• At the end of after 22 weeks, birthweight, congenital malformations, and this outbreak, seroprevalence was estimated to be 38.2% newborn admissions) were similar. (cdc.gov)
  • Prenatal exposure to arsenic is suspected to impair fetal health, including congenital malformations. (geus.dk)
  • In animal reproduction studies, administration during organogenesis resulted in decreased fetal weight and congenital malformations at maternal exposures 12 times higher than recommended human dose. (drugs.com)
  • Pregnancy registries have emerged as a rapid and systematic method to collect data that will provide information on whether an increased risk of major malformations exists with exposure to a particular medication compared to the baseline rate of major malformations in the general population. (womensmentalhealth.org)
  • Aim Children with congenital gastrointestinal malformations may be at risk of neurodevelopmental impairment due to challenges to the developing brain, including perioperative haemodynamic changes, exposure to anaesthetics and postoperative inflammatory influences. (bmj.com)
  • Standardised mean differences (Cohen's d) between cognitive, motor and language outcome of patients with congenital gastrointestinal malformations and normative data (39 studies) or the studies' control group (8 studies) were aggregated across studies using random-effects meta-analysis. (bmj.com)
  • Interpretation This study shows that children with congenital gastrointestinal malformations exhibit impairments in neurodevelopmental outcome, highlighting the need for routine screening of neurodevelopment during follow-up. (bmj.com)
  • Patients with non-cardiac congenital malformations are at risk of motor and cognitive impairment up to the age of 2 years. (bmj.com)
  • Patients with congenital gastrointestinal malformations have impaired neurodevelopmental outcome up to adolescence. (bmj.com)
  • In this article, enalapril exposures beyond the first trimester of pregnancy are associated with pre- and postnatal developmental disorders, such as reduced amniotic fluid volume (oligohydramnios), intrauterine growth restriction, congenital malformations secondary to oligohydramnios (retarded ossification of skull bones, limb positional deformities), fetal renal tubular pathology, neonatal renal failure, and early postnatal death. (epa.gov)
  • The present study searched for relationships between maternal alcohol consumption during pregnancy and the risk of congenital malformations. (bvsalud.org)
  • Physicians assessed for 6 major congenital malformations ( congenital heart defects [CHDs], male genital abnormalities , limb defects, cleft lip and/or cleft palate [orofacial clefts (OFC)], severe brain abnormalities , and gastrointestinal obstructions) up to 1 month after birth . (bvsalud.org)
  • There was no remarkable impact of maternal drinking habit status on the other congenital malformations after adjustment for covariates. (bvsalud.org)
  • Maternal alcohol consumption during pregnancy , even in early pregnancy , displayed no significant adverse impact on congenital malformations of interest. (bvsalud.org)
  • IMPACT This large-scale Japanese cohort study revealed that no teratogenic associations were found between maternal retrospective reports of periconceptional alcohol consumption and congenital malformations after adjustment for covariates. (bvsalud.org)
  • This is the first nationwide birth cohort study in Japan to assess the effect of maternal alcohol consumption during pregnancy on major congenital malformations. (bvsalud.org)
  • Dr Paganelli concludes: "(congenital malformations) "produced by Glyphosate Based Herbicides are mainly a consequence of the increase of endogenous retinoid activity. (nospray.org)
  • The congenital malformations observed include anencephaly, microcephaly, facial defects, myelomeningocele, cleft palate, ear malformations, polydactily, syndactily all consistent with the well-known and expected syndrome caused by upregulation of the Retinoic Acid pathway. (nospray.org)
  • Most studies have found no significant increase in major congenital malformations with antipsychotic medications [2, 3]. (ama-assn.org)
  • Untreated bipolar disorder and schizophrenia may be considered independent risk factors for congenital malformations, while SGAs were not associated with increased recurring defects in fetuses. (psychiatrist.com)
  • There were no congenital malformations (0%, 0/35). (karger.com)
  • Changing life styles, e.g. exposure of the mother to excessive alcohol, nicotine in tobacco smoke, easily available traditional and, over the counter medicines and environmental contaminants could be possible causes of congenital malformations. (nottingham.ac.uk)
  • Exposure to PAHs was assigned by industrial hygienist consensus, based on self-reported maternal occupational histories from 1 month before conception through the third month of pregnancy. (cdc.gov)
