• In males with CAH, 11-oxygenated androgen levels may indicate the presence testicular adrenal rest tumors. (wikipedia.org)
  • While studies suggest that 11β-OHP, also known as 21-deoxycorticosterone, can be used as marker for adrenal 21-hydroxylase deficiency, another 21-carbon steroid - 21-deoxycortisol (produced from 17α-hydroxyprogesterone) gained acceptance for this purpose. (wikipedia.org)
  • 7) The LPS-low group, LPS-mid group, and LPS-high group showed an increase in HYP content and α-SMA expression in the lung tissue of rats. (alljournal.ac.cn)
  • It is linked, by an insufficiently described mechanism, to primary adrenal insufficiency (PAI) with or without mineralocorticoid insufficiency and several extra-adrenal manifestations (i.e. gonadal adrenal rest tumors, cardiomyopathy, hypothyroidism, and precocious puberty). (eurospe.org)
  • We tested the hypothesis that multiple alterations in the metabolism of glucocorticoids are required for the development of hypertension in children who become overweight.Methods: Timed spot urine for targeted gas chromatography-mass spectrometry steroid metabolome analysis was collected from (1) overweight/hyp. (eurospe.org)