AtropineAtropaHyoscineTropane alkaloidHyoscyamusContain tropane alkaloidsSULFATEScopolamine and hyoscyamineNightshadeAssociated with tropane alkaloidsAnticholinergicSolanaceaeDaturaCompoundsAminesMuscarinic receptorsToxicityPhenobarbitalMethenamineTabletSymptomsGenusAnticholinergicsIsoquinolineBerriesTinctureRacemateRootsBiosynthesisMedicationTropic acidGastrointestinalDrugsToxicScopoliaAllergicPlantsPrecautionsDosesDuboisiaDerivativesPlantDrowsiness
Atropine15
- This product contains several medications: belladonna alkaloids (made up of the drugs hyoscyamine, atropine, and scopolamine) and phenobarbital. (imedix.com)
- Hyoscyamine Sulfate is the sulfate salt of a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits anticholinergic activity. (lktlabs.com)
- in the factory isolation of the alkaloid from plants, it is traditionally obtained its inactive racemate - atropine in the form of a salt - Atropini sulfas. (medprep.info)
- Hyoscyamine is the 3(S)-endo isomer of atropine. (lookformedical.com)
- nervous system affected by the alkaloids jasciamine, atropine, and belladonnin. (poultryhelp.com)
- The tropane alkaloids atropine, scopolamine, and hyoscyamine are highly anticholinergic compounds found in a number of plants. (medscape.com)
- Only the 1: 1 mixture of ( R ) - and ( S ) -hyoscyamine is called atropine (see Cahn-Ingold-Prelog convention for naming). (zxc.wiki)
- The sulphate of this alkaloid is sometimes used as a substitute for atropine as a mydriatic. (henriettes-herb.com)
- Atropine, a naturally occurring belladonna alkaloid, is a racemic mixture of equal parts of d- and l-hyoscyamine, whose activity is due almost entirely to the levo isomer of the drug. (pharmacycode.com)
- Atropa belladonna is a highly poisonous plant which contains variety of active alkaloids such as atropine, scopolamine and many others. (ijpsonline.com)
- Tropane alkaloids include three important ones from our perspective - atropine, scopolamine , and hyoscyamine . (allaboutheaven.org)
- Atropine, scopolamine , and hyoscyamine are the most powerful known anticholinergics in existence. (allaboutheaven.org)
- Of toxicological importance are the tropane alkaloids (S)-hyoscyamine, atropine, which is formed as a racemate of (S)- and (R)-hyoscyamine during drying or as a result of extraction, and scopolamine. (org.rs)
- It is the levorotary isomer of atropine (third of the three major nightshade alkaloids) and thus sometimes known as levo-atropine. (curecrowd.com)
- ATROPINE - poisonous, crystalline substance belonging to a class of compounds known as alkaloids and used in medicine. (slovar-vocab.com)
Atropa6
- Belladonna, Belladonna - species of Atropa L. (medprep.info)
- Atropa belladonna is a medicinal plant and main commercial source of tropane alkaloids (TAs) including scopolamine and hyoscyamine, which are anticholine drugs widely used clinically. (bvsalud.org)
- It is prepared from plant Atropa belladonna, commonly known as 'deadly nightshade' known to be most poisonous plant in world[ 3 ]. (ijpsonline.com)
- The term "tropane" is derived from just one genus in the family Solanaceae - Atropa (the belladonna genus), named after the Greek Fate, Atropos, who cut the thread of life. (allaboutheaven.org)
- It is a secondary metabolite found in certain plants of the Solanaceae family, including henbane ( Hyoscyamus niger ), mandrake ( Mandragora officinarum ), jimsonweed ( Datura stramonium ), tomato ( Solanum lycopersicum ) and deadly nightshade ( Atropa belladonna ). (curecrowd.com)
- NL Atropa, genus name of belladonna, fr. (slovar-vocab.com)
Hyoscine2
- This alkaloid is called scopolamine or hyoscine. (medprep.info)
- Hyoscyamine should not be confused with hyoscine, an older alternate name for the related nightshade-derived anticholinergic scopolamine . (curecrowd.com)
Tropane alkaloid2
- Although most tropane alkaloids cause an anticholinergic syndrome, a case report indicates that the tropane alkaloid-containing medicinal herb Erycibe henri Prain ("Ting Kung Teng") contains a tropane alkaloid that may cause a cholinergic syndrome, as well as kidney, liver, and erythrocyte toxicity. (medscape.com)
- Hyoscyamine is a tropane alkaloid . (curecrowd.com)
Hyoscyamus1
- Duboisine is very similar to, if not identical with, hyoscyamine, and the physiological effects of it are practically the same as those of the alkaloids of belladonna, hyoscyamus and stramonium. (henriettes-herb.com)
