• When kidneys experience a drop in blood perfusion, they release renin, which converts angiotensinogen into angiotensin I. Then angiotensin converting enzyme (ACE) converts angiotensin I into angiotensin II, a potent vasoconstrictor. (truman.edu)
  • Angiotensin II is a very strong vasoconstrictor of the arterioles and to a lesser extent the veins. (ceufast.com)
  • Thus it is known as a laxative, diuretic, and a phlebotherapeutic ( beneficial to veins ) agent bilingual. (la-maf.com)
  • The allergen or non-allergen factors stimulates the vagus nerve to release acetylcholine which produces constriction of the airways and increased glandular secretions which plug the small airways in the lungs leading to bronchial edema and airway obstruction. (dentalcare.com)
  • Known hypersensitivity to bupivacaine or to any local anesthetic agent of the amide-type or to other components of Bupivacaine Hydrochloride Injection/Bupivacaine Hydrochloride and Epinephrine Injection. (pfizermedicalinformation.com)
  • PROPOFOL (2,6-diisopropylphenol) is a chemically distinct intravenous anesthetic agent. (silverchair.com)
  • Preferential antagonism of α 1 -adrenoceptors with prazosin (1 mg/kg iv) abolished the vasoconstrictor response to PE but had a lesser effect on the response to B-HT 920. (researchwithrutgers.com)
  • Drug used to cause constriction of the blood vessels. (ebi.ac.uk)
  • Blue arrows indicate the constriction of pulmonary arteries, black arrows the direction of blood flow. (ersjournals.com)
  • Agrimony is also considered a very useful agent in skin eruptions and diseases of the blood, pimples, blotches, etc. (zhealthinfo.com)
  • Constriction of the arterioles increases the peripheral resistance and thereby raises the arterial pressure back towards normal which elevates the arterial blood pressure. (ceufast.com)
  • There is an overwhelming mass of evidence demonstrating the development of endothelial dysfunction in animal models of diabetes and in human blood vessels from diabetic patients, as evidenced by increased release of reactive oxygen species, decreased nitric oxide (NO) bioactivity, decreased release of prostacyclin (PGI 2 ), and enhanced endothelial production of vasoconstrictor thromboxane (Tx)A 2 /prostaglandin (PG)H 2 in early stages of diabetes ( 1 - 3 ). (diabetesjournals.org)
  • Patients should be instructed to promptly report the occurrence of headache or other unusual symptoms, e.g., palpitation and/or tachycardia, a sense of constriction in the throat or chest, sweating, dizziness, neck stiffness, nausea, or vomiting. (marplan.com)
  • Treatment is with statins, anti-hypertensive and antiplatelet agents, and, in some cases (depending on the degree of stenosis and associated symptoms) , surgical revascularization. (lecturio.com)
  • An agent that selectively binds to and activates alpha -adrenergic receptors. (ebi.ac.uk)
  • Although all patients are at risk for methemoglobinemia, patients with glucose-6-phosphate dehydrogenase deficiency, congenital or idiopathic methemoglobinemia, cardiac or pulmonary compromise, infants under 6 months of age, and concurrent exposure to oxidizing agents or their metabolites are more susceptible to developing clinical manifestations of the condition. (themeditary.com)
  • With reference to local anesthetics and vasoconstrictors used in dentistry, the physicians still have some doubts about their use, even with the literature supporting their safety in this period. (bvsalud.org)
  • Adrenalin 1:1000 Infectopharm is recommended as the initial and primary therapeutic agent in the treatment of anaphylaxis by every recognised authority in allergy, and its appropriate use in these circumstances is widely documented in medical literature. (pillintrip.com)
  • Some of these agents are currently under evaluation in clinical trials for treatment of hypertension and diabetes. (frontiersin.org)
  • Because of the documented vasoconstrictor influence of marijuana, the researchers hypothesized that daily intake of the subjects played a crucial position in their treatment. (mjseedscanada.ca)
  • It would not have any coagulation agents, and it is never a supplement for conventional hemophilia care and does serve to minimize side effects. (mjseedscanada.ca)
  • Steroids and immunosuppressive agents are reserved for patients with severe disease. (basicmedicalkey.com)
  • 21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. (lookformedical.com)
  • Indeed, it was shown that vasopressin is a more potent vasoconstrictor than angiotensin II or norepinephrine and is capable of increasing systemic vascular resistance in doses less than those required to produce maximum urine concentration. (onteenstoday.com)
  • Angiotensin II is a potent vasoconstrictor that plays an immediate role in the regulation of blood pressure. (onteenstoday.com)
  • Angiotensin I is then converted by angiotensin converting enzyme (ACE) to angiotensin II, a potent endogenous vasoconstrictor substance. (theodora.com)
