VascularArterialBiomechanicsBoundary conditionsSimulationFluidContractionPulsatile2016FinitePulmonaryMathematicalMyocardial infarctionComputational modelsEstimationDiseasesSimulationsPhysiologicalSystemPumpExperimentsElasticPredictMethodsAnalysisDesignClinicalAreasResultsSetsBodyNormalInputMethodSearchUniversity
Vascular8
- The Vascular Model Repository , a sister project of SimVascular, is a library of computational models of normal and diseased human cardiovascular and pulmonary anatomy and input and output boundary conditions for various physiologic states. (github.io)
- Mascheroni, P., Penta, R., Merodio, J. (2023) The impact of vascular volume fraction and compressibility of the interstitial matrix on vascularised poroelastic tissues Biomechanics and Modeling in Mechanobiology, 22, pp. 1901-1917. (gla.ac.uk)
- 2) The role of pulsatile arterial load (vascular stiffness in particular) in cardiovascular function. (pitt.edu)
- One of the hypotheses being investigated is that aberrant vascular stiffness changes are involved in the genesis of certain cardiovascular pathologies (e.g., preeclampsia, isolated systolic hypertension in elderly). (pitt.edu)
- 3) Cardiovascular actions of relaxin and its therapeutic potential in the context of three pathologies: (i) relaxin-induced maternal vascular remodeling and associated functional benefits in preeclampsia, (ii) relaxin-induced left atrial remodeling and suppression of atrial fibrillation, and (iii) relaxin-induced left ventricular remodeling and associated functional benefits in the setting of diastolic dysfunction. (pitt.edu)
- Cardiac and vascular problems need investigation, lifstyle changes and sometimes specific medication. (abicana.com)
- Abstract We propose svMorph, a framework for interactive virtual sculpting of patient-specific vascular anatomic models. (nsf.gov)
- They are also compatible with popular vascular modeling software, such as SimVascular. (nsf.gov)
Arterial3
- This study describes a multidimensional 3D/lumped parameter (LP) model which contains appropriate inflow/outflow boundary conditions in order to model the entire human arterial trees. (sharif.edu)
- A new extensive LP model of the entire arterial network (48 arteries) was developed including the effect of vessel diameter tapering and the parameterization of resistance, conductor and inductor variables. (sharif.edu)
- Autoregulatory adaptation of the cardiac output and downstream arterial resistance was modeled in response to intervention‐induced hemodynamic perturbations. (nsf.gov)
Biomechanics4
- Department faculty members have teaching and research expertise in areas related to cardiovascular and fluid biomechanics, musculoskeletal biomechanics, biomaterials and tissue engineering, bioinstrumentation, biosystems, biomedical imaging, biological signal analysis, bioinformatics and computational biology, respiratory and pulmonary engineering, and other allied fields. (uiowa.edu)
- The Biomechanics and Biomaterials Laboratory is equipped to perform experiments relating to the cardiovascular and human musculoskeletal systems as well as the various properties of biomaterials. (uiowa.edu)
- The lab is used for the course BME:2500 Biomaterials and Biomechanics , elective courses in cardiovascular and musculoskeletal biomechanics, and senior design projects. (uiowa.edu)
- Miller, L., Penta, R. (2023) Investigating the effects of microstructural changes induced by myocardial infarction on the elastic parameters of the heart Biomechanics and Modeling in Mechanobiology, 22, pp. 1019-1033. (gla.ac.uk)
Boundary conditions2
- Wall, W.A. (2015) Pericardial Boundary Conditions for Cardiac Mechanics Simulations , 4th International Conference on Computational and Mathematical Biomedical Engineering - CMBE2015, P. Nithiarasu and E. Budyn (Eds. (tum.de)
- Realistic boundary conditions and Navier-Stokes equations in healthy and stenosed models of carotid artery bifurcation. (sharif.edu)
Simulation4
- Class tutorials deal about the application to cases belonging to the real clinical world, including the simulation of recent catheter-based, minimally invasive and reparative cardiovascular procedures. (polimi.it)
- In addition to basic and translational research, Dr. Shroff and colleagues have developed and continue to develop novel, simulation-based material (i.e., mathematical models of biological systems and associated "virtual experiments") for education and engineering design. (pitt.edu)