Contain tropane alkaloids1
- Also known as 'devil's berries' or 'death cherries', the deadly nightshade plant and its berries are very poisonous and contain tropane alkaloids that cause hysteria, hallucinations, erratic behaviour and delirium. (australiangeographic.com.au)
SULFATE6
- HYOSCYAMINE SULFATE is an alkaloid of belladonna. (drugs.com)
- C 34 H 48 N 2 O 10 S. Hyoscyamine Sulfate is an alkaloid of belladonna. (nih.gov)
- HYOSCYAMINE SULFATE is a parasympatholytic which relaxes smooth muscles and thus produces an antispasmodic effect. (nih.gov)
- Psychosis has been reported in sensitive individuals given hyoscyamine sulfate. (rxwiki.com)
- Myers J, Moro-Sutherland D, Shook J. Anticholinergic poisoning in colicky infants treated with hyoscyamine sulfate. (lktlabs.com)
- What Form(s) Does Hyoscyamine Sulfate Come In? (optionrx.com)
Scopolamine and hyoscyamine1
- Rich in alkaloids such as scopolamine and hyoscyamine, if ingested by humans, the trumpets can cause diarrhoea, confusion, migraines, paralysis and even death. (australiangeographic.com.au)
Nightshade1
- Deadly Nightshade, also known as belladonna, is an extremely poisonous plant native to Europe and parts of Asia. (homesteadbackyard.com)
Associated with tropane alkaloids1
- Other tropane derivatives, found in the same plants in small quantities, as well as liquid and volatile pyridine derivatives, often associated with tropane alkaloids, are of no practical importance. (medprep.info)
Anticholinergic3
- [ 14 ] This is considered atypical for the tropane alkaloids, which are predominantly strongly anticholinergic. (medscape.com)
- Toxicity from plants containing tropane alkaloids manifests as classic anticholinergic poisoning. (medscape.com)
- Tropane alkaloids (TA) including anisodamine, anisodine, hyoscyamine and scopolamine are a group of important anticholinergic drugs with rapidly increasing market demand, so it is significant to improve TA production by biotechnological approaches. (biomedcentral.com)
Solanaceae2
- Usually, the sum of alkaloids in all Solanaceae species includes both main alkaloids, but in all possible proportions, one of them prevails. (medprep.info)
- Some medicinal plants of Solanaceae are rich in tropane alkaloids(TAs), which have significant pharmacological activities. (bvsalud.org)
Datura2
- Many cultures worldwide add plants with tropane alkaloids (particularly Datura species) to alcoholic beverages to increase intoxication. (medscape.com)
- The cereal was found to have been contaminated with tropane alkaloids from seeds of Datura stramonium that had invaded grain fields. (medscape.com)
Compounds6
- The compounds found in plants are diverse, with most in four biochemical classes: alkaloids, glycosides, polyphenols, and terpenes. (wikipedia.org)
- Alkaloids are called natural nitrogen-containing compounds of the main character, formed in plants. (medprep.info)
- Groups of proteinogenic amines (for example, tyramine) and betaines (stakhidrin, trigonelline, etc.) adjoin the alkaloids, which are considered as transitional compounds from the simplest nitrogen-containing compounds (methylamine, trimethylamines, etc.) to the alkaloids proper. (medprep.info)
- [ 1 ] The alkaloids represent a very diverse group of medically significant compounds that include well-known drugs such as the opiates. (medscape.com)
- Antidiarrheal agents include several drug classes, including opioid Opioid Compounds with activity like opiate alkaloids, acting at opioid receptors. (lecturio.com)
- Background: Since alkaloids are nitrogenous compounds, the availability of nitrogen [N] is expected to play an important role in the biosynthesis and accumulation of alkaloids in plants. (bvsalud.org)
Amines1
- A subgroup of the alkaloids is the alkaloid amines, which include three major pharmacologic groups: the hallucinogenic alkaloid amines, the stimulant alkaloid amines, and the tropane alkaloids (also called the belladonna alkaloids or bicyclic alkaloids). (medscape.com)
Muscarinic receptors1
- Hyoscyamine functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as well as the eye, heart, bladder, and gastrointestinal tract. (lktlabs.com)
Toxicity3
- However, due to its toxic nature and adverse teratogenic effect, it is important to investigate the possible toxicity and safety level of belladonna mother tincture. (ijpsonline.com)