  • 19 published his findings on cortisone causing dramatic improvements in patients with rheumatoid arthritis, corticosteroids have become established as the most potent anti-inflammatory agents in the pharmacotherapy of various chronic inflammatory diseases, including asthma 20 . (ersjournals.com)
  • Alternative vasopressor for patients with septic shock who: (1) develop tachyarrhythmias on norepinephrine, epinephrine, or dopamine, (2) have persistent shock despite use of two or more vasopressor/inotropic agents including vasopressin (salvage therapy), or (3) high cardiac output with persistent hypotension. (onteenstoday.com)
  • Drugs used to cause constriction of the blood vessels. (lookformedical.com)
  • Ophthalmic anti-allergic treatment includes topical mast cell stabilizers, oral and topical antihistamines, antihistamine-vasoconstrictor combinations, dual action agents with mast cell-stabilizing, and antihistaminic properties, and anti-inflammatory agents including steroids and non-steroidal drugs. (frontiersin.org)
  • This usually occurs overnight and is mainly triggered by emotional stress, vasoconstrictor drugs, or smoking . (nursestudy.net)
  • It can prevent or eliminate spasm of vessels caused by various vasoconstrictor drugs. (happyfamilystoreonline.com)
  • Vasopressor agents are also commonly used to treat hypoperfusion by inducing constriction of arterioles and venules and increasing cardiac contractility. (nih.gov)
  • Known hypersensitivity to bupivacaine or to any local anesthetic agent of the amide-type or to other components of MARCAINE / MARCAINE WITH EPINEPHRINE. (nih.gov)
  • Analgesic agent such as lidocaine, and a vasoconstrictor such as epinephrine. (homeopathy360.com)
  • Likewise, solutions of CARBOCAINE containing a vasoconstrictor, such as epinephrine, should be used with extreme caution in patients receiving monoamine oxidase inhibitors (MAOI) or antidepressants of the triptyline or imipramine types, because severe prolonged hypertension may result. (pfizermedicalinformation.com)
  • The three peptides produce vasoconstrictor and pressor responses in various parts of the body. (lookformedical.com)
  • Sectioning the cardiac sympathetic nerves or administering ganglion blocking agents dimin- ishes these responses. (nih.gov)
  • Sympathomimetic agents are a group of chemical compounds that are able to activate the sympathetic nervous system either directly via adrenergic receptors or indirectly by increasing endogenous catecholamine levels or mimicking their intracellular signaling pathways. (bvsalud.org)
  • Methyldopa probably also acts as an α2-receptor agonist to attenuate output of vasoconstrictor adrenergic signals to the peripheral sympathetic nervous system. (trc-p.nl)
  • Ergotamine is an alpha-adrenergic antagonist and serotonin antagonist that causes constriction of the peripheral and cranial blood vessels. (medscape.com)
  • Dihydroergotamine is an alpha-adrenergic blocking agent that has a direct stimulating effect on the smooth muscle of peripheral and cranial blood vessels and depresses central vasomotor centers. (medscape.com)
  • DE exposure did not affect KCl and U-46619 constrictor responses, while NOS inhibition augmented KCl constriction equally in both groups. (nih.gov)
  • The endothelin type B (ET(B)) receptor antagonist BQ-788 (10 microM) inhibited ET-1 constriction in DE but not Air arteries, and constriction in the presence of the antagonist was not different between groups. (nih.gov)
  • This inflammatory response is also seen in the rodent chronic nerve constriction injury model that is produced by loose ligation of the sciatic nerve. (nih.gov)
  • Although synthetic sympathomimetic agents are mostly seen as toxic, natural sympathomimetic agents are considered more complacently in the terms of safety in the vision of the lay public. (bvsalud.org)
  • Here, we aim to discuss the pharmacological and mainly toxicological aspects related to sympathomimetic natural agents, in particular of trace amines, compounds derived from plants like ephedra and khat, and finally cocaine. (bvsalud.org)
  • The main purpose of this review is to give a scientific and updated view of those agents and serve as a reminder on the safety issues of natural sympathomimetic agents most used in the community. (bvsalud.org)
  • These results suggested that FGF21 might influence sleep/wake regulation by inducing production of an anti-stress agent and/or ketone bodies, which may result in resilience to social stress. (tokushima-u.ac.jp)
  • 2004). Neonates born to mothers chronically abusing illicit opioids or provided with maternal medication-assisted treatment, such as methadone or buprenorphine, are frequently born with a passive dependency to those specific agents. (drugpolicyfacts.org)
  • Single-dose solutions contain no added bacteriostat or anti-microbial agent and unused portions should be discarded after use. (nih.gov)
  • Sumatriptan is the first of the antimigraine agents that directly affect 5-HT1 receptors. (medscape.com)