- Our tools can be applied separately or in combination to produce simulation-suitable morphed models. (nsf.gov)
- Abstract Researchers must decide on how they will model the non-linear material response in a Finite Element simulation to assess seismic vulnerability. (scielo.org)
Fluid1
- To illustrate our tools, we morph several image-based, patient-specific models to create a range of shape changes and simulate the resulting hemodynamics via three-dimensional, computational fluid dynamics. (nsf.gov)
Contraction1
- 1) Relationships between left ventricular mechano-energetic function and underlying cellular processes, with a special emphasis on contractile and regulatory proteins and post-translational regulation of cardiac contraction (e.g., via phosphorylation or acetylation). (pitt.edu)
Pulsatile1
- Brief review of lumped-parameter modelling and its use in pulsatile hydrodynamic design. (polimi.it)
20161
- Dr. Shroff has been serving as the Principal Investigator on a NIH-NHLBI pre-doctoral training grant (Cardiovascular Bioengineering Training Program) since 2005 and the Coulter Translational Research Partnership II Program since 2013, and Co-Director on a NIH-NHLBI post-doctoral training grant (Training Program in Imaging Sciences in Translational Cardiovascular Research) since 2016. (pitt.edu)
Finite1
- This paper aims at giving an insight into these modelling decisions by comparing Fiber and Lumped Plasticity Finite Element Models in static and dynamic non-linear analysis in a RC frame. (scielo.org)
Pulmonary1
- METHODS: An admission screening encounter consisted of collecting 2 swabs, to be tested by rt-PCR, and a data collection form for individuals admitted to ventilator units at 2 nursing homes (NHA and NHB), and the ventilator/pulmonary unit, intensive care unit, and cardiac care unit at a hospital (Hospital C) located in New York City from November 2017 to November 2019. (cdc.gov)
Mathematical1
- Mathematical Biology is the application of mathematical modelling to solve problems in biology and physiology. (gla.ac.uk)
Myocardial infarction1
- Aetna considers the use of chelation therapy experimental and investigational in the prevention and treatment of cancer, cardiovascular disease (e.g., atherosclerotic cardiovascular disease , coronary artery disease, individuals who had a myocardial infarction), neurodegenerative diseases (e.g. (aetna.com)
Computational models3
- Computational models of human physiology offer the potential, with clinical data, to create patient-specific models that capture a patient's physiological status. (springeropen.com)
- This article presents the concept of model-based therapeutics, the use of computational models in clinical medicine and critical care in specific, as well as its potential clinical advantages, in a format designed for the clinical perspective. (springeropen.com)
- The overall review clearly shows the concept and significant clinical potential of using computational models in critical care medicine. (springeropen.com)
Estimation1
- The proposed method of parameter estimation for hydraulic electric analogy model is recursive least squares algorithm. (sharif.edu)
Diseases2
- It is well known to reduce the risk of cardiovascular diseases and also avoid the risk of gaining weight. (autocityscotland.co.uk)
- Acute kidney injury (AKI) is a life-threatening disease with high mortality characterized by an abrupt decrease of the kidney glomerular filtration rate, extra-kidney consequences (cardiovascular diseases, lung injury, neurological impairment) and high risk of secondary chronic kidney disease (CKD). (hrb.ie)
Simulations2
- The course deals with the development and use of the latest engineering methods for high-fidelity simulations of surgical and interventional treatments of the cardiovascular system. (polimi.it)
- Large animal models and computer simulations indicate that adding non-contractile material to the damaged left ventricular wall can potentially reduce myofiber stress. (ucsf.edu)
Physiological2
- Physiological modeling, tight glycemic control, and the ICU clinician: what are models and how can they affect practice? (springeropen.com)
- Such models can provide new insights into patient condition by turning a series of sometimes confusing clinical data into a clear physiological picture. (springeropen.com)
System3
- Conventional models of cardiovascular system frequently lack required detail and focus primarily on the overall relationship between pressure, flow and volume. (sharif.edu)
- This study proposes a localized and regional model of the cardiovascular system. (sharif.edu)
