Conventional anticancer therapy. Medical search. Frequent questions

Although combination of immune therapy with some conventional cytotoxic chemotherapies can be envisioned, the important question of how to integrate these novel immunotherapy treatments with the current clinical strategy still remains. (medscape.com)
In addition, plasma could be combined with other treatments -such as immunotherapy- to boost its anticancer activity. (mdpi.com)
This information highlights the importance of antitumor immunity development after radiation therapy, and the potential added benefits of combined radiotherapy and immunotherapy. (frontiersin.org)
While hyperthermia alone is often not sufficient when treating cancer, it greatly improves other conventional modalities like radio-, chemo-, or immunotherapy. (dovepress.com)
Research into anti-cancer cures continues, with promising advancements in areas such as immunotherapy and gene therapies. (mindxmaster.com)
Individuals typically seek these therapies to supplement or replace conventional medical treatments, such as surgery, chemotherapy , immunotherapy , or radiation therapy . (medicalnewstoday.com)
These include antiangiogenic agents, immunotherapy, bacterial agents, viral oncolysis, targeting of cyclic-dependent kinases and tyrosine kinase receptors, antisense approaches, gene therapy and combination of various methods. (researchandmarkets.com)
Important methods of immunotherapy in cancer involve the use of cytokines, monoclonal antibodies, cancer vaccines and immunogene therapy. (researchandmarkets.com)
There are shared interests with Therapeutic Immune Regulation (TIR) in combinations of targeted or conventional therapy with immunotherapy to circumvent chemo drug resistance. (nih.gov)

12. Conventional chemotherapy and emerging targeted therapy for advanced adrenocortical carcinoma. (nih.gov)
Preliminary studies in humans show that IP(6) and inositol, the precursor molecule of IP(6), appear to enhance the anticancer effect of conventional chemotherapy, control cancer metastases, and improve quality of life. (oneradionetwork.com)
The mice they have been using are resistant to conventional chemotherapy. (disabled-world.com)
The best part of all of this is that should their research succeed in human trials - not only will chemotherapy become outdated, people with cancer will be able to receive this new form of therapy on an outpatient basis. (disabled-world.com)
In addition, such approach could help to overcome the dose-limiting off-target delivery of conventional chemotherapy, while even reducing the amount of administered drug. (nano-initiative-munich.de)
For chemotherapy treatment, the cannabinoids can also protect the brain cells from the neurotoxicity treatments, PEA, an endocannabinoid-like compound, can help protect the heart cells and CBD lessens the ulcers of radiation therapy. (projectcbd.org)
The majority of participants in this group had had either surgery, chemotherapy, or radiation therapy. (projectcbd.org)
The RIST treatment protocol has a multimodal metronomic therapy design combining molecular-targeted drugs (Rapamycin and Dasatinib) with chemotherapy backbone (Irinotecan and Temozolomide), which is currently verified in a phase II clinical trial (NCT01467986). (medsci.org)
This novel metronomic multimodal treatment protocol combines two molecular-targeted drugs, the mTOR-inhibitor Rapamycin and the multi-kinase inhibitor and immunosuppressant Dasatinib with conventional chemotherapy, consisting of the topoisomerase inhibitor irinotecan and the alkylating agent temozolomide. (medsci.org)
Thus, future clinical studies are needed to clarify the efficiency and toxicity of HSP90 inhibitors in the treatment of human AML, including studies where HSP90 inhibitors are combined with conventional chemotherapy. (eurekaselect.com)
The newer approaches to cancer treatment not only supplement the conventional chemotherapy and radiotherapy but also prevent damage to normal tissues and prevent drug resistance. (researchandmarkets.com)

The safe and effective delivery of anticancer agents to diseased tissues is one of the significant challenges in cancer therapy. (aus.edu)
Monoclonal antibodies can be used for the delivery of anticancer payloads such as radionucleotides, toxins and chemotherapeutic agents to the tumors. (researchandmarkets.com)

Determining whether pemetrexed exhibits anticancer effects on ESCC cells and understanding the underlying molecular mechanism are important for developing better chemotherapeutics for ESCC. (spandidos-publications.com)