  • The suggested link between maternal exposure to Zika virus infection during the first trimester of pregnancy and the increased birth prevalence of microcephaly provide additional evidence for congenital infection with Zika virus. (cdc.gov)
  • Maternal weight and height, food frequency intake during pregnancy and haemoglobin levels were recorded for 594, 234 and 246 of the mothers respectively. (who.int)
  • Until 2015, with EU FP7 funding (led by Prof Helen Dolk), it focused on investigating medication safety in pregnancy and risk of congenital anomalies. (ulster.ac.uk)
  • Since 2019, the consortium joined the Innovative Medicines Initiative (IMI) funded ConcePTION project, to further research maternal disease and maternal medication exposures during pregnancy and expanding outcomes to include child neuro-developmental outcomes. (ulster.ac.uk)
  • Through the project Ulster has established the Global Birth Defects initiative, in addition to developing the innovative Global Birth Defects App, both of which are aimed at providing resources for birth defects surveillance in low resource environments globally, particularly in relation to exposures to medications (e.g. antiretrovirals) and infections in pregnancy. (ulster.ac.uk)
  • A pregnancy exposure registry is available. (drugs.com)
  • If countries have the capacity to identify risk factors associated with congenital anomalies such as maternal exposures (e.g., use of medications during the first trimester), a pregnancy registry or a case- control study can be implemented to allow for the collection of exposure data during pregnancy. (cdc.gov)
  • Neurological defects followed exposure to primary maternal infection in all three trimesters of pregnancy and also recurrent maternal infection. (bmj.com)
  • All live births to women aged 15-45 years were identified over a 6 year period (2001-2007) from 11 US health plans participating in the Medication Exposure in Pregnancy Risk Evaluation Program. (womensmentalhealth.org)
  • In addition, the Registry also collects information on maternal and infant health outcomes associated with use of atypical antipsychotics during pregnancy. (womensmentalhealth.org)
  • 2 , 3 Many factors are associated with increased risk of developmental delay, including poor maternal health during pregnancy, birth complications, infections, genetic characteristics, exposure to toxins, trauma, maltreatment and possibly low socioeconomic status. (cmaj.ca)
  • Potential risk factors that have been studied include exposure to certain chemicals or drugs before birth, viral infections (such as rubella and influenza) that occur during pregnancy, and other maternal illnesses including diabetes and phenylketonuria . (medlineplus.gov)
  • Sun exposure is an important environmental variable that has risks and benefits for human health, but the effects of sun exposure on pregnancy duration and preterm birth are unknown. (frontiersin.org)
  • Increased available sun exposure in the first trimester of pregnancy was associated with a reduced risk of preterm birth, with evidence of a dose-response. (frontiersin.org)
  • However, sun exposure in pregnancy remains mainly incidental and unconsidered. (frontiersin.org)
  • Although there have been relatively few studies, a systematic review of sun exposure and pregnancy outcomes found associations with fetal growth restriction, blood pressure, and preterm birth rates ( 7 , 8 ), with higher first trimester sunlight correlating with higher fetal birth weights and less hypertensive complications in the third trimester ( 8 ). (frontiersin.org)
  • Multiple logistic regression analysis was performed to identify associations between maternal alcohol consumption during pregnancy and each malformation. (bvsalud.org)
  • The prevalence of maternal drinking in early pregnancy and until the second/ third trimester was 46.6% and 2.8%, respectively. (bvsalud.org)
  • Our finding indicated that maternal low-to-moderate alcohol consumption during pregnancy , even in early pregnancy , displayed no significant adverse impact on congenital heart defects , male genital abnormalities , limb defects, orofacial clefts, severe brain abnormalities , or gastrointestinal obstructions. (bvsalud.org)
  • A spontaneous abortion or termination following varicella infection during pregnancy with ultrasonographic findings 3 or pathological findings compatible with congenital varicella syndrome. (bccdc.ca)
  • maternal infection with the Zika virus during the third trimester of pregnancy is not linked to structural abnormalities in the fetus. (nospray.org)
  • Both bipolar disorder and schizophrenia were linked to a slightly increased risk of obstetric complications for mothers (schizophrenia) and the newborn (bipolar disorder and schizophrenia), although data on drug exposure during pregnancy were not given in the majority of studies. (psychiatrist.com)
