• Iohexol, sold under the trade name Omnipaque among others, is a contrast agent used for X-ray imaging. (wikipedia.org)
  • Omnipaque (Iohexol) injection. (wikipedia.org)
  • The company closed its Shanghai facility in March in response to a COVID-19 lockdown in the city, halting worldwide distributions of Omnipaque (iohexol) and Visipaque (iodixanol). (dotmed.com)
  • Plain CT-Scan and CT-scan Angiography (Omnipaque 240 mg /ml injectable Iohexol 750 mg/kg body weight with administration rate of 2 ml/s) were performed using (Siemens Somatom®) 2 detector scanner. (ivsajournals.com)
  • The DC Bead LUMI IFU recommends using contrast agents Omnipaque 350 (Iohexol 350) and Iomeron 400 (Iomeprol 400). (bostonscientific.com)
  • A recent study sought to establish the incidence of and risk factors for seizures after myelography with iohexol in dogs.1 In this retrospective case study, myelography was performed in 503 dogs by using iohexol (240 mg iodine/ml) injected into the cerebellomedullary cistern, lumbar cistern or both. (dvm360.com)
  • Contrast enhancement of ROI is affected by concentration of iodine contrast medium, volume and flow rate. (avmi.net)
  • Iohexol contains iodine and belongs to a class of drugs known as contrast media or dyes. (genev-als.in)
  • In April 2022, the COVID-19 pandemic caused a sudden and abrupt decrease in the production of iodine-based contrast media. (auntminnieeurope.com)
  • Among the alternative contrast agents they list are gadolinium for renal insufficiency, carbon dioxide for renal dysfunction, gastrografin for gastrointestinal access and catheter exchange, and cystografin for genitourinary access and procedures including nephrostomy and nephroureteral stent placement and exchanges. (dotmed.com)
  • 2,3] Nonetheless, since SCr is the only currently available measure of renal function, clinicians must employ the standard of an unexplained rise in SCr following contrast administration as evidence of CIN. (peterdsteinberg.com)
  • Other risk factors have been proposed including patient age, dose of contrast agent, poor cardiac function, multiple exposures to contrast agents over a brief duration, use of pharmacologic agents that tend to cause renal vasoconstriction, extracellular volume depletion, and certain diseases such as multiple myeloma. (peterdsteinberg.com)
  • Constataram-se aumentos significativos do índice de resistividade (IR) e da razão GGT:C urinária e evidências de aumento significativo do volume renal, 1,5 horas após a administração do contraste, somente no grupo que recebeu iohexol. (usp.br)
  • Um cão de 14 anos de idade, portador de insuficiência cardíaca e disfunção renal preexistente, desenvolveu a forma subclínica da NIC, reconhecida pela elevação de 0,5 mg/dL na creatinina sérica basal, 24 horas após a administração intravenosa do iohexol. (usp.br)
  • One week later, the left renal artery was clamped for 30 min to cause ischemia-reperfusion injury, and mice were injected with iohexol using a retro-orbital injection method. (asn-online.org)
  • Contrast-induced nephropathy (CIN), is an acute renal damage due to contrast agents. (preprints.org)
  • Use of less iodinated contrast is particularly crucial in patients with pre-existing renal dysfunction, as CM is concentrated in renal tubules, having a direct toxic effect, modulating tubular regulatory mechanisms, and producing renal vasoactive substances. (edu.au)
  • Risk of contrast induced nephropathy is considered low in human patients with no history or symptoms of renal disease. (edu.au)
  • Those concerns have largely focused on contrast-induced nephropathy (CIN), the commonest and most important complication of the use of iodinated radiocontrast material. (peterdsteinberg.com)
  • Contrast-induced nephropathy (CIN) is a type of acute nephropathy, secondary to intravascular administration of iodinated contrast media (ICM). (usp.br)
  • abstract: RATIONALE AND OBJECTIVES:Diabetic patients frequently suffer contrast media-induced nephropathy. (shengsci.com)
  • Contrast-induced nephropathy (CIN) is a major clinical problem associated with acute kidney injury during hospitalization, however therapeutic methods for CIN have made little progress. (asn-online.org)
  • In recent two years, as for the drug procurement in 22 cities in China , there were six major varieties of contrast media, namely, iohexol, iopromide, gadopentetate dimeglumine, iopamidol, ioversol and meglumine diatrizoate, of which the former three varieties were listed among the best-selling 200 drugs. (prnewswire.com)