Challenging the presiding view that chemotherapeutic agents were immunosuppressive, [ 9-14 ] we and others have shown that some chemotherapeutic agents could elicit an immunogenic form of tumor cell death that enhances anticancer immune responses and contributes to the clinical efficacy of these chemotherapies. (medscape.com)
Considering the contradictory data on their efficacy, we present an up-to-date summary of the pleiotropic effects of statins in cancer therapy and review their impact on different malignancies. (nih.gov)
Recently, anti-PD-1 antibodies that inhibit the functions of the PD-1 protein have demonstrated efficacy as anticancer drugs. (regenerativemedicine.net)
Identification and validation of combination therapies to maximize the efficacy of cancer treatments including rational combinations of conventional and targeted therapies with novel agents. (nih.gov)

The Cancer Cure Foundation does not recommend the abandonment of conventional therapies in favor of alternative therapies. (cancure.org)
The efficacies vary widely for alternative therapies, and scientific evidence may not support them. (medicalnewstoday.com)

In fact, the effectiveness of anticancer treatments and positive long-term prognosis for young women has increased. (uni-koeln.de)
The interaction between radiotherapy and the immune system is being explored to combine immune and radiation (including particles) treatments, which in many cases have a greater clinical effect than any of the therapies alone. (frontiersin.org)
Although conventional radiation is the most popular tool used in clinical settings, antitumor treatments using particle irradiation (i.e., protons or carbon ions) are becoming a useful alternative. (frontiersin.org)
After applying the combined treatment to breast cancer cells, they compared the results of the adjuvant therapy to those of the drug-only treatments. (naturalnews.com)
Cancer-associated malnutrition can lead to several negative consequences, including poor prognosis, reduced survival, increased therapy toxicity, reduced tolerance and compliance to treatments, and diminished response to antineoplastic drugs. (frontiersin.org)
While conventional medical treatments such as surgery remain the primary treatment approach, there has been growing interest in alternative treatments for melanoma. (medicalnewstoday.com)
Alternative treatments encompass diverse practices, from nutrition therapy and herbal medicine to mind-body techniques and more. (medicalnewstoday.com)
People may use CAM therapy to ease the side effects of cancer treatments, release stress and worries in relation to cancer, and take control over some of their care. (medicalnewstoday.com)
Before trying any alternative treatment, it is imperative to consult with a doctor, as certain CAM therapies may interfere with standard medical treatments for melanoma. (medicalnewstoday.com)
However, people should use herbal remedies cautiously, as their interactions with conventional treatments can be complex. (medicalnewstoday.com)
It complements conventional treatments by enhancing emotional resilience during the melanoma treatment journey. (medicalnewstoday.com)
CAM therapies may contribute to overall well-being, alleviate symptoms, and enhance quality of life, but they should not replace evidence-based conventional treatments. (medicalnewstoday.com)
Exosome therapies are now being explored in anti-cancer clinical trials and recent reports claim taxol-filled exosomes can be used to treat cancers in mice at 50-fold lower doses than conventional treatments, with the additional benefit that exosomes do not invoke an immune response [ 6 ]. (biomedcentral.com)
The majority of work has been done with medical cannabis rich in THC but more recent research highlights CBD for cancer as well as CBD helping conventional cancer treatments to work better. (projectcbd.org)
Cannabinoids may also enhance other treatments like photodynamics or ozone therapy . (projectcbd.org)
Your doctors have some good conventional treatments available to them (Zelboraf, Yervoy, possibly several other drugs). (cancer.org)