  • In early 1961 doctors noticed an extraordinary increase in documented cases of children with a verity of birth defects, and they soon hypothesized that maternal exposure to Thalidomide during pregnancy caused these often-severe congenital abnormalities. (asu.edu)
  • The duration of exposure in utero is a major determinant of foetal transmission and late treatment in pregnancy may not be effective against congenital disease [ 13 ]. (biomedcentral.com)
  • 4 , 5 , 6 Owing to these harmful effects, malaria in pregnancy is a significant driver of maternal and neonatal health in endemic areas. (glowm.com)
  • Alcohol consumption and tobacco exposure during pregnancy are hazardous behaviours which are increasing significantly in low and middle-income countries, including sub-Saharan Africa. (springer.com)
  • This is a part of a prospective cohort study among pregnant women in Ibadan, Nigeria (Ibadan Pregnancy Cohort Study (IbPCS), which investigated the associations between maternal obesity, lifestyle characteristics and perinatal outcomes in Ibadan. (springer.com)
  • The prevalence of tobacco exposure in the index pregnancy was 64 (3.7%), i.e. one in every 27 pregnancies is exposed to tobacco. (springer.com)
  • 95% CI: 4.93, 34.03) of tobacco exposure during pregnancy in our study population. (springer.com)
  • The most burdensome of its complications is the Fetal Alcohol Spectrum Disorder (FASD), a cluster of lifelong medical conditions of varying severity caused by feotal exposure to alcohol during pregnancy [ 7 , 8 , 9 ]. (springer.com)
  • Furthermore, the transgenerational effect of prenatal alcohol exposure has been reported with each episode of drinking during pregnancy exposing three generations, i.e. mother, fetus and fetal germline, to its hazardous effects [ 13 ]. (springer.com)
  • The Organization of Teratology Information Specialists is a network of risk-assessment counselors in the United States and Canada who specialize in researching and communicating the risks associated with drug exposures in pregnancy. (medscape.com)
  • When acquired during pregnancy, toxoplasmosis often goes unrecognized in the mother, but it can produce a severe congenital infection with ocular and neurologic damage to the infant. (glowm.com)
  • This systematic review evaluates maternal tolerance and obstetric and perinatal outcomes following sildenafil citrate (SC) use in human pregnancy. (karger.com)
  • Also, mother's exposure to viruses 'particularly during early period of pregnancy.In child factors, it was found that children with genetic problems particularly that is associated with chromosomal anomalies are more vulnerable to have congenital heart diseases. (badralsamaahospitals.com)
  • Stratified analyses were performed for septal defects according to maternal age, pre-pregnancy body mass index, and maternal race/ethnicity. (radygenomics.org)
  • Congenital transmission can occur when a woman is infected with Toxoplasma gondii during, or just before, pregnancy. (blogspot.com)
  • Exposure was defined as any maternal use of loratadine from 1 month before pregnancy through the first trimester. (cdc.gov)
  • The influence of maternal body mass index, maternal diabetes mellitus, and maternal smoking during pregnancy on the risk of childhood‐onset type 1 diabetes mellitus in the offspring: Systematic review and meta‐analysis of observational studies. (ivoryresearch.com)
  • The presence of a congenital anomaly is associated with increased childhood cancer risk, likely due to large effects of Down syndrome and chromosomal anomalies for leukemia. (plos.org)
  • Congenital anomalies were assessed from birth records and diagnosis codes in linked hospital discharge data. (plos.org)
  • Congenital anomalies (i.e., birth defects) are one of the strongest and most consistent risk factors for childhood cancer. (plos.org)
  • CONTEXT: The association between prenatal cocaine exposure and congenital anomalies is not definitive. (erowid.org)
  • CONCLUSIONS: This prospective, large-scale, blinded, systematic evaluation for congenital anomalies in prenatally cocaine-exposed children did not identify an increased number or consistent pattern of abnormalities. (erowid.org)
  • Dr Maria Loane leads the study assessing risk of neurodevelopmental outcomes and congenital anomalies associated with maternal exposure to antidepressants. (ulster.ac.uk)
  • EUROlinkCAT is a H2020 funded project involving UU and 21 other partners which is investigating the mortality, morbidity and educational outcomes for children born with congenital anomalies 1995-2014. (ulster.ac.uk)
