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  • yeast
  • To this end, more recently it was shown that it is feasible to apply this method to large eukaryotic genomes with the mapping attempt on yeast Another recent application of denaturation of mapping is haplotype-phasing. (wikipedia.org)
  • locus
  • Fine-mapping and construction of a bovine contig spanning the ovine callipyge locus. (ac.be)
  • Analysis of more than 500 backcross and intercross progeny maps the hyh locus to proximal Chr 7, approximately 13 cM centromeric to its originally reported map position. (deepdyve.com)
  • loci
  • Using Type I loci mapping to the IDVGA30-OY3 interval as anchor points, we have constructed a 1.4-Mb bovine BAC contig containing the IDVGA30-OY3 interval. (ac.be)
  • By taking advantage of allelic variation revealed by heterologous probes, the positions of corresponding loci on the wheat ( Triticum aestivum ), rice, maize, sugarcane, and Arabidopsis genomes are being interpolated on the sorghum physical map. (plantphysiol.org)
  • produces
  • Assembling the reads from such a pair (including, of course, only one copy of the identical sequence) produces a longer contiguous read (contig) of sequenced DNA. (wikipedia.org)
  • First round of de novo assembly produces hundreds to thousands of contigs, which can be computationally profiled in terms of their melting temperature. (wikipedia.org)
  • sequences
  • Goals include automating methods and optimizing techniques to extract the maximum useful information from maps and sequences. (lsu.edu)
  • A contig is a set of gel readings that are related to one another by overlap of their sequences. (wikipedia.org)
  • The new constraints placed on the orientation of the contigs allows for the placement of highly repeated sequences in the genome. (wikipedia.org)
  • This allows unique fingerprints or 'barcodes' to be generated for molecules with different sequences not unlike restriction mapping. (wikipedia.org)
  • CHROMOSOMES
  • Although originating and centered in the U.S., laboratories across the globe contributed to the mapping and sequencing of the haploid human genome's 22 autosomes and 2 sex chromosomes. (stanford.edu)
  • region
  • A contig (from contiguous) is a set of overlapping DNA segments that together represent a consensus region of DNA. (wikipedia.org)
  • distances
  • Since actual base-pair distances are generally hard or impossible to directly measure, physical maps are actually constructed by first shattering the genome into hierarchically smaller pieces. (wikipedia.org)
  • molecule
  • Physical maps describe the chemical characteristics of the DNA molecule itself. (lsu.edu)
  • methods
  • BAC contigs are constructed by aligning BAC regions of known overlap via a variety of methods. (wikipedia.org)
  • Even though modern sequencing methods reduced the need for denaturation mapping, it is still being used for specific purposes, such as detection of large scale structural variants. (wikipedia.org)
  • candidate
  • Because of the predictable nature of a denaturation map, given a sequence it is possible to computationally generate a candidate map with relatively high confidence based on the Poland-Sherga model. (wikipedia.org)
  • provide
  • Both physical maps and diversity maps suggest interesting features that may be integrally related to the chromosomal context of DNA-progress in cytology promises to provide a means to elucidate such relationships. (plantphysiol.org)
  • often
  • It was not uncommon to ribosomal DNA and compare the resulting maps of related organisms not unlike 16s rRNA identification method that is often used today. (wikipedia.org)