  • According to the procurement of contrast media from sampled hospitals in 16 cities, iohexol and iopromide rank first and second respectively, accounting for 43% and 32% of market shares of CT contrast media respectively in domestic market. (prnewswire.com)
  • Also, with appropriate training, intravascular ultrasound can be used for vascular procedures without contrast media usage and decrease radiation exposure and operation times. (dotmed.com)
  • The relation between intravascular radiographic contrast media (RCM) and myointimal hyperplasia after percutaneous transluminal angioplasty is not known. (kent.ac.uk)
  • The CT contrast media shortage is a prime example of what happens when centralized purchasing decisions are disconnected from the day-to-day needs of healthcare professionals, he continued. (auntminnieeurope.com)
  • Dr. Linda Chu interviews Dr. Mahmud Mossa-Basha to discuss strategies in managing shortage of iohexol. (libsyn.com)
  • Studies in patients at very advanced stages of CKD in whom contrast is administered to assess vascular access pre-dialysis have shown that kidney function for these high-risk patients does not decline if less than 20 ml of contrast agents are infused with the venography. (peterdsteinberg.com)
  • This study aimed to assess the performance of our magnetic resonance thoracic ductography (MRTD) technique to visualize the thoracic duct and the surrounding 3D anatomical structures by combining MRTD and vascular contrast-enhanced thoracic computed tomography (CT) images in dogs. (openveterinaryjournal.com)
  • In addition, the images fused from MRTD and vascular contrast-enhanced CT image of the thorax could provide detailed anatomical annotations for preoperative planning. (openveterinaryjournal.com)
  • Concluiu-se que o IR foi capaz de monitorar a hemodinâmica intrarrenal e demonstrar, assim como a razão GGT:C urinária, maior potencial nefrotóxico do iohexol, quando comparado ao iodixanol. (usp.br)
  • It can be easily performed immediately after the initial nonenhanced CT with a single bolus of intravenous contrast medium and allows rapid diagnosis and treatment planning in the acute setting. (ajnr.org)
  • To determine the image quality and diagnostic performance of an optimized pulmonary computed tomography angiography (CTA) protocol in terms of radiation and contrast volume saving. (nih.gov)
  • A 43-year-old male patient on maintenance hemodialysis had an enhanced computed tomography scan examination with iohexol for the first time 10 min before regular hemodialysis therapy . (bvsalud.org)
  • The present study aimed to investigate the possibility of using dual-energy computed tomography (CT) before therapy to discriminate between normal breast tissue and tumor tissue in patients with breast cancer, without the need to use a contrast medium. (scirp.org)
  • Contrast-enhanced computed tomography (CT) is a common diagnostic modality to investigate abdominal pathology in dogs. (edu.au)
  • A radiographic contrast medium formerly used for oral cholecystography. (theodora.com)
  • Since their introduction in the 1950s, organic radiographic iodinated contrast media (ICM) have been among the most commonly prescribed drugs in the history of modern medicine. (medscape.com)
  • Right lateral fluoroscopic still image of a red-tailed hawk undergoing a gastrointestinal contrast study. (avma.org)
  • In tered diluted iohexol (10 mL in 1000 mL of water) as a contrast, brachytherapy using needle insertion improves gastrointestinal contrast medium before brachytherapy, target coverage [4], thereby enhancing local control and and patients also received an enema and underwent overall patient survival [5, 6]. (sagepub.com)
  • The nonionic monomers are the contrast agents of choice. (medscape.com)
  • Why does Australia have such an appetite for iohexol, which is one of the oldest (and arguably the cheapest) nonionic contrast agents? (auntminnieeurope.com)
  • In conclusion, ionic RCM have cytotoxic and cytostatic effects on VSMCs while nonionic media have no effects. (kent.ac.uk)
  • Iohexol is an iodinated non-ionic radiocontrast agent. (wikipedia.org)
  • Controversies continue over the diagnostic approach, prediction, and premedication in radiocontrast media (RCM) hypersensitivity. (aai.org.tr)