  • Currently, the accuracy of fetal echocardiography enables the detailed diagnosis of a significant variety of congenital cardiac anomalies, and it has also been demonstrated that prenatal outcomes may improve in critical CHDs. (benthamscience.com)
  • The chapter also discusses the parental counseling and fetal and neonatal therapeutic management of such congenital cardiac anomalies. (benthamscience.com)
  • Congenital anomalies , also known as birth defects, are structural or functional abnormalities, including metabolic disorders, which are present from birth. (cdc.gov)
  • This manual is intended to serve as a tool for the development, implementation and ongoing improvement of a congenital anomalies surveillance programme, particularly for countries with limited resources. (cdc.gov)
  • This manual provides selected examples of congenital anomalies (see Appendix A ). Typically, these anomalies are severe enough that they would probably be captured during the first few days following birth. (cdc.gov)
  • Nevertheless, these are just suggestions, and countries can choose to monitor a subset of these conditions or add other congenital anomalies to meet their needs. (cdc.gov)
  • understand how to calculate the prevalence of congenital anomalies. (cdc.gov)
  • Surveillance of congenital anomalies should be ongoing and should involve a systematic review of birth outcomes to determine the presence of congenital anomalies. (cdc.gov)
  • This manual is intended to facilitate the collection of essential information for the purpose of assessing the burden of congenital anomalies. (cdc.gov)
  • It must be noted that the manual does not present specific information on how to collect risk factor information or how to manage a neonate born with congenital anomalies. (cdc.gov)
  • Surveillance of Congenital Anomalies 1. (cdc.gov)
  • Around 40 registries submitted data on 39 congenital anomalies for this report. (healthdata.org)
  • Despite limited data, overall there does not appear to be any severe adverse maternal side effects nor any increase in the rate of stillbirths, neonatal deaths, or congenital anomalies attributed to SC. (karger.com)
  • 0.5 μg/L, 0.5-0.9 μg/L, 1.0-4.9 μg/L, ≥5.0 μg/L). Outcomes were defined as congenital heart disease diagnosed within the first year of life, with sub-categorization of severe, septal defects and valvular heart defect. (geus.dk)
  • There was no relationship between amount or timing of exposure and any of the outcomes. (erowid.org)
  • In this study we investigated whether these joint introductions of tobacco control policies in the Netherlands were associated with changes in key perinatal outcomes known to be associated with maternal smoking and/or SHS exposure. (nature.com)
  • This is a highly innovative global outreach project demonstrating inroads to improved public health outcomes from the implementation of culturally relevant and specifically targeted maternal health education programmes in Myanmar. (ulster.ac.uk)
  • The UK Prevention Research Partnership (UKPRP) - Maternal and Child Health Network (MatchNet) brings together six collaborative UK-based academic institutions, including Ulster, with a view to capitalizing on linked, population-level administrative data and variations in policy across the four nations to assess interventions on and determinants of adverse child outcomes. (ulster.ac.uk)
  • in the September, 2011 edition of Neuropsychopharmacology examining the relationship between exposure to selective serotonin reuptake inhibitor drugs (SSRIs) and adverse birth outcomes . (dangerousdrugs.us)
  • Few reviews have synthesized the associations between dietary pesticide exposure and health outcomes in. (biomedcentral.com)
  • However, no systematic studies on the relationship between the adverse outcomes and enalapril gestational exposures are available. (epa.gov)
  • and (2) To examine the relationship between the reported adverse outcomes and prenatal enalapril exposure, taking timing and duration of exposure into account, as well as several other factors that could confound any observed association between exposure and outcome. (epa.gov)
  • Maternal morbidity (schizophrenia but not bipolar disorder) may be associated with the worst neonatal outcomes (stillbirth, neonatal or infant deaths, and intellectual disability). (psychiatrist.com)
  • RESULTS: The prevalence of occupational PAH exposure was 4.0% in CHD case mothers (76/1907) and 3.6% in control mothers (104/2853). (cdc.gov)
  • For CHD phenotypic subtypes in which modest nonsignificant associations were observed, future investigations could be improved by studying populations with a higher prevalence of PAH exposure and by incorporating information on maternal and fetal genotypes related to PAH metabolism. (cdc.gov)
  • Background: Previous studies have reported positive associations between maternal exposure to and the prevalence of NTDs in offspring. (cdc.gov)