- In this study, zebrafish embryos were used to evaluate fetal embryo toxicity of the belladonna mother tincture. (ijpsonline.com)
- Further developmental toxicity studies on animals need to be carried out to validate use of belladonna mother tincture clinically in low concentration or high dilution.s. (ijpsonline.com)
Phenobarbital7
- Belladonna alkaloid combinations and phenobarbital are used to relieve cramping pains in conditions such as irritable bowel syndrome and spastic colon. (medlineplus.gov)
- Belladonna alkaloid combinations and phenobarbital come as a regular tablet, a slow-acting tablet, capsule, and liquid to take by mouth. (medlineplus.gov)
- Take belladonna alkaloid combinations and phenobarbital exactly as directed. (medlineplus.gov)
- If you have any of these symptoms, stop taking belladonna alkaloids and phenobarbital and call your doctor immediately. (medlineplus.gov)
- Tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take while taking belladonna alkaloid combinations and phenobarbital. (medlineplus.gov)
- If you become pregnant while taking belladonna alkaloids and phenobarbital, call your doctor. (medlineplus.gov)
- Older adults should receive low doses of belladonna and phenobarbital because higher doses do not function better and can cause serious side effects. (medlineplus.gov)
Methenamine2
- hyoscyamine and methenamine cross the placenta. (drugs.com)
- however, methenamine and traces of hyoscyamine are excreted in breast milk. (drugs.com)
Tablet1
- Hyoscyamine comes as a tablet, an orally disintegrating tablet, an extended-release (long-acting) capsule, an elixir, and a solution to take by mouth. (rxwiki.com)
Symptoms6
- Belladonna alkaloids help to reduce the symptoms of stomach and intestinal cramping. (imedix.com)
- Hyoscyamine is a prescription medication used to used to control symptoms associated with disorders of the gastrointestinal (GI) tract. (rxwiki.com)
- Chinese herbal medicines containing tropane alkaloids have been used to treat asthma, chronic bronchitis, pain, and flu symptoms. (medscape.com)
- Symptoms usually occur 30-60 minutes after ingestion and may continue for 24-48 hours because tropane alkaloids delay gastric emptying and absorption. (medscape.com)
- Specifically, Belladonna is indicated in case of symptoms due to inflammation , which manifests itself with sudden redness, heat and / or burning, or swelling. (treasurenatural.com)
- Hyoscyamine may also be used to treat certain heart conditions, to control the symptoms of Parkinson's disease and rhinitis (runny nose), and to reduce excess saliva production. (optionrx.com)
Genus2
- Liliales) is a genus of perennial herbs known for the production of unique bioactive steroidal alkaloids. (bvsalud.org)
- Our data represent the first cross-species analysis of steroidal alkaloid biosynthesis in the genus Veratrum and indicate that the metabolic properties of V. maackii and V. nigrum are broadly conserved despite their distinct alkaloid profiles. (bvsalud.org)
Anticholinergics1
- Belladonna alkaloids belong to a class of drugs known as anticholinergics/antispasmodics. (imedix.com)
Isoquinoline2
- isoquinoline alkaloid causes "epidemic dropsy" in humans. (poultryhelp.com)
- Isoquinoline alkaloids - Isoquinoline alkaloids 1-Benzyl isoquinoline type: Papaverine: An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. (powershow.com)
Berries1
- Poisonings with the berries of belladonna take a leading position in the statistics of poison control centers in the context of plant poisonings. (org.rs)
Tincture5
- From the leaves and herbs of belladonna (Folium et Herba Belladonnae), prepare tincture, thick and dry extracts, which are part of numerous medicines. (medprep.info)
- Do not worry, the homeopathic remedy is obtained by diluting and dynamizing the tincture of Belladonna and when it is taken to our body only the message of rebalancing of the decompensation arrives. (treasurenatural.com)
- Briefly, eggs were exposed to different concentration (1, 5 and 10 %) of belladonna mother tincture and ethyl alcohol for 1 h. (ijpsonline.com)
- Results showed that exposure to belladonna mother tincture at higher concentration (5, 10 %) cause embryonic malformation including pericardial edema, increase in body length, eye width and heart rate, while decrease hatching rate with no effect on mortality. (ijpsonline.com)