- It is well known that the modern understanding of the cardiovascular system undoubtedly starts with the work of William Harvey (1578-1657) who published his discovery of the circulation of blood in 1628. (scirp.org)
Pump4
- In fact, although in the introduction to the problem (paragraphs 1-8), Euler focuses on the discussion on blood flow through arteries, to such a degree to even proposing adhoc models for the behavior of their elastic cross-sections, surprisingly, and also somehow disappointing, is that the main body of the manuscript (paragraphs 9-34) is devoted to the modeling of flows through rigid tubes, driven by a piston pump. (scirp.org)
- There are many possible configurations for a model of the pump, depending on the numbers of steps in the binding of Na or K and the places in the sequence of forms for the binding and release of ATP, ADP and Pi. (nih.gov)
- There are many different parameter sets saved within this JSim project file, modeling different conditions for a Sodium Potassium pump. (nih.gov)
- At the pump reversal potential, in the case of the "standard" concentrations for the model, this occurs at -200mV. (nih.gov)
Experiments1
- The use of experiments for validation of the models: analysis of real-world case studies. (polimi.it)
Elastic1
- frictional, elastic and hydraulic were considered for the prosthetic joints of the amputee and their design parameters were optimized to achieve the closest. (sharif.edu)
Predict2
- It utilizes noninvasive blood flow and pressure seed data and temporal cardiac muscle regional activity to predict the operation of the heart under normal and congestive heart failure conditions. (sharif.edu)
- Our study aims to model, assess, and predict hemodynamic outcomes of transcatheter interventions in these patients. (nsf.gov)
Methods3
- The aim of the course is to provide attendees with the knowledge needed to understand or design and implement computational and experimental models, and with an integrated vision, encompassing advanced experimental methods, advanced computational methods, and their combination. (polimi.it)
- A focus of this paper is that the model-based methods discussed here can provide patient-specific care that is robust to these intra- and inter-patient variabilities. (springeropen.com)
- Methods and Results Isolated proximal and "extensive" interventions (stenting and/or balloon angioplasty of proximal and lobar vessels) were performed in silico on 6 patient‐specific PA models. (nsf.gov)
Analysis2
- The use of models for interpreting experimental data: analysis of real-world case studies. (polimi.it)
- The results indicate that both models are in good agreement with the static analysis, and when considering Extensive and Complete Damage Limit States on the dynamic analysis. (scielo.org)
Design1
- A computer aided-design (CAD) algorithm was proposed to efficiently handle the coupling of two or more 3D models with the LP model, and substantially lessen the coupling processing time. (sharif.edu)
Clinical2
Areas1
- areas can change studied however for literary philosophers, and models can work them finally. (tavira-inn.com)
Results1
- When the model is run according to the parameters provided by Chapman et al, the curve displayed on this page results. (nih.gov)
Sets1
- Models numbered 5 and greater have the corresponding parameter sets saved within the .proj file (e.g. (nih.gov)
Body1
- Monounsaturated fats have a positive effect on overall health by improving body composition and reducing cardiovascular risks. (autocityscotland.co.uk)
Normal1
- A two-dimensional, seven link, nine degrees of freedom biped model was developed to investigate the dynamic characteristics of normal and transfemoral amputee locomotion during the entire gait cycle. (sharif.edu)
Input1
- These shape edits are performed via geometric operations on the surface mesh and vessel centerline curves of the input model. (nsf.gov)
Method1
- The equations of motion were derived using the Lagrange method and the stance foot-ground contact was simulated using a five-point penetration model. (sharif.edu)
Search1
- For a result to be included in the search result, is it required to fit all added including parameters (in at least one group) and not fit all parameters in one of the excluding groups. (diva-portal.org)
University1
- Working with a faculty steering committee, Dr. Hay led the redesign of the entire university budget away for historical budgeting to an RCM model. (arizona.edu)