  • Controls were frequency matched to cases by the central nervous system that result from ciations between maternal exposures to air year of birth because of the decreasing birth failure of neural tube closure (Christianson pollutants other than HAPs (i.e., criteria pol- prevalence of NTDs over time (Canfield et al. (cdc.gov)
  • The prevalence, pattern and predictors of alcohol consumption and tobacco exposure among pregnant women in Ibadan, Nigeria, were investigated. (springer.com)
  • The mean birthweight, gestational age, and head circumference of children with congenital cytomegalovirus infection were not significantly different from those of controls. (bmj.com)
  • 2019), the researchers noted a correlation between being overweight and maternal obesity and maternal gestational weight gain. (ivoryresearch.com)
  • Therefore, we conducted a case-control study assessing the association between estimated maternal occupational exposure to PAHs and CHDs in offspring. (cdc.gov)
  • CONCLUSIONS: Our findings do not support an association between potential maternal occupational exposure to PAHs and various CHDs in a large, population-based study. (cdc.gov)
  • Congenital heart diseases (CHDs) are largely known as an important cause of fetal perinatal mortality. (benthamscience.com)
  • Congenital Heart Diseases (CHDs) contribute for about 1% of total newborn deliveries which means in every 100 new deliveries, there is one newborn that will have congenital heart diseases. (badralsamaahospitals.com)
  • OBJECTIVES: To assess associations between maternal smoking and congenital heart defects (CHDs) in offspring. (radygenomics.org)
  • Estimates based on these findings suggest that the impact of congenital cytomegalovirus infection is comparable to that of congenital rubella in the era before vaccination. (bmj.com)
  • When this transmission of crucial genes is disrupted, it can increase the risk of birth defects, such as congenital rubella and thalidomide exposure. (earth.com)
  • Maternal viral infection with rubella or cytomegalovirus have been known to cause fetal malformation and fetal demise. (nospray.org)
  • Previous research uncovered a link between maternal heat exposure and the risk of heart defects. (albany.edu)
  • This literature review analyzes recent publications to determine the link between maternal smoking and childhood obesity. (ivoryresearch.com)
  • A 1962 study titled "Thalidomide and Congenital Abnormalities," by Victor Knapp, George Christie, and Mary Seller, all working in the UK, looked at the teratogenic effects of Thalidomide on rats, mice, and rabbits, and the study reported no abnormalities in the offspring of these animals after researchers had exposed the pregnant females to the drug. (asu.edu)
  • In humans limb truncation in offspring is a common congenital abnormality arising from Thalidomide use by pregnant women. (asu.edu)
  • What are some of the primary causes of congenital heart disease? (parkview.com)
  • The OR was also higher for severe congenital heart disease but at the same level among all exposure levels ≥0.5 μg/L. The OR of congenital valvular heart defects was only higher among children with maternal exposure to arsenic in drinking water ≥5.0 μg/L. The associations were similar for boys and girls. (geus.dk)
  • and open heart surgery for severe congenital heart disease. (bengalurukidsortho.in)
  • Approximately 1 to 2 cases of congenital toxoplasma occur per 10,000 children born. (glowm.com)
  • Our goal was to determine the rate of clinically identified cases of congenital toxoplasmosis in children from birth to 2 years of age within the Northern California Kaiser Permanente Medical Care Program (KPNC) during a 15-year period. (blogspot.com)
  • After electronic and paper charts were reviewed, 2 cases of congenital toxoplasmosis were confirmed. (blogspot.com)
  • Exceptions to this may include patients with congenital RRP who have been exposed in utero and adult patients who may have been exposed during sexual contact. (nih.gov)
  • Maternal alcohol consumption and risk of offspring with congenital malformation: the Japan Environment and Children's Study. (bvsalud.org)
  • Congenital cytomegalovirus infection. (bmj.com)
  • Clinical details of 50 infants with congenital cytomegalovirus infection identified in a prospective study are reported. (bmj.com)
  • 80-81) Of 50 babies reported with microcephaly, only four (8 %) had laboratory evidence of congenital Zika virus infection on RT-PCR. (nospray.org)
  • The risk of microcephaly after maternal infection is estimated at roughly one in 100 women… This is a relatively low risk compared with other causal infections such as cytomegalovirus . (nospray.org)
  • Fetal infection occurs only during the acute phase of infection, when T. gondii in maternal blood are transported to the placenta and fetus. (glowm.com)