However, subsequent studies have shown that immune cells could also facilitate cancer progression by promoting the growth of tumor clones resistant to anticancer immunity. (medscape.com)
The concept of using ICD in antitumor therapy has started taking shape with the identification of some inducers mentioned above, which have a potential as anti-tumor vaccination strategies. (wikipedia.org)
Current scientific evidence indicates that conventional radiation therapy affects the tumor immunological profile in a particular manner, which in turn, might induce beneficial effects both at local and systemic (i.e., abscopal effects) levels. (frontiersin.org)
However, conventional photon radiotherapy can also modify the tumor phenotype and its environment, making the tumor more vulnerable to the immune system. (frontiersin.org)
1 From a physical perspective, the inverted depth-dose profile and the sharp dose fall-off after the Bragg peak offered by particle beams allow for a more precise localization of the radiation dosage to the tumor, as compared to conventional photons ( 12 ). (frontiersin.org)
Histologically- or cytologically-confirmed advanced solid malignancy based on archival tumor sample having progressed after treatment with at least one prior line of anticancer therapy. (nih.gov)
Modern anticancer therapies are based on the targeted delivery of active substances into the tumor cells, which reduces harmful effects in healthy tissues, allowing specific tumor destruction. (dovepress.com)
The tumor microenvironment is now recognized as a major factor that influences not only the response to conventional anti-cancer therapies but also helps define the potential for malignant progression and metastasis. (go.jp)
Based on these considerations, we developed the antiangiogenic hypoxic cell radiosensitizers, TX-1877, TX-1898 and the hypoxic cytotoxin TX-402 that inhibits the HIF-1α pathway We will also discuss our research involved with the development of other drugs to exploit tumor hypoxia, including a hypoxia-targeting boron carrier for boron neutron capture therapy (BNCT) and a p53 inhibiting radiosensitizer. (go.jp)
In addition, a sizeable fraction of many anticancer drugs fails to reach the tumor and instead distributes to normal tissues and organs, greatly diminishing therapeutic effectiveness and causing serious adverse reactions. (chop.edu)
Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy. (nih.gov)
Our results show that γPNAs targeting miR-210 cause significant delay in growth of a human tumor xenograft in mice compared to conventional PNAs. (nih.gov)
Expression of mannose receptor on the surface of antigen-presenting cells (APCs) opens another route for tumor therapy. (nano-initiative-munich.de)
Specific therapy depends on the location of the tumor. (medscape.com)
Encapsulating anticancer drugs in liposomes enables targeted drug delivery to tumor tissues and prevents damage to the normal surrounding tissues. (researchandmarkets.com)

The present review aims to summarize the immune-mediated effects of chemotherapeutic agents and their clinical relevance, the biological and clinical features of immune checkpoint blockers and finally, the preclinical and clinical rationale for novel therapeutic strategies combining anticancer agents and immune checkpoint blockers. (medscape.com)
The increasing numbers of promising new agents with novel mechanisms of action and the large number of institutions both capable of and interested in conducting Phase II clinical trials of cancer therapies in parallel with appropriate biological studies of the cellular target of the particular agent makes it desirable to expand NCI support in this area. (nih.gov)
The literature suggests that honey administered alone or as adjuvant therapy might be a potential natural antioxidant medicinal agent warranting further experimental and clinical research. (hindawi.com)
Pemetrexed is a clinical antifolate therapeutic agent with anticancer properties. (spandidos-publications.com)
Nonetheless, the clinical applications of RBAC can extend beyond cancer therapy. (researchgate.net)
However, the clinical utility of both established and experimental cytotoxic agents is often compromised by poor stability and a lack of solubility in conventional pharmaceutical vehicles used for drug administration. (chop.edu)
Nanoparticle-based delivery systems designed by researchers at the CCCR are tailored for different families of potent anticancer agents, including camptothecins, bioactive derivatives of staurosporine and podophyllotoxin, retinoids, taxanes, as well as new chemical entities, thus broadening the range of potential clinical applications. (chop.edu)
Clinical trials are ongoing for cancer therapy with benzimidazole drugs. (discoveries.news)
In addition, it appears that in some areas of the country, the pharmaceutical industry is assuming an increasing portion of clinical trial costs in order to bring promising new therapies to the market quickly. (nih.gov)
The large numbers of new anticancer agents of directly proceeding to phase III trials with- under development has challenged clinical out phase II data might be reasonable if there investigators seeking to design and imple- were limited numbers of new agents available ment clinical trials to improve outcome for for evaluation and if there were unlimited re- persons with cancer. (nih.gov)
Agents are being continually developed with a view to clinical translation, with several such therapies requiring measurement of very small doses. (nih.gov)