  • The following patient data were extracted by interview and from the hospital's radiology information system: height, weight, age, menstrual cycle, CT images of normal tissue and tumors with or without contrast medium, and the histopathological diagnosis of the aspiration biopsy. (scirp.org)
  • Iohexol improves the images obtained during a CT scan, so your doctor can more easily diagnose your condition. (genev-als.in)
  • Other investigators were using more innocuous contrast agents. (ajnr.org)
  • ACR's guidelines urge providers to prioritize contrast media use and rely on alternative agents. (dotmed.com)
  • In recent years, concerns about nephrotoxicity associated with high-osmolality contrast media (HOCM) have led to more widespread use of low- and iso-osmolality contrast agents in diagnostic imaging procedures. (peterdsteinberg.com)
  • Several experimental studies have demonstrated the medullary vasoconstriction that results from the administration of contrast agents. (peterdsteinberg.com)
  • While contrast agents may induce medullary ischemia in any subject, only certain individuals are at risk for CIN. (peterdsteinberg.com)
  • Classification of iodinated contrast agents by their molecular structures. (medscape.com)
  • Contrast agents are not a mere commodity that can be centrally purchased without a deep understanding of the physicochemical and clinical properties of these products, or the vulnerability of the supply chain," said Parizel. (auntminnieeurope.com)
  • May 13, 2021 With the increasing application of iodinated contrast agents, the adverse reactions and risks caused by iodinated contrast agents have attracted much attention. (beilupharma.com)
  • The exact protocol was done two times, immediately after complete injection of 3 ml/kg contrast medium via power injector (Sinopower-S Sino Medical-Device Technology Co., LTD) and 60 seconds later (delay phase) to allow the contrast medium to reach the suspected mass for CT-scan angiography achievement. (ivsajournals.com)
  • The osmolality of iohexol ranges from 322 mOsm/kg-approximately 1.1 times that of blood plasma-to 844 mOsm/kg, almost three times that of blood. (wikipedia.org)
  • High-osmolality contrast media consist of a tri-iodinated benzene ring with 2 organic side chains and a carboxyl group. (medscape.com)
  • The osmolality is related to some of the adverse events of these contrast media. (medscape.com)
  • 1] However, recent observations have called into question the specificity of the diagnosis, as up to 20% of patients who are hospitalized with cardiac disease and who never receive contrast media may also have a spontaneous rise in SCr equal to that seen in patients diagnosed with CIN. (peterdsteinberg.com)
  • In all conditions, regardless of contrast medium, the CT values of tumor tissues were higher than those of normal breast tissue, indicating the effectiveness of dual-energy CT (DE-CT) in the diagnosis of breast cancer. (scirp.org)
  • This thesis consists of two published articles (chapter 2 and 4), of which the final research aim was to determine if less iodinated contrast per kilogram TBW can be administered to overweight/obese dogs while maintaining adequate organ and vessel opacification to make a confident radiologic diagnosis. (edu.au)
  • This TAC was not suitable for homogeneous contrast enhancement because a precipitous change in the attenuation and the short contrast duration « 7 sec) of optimal attenuation, 200-300 HU. (avmi.net)
  • A "plateau type" showed the prolonged peak enhancement before decreasing the attenuation, and provided a longer contrast duration with homogeneous attenuation, considering that the 16 channel MOCT requires approximately 15 sec for cardiac scanning, especially using 800 mgl/kg 3D and 800 mgl/kg 40. (avmi.net)
  • Iohexol 350 mgI/ml at 700 mgI/kg TBW administration by a cephalic vein intravenous catheter, and a CT study performed with a fixed injection duration of 20 s, with the arterial and portal venous acquisition triggered 10 s and 35 s after aortic arrival respectively, was used for the subsequent part of the research project. (edu.au)
  • Acute thrombocytopenia is a rare complication induced by the contrast medium. (bvsalud.org)
  • Iohexol is featured with great security, high contrast ratio, lower osmotic pressure and small toxicity for human bodies etc. has become the best-selling contrast media in international market. (prnewswire.com)
