Contribute stress inducer. Medical search. Frequent questions

However, oxidative stress has emerged as a key player in the development and the progression of liver cirrhosis [ 4 ] which is known to be a precursor of HCC. (hindawi.com)
Both hepatitis B virus (HBV) and hepatitis C virus (HCV) appear to be particularly more potent in inducing oxidative stress, suggesting unique mechanisms that are activated by these viral infections. (hindawi.com)
Oxidative stress is a prominent pathway for the health effects associated with fine particulate matter (PM2.5) exposure. (bvsalud.org)
Oxidative potential (OP) of PM has been associated to several health endpoints, but studies on its impact on biomarkers of oxidative stress remains insufficient. (bvsalud.org)
Autophagy may represent a mechanism of resistance to oxidative stress induced by chemotherapeutic drugs and may potentiate cancer cell survival to hypoxia and nutrient starvation due to the frequently defective tumor vascularization. (nature.com)
Pterostilbene alleviated neuroinflammation by suppressing oxidative stress and carbonyl stress damage, astrocyte and microglia activation, and dopaminergic neuronal loss. (qualitycounts.com)
Living organisms are frequently exposed to oxidative stress and toxic insults, like radiation, UV light, air pollution, toxins and others. (springer.com)
Oxidative stress generated during such stressful conditions may damage DNA and proteins, and as a consequence the cellular processes are disturbed. (springer.com)
Single cells and organisms may adapt to harmful oxidative stress conditions, through stress-activated factors. (springer.com)
However, the role of C1QBP in metabolism, oxidative stress, and apoptosis of renal cell carcinoma (RCC) cells have not yet been explored. (medsci.org)
Blood induced widespread microglial transcriptional changes, including changes involving oxidative stress and neurodegenerative genes. (nature.com)
Pathogenic activation of microglia contributes to oxidative stress, inflammation and neurodegeneration in both Alzheimer's disease (AD) and multiple sclerosis (MS) 6 . (nature.com)
To discover the molecular programs controlling microglial and macrophage polarization by blood proteins, we developed an unbiased blood-innate immunity multiomic and genetic loss-of-function pipeline consisting of deep sequencing of blood-induced transcriptomes, functional single-cell and oxidative stress transcriptomics, global phosphoproteomics and integration with innate immune signatures from AD and MS models (Extended Data Fig. 1 ). (nature.com)
I reviewed the overwhelming evidence suggesting that glyphosate is associated with increased risk of cancer, particularly non-Hodgkin's lymphoma, and many other effects, including gut dysbiosis, which in turn drives many chronic diseases, hormone imbalance, impaired fertility, reduced detox capacity, nutrient deficiency, and oxidative stress to name a few. (things4myspace.com)
TCDD for every step of the mechanism described for 2,3,7,8-TCDD carcinogenesis in humans including receptor binding, gene expression, protein activity changes, cellular replication, oxidative stress, promotion in initiation-promotion studies and complete carcinogenesis in laboratory animals. (who.int)

This study highlights the potent antioxidant properties of TD which contribute to its therapeutic effect in AFB 1 -induced HCC in rats. (hindawi.com)
Chronic infections are potent inducers of depression, and for some patients, infection testing may be recommended. (nordicclinic.se)

These are glucose-and lipo-toxicity, ER stress, pro-inflammatory cytokines, dysfunctions in autophagy, and β cells dedifferentiation. (lu.se)
When exposing the C3-knockout INS-1 cells to β cells autophagy inducers (palmitate and IAPP), we observed significantly increased cell death caused by autophagy insufficiency. (lu.se)

Group 2 innate lymphoid cells (ILC2s) adapt to tissue physiology and contribute to immunity, inflammatory pathology and metabolism. (elifesciences.org)
This important study describes the protective role of group 2 innate lymphoid cells (ILC2s) in tissue physiology and contributes to immunity, inflammatory pathology, and metabolism in maintaining homeostasis during pregnancy. (elifesciences.org)
Several internships confirmed my interest for plant-microbe interactions and led me to work on immunity induced by plant resistance inducers during my doctoral thesis. (plantae.org)

Despite extensive efforts, soybean yield improvement is facing severe challenges and suffers with yield loss due to a range of biotic and abiotic stresses. (frontiersin.org)
My PhD project focused on the defense mechanisms triggered by acibenzolar-s-methyl in apple against the fire blight bacterium Erwinia amylovora , as well as its combined impact to an abiotic stress, heat, on apple defenses. (plantae.org)