The remaining gaps in the knowledge on cancer diseases at the cellular and molecular levels are being filled on a daily basis as novel research methods and novel anticancer drugs emerge. (mdpi.com)
We also discuss the synergistic anti-cancer effects of statins when combined with other more conventional anti-cancer drugs to highlight areas of potential therapeutic development. (nih.gov)
ImClone licenses the disputed patent, which covers the use of monoclonal antibodies targeting epidermal growth factor receptor (EGFr) in combination with conventional anticancer drugs in cancer, from Sanofi-Aventis. (pharmatimes.com)
If used as an adjuvant alongside drug therapy, hibiscus extract would make it possible to use lower doses of drugs. (naturalnews.com)
Due to enhanced effectiveness of this targeted therapy, lower doses of anticancer drugs can be used, thus obviating or reducing untoward effects. (chop.edu)
However, issues with this treatment include the emergence of cancer cells resistant to targeted drugs, and side effects which differ from those for conventional anticancer drugs. (regenerativemedicine.net)
In the future, as well as analyzing the mechanism for the antitumor effect of anti-SIRPα antibodies in more detail, while carefully assessing the safety of the treatment, anti-SIRPα antibodies can potentially be developed as anticancer drugs. (regenerativemedicine.net)
My personal philosophy, based on having read hundreds and hundreds of scientific studies, is that there are many, literally hundreds, of drugs, foods, supplements and lifestyle choices that have anticancer effect. (cancer.org)
The market value of drug delivery technologies and the anticancer drugs are difficult to separate. (researchandmarkets.com)

Methotrexate-induced lung disease is a potentially dangerous lesion, which may occur acutely at any time during therapy and which has been reported at doses as low as 7.5 mg/week. (nih.gov)
2. Presence of overt leptomeningeal or active CNS metastases or primary tumour or CNS metastases that require local CNS-directed therapy (e.g., radiotherapy or surgery) or increasing doses of corticosteroids within the prior 2 weeks. (who.int)

With the availability of novel and more potent ATP competitive mTOR inhibitors, we expect to improve the RIST combination therapy. (medsci.org)

After the conventional intravenous administration, the therapeutic formulation faces some hurdles before reaching the target site. (nano-initiative-munich.de)

PtNPs are extensively studied because of their antimicrobial, antioxidant, and anticancer properties. (mdpi.com)

The diversity of nanoparticles (NPs) has allowed for the development of innovative technologies in drug formulation, targeted therapy, drug delivery, and diagnostics. (dovepress.com)
Numerous approaches to manufacture functional nanomaterials for anticancer therapy have been proposed and using nanoparticles as vehicles which carry both a targeting component and a specific drug one can improve the delivery of diverse agents into cells and tissues. (dovepress.com)
In regard to cancer therapy, magnetoelectric nanoparticles (MENs) have proven to be in a class of its own when compared to any other nanoparticle type. (aip.org)
Like conventional magnetic nanoparticles, they can be used for externally controlled drug delivery via application of a magnetic field gradient and image-guided delivery. (aip.org)

It is usually given in combination with other anticancer agents, most frequently with cisplatin, vinblastine, etoposide, adriamycin or dacarbazine. (nih.gov)

Researchers want to find new therapies to improve outcomes for people with these cancers. (nih.gov)
Bleomycin is a cystotoxic antibiotic that is used as an anticancer agent in the therapy of testicular and germ cell cancers, Hodgkin disease, lymphomas and tumors of the head and neck. (nih.gov)
A 2018 review also found that several common herbs, such as curcumin , ginger , garlic , clove , rosemary , saffron , and capsaicin , may have anticancer properties that inhibit skin cancers. (medicalnewstoday.com)
Despite significant advances in cancer treatment, conventional drug therapies for various cancers have many side effects. (biotechrep.ir)

Bleomycin is generally cytotoxic, and the minor serum enzyme elevations that occur during therapy are likely due to a direct toxic effect on hepatocytes. (nih.gov)
However, resources are constrained distinctive toxicity profiles compared with and there are a multitude of new agents conventional cytotoxic agents. (nih.gov)

Measurable disease per RECIST 1.1 (i.e., at least 1measurable lesion greater than or equal to 20 mm by conventional techniques or greater than or equal to 10 mm by spiral CT scan or MRI), with the last imaging performed within 28 days before C1D1, and documented disease progression during or after their most recent line of anticancer therapy. (nih.gov)