- The behavioural parameters revealed that belladonna mother tincture increases the locomotor activity of larvae at its 1 % concentration rather than 5 and 10 % in comparison to control. (ijpsonline.com)
Racemate1
- it is a racemate (1: 1 mixture) of the isomers ( R ) - and ( S ) - hyoscyamine , which is formed during isolation by racemization from the natural product ( S ) -hyoscyamine. (zxc.wiki)
Roots2
- The leaves of belladonna contain 0.3-0.75% of the amount of alkaloids (mainly hyoscyamine), in the roots - a little more. (medprep.info)
- We propose that ERF1A, CYP90G1-1 and CYP76AH1 are specifically involved in the key steps of steroidal alkaloid biosynthesis in V. maackii roots. (bvsalud.org)
Biosynthesis1
- The diversity of these alkaloids depends on which amino alcohol was formed in the process of biosynthesis from tropane (tropine, scopine or ecgonine) and with what organic acids these amino alcohols subsequently formed esters. (medprep.info)
Medication2
- patients intolerant of belladonna alkaloids may be intolerant of this medication also. (drugs.com)
- Although the remedial properties of scopolia have a close resemblance to the characteristics of belladonna, this rudimentary medication has hardly been utilized as an internal medicine. (herbs2000.com)
Tropic acid1
- Tropine in nightshades is esterified with tropic acid to form the alkaloid hyoscyamine. (medprep.info)
Gastrointestinal2
- gastrointestinal tract affected by alkaloid toxins. (poultryhelp.com)
- Hyoscyamine is used to provide symptomatic relief to various gastrointestinal disorders including spasms, peptic ulcers , irritable bowel syndrome , diverticulitis , pancreatitis , colic and cystitis . (curecrowd.com)
Drugs4
- tell your doctor and pharmacist if you are allergic to belladonna, any barbiturate medicine, tartrazine (a yellow dye in some processed foods and drugs), or any drug. (medlineplus.gov)
- Hyoscyamine belongs to a group of drugs called Belladonna alkaloids. (rxwiki.com)
- Of natural pharmacologically active substances, alkaloids are the main group from which modern medicine draws the largest number of highly effective drugs. (medprep.info)
- Belladonna is one of the most popular homoeopathic drugs used in baby teething, sudden severe pain and pain with inflammation or infection[ 2 ]. (ijpsonline.com)
Toxic1
- infants and young children are especially susceptible to the toxic effect of the belladonna alkaloids. (drugs.com)
Scopolia3
- Scopolia normally thrives well in humid, rock-strewn places in mountainous regions and has a close resemblance to belladonna - in appearance as well as in its features. (herbs2000.com)
- Compared to belladonna, the barks of Scopolia Carniolica are less chunky and even the enclosed starch granules are lesser in size. (herbs2000.com)
- In America, scopolia has been used for several years in manufacturing belladonna plasters. (herbs2000.com)
Allergic1
- Do not use it if you had an allergic reaction to hyoscyamine. (optionrx.com)
Plants2
- According to world literature, by the end of the past decade, the number of alkaloids isolated from the higher plants of the Earth's flora exceeded 5000. (medprep.info)
- According to modern concepts, alkaloid-bearing plants make up 10% of the entire world flora. (medprep.info)
Precautions1
- See the "Hyoscyamine Precautions" section. (rxwiki.com)
Doses1
- use with caution in elderly patients as they may respond to usual doses of hyoscyamine with excitement, agitation, drowsiness, or confusion. (drugs.com)
Duboisia1
- The alkaloid obtained from the leaves of Duboisia myoporoides , Robert Brown (Nat. (henriettes-herb.com)
Derivatives1
- The plant contains alkaloids with fused pyrrolidine and piperidine rings (derivatives of tropine, scopine and ecgonine). (medprep.info)
Plant2
- In the same species, the amount of alkaloids is different in different organs of the plant and, moreover, varies depending on the phase of vegetation and environmental conditions. (medprep.info)
- Alkaloids are plant metabolites that have a nitrogen-containing chemical ring structure, alkali-like chemical reactivity, and pharmacologic activity. (medscape.com)
Drowsiness1
- Hyoscyamine can also cause blurred vision, drowsiness, and dizziness. (rxwiki.com)