In this study, a set of Saccharomyces cerevisiae genes found, through genome-wide screenings, to confer resistance to the simultaneous presence of different relevant stresses were identified as required for maximal fermentation performance under industrial conditions. (biomedcentral.com)
and eleven genes conferring simultaneous resistance to stresses relevant during lignocellulosic fermentations. (biomedcentral.com)
A cluster of stress-responsive genes was upregulated via activation of the stress-resistance transcription factor Msn4, which indicated the stress effect of surplus iron on yeast metabolism. (molcells.org)
[ 10 ] Multiple biofilm-specific mechanisms are operated simultaneously in a reversible and transient manner contributing to the high levels of antibiotic resistance of biofilms, and these are distinct from the well-characterized intrinsic resistance mechanisms (e.g., expression of antibiotic-degrading enzymes, inducible decrease in antibiotic influx, inducible increase in antibiotic efflux and alteration in antibiotic target sites) employed by planktonic cells. (medscape.com)
Cells adapt to this environmental stress, so that after repeated periods of hypoxia, selection for resistance to hypoxia induced apoptosis occurs. (bmj.com)

Blood vessels produce beneficial phase 2 enzymes that help protect cells from carcinogens in response to shear stress, but in the joints high shear stress increases cyclooxygenase 2 (COX-2) enzyme levels, resulting in pain, inflammation and suppression of phase 2 enzymes, and the eventual death of cartilage cells known as chondrocytes. (lifeextension.com)
The phase 2 inducers seemed to counteract the effects of that stress by inhibiting the expression of COX-2 enzyme. (lifeextension.com)
From the 29 quantifications below 2.5 mg/L, 27 corresponded to lamotrigine+enzyme inducers therapies. (bvs.br)

The expression of photosynthesis and chlorophyll synthesis related genes were significantly reduced under both types of stresses, which limit the metabolic processes and thus help prolong survival under extreme conditions. (frontiersin.org)
This dual effect suggested that surplus iron might participate in a more complex metabolic network, in addition to serving as a stress inducer. (molcells.org)
Although iron overload can contribute to obesity-associated metabolic deterioration, the subcellular localization and accumulation of iron in adipose tissue macrophages is largely unknown. (biomed.news)
Although, the disease appears as a locoregional infection, the periodontal pathogens, in addition their metabolic products and systemic mediators, receive access to the bloodstream, thereby contributing to the development of systemic disorders. (encyclopedia.pub)

Of note, an increased carbohydrate uptake and/or induction of death receptors of cancer cells was exploited to develop glycoconjugates that potentially induce cellular stress, ROS and apoptosis. (degruyter.com)

bAGPs may therefore contribute to the expansion of pathogenic Stx-producing E. coli . (cdc.gov)

therefore, it is imperative to assess the expression of genes involved in response to flood and drought stress. (frontiersin.org)
These genes comprise 289 Transcription Factors (TFs) representing Basic Helix-loop Helix (bHLH), Ethylene Response Factors (ERFs), myeloblastosis (MYB), No apical meristem (NAC), and WRKY amino acid motif (WRKY) type major families known to be involved in the mechanism of stress tolerance. (frontiersin.org)
However, cell wall synthesis related genes were up-regulated under drought stress and down-regulated under flooding stress. (frontiersin.org)
The changes in expression of genes involved in regulating the flux of cell wall precursors and starch/sugar content can serve as an adaptive mechanism for soybean survival under stress conditions. (frontiersin.org)
Five genes, Erg2 , Prs3 , Rav1 , Rpb4 and Vma8 , were found to contribute to the maintenance of cell viability in wheat straw hydrolysate and/or the maximal fermentation rate of this substrate. (biomedcentral.com)
The identified genes stand as preferential targets for genetic engineering manipulation in order to generate more robust industrial strains, able to cope with the most significant fermentation stresses and, thus, to increase ethanol production rate and final ethanol titers. (biomedcentral.com)
Placentas exhibit signs of adaptation to stress, including larger maternal blood spaces and increased expression of nutrient transporter genes. (elifesciences.org)

Our results demonstrate that tumor growth, peritoneal dissemination and peritoneum or organ metastasis implanted MKN45 cells were significantly decreased in shAhR and Biseugenol-treated mice and that endoplasmic reticulum (ER) stress was caused. (oncotarget.com)

Boosting the immune system - do you know that about 80 to 90 percent of stress is related to disease? (neo-bux.info)
The cortisol is the hormone released every time a person is stressed, it will hurt the white blood cells which are responsible in the protection of the immune system. (neo-bux.info)
Regarding the immune system, ELF-EMF exposure contributes to a general activation of macrophages, resulting in changes of autoimmunity and several immunological reactions, such as increased reactive oxygen species-formation, enhanced phagocytic activity and increased production of chemokines. (maxwellmagneticmeds.co.za)

Vitamin B6 also contributes to the regulation of hormonal activity - it aids in the production of the hormones serotonin and melatonin, both of which are important to sound, restful sleep, and also to mood. (activeshop.lv)
L-theanine can positively impact the key neurotransmitters (brain chemical messengers) involved with stress, sleep, mood, focus, and memory. (activeshop.lv)
Physical activity also releases endorphins into your bloodstream, which is a good mood inducer. (psychreg.org)