  • The patient underwent fluoroscopy-guided spinal injection of 10 mL of iohexol 300 mgI/mL contrast medium from a single-dose vial prepared by a nurse in accordance with Centers for Disease Control and Prevention guidelines ( 10 ). (cdc.gov)
  • With providers still experiencing contrast media shortages from GE Healthcare's factory shutdown, a group of radiologists has published guidelines with alternative imaging methods and strategies for maintaining supplies. (dotmed.com)
  • A number of clinical practice guidelines are available regarding safe and effective practices for the use of iodinated contrast media. (medscape.com)
  • The patient is given various consistencies of food and liquid mixed with barium (or other contrast material), which allows the bolus to be visualized in real time on an X-ray during the swallow. (asha.org)
  • The presence of PE, image quality parameters [contrast attenuation, contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR)] and effective radiation dose (mSv) were assessed. (nih.gov)
  • The goal of this study is to determin the delay time for achieving adequate and consistent cardiovascular enhancement on the basis of the time attenuation curves (TAC) analysis according to various contrast media formulas. (avmi.net)
  • The diluted contrast solution with large volume provided the longer contrast plateau phase with homogeneous attenuation. (avmi.net)
  • The presence of a contrast agent such as iohexol in the subarachnoidal space may be associated with damage to the nervous tissue, and injection of contrast agent into the spinal cord may result in cardiorespiratory problems, seizures or death. (dvm360.com)
  • CT was performed after the intravenous injection of contrast medium. (openveterinaryjournal.com)
  • Myelography is an imaging examination that involves introducing a spinal needle into the cervical or lumbar spinal canal and injecting contrast material in the subarachnoid space (space around the spinal cord). (dvm360.com)
  • The skin tests were performed with the culprit agent if it was known, otherwise, with iohexol, one of the most commonly used RCM in Turkey. (aai.org.tr)
  • In dogs, iodinated contrast dose is commonly linearly increased based on total body weight (TBW). (edu.au)
  • One of the most important problems encountered in daily clinical practice is that patients do not recall which contrast agent has been used in previous exposures. (aai.org.tr)
  • From the clinical course , we diagnosed with contrast medium-induced thrombocytopenia . (bvsalud.org)
  • Chapter 2 is a retrospective study performed to determine the variability of major abdominal vessel and organ contrast enhancement and to establish any relationship with abdominal fat percentage in contrast enhanced CT studies, performed on 62 clinical patients at U-Vet Werribee Animal Hospital between February 2014 and February 2019. (edu.au)
  • May 29, 2023 -- A year on from the CT contrast media supply problems that caused severe disruption to medical imaging in many parts of the world, ESR Past President Prof. Paul Parizel, PhD, and his colleagues have presented the findings of their investigation into the crisis. (auntminnieeurope.com)
  • The Kidney Week 2023 mobile app features interactive maps, complete program, personalized scheduler, social media integration, and m. (asn-online.org)
  • Discussion/Conclusion: The dynamic CT scanning was performed to determine the optimal delay time and appropriate contrast media formulas in dogs. (avmi.net)
  • For the animal's safety, the minimum contrast media (CM) dose to achieve diagnostically appropriate contrast enhancement should be administered. (edu.au)
  • We should acknowledge that contrast media have potential to induce severe thrombocytopenia , even in patients on maintenance hemodialysis . (bvsalud.org)
  • Methods: This study was carried out using a cross-over design with four adult, beagles according to 12 different contrast formulas. (avmi.net)
  • Recent studies suggest that very large doses of contrast media may increase the risk of CIN, and that there is likely a low dose that does not convey such a risk. (peterdsteinberg.com)
  • Intravenous Iohexol (240 or 350 mgI/ml) with a dose range of 660-880 mgI/kg TBW administered by a power injector (1.8 - 3.0 ml/s) and saline chaser was the standard injection protocol used at this institution. (edu.au)
  • Additionally, 4 concentrations of positive contrast were evaluated using different dilution factors with 0.9% saline: undiluted (UO), 1:1 (20), 1:2 (3D), and 1:3 (40). (avmi.net)
