical treatment of complicated corneal problems. (yorkpedia.com)
  • Patients in a coma might have brain stem responses, spontaneous breathing and/or non-purposeful motor responses. (life-source.org)
  • On HD 8, the patient became comatose and had no eye, verbal, and motor responses to noxious stimuli (Glasgow coma scale 3). (cdc.gov)
  • The aim of this study was to compare the rate of change in pachymetric, keratometric, and corneal wavefront-related parameters over a standardized change in time and base values (defined as the fractional rate of change later) in cases with progressive KC. (biomedcentral.com)
  • Some studies in patients of cataract age without corneal disease or a history of keratorefractive surgery have shown a wide range of corneal SAs, generally measured at the 6-mm optical zone (eg, +0.076 to +0.544 μm 14 ). (crstoday.com)
  • Characteristics of patients and treatment for bacterial keratitis in Corneal and external diseases department in Hospital do Servidor Público Estadual de São Paulo (HSPE-SP) from July 1997 to July 2018. (bjid.org.br)
  • At the end of this session, the audience will have an engaging assessment of the current corneal landscape and have an interactive session at the end to ask questions and have discussions on where we will be in the next 5-10 years to better treat our patients. (cybersight.org)
  • Healthy, unoperated corneas have a range of corneal SAs. (crstoday.com)