These authors contributed equally to this work. (mdpi.com)

Furthermore, DS patients with PD presented high levels of 5-LO expression, suggesting the presence of leukotriene B4 (LTB4) in PD, thus demonstrating that the changes in NE function due to the elevation of inflammatory mediators contribute to PD. (bvsalud.org)

Since the HBP utilizes major macromolecules such as nucleotides, amino acids, carbohydrates, and lipids to produce UDP-GlcNAc, cells may use it as a 'sensor' of energy availability that influences a large number of functional targets that contribute to cancer phenotypes (Fig. 2 ). (biomedcentral.com)
Biofilms contain a small reversible subpopulation of so-called persister cells that adopt a slow- or nongrowing lifestyle through the emergence of small colony variants and are highly tolerant to extracellular stresses, such as antibiotic treatment. (medscape.com)
Shear stress is generated when liquids move across surfaces, which in this case are the cells lining the blood vessels and the joints. (lifeextension.com)
After 24 hours, the researchers subjected the cells to a stress test designed to mimic the effects of exercise, which would normally produce an increase in COX-2. (lifeextension.com)

Transcript profiles involved in the starch and sugar metabolism pathways were also affected under both stress conditions. (frontiersin.org)
Magnesium contributes to normal psychological functions, nervous system function, energy metabolism and electrolyte balance. (activeshop.lv)

Alterations in nutrient uptake homeostasis affect cellular energetics inducing cellular stress [ 1 ]. (biomedcentral.com)

Lemon Balm ( Melissa officinalis ) is a herb that has traditionally been used for a variety of cognitive purposes, most of which are centered around improving cognition and reducing stress and anxiety. (activeshop.lv)
Past trauma can also stoke anxiety in an individual, as can the most common anxiety inducer of them all: stress. (nurx.com)
Nevertheless, there are times when circumstances can inordinately increase stress levels, resulting in higher anxiety levels in the process. (nurx.com)
Cathy's clinical experience spans 20 years both as a private practitioner, and with several well-regarded mental health agencies throughout Southern California, where she serves diverse urban populations, providing psychotherapy for a broad range of clinical issues, including depression, anxiety, stress management, abuse, and trauma. (buzzsprout.com)
It has been identified that the prolonged stress to which workers in sewing cooperatives are subjected to in Mexico City, mostly women (81.2%), lead to the presence of physical and mental suffering, such as: anxiety, depression, cardiocirculatory diseases, digestive diseases, psychosomatic diseases and sleep disorders (1) . (bvsalud.org)

Exposure to stress is a part of life that generates a host of different responses, some of them akin to signs of illness without constituting or resulting in disease. (wikipedia.org)
One or several prior stress-inducing factors should be identified and the exposure must have lasted for 6 months or longer. (wikipedia.org)
Stress also contributes to depression, by increasing proinflammatory cytokines in circulation at exposure to stressful situations. (nordicclinic.se)

Mechanisms that contribute to those abilities involve biochemical, physiologic, or psychologic changes and can be expressed behaviorally as homeostatic processes of adjusting to altered environmental conditions. (nationalacademies.org)
The success of lignocellulosic biomass and VHG fermentations is necessarily dependent on the ability of the used yeast strains to cope with the different stresses imposed during these processes. (biomedcentral.com)

In the case of obesity, proinflammatory cytokines are formed in our adipose tissue which can contribute to depression. (nordicclinic.se)

It has been suggested that endogenous factors might contribute to the rapid progression of periodontal breakdown such as inappropriate regulation of enzymes, lipid mediators, collagen biosynthesis or T cell immunodeficiency. (bvsalud.org)

The distinction between benign and maladaptive responses to stress is not necessarily evident since there is no sharp line separating the two entities. (wikipedia.org)
It is considered vital to differentiate between exhaustion disorder and other responses to elevated or severe stress such as adjustment disorder, acute stress disorder and PTSD. (wikipedia.org)

When you think of massage therapy, the common things that comes to your mind would be stress relief and relaxation. (neo-bux.info)
According to studies, vitamin D deficiency is also a common contributing factor in depression. (nordicclinic.se)

The ability to avoid, escape from, or control pain and other inducers of stress and distress is critical to the survival and well-being of many animals (Phillips and Sechzer, 1989). (nationalacademies.org)

These findings contribute to our understanding of the global response of yeast to the fluctuating availability of iron in the environment. (molcells.org)

A prolonged period of elevated stress can lead to exhaustion, sleep disorders and a decline in cognitive abilities. (wikipedia.org)
Natural herbal extraxts Valerian and Lemon Balm are known in folk medicine as calming herbs for stress and sleep disorders. (activeshop.lv)