  • Antibody formation elicited in response to the parasite converts the parasite from the trophozoite to the tissue cyst form, and the parasite no longer circulates in blood to cause congenital infection. (glowm.com)
  • Infection usually occurs by ingestion of undercooked meat and unwashed fruits and vegetables or exposure to soil or water contaminated with cat feces. (blogspot.com)
  • Infants were excluded if they had 1) known or suspected chromosome abnormalities, 2) single gene conditions, or 3) other recognized multiple congenital anomaly phenotypes. (cdc.gov)
  • NBDPS is an ongoing, multistate, case-control study of environmental and genetic risk factors for major birth defects that can be used in response to public health concerns regarding rare drug exposures and birth defects ( 3,4 ). (cdc.gov)
  • Some syndromes and chromosomal abnormalities could also cause congenital heart disease, so knowing your family history is vital. (parkview.com)
  • Numerous related issues--such as the epidemiologic workup of infectious disease outbreaks, the assessment of the health effects of environmental exposures, the prospective detection of clusters, and the investigation of interpersonal networks--are not addressed. (cdc.gov)
  • Another study in the journal examined how dysregulation and maternal diabetes affect cardiac development and the important signaling pathways in an embryo. (earth.com)
  • For example, some congenital heart defects are associated with maternal diabetes. (parkview.com)
  • Maternal diseases like diabetes mellitus are also one of the etiological factors for developmental defects. (nottingham.ac.uk)
  • Researches have shown that pregnant women with diabetes will have 5 times more chances to have a child with associated diseases and also congenital heart diseases. (badralsamaahospitals.com)
  • To determine whether prenatal cocaine exposure results in an increased number or identifiable pattern of abnormalities. (erowid.org)
  • the OR was 1.13 (95% CI: 1.08-1.19) for exposure of 0.5-0.9 μg/L, 1.33 (95% CI: 1.27-1.39) for 1.0-4.9 μg/L and 1.42 (95% CI: 1.24-1.63) for ≥5.0 μg/L. Similar associations were observed for congenital septal defects. (geus.dk)
  • the risk for septal defects is modified by maternal age. (radygenomics.org)
  • ALBANY, N.Y. (Feb. 19, 2019) - A School of Public Health professor and her postdoctoral fellow are making national headlines for their research finding that climate change could increase the number of U.S. infants born with congenital heart defects. (albany.edu)
  • Among the 1,957 mothers of infants in the case and control populations, 33 (1.7%) reported using loratadine during the exposure period. (cdc.gov)
  • Logistic regression was used to evaluate the association between maternal occupational PAH exposure and specific CHD phenotypic subtypes among offspring. (cdc.gov)
  • Few studies investigated an association between maternal exposure to arsenic and congenital heart disease. (geus.dk)
  • To examine the association between maternal exposure to arsenic through drinking water and congenital heart disease among offspring. (geus.dk)
  • Objective: To examine the association between maternal exposure to arsenic through drinking water and congenital heart disease among offspring.Methods: This nationwide cohort study included all liveborn children in Denmark, 1997-2014. (geus.dk)
  • No association was seen between preterm birth and second trimester available sun exposure or combined first and second trimester exposure. (frontiersin.org)
  • However, the US Food and Drug Administration issued a warning regarding the potential risk of abnormal muscle tone and withdrawal symptoms to newborns with exposure to antipsychotics during the third trimester [4]. (ama-assn.org)
  • Maternal occupational exposure to polycyclic aromatic hydrocarbons and congenital heart defects among offspring in the National Birth Defects Prevention Study. (cdc.gov)
  • However, it can also be associated with certain genetic or congenital (present from birth) disorders. (medlineplus.gov)
  • Associations between arsenic levels and congenital heart disease were analysed using logistic regression, presented as odds ratios (OR) with 95% confidence interval (CI), and adjusted for year of birth, mother's educational level and ethnicity. (geus.dk)
  • This study in Egypt investigated the influence of selected maternal factors on neonatal birth size. (who.int)
  • A significant positive correlation between maternal anthropometric variables with neonatal birth dimensions was observed and the effect was more evident in girls than boys for BMI and head circumference. (who.int)
  • Statistically significant negative correlations were found between maternal haemoglobin levels and birth size. (who.int)