ICD is induced by some cytostatic agents such as anthracyclines, oxaliplatin and bortezomib, or radiotherapy and photodynamic therapy (PDT). (wikipedia.org)

a doctor who treats cancer with radiation therapy. (cancer.org)
The major modalities of therapy are Surgery (for local and local-regional disease) Radiation. (msdmanuals.com)

The team also noted in the study that using hibiscus extract as an adjuvant can increase the effectiveness of conventional drug therapy for cancer. (naturalnews.com)
In recent years, attention has been drawn by the effectiveness of treatment that targets specific proteins that express on both cancer cells and healthy cells including immune system cells (targeted therapy). (regenerativemedicine.net)

Therapy with bleomycin in combination with other agents is often associated with mild-to-moderate serum enzyme elevations, but is a rare cause of clinically apparent liver injury. (nih.gov)
and mebendazole in combination with other antiprotozoal agents including albendazole for neoplasm therapy is in Phase 2 (NCT02366884). (discoveries.news)
These include the use of microparticles as carriers of anticancer agents. (researchandmarkets.com)

Enhanced strength, durability, flexibility, performance, and inimitable physical properties associated with these materials has been exploited in a multitude of industries and treatment modalities including detection of tumors, targeted drug delivery, and prognostic visual monitoring of therapy. (nih.gov)

To date, research on RBAC has predominantly focused on its immunomodulatory action and application as a complementary therapy for cancer. (researchgate.net)

The Cancer Institute had a long interest in Pneumocystis pneumonia because of its appearance in cancer patients undergoing vigorous anti-cancer therapy, particularly patients with acute leukemia. (nih.gov)

5. Molecular markers and targeted therapies for adrenocortical carcinoma. (nih.gov)
The present study aimed to understand whether pemetrexed is able to exert anticancer effects on ESCC cells, and to determine the underlying molecular mechanism. (spandidos-publications.com)
The understanding of the organisation, structure and function of SAC components is essential for the molecular understanding of the process and to identify and evaluate new targets for cancer drug therapy. (eurekaselect.com)
Innovative cancer therapies are based on current concepts of the molecular biology of cancer. (researchandmarkets.com)

TNBC is the only major type of breast cancer without specific targeted therapy for improving patient outcomes. (oncotarget.com)

However, there is an affinity for some researchers to fire out a coherent proposition that usage of honey as a natural product supplement is well intentioned for reflection as a therapy or adjuvant antioxidant therapy in current medicine [ 9 , 10 ]. (hindawi.com)

Adjuvant therapy triggered higher amounts of oxidative stress on cancer cells. (naturalnews.com)

Moreover, there is also a very common concept of developing compounds with multiple functionalities-from combining diagnostics with therapy (theranostics) to specific targeting, and photodynamic therapy to immunogenic cell death induction. (mdpi.com)

The use of ICD inducers alone or in combination with other anticancer therapies (targeted therapies, immunotherapies) has been effective in mouse models of cancer and is being tested in the clinic. (wikipedia.org)
One is a specialized combination of nutrients used as a targeted cancer therapy, depending on the individual needs of the patient. (cancure.org)
More than three quarter's of Erbitux' use is as a combination therapy. (pharmatimes.com)
Applications that focus on the effects on the combination therapy on key oncogenic signaling processes and applications that focus on the immune-mediated response to targeted or conventional therapy may be reviewed in MCTC. (nih.gov)

Despite intensive therapy the prognosis of patients with high-risk relapsed or refractory neuroblastoma (rNB) comprising up about 60% of cases remains dismal [ 2 , 7 ]. (medsci.org)

In addition the beneficial uses of NPs in drug delivery, cancer treatment, and gene therapy may cause unintentional human exposure. (nih.gov)
Nanocarrier formulations for APC-targeting can be loaded with nucleic acids ('gene-therapy') coding for specific genes or an RNA-fragment mixture. (nano-initiative-munich.de)
Small interfering RNAs (siRNAs) can be targeted to tumors and one example is the suppression of H-ras gene expression indicating the potential for application in therapy of ovarian cancer. (researchandmarkets.com)
Cancer gene therapy is a sophisticated form of drug delivery for cancer. (researchandmarkets.com)