As is the case with other natural reactions, such as pain or stress, a threat triggering the limbic system is a normal and important part of everyday life. (nurx.com)

Niacin, another B vitamin which occurs in two forms (nicotinic acid and nicotinamide), also contributes to the maintenance of DNA integrity due to several important roles. (cambridge.org)
In the specific case of consumption of alcoholic beverages, it is emphasized that it often occurs to reduce stress and to provide relaxation, especially in situations of leisure and entertainment (4) . (bvsalud.org)

The symptoms of exhaustion disorder are numerous and include fatigue, reduced stress tolerance and various physical symptoms. (wikipedia.org)
The mechanism that overcomes drought stress in plants is facilitated by drought avoidance, drought tolerance, drought escape, and drought recovery ( Cruz De Carvalho, 2008 ). (frontiersin.org)

These moments are good checkpoints for you to assess if your routines are still healthy, if what you're doing still contributes to your overall happiness, and if you are taking care of yourself in a holistic manner. (psychreg.org)

Adaptor proteins, such as the sequestosome 1/p62-like receptors, which directly bind to cargos, contribute to specific molecular targeting. (nature.com)

Exercise like walking and biking lowers the levels of your body's stress hormones, such as adrenaline and cortisol, relieving tension. (ucla.edu)

The oral cavity is continually exposed to bacteria, their endotoxins and exototoxins, as well as physical stress. (bvsalud.org)

It is sometimes difficult to determine whether an animal is undergoing a normal process of adapting to a state of stress, for which intervention might not be indicated, or is in distress. (nationalacademies.org)
Magnesium and vitamin B6 contribute to the normal functioning of the nervous system. (activeshop.lv)
Vitamin B6 contributes to normal energy exchange, physical functions and normal functioning of the nervous system. (activeshop.lv)
Stress is a normal part of life. (nurx.com)

Recently, genome instability was a contributing factor to many age-related diseases. (researchsquare.com)

Will you be able to get rid of eating junk and other things that are not contributing to your physiological and mental health? (psychreg.org)

There are specialized treatments that can help reduce stress based on the current habits, lifestyle, and amount or presence of inducers of the person. (neo-bux.info)

The purposes of this book are to increase awareness of the sources and manifestations of stress and distress in laboratory animals and to increase ethical sensitivity in those who use and care for them. (nationalacademies.org)

The authors believe that in most experimental and husbandry situations laboratory animals need not experience substantial pain or stress and that prevention and alleviation of pain and stress in laboratory animals is an ethical imperative. (nationalacademies.org)

The optimization of industrial bioethanol production will depend on the rational design and manipulation of industrial strains to improve their robustness against the many stress factors affecting their performance during very high gravity (VHG) or lignocellulosic fermentations. (biomedcentral.com)
Psychosocial factors include the loss of a loved one, occupational stress, performance stress, ostracism and bullying, involuntary loneliness and lack of social support or a sense of meaning. (nordicclinic.se)

In order to confirm the diagnosis of exhaustion disorder physical and mental exhaustion must be present following a prolonged period of elevated stress. (wikipedia.org)
L-theanine helps establish balance in the neurotransmitter system, resulting in improvements in the mental/emotional and physical disturbances resulting from being overly stressed. (activeshop.lv)

The current experiment resulted from the interest of researchers at Johns Hopkins University concerning the differing effects that shear stress has on blood vessels and joints. (lifeextension.com)
Moreover, it can be a way to enable the service itself, as a result of the pharmacological effects of alcohol (soothing, exhilarating, stimulating, relaxing, sleep inducer, anesthetic and antiseptic) (5) . (bvsalud.org)

Regular exercise contributes to increased self-confidence. (ucla.edu)

Future research will aim at identifying specific inhibitors and/or inducers of UPR regulatory markers as well as expand the list of UPR-related animal models. (molvis.org)

Anatomy7

Organisms2

Diseases1

Chemicals and Drugs38

Phenomena and Processes19

Information Science2

Oxidative stress15

Potent2

Autophagy2

Immunity3

Abiotic2

Resistance5

Enzyme3

Metabolic4

Apoptosis1

Pathogenic1

Genes7

Endoplasmic reticulum1

Immune3

Mood3

Authors contributed equally1

Inflammatory1

Cells4

Metabolism2

Homeostasis1

Anxiety5

Exposure3

Processes2

Tissue1

Mediators1

Responses2

Common2

Survival1

Yeast1

Disorders2

Reactions1

Occurs2

Tolerance2

Taking care of1

Proteins1

Cortisol1

Bacteria1

Normal4

Diseases1

Things1

Presence1

Awareness1

Laboratory1

Factors2

Physical2

Effects2

Exercise1

Specific1