  • Birth size was strongly correlated with maternal consumption of micronutrient-rich food at all stages of gestation. (who.int)
  • Critical congenital heart disease (CCHD) is a term that refers to a group of serious heart defects that are present from birth. (medlineplus.gov)
  • To determine the association between available sun exposure and preterm birth. (frontiersin.org)
  • Researchers are still learning about how the maternal environment and nursing impacts early development, and a new issue in the journal Birth Defects Research focuses on this complex relationship. (earth.com)
  • The interactions between the maternal environment and offspring genes are hyper-complex, but studying them may suggest incredible opportunities to prevent diseases that are notoriously hard to treat after the fact," said Patrick Jay, the co-editor of the new Birth Defects issue. (earth.com)
  • Additional risks of untreated maternal psychosis to the child include premature birth, low birth weight, and fetal demise [1]. (ama-assn.org)
  • If we break it down, congenital means 'from birth. (parkview.com)
  • They are also the leading causes of preventable congenital and birth defects in western countries [ 7 ]. (springer.com)
  • Congenital heart defects are responsible for more neonatal deaths than any other birth defect. (nottingham.ac.uk)
  • Potential confounding factors tested by multivariate logistic regression analysis included maternal age, maternal race/ethnicity (i.e., non-Hispanic white, non-Hispanic black, Hispanic, and other), birth month, and state of residence at delivery. (cdc.gov)
  • 2017). According to the findings of this study, the habit is linked to low birth weight, congenital disabilities of the lip and mouth, premature birth, besides increasing the risk of infant death syndrome. (ivoryresearch.com)
  • The most prevalent effect of smoking being low birth weight, congenital disabilities of the lip and mouth and premature births. (ivoryresearch.com)
  • The association between fetal exposure to alcohol and congenital structural disorders remains inconclusive. (bvsalud.org)
  • Alcohol consumption and tobacco exposure of 1745 pregnant women were assessed during enrollment by self-reports using an interviewer-administered questionnaire. (springer.com)
  • Alcohol consumption and tobacco exposure are not uncommon and have been an ongoing but neglected threat to maternal and child health in Nigeria. (springer.com)
  • maternal exposure, neural tube defects. (cdc.gov)
  • Pregnant women who resided at Camp Lejeune during the contamination period are of particular concern, as studies have shown that maternal exposure to contaminated water has led to a higher incidence of neural tube congenital disabilities, such as spina bifida. (advocacyforpatients.org)
  • Supplementation with micronutrients such as folic acid and Vitamin C during the periconceptional period has been shown to prevent some neural tube and congenital heart defects. (nottingham.ac.uk)
  • As these kinds of health effects data become available and methods to assess levels of significant human exposure improve, these MRLs will be revised. (cdc.gov)
  • it is also associated with increased maternal and neonatal and infant mortality through both direct and indirect mechanisms. (glowm.com)
  • There were no infant deaths for which congenital toxoplasmosis was recorded as a cause. (blogspot.com)
  • Since 92% of microcephaly babies are not caused by maternal Zika virus, perhaps we should be looking for other preventable causes. (nospray.org)
  • Disturbed development of the enteric nervous system after in utero exposure of selective serotonin re-uptake inhibitors and tricyclic antidepressants. (dangerousdrugs.us)
  • The reviews in the issue present the latest about what scientists and physicians have learned about maternal influences on the baby in utero. (earth.com)
  • Having any congenital anomaly was associated with an increased risk of childhood cancer (OR: 1.46, 95% CI 1.28-1.65). (plos.org)
  • If an ounce of prevention is worth a pound of cure for one disease, targeting adverse maternal effects in the womb could be worth a ton for future public health. (earth.com)
  • In many instances, the health agency will not be able to demonstrate an excess of the condition in question or establish an etiologic linkage to an exposure. (cdc.gov)
  • When an excess is confirmed, the likelihood of establishing a definitive cause-and-effect relationship between the health event and an exposure is slight. (cdc.gov)
  • The primary purpose of this chapter is to provide public health officials, physicians, toxicologists, and other interested individuals and groups with an overall perspective of the toxicology of thallium and a depiction of significant exposure levels associated with various adverse health effects. (cdc.gov)