An editorial presenting the Trojan Horse Therapy research being done in Australia related to Cancer. (disabled-world.com)
Research has also showed the anticancer effects of some of the terpenes that would be present in a full-plant extract. (projectcbd.org)
The purpose of this meeting, the third in a series of four, was to elicit the views of health care providers, representatives of the pharmaceutical industry, and consumers regarding the impact of managed care reimbursement policies on translational research, which takes new therapies from the bench to the bedside. (nih.gov)

You should exercise caution before using any cancer treatment, whether conventional or alternative. (cancure.org)
Psychological counseling, support groups and even psychotherapy make up a critically important aspect of therapy in the world's most successful cancer treatment centers. (cancure.org)
Targeted therapy is a method owing to its limited side effect profile, particularly in cancer treatment. (dovepress.com)
G.lucidum seemed to be well tolerated when given with conventional cancer treatment. (cancerresearchuk.org)

There are additional therapies which we are adding on a second page that are not used as widely to treat cancer. (cancure.org)

Ginger ( Zingiber officinale Roscoe ) is another spice that may contain anticancer properties. (medicalnewstoday.com)

In addition, participants must have no other standard of care therapies that are deemed appropriate for the treatment of their malignancy. (nih.gov)
Too many other patients I've seen have eschewed conventional medicine so long that their poor performance status precludes standard therapies that would have been effective had they pursued them as something other than a final act of desperation. (medscape.com)

This effect is used in antitumor therapy. (wikipedia.org)

Every therapy may have potential side effects and should not be used without consulting a health-care practitioner, especially if you are already using another form of therapy, or if you are pregnant or nursing. (cancure.org)
Demarcation of its uses in current professional medicine as a potential therapy is entirely underutilized. (hindawi.com)
There is potential key solution to this problem: cryopreservation of ovarian tissue before cancer therapy with re-implantation after convalescence. (uni-koeln.de)
In addition, they also tested the adjuvant potential of hibiscus extract alongside drug therapy. (naturalnews.com)

Conclusions Described protocol of conventional cryopreservation of ovarian tissue can be used for treatment of patients with ovarian insufficiency. (uni-koeln.de)

This therapy is usually used in conjunction with the proteolytic enzymes, a broad-spectrum nutritional program, and a diet calling for fresh fruits and vegetables, whole grains, and the elimination of meat and dairy products for the duration of treatment. (cancure.org)
This makes drug therapy nonviable for long-term treatment. (naturalnews.com)
Cachexia cannot be fully reversed by a conventional nutritional support, but it is important to establish a continuous treatment schedule based on the implementation of nutrition, food supplements, drug therapy, exercise, and psychological counseling. (frontiersin.org)
The Mechanisms of Cancer Therapeutics C study section focuses on investigating the mechanisms-of-action of cancer therapies across drug classes in the treatment of human cancer. (nih.gov)

For the latter, he used conventional antisyphilitic therapy (mercury and arsenic) but preceded it with intravenous injections of insulin to induce hypoglycemia. (iptq.com)

In addition, this activation of the immune system could lead to a long-lasting anticancer response, often described as cancer vaccination and relapse prevention with professional APCs. (nano-initiative-munich.de)

Anatomy5

Organisms4

Diseases13

Chemicals and Drugs37

Analytical, Diagnostic and Therapeutic Techniques and Equipment25

Phenomena and Processes27

Disciplines and Occupations3

Technology, Industry, Agriculture1

Information Science1

Health Care2

Immunotherapy9

Chemotherapy11

Delivery of anticancer2

Exhibits anticancer1

Efficacy4

Alternative therapies2

Treatments16

Tumor15

Clinical11

Drugs9

Doses2

Inhibitors1

Therapeutic1

Antimicrobial1

Nanoparticles4

Cisplatin1

Cancers4

Cytotoxic2

Measurable1

Radiotherapy1

Radiation2

Effectiveness2

Agents3

Modalities1

Immunomodulatory1

Anti-cancer1

Molecular4

Outcomes1

Antioxidant1

Adjuvant therapy1

Photodynamic therapy1

Combination4

Prognosis1

Gene4

Research3

Cancer treatment4

Widely1

Properties1

Standard2

Effect1

Potential4

Ovarian1

Treatment4

Intravenous1

Addition1