Orthologous to human COPB2 (COPI coat complex subunit beta 2). (nih.gov)
Violin plots show distribution of expression levels for Coatomer subunit delta (SMED30012276) in cells (dots) of each of the 12 neoblast clusters. (stowers.org)
Expression of Coatomer subunit delta (SMED30012276) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells. (stowers.org)
Violin plots show distribution of expression levels for Coatomer subunit delta (SMED30012276) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells. (stowers.org)
It has been recently proposed that binding of HIV type 1 Nef to the beta subunit of COPI coatomers participated in the Nef-induced CD4 downregulation through recognition of a novel diacidic motif found in the C-terminal disordered loop of Nef (V. Piguet, F. Gu, M. Foti, N. Demaurex, J. Gruenberg, J. L. Carpentier, and D. Trono, Cell 97:63-73, 1999). (hal.science)
Golgi4
Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. (wikipedia.org)
COPI vesicles transport molecules between different parts of the Golgi body and from the Golgi back to the rough ER. (jove.com)
COPI-coated vesicles are found associated with Golgi membranes at steady state, are involved in Golgi to endoplasmic reticulum (retrograde) vesicle transport, and possibly also in intra-Golgi transport. (umassmed.edu)
COPI coated vesicles are responsible for retrograde transport from the Golgi to the ER, while COPII coated vesicles are responsible for anterograde transport from the ER to the Golgi. (wikidoc.org)
Proteins5
Their formation is driven by the assembly of different classes of coat proteins, namely COPI, COPII, clathrin, or retromer complex. (jove.com)
The COPI and COPII coat proteins share similar structural features with Clathrin but differ in cargo sorting and vesicle formation mechanisms. (jove.com)
Béthune, J. and Wieland, F.T. (2018) Assembly of COPI and COPII Vesicular Coat Proteins on Membranes. (haw-hamburg.de)
A vesicle with a coat formed of the COPI coat complex proteins. (umassmed.edu)
Lee, C. , and Goldberg, J. (2010) Structure of coatomer cage proteins and the relationship among COPI, COPII, and clathrin vesicle coats . (cornell.edu)
COPII3
Based on the type of protein coats, these vesicles can be of three types: coat protein or COP-coated vesicles, COPI and COPII, and clathrin-coated vesicles. (jove.com)
COPI and COPII vesicles are composed of similar coat protein complexes called coatomers. (jove.com)
ArfGAP1 promotes COPI vesicle formation by facilitating coatomer polymerization. (nih.gov)
Vesicles9
Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. (wikipedia.org)
6. The structure of COPI vesicles and regulation of vesicle turnover. (nih.gov)
7. ARFGAP1 promotes the formation of COPI vesicles, suggesting function as a component of the coat. (nih.gov)
14. In vitro generation from the trans-Golgi network of coatomer-coated vesicles containing sialylated vesicular stomatitis virus-G protein. (nih.gov)
16. A major transmembrane protein of Golgi-derived COPI-coated vesicles involved in coatomer binding. (nih.gov)
Published by The Company of Biologists Ltd 2014 Coatomer Arf4 Scyl1 γ-COP ERGIC - 53 Tubulation Early secretory pathway Coatomer (COPI)-coated vesicles carry cargo between the stacks of the Golgi complex and in a retrograde direction from the cis. (biologists.com)
Inclusion of v-SNAREs into COPI vesicles could be mediated by direct interaction with the coat. (uni-luebeck.de)
In COPI vesicle-mediated retrograde transport involved in the biogenesis of COPI vesicles and vesicle coat recruitment. (nih.gov)
Then, CT migrates from the Golgi to the ER via coatomer I-coated vesicles. (medscape.com)
Specifically, they were interested in the protein alpha-COP , a component of a protein complex called COPI coatomer, which has been shown in prior studies to bind directly to SMN - the protein that is present in low levels in people with SMA. (smanewstoday.com)
Secretory pathway1
In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. (nih.gov)
Coat3
9. Lipid packing sensed by ArfGAP1 couples COPI coat disassembly to membrane bilayer curvature. (nih.gov)
17. Functional reconstitution of COPI coat assembly and disassembly using chemically defined components. (nih.gov)
The mechanisms by which v-SNAREs interact with COPI and COPII coat proteins seem to be different and may play a key role in determining specificity in vesicle budding. (uni-luebeck.de)
ArfGAP23
5. Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking. (nih.gov)
Increases coatomer-dependent GTPase-activating activity of ARFGAP2. (nih.gov)
Increases coatomer-dependent activity of ARFGAP2. (nih.gov)
ArfGAP11
2. ArfGAP1 activity and COPI vesicle biogenesis. (nih.gov)
Machinery1
11. Spatiotemporal dynamics of the COPI vesicle machinery. (nih.gov)
Alpha1
Another possibility is that "COPI coatomer function is impaired under conditions of low SMN, and by over-expressing alpha-COP, we are restoring some previously un-appreciated loss of COPI coatomer function," they added. (smanewstoday.com)
Transport1
Mittels siRNA-Silencing wurde außerdem die überwiegende Beteiligung von COPI am intrazellulären Transport von FVIII deutlich, dessen Herunterregulierung zu einer 78 prozentigen Reduktion der FVIII-Sekretion im Gegensatz zu 32 Prozent bei COPII führte. (uni-frankfurt.de)
Interaction1
We show here that in an mRNA independent manner, endogenous Nucleolin co-precipitates endogenous α-COP and ε-COP but not β-COP which may reflect an interaction with the so-called B-subcomplex rather a complete COPI heptamer. (nih.gov)
Components2
12. Hazara Nairovirus Requires COPI Components in both Arf1-Dependent and Arf1-Independent Stages of Its Replication Cycle. (nih.gov)
ARF-GAP acts catalytically to recruit COPI components. (uni-luebeck.de)