  • These distinctions are intended to help the users of the document identify the levels of exposure at which adverse health effects start to appear. (cdc.gov)
  • Public health officials and project managers concerned with appropriate actions to take at hazardous waste sites may want information on levels of exposure associated with more subtle effects in humans or animals (LOAEL) or exposure levels below which no adverse effects (NOAEL) have been observed. (cdc.gov)
  • Through reducing maternal smoking and SHS exposure, tobacco control policies have considerable potential to benefit perinatal health. (nature.com)
  • Research on the effect of pesticide exposure on health has been largely focused on occupational settings. (biomedcentral.com)
  • Prenatal exposure to both atypical and typical antipsychotics was ascertained from health plan pharmacy dispensing files. (womensmentalhealth.org)
  • Maternal and child health journal. (healthpartners.com)
  • However, they have received little attention in Nigeria's maternal health research and services. (springer.com)
  • Maternal smoking is a major public health concern with well-known consequences to both the newborn and the mother. (ivoryresearch.com)
  • The maternal health status has also been pointed out as one of the contributing factors. (ivoryresearch.com)
  • that appeared in the February, 2013 edition of Prescrire International examines additional risks of prenatal exposure to selective serotonin reuptake inhibitor drugs (SSRIs) . (dangerousdrugs.us)
  • For some individuals, the signs and symptoms of congenital heart disease, like a murmur or arrhythmia, may go unnoticed until adulthood. (parkview.com)
  • Signs and Symptoms of Congenital Heart Diseases. (badralsamaahospitals.com)
  • Estimates of exposure levels posing minimal risk to humans (MRLs) have been made, where data were believed reliable, for the most sensitive noncancer effect for each exposure duration. (cdc.gov)
  • No studies were located regarding lethality in humans or animals after inhalation exposure to thallium. (cdc.gov)
  • No studies were located in humans or animals regarding the effects on the respiratory, hematological, musculoskeletal, hepatic, renal, and dermal/ocular systems after inhalation exposure to thallium. (cdc.gov)
  • A total of 1,042,413 liveborn children were included of whom 1.0% had a congenital heart disease. (geus.dk)
  • Early life exposure to lead, mercury, polychlorinated biphenyls (PCBs), polybromide diphenyl ethers (PBDEs), organophosphate pesticides (OPPs), and phthalates have been associated with lowered IQ in children. (biomedcentral.com)
  • Although cesarean section may prevent the exposure of children to the HPV virus during childbirth, its effectiveness in preventing RRP is debatable and the procedure itself carries an increased risk of complications. (nih.gov)
  • A cardiologist explains congenital heart disease and shares some common causes, symptoms, and strategies for diagnosis in children and adults. (parkview.com)
  • Can children outgrow a congenital heart defect or condition? (parkview.com)
  • For example, at the age of 1 year normal children should be 10kg but children with congenital heart diseases usually have lesser weight compared to normal children. (badralsamaahospitals.com)
  • Children with Down, William and Turner syndrome usually have more chances to have congenital heart diseases. (badralsamaahospitals.com)
  • This investigation showed that exposure to smoking during or postnatal was significantly associated with being overweight for children aged seven years. (ivoryresearch.com)
  • Maternal smoking and risk of obesity in school children: Investigating early life theory from the GRECO study. (ivoryresearch.com)
  • Dr. Jeffrey Dach: Is it Zika Virus or Glyphosate Exposure? (nospray.org)
  • Types of Congenital Heart Diseases. (badralsamaahospitals.com)
  • It causes bluish discoloration and contributes for almost 30% of total congenital heart diseases and is usually complex and associated with Hypoplasia (incomplete development) of one or more chambers of the heart or may absence of one of the main valve in the heart. (badralsamaahospitals.com)
  • It doesn't cause bluish discoloration and contribute for almost 70% of congenital heart diseases. (badralsamaahospitals.com)
  • What Causes Congenital Heart Diseases? (badralsamaahospitals.com)
  • Additionally, exposure to radiation was found to increase risk of congenital heart diseases. (badralsamaahospitals.com)
  • Diagnosis of Congenital Heart Diseases. (badralsamaahospitals.com)
  • Most of the times we need to use echocardiography to diagnosis congenital heart diseases and it can help most of the times to establish the diagnosis. (badralsamaahospitals.com)
  • Most of congenital heart diseases do not require any treatment except follow up. (badralsamaahospitals.com)