  • Three different dosages of positive contrast medium (iohexol [300 mgl/ml]), were evaluated: 300 mgl/kg, 400 mgl/kg, and 800 mgl/kg. (avmi.net)
  • Results: According to positive contrast formulas, two types of TAC including "peak arc type" or "plateau type" were obtained. (avmi.net)
  • Moreover, MRI does not require contrast media, and it enables visualization of morphological details of the thoracic structures. (openveterinaryjournal.com)
  • DC Bead LUMI must be suspended in soluble iodinated contrast (a minimum of 20ml per vial) to achieve effective delivery through microcatheters and to aid visualization during administration. (bostonscientific.com)
  • She also says, "they may serve patients in the long term by minimizing both contrast media load and radiation exposure. (dotmed.com)
  • A recent study sought to establish the incidence of and risk factors for seizures after myelography with iohexol in dogs. (dvm360.com)
  • Twelve of the dogs that experienced postmyelographic seizures had been injected with more than 8 ml of iohexol. (dvm360.com)
  • Higher prevalence of seizures in large dogs, compared with smaller dogs, may be caused by administration of larger total volumes of contrast agent per volume of cerebrospinal fluid. (dvm360.com)
  • The thoracic ducts were identified in MRTD images of all dogs, and the surrounding anatomical structures were located with the aid of contrast-enhanced thoracic CT. (openveterinaryjournal.com)
  • Contrast medium-induced severe thrombocytopenia in patient on maintenance hemodialysis: a case report and literature review. (bvsalud.org)
  • There was no patient with contraindication to intravenously administered iodinated contrast material in this series. (ajnr.org)
  • Stephany Mazur, MD discusses a new article in AJR that focuses on factors predicting background parenchymal enhancement in contrast-enhanced mammography (CEM). (arrs.org)
  • A "peak arc type" showed progressively increase of contrast enhancement and reached the peak quickly and then declined rapidly. (avmi.net)
  • Following this retrospective study, variability of abdominal organ/vessel contrast enhancement contributed by CM injection method was evaluated and outlined in chapter 3. (edu.au)
  • This was done in attempt to minimise contribution of varied CM injection techniques on organ/vessel contrast enhancement variances prior to the second part of the research project. (edu.au)
  • Chapter 4 was a prospective study where we hypothesised that LBW adjusted dosing would not affect the diagnostic quality of the abdominal CT study, will minimise negative physiological effects, and reduce variability of contrast enhancement in major abdominal organs and vessels as compared to dosing according to TBW. (edu.au)
  • Research and Markets ( http://www.researchandmarkets.com/research/9g868h/research_and ) has announced the addition of the "Research and Development Forecast of China Contrast Media (Contrast Agent) Market, 2014" report to their offering. (prnewswire.com)
  • By contrast, DE-CT showed limited potential for distinguishing ductal carcinoma in situ from invasive ductal carcinoma. (scirp.org)
  • With the mushroom growth of world diagnostic imaging equipments and apparatuses, as for X-CT contrast media, iodinated contrast media serving as the main one is witnessing unprecedented development. (prnewswire.com)
  • They also recommend department heads from both diagnostic and interventional teams, including non-radiological divisions, work together to manage contrast media usage. (dotmed.com)
  • The control group was treated with only 15% fetal calf serum (FCS) containing medium. (kent.ac.uk)
  • MSCs cultured in Dulbecco's Modified Eagle Medium containing 10% fetal bovine serum (S-MSCs) or SF-MSCs were then injected through the tail vein. (asn-online.org)
  • In recent two years, domestic hospitals with certain strength put their attention on testing and examining, so they increased investment in imaging equipments, resulting in bringing momentum for the growth of contrast media market. (prnewswire.com)
  • They first advise creating a priority matrix for procedures that require iodinated contrast media and ones that can be deferred, as well as one for when alternative imaging modalities can be used, and another for when alternative contrast media can be applied. (dotmed.com)
  • It works by adding contrast to body parts and fluids in these imaging tests. (genev-als.in)