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Transplantation, AutologousLiver TransplantationTransplantation, HomologousBone Marrow TransplantationKidney TransplantationHematopoietic Stem Cell TransplantationHeart TransplantationStem Cell TransplantationLung TransplantationTransplantation ConditioningGraft SurvivalOrgan TransplantationBlood Transfusion, AutologousGraft RejectionCell TransplantationPancreas TransplantationIslets of Langerhans TransplantationTissue DonorsTransplantation ImmunologyTransplantationTreatment OutcomeTransplantation ChimeraGraft vs Host DiseaseImmunosuppressive AgentsPeripheral Blood Stem Cell TransplantationTransplantation, IsogeneicLiving DonorsTransplantation, HeterotopicCord Blood Stem Cell TransplantationTime FactorsHeart-Lung TransplantationRetrospective StudiesCombined Modality TherapyRecurrenceImmunosuppressionTransplantation ToleranceTissue and Organ ProcurementHistocompatibility TestingWhole-Body IrradiationSkin TransplantationLiver FailureFetal Tissue TransplantationPostoperative ComplicationsMesenchymal Stem Cell TransplantationHematologic NeoplasmsFollow-Up StudiesMelphalanSurvival AnalysisTransplantation, HeterologousTissue TransplantationSurvival RateCyclophosphamideRemission InductionMultiple MyelomaWaiting ListsHistocompatibilityCorneal TransplantationBusulfanCyclosporineT-LymphocytesTacrolimusLymphoma, Non-HodgkinAntineoplastic Combined Chemotherapy ProtocolsBone Marrow PurgingCadaverHLA AntigensDisease-Free SurvivalHematopoietic Stem CellsHematopoietic Stem Cell MobilizationLeukemiaCarmustineBrain Tissue TransplantationMyeloablative AgonistsLiver DiseasesSalvage TherapyFacial TransplantationOrgan PreservationAntigens, CD34Donor SelectionTransplantsHodgkin DiseaseCells, CulturedPrognosisAcute DiseaseAntilymphocyte SerumEtoposideLymphocyte Culture Test, MixedRisk FactorsTissue and Organ HarvestingProspective StudiesLeukemia, Myeloid, AcuteBone Marrow CellsKidney Failure, ChronicAnemia, AplasticGranulocyte Colony-Stimulating FactorCytotoxicity, ImmunologicCell DifferentiationCytomegalovirus InfectionsLymphocyte ActivationCytarabine
Hematopoietic cellCell transplantationMesenchymal stemBone marrow derivedAbstractChondrocyte transplantationASCTChemotherapy with autologousAllogeneic transplantationEfficacyPeripheral bloodLymphomaOutcomeProgenitor cellsTransplantMarrow transplantationPatientsSurvivalWeeks after transplantationLimbalTissueAcute myeloidOutcomesInjectionsStem cellTransplantsCentersPostoperativeUnderwentCellsTreatmentIPSCsAutogenousImplantationRelapseResultsInjectionTherapiesVersusMortalityFindingsMembraneCartilage
Hematopoietic cell8
  • Late mortality in survivors of autologous hematopoietic-cell transplantation: report from the Bone Marrow Transplant Survivor Study. (qxmd.com)
  • We assessed late mortality in 854 individuals who had survived 2 or more years after autologous hematopoietic cell transplantation (HCT) for hematologic malignancies. (qxmd.com)
  • Introduction: In the United States, autologous hematopoietic cell transplantation (autoHCT) has fallen out of favor over chemotherapy consolidation for non-high-risk acute myeloid leukemia (AML) when allogeneic hematopoietic cell transplantation (alloHCT) is unfeasible, which is common in racial minorities because of donor registry under-representation and socioeconomic challenges. (elsevierpure.com)
  • Background For patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL), autologous hematopoietic cell transplantation (auto-HCT) is commonly used. (northwestern.edu)
  • Quality of Life after Allogeneic Hematopoietic Cell Transplantation" by Joseph Pidala, Claudio Anasetti et al. (usf.edu)
  • High-dose therapy with allogeneic hematopoietic cell transplantation (HCT) offers effective control and potential cure of hematopoietic malignancies, but with the cost of associated morbidity that includes adverse effects on quality of life (QOL). (usf.edu)
  • The specific medications administered depend on the choice of therapy and whether it is supportive care only, immunosuppressive therapy, or hematopoietic cell transplantation. (medscape.com)
  • Central venous catheter placement is required before the administration of hematopoietic cell transplantation. (medscape.com)
Cell transplantation32
Mesenchymal stem2
  • Because mesenchymal stem cells may regenerate cartilage, cartilage growth in human knees using autologous cultured mesenchymal stem cells is under research and preliminary clinical use, and appears to be safe as of 2016. (wikipedia.org)
  • The recent emergence of cell-based therapies such as autologous bone marrow-derived mesenchymal stem cells (ABM-MSCs) and mononuclear cells (ABM-MNCs) seems to offer a pragmatic approach to augment β-cell function/mass. (drcalapai.com)
Bone marrow derived3
Abstract1
  • Abstract Introduction: Graft-versus-host disease (GVHD) is a serious complication in allogeneic transplantation. (scielo.org)
Chondrocyte transplantation2
  • One cell-based replacement technique is called autologous chondrocyte implantation (ACI) or autologous chondrocyte transplantation (ACT). (wikipedia.org)
  • Membrane-assisted autologous chondrocyte transplantation is considered the gold standard surgical technique to treat greater than two millimetres diameter cartilage lesions in the knee in patients after conservative treatment failure. (ijclinicaltrials.com)
ASCT4
  • High-dose chemotherapy with autologous stem-cell rescue (HDC/ASCT) is the best salvage therapy for patients with aggressive B-cell lymphomas. (cun.es)
  • In conclusion, long survival times can be achieved in patients with AL amyloidosis treated with HDM/ASCT, also in smaller centres. (lu.se)
  • CONCLUSIONS: Conditioning with CBV or BEAM and subsequent ASCT was feasible and effective. (smw.ch)
  • Both MDSC phenotypes pre-ASCT but not post-ASCT similarly suppressed in vitro autologous T and natural killer T cell proliferation. (biomedcentral.com)
Chemotherapy with autologous1
  • High-dose chemotherapy with autologous bone marrow transplantation: 11 years' experience in Zurich. (smw.ch)
Allogeneic transplantation1
  • We compared outcomes of consolidation strategies in a minority-rich cohort in the Bronx with limited access to allogeneic transplantation. (elsevierpure.com)
Efficacy3
  • This randomized comparative study aimed to assess the efficacy of transplanting autologous melanocyte-keratinocyte suspension in patients with stable vitiligo and to compare site preparation using dermabrasion vs microneedling. (medscape.com)
  • We investigated the long-term safety and efficacy of autologous fibroblast transplantation for participants with mild to severe facial contour deformities. (celljournal.org)
  • This study aims to examine the efficacy and safety of ABM-MSC and ABM-MNC transplantation in T2DM and explores alterations in glucose-insulin homeostasis by metabolic studies. (drcalapai.com)
Peripheral blood2
  • The successful protocol involved arthroscopic microdrilling/ microfracture surgery followed by postoperative injections of autologous peripheral blood progenitor cells (PBPCs) and hyaluronic acid. (wikipedia.org)
  • Five patients received autologous HSCT: threemarrow and two peripheral blood stem cells. (cancernetwork.com)
Lymphoma5
  • Autologous bone marrow transplantation as compared with salvage chemotherapy in relapses of chemotherapy-sensitive non-Hodgkin's lymphoma. (smw.ch)
  • High-dose therapy and autologous bone marrow transplantation after failure of conventional chemotherapy in adults with intermediate-grade or high-grade non-Hodgkin's lymphoma. (smw.ch)
  • The role of intensive therapy and autologous blood and marrow transplantation for chemotherapy-sensitive relapsed and primary refractory non-Hodgkin's lymphoma: identification of major prognostic groups. (smw.ch)
  • CONCLUSION: These data demonstrate the feasibility of allogeneic orautologous HSCT in heavily pretreated lymphoma patients who also receivedtositumomab/iodine-131 tositumomab. (cancernetwork.com)
  • Methods: A PubMed, EMBASE, and Cochrane search yielded 4 comparative studies reporting allogeneic versus HDT with autologous SCT outcomes in adults (age ≥18) with transformed low-grade lymphoid malignancies, including follicular, chronic/small lymphocytic, and marginal zone lymphoma. (arizona.edu)
Outcome2
  • Implantation of autologous bone marrow stem cells in avascular necrosis of femoral head is a safe and effective procedure and has better outcome than bone marrow for early stage of avascular necrosis of femoral head. (nih.gov)
  • Not only do these new innovations have the potential to improve the possibility of transplantation for more patients, they also have potential to improve the outcome of transplantation or dialysis-related renal cancer diagnosis. (krcp-ksn.org)
Progenitor cells1
  • We investigated whether catheter-based, intramyocardial transplantation of autologous endothelial progenitor cells can enhance neovascularization in myocardial ischemia. (stemyoon.org)
Transplant3
  • Allogeneic vs. Autologous Stem Cell Transplant: Which is Right for You? (stemcellmia.com)
  • In an autologous transplant, your stem cells are collected and reintroduced to your body after an outpatient medical treatment. (stemcellmia.com)
  • Aim: To report our experience with ALOHT in acute myelogenous leukemia (AML), analyzing patient age at transplantation in different periods and transplant results in different age groups. (scielo.org)
Marrow transplantation6
  • To the best of our knowledge, this is the first report in which autogenous bone marrow transplantation, noninvasive to the iliac crest, was performed in an incomplete AFF patient. (hindawi.com)
  • The place of high-dose BEAM therapy and autologous bone marrow transplantation in poor-risk Hodgkin's disease. (smw.ch)
  • Dose intensification with autologous bone-marrow transplantation in relapsed and resistant Hodgkin's disease: results of a BNLI randomised trial. (smw.ch)
  • Severe adverse impact on sexual functioning and fertility of bone marrow transplantation, either allogeneic or autologous, compared with consolidation chemotherapy alone: analysis of the MRC AML 10 trial. (ox.ac.uk)
  • Currently more than 60% of ALOHT reported to the Center for International Bone Marrow Transplantation Research (CIBMTR) are performed in patients older than 40 years. (scielo.org)
  • MM is considered relative paucity of CNS invasion by MM an incurable disease despite various meth- in comparison with other tumours, whether ods of treatment, including autologous bone solid or haematological, remain unknown, marrow transplantation [ 3 ]. (who.int)
Patients25
  • Methods A retrospective case series analysis was performed with 403 patients (420 eyes) who underwent extensive fascial resection combined with autologous limbal stem cell sharing transplantation in the Department of Ophthalmology, Second People's Hospital of Yunnan Province from January 2017 to June 2018. (researchsquare.com)
  • Dermabrasion versus microneedling in transplantation of autologous noncultured melanocyte-keratinocyte cell suspension in patients with vitiligo. (medscape.com)
  • One ACI treatment, called MACI (autologous cultured chondrocytes on a porcine collagen matrix), is indicated for healthy patients 18-55 with medium to large sized damage to their cartilage. (wikipedia.org)
  • Autologous CD34 + cells were transplanted in 15 patients with tibia nonunion and 10 patients with femur nonunion, who were followed up for 52 weeks post transplantation . (bvsalud.org)
  • In recent years, the osteochondral autologous transplantation has been researched and proven to provide more complete surface defect coverage and increased healing times in patients that underwent this option for surgery and should be the preferred method for articular cartilage deformity repair. (wku.edu)
  • After standardization of the technique, fibrin-cultured autologous epithelial sheets were transplanted onto the corneal surface of 5 patients with limbal stem cell deficiency due to chemical burns. (arvojournals.org)
  • After transplantation of autologous fibrin-cultured limbal cells, the patients' corneas showed complete epithelialization and a decrease in corneal scarring and vascularization by 2 weeks following surgery. (arvojournals.org)
  • The authors also reported at the Endocrine Society annual meeting that patients improved their diabetes-related outcomes after initially undergoing off-site islet isolation, during which the pancreas is taken out of the body (procedure done at Massachusetts General Hospital in Boston) before transitioning to on-site autologous islet transplantation. (medpagetoday.com)
  • Islet auto-transplantation either on-site or off-site islet isolation can be used to avert the burden of complicated and costly diabetic care for carefully selected patients requiring total or sub-total pancreatectomy," they wrote. (medpagetoday.com)
  • Six patients relapsed, includingall five autologous and one allogeneic recipients. (cancernetwork.com)
  • CONCLUSIONS: RSA in OBPI patients demonstrated a significant improvement of pain symptoms and a moderate improvement in daily activities, anyway with a more appreciable quality of life over time even if the marked hypotrophy especially of the posterior shoulder muscles showed some limits in maintaining suspension of the upper limb and a minor external rotation, with an internal rotation attitude during the movements. (bvsalud.org)
  • Patients and Methods We performed a multicenter retrospective study of DLBCL patients who underwent auto-HCT (n = 160), who experienced complete remission after transplantation, and who then underwent surveillance imaging. (northwestern.edu)
  • When considering stem cell therapies, a key decision for many patients is the choice between Autologous and Allogeneic Stem Cell Transplants. (stemcellmia.com)
  • Stem cell therapy for various ailments using autologous cells ensures that treatments are specialized to individual patients. (stemcellmia.com)
  • Using the cells obtained from two patients, we analyzed the activation of autologous and allogeneic T-lymphocytes and NK-cells co-cultured with target cells. (biomedcentral.com)
  • CONCLUSION: Patients with sASCT with relapsed MM demonstrated a comparative reduction in QoL and greater impact of treatment adverse effects lasting for 6 months and up to 2 years for pain, after which patients who had received sASCT reported better outcomes. (ucl.ac.uk)
  • Autologous hematopoietic stem cell treatment (AHSCT) is considered an effective treatment option for patients with aggressive relapsing-remitting multiple sclerosis (RRMS). (ku.dk)
  • Conclusion: AHSCT of patients with aggressive RRMS was an effective and relatively safe treatment with few serious AEs and no mortality in Danish patients. (ku.dk)
  • We conducted a pooled analysis of the clinical outcomes of allogeneic versus high-dose therapy (HDT) with autologous SCT in adult patients with transformed low-grade lymphoid malignancies. (arizona.edu)
  • METHODS: A cross-sectional study of sexual health and infertility was conducted in 479 patients with acute myeloid leukemia (AML) in first complete remission (CR) who were entered into the UK MRC AML 10 trial comparing allogeneic BMT (Allo-BMT), autologous BMT (A-BMT), and intensive consolidation chemotherapy (CCT). (ox.ac.uk)
  • Causes of mortality in those patients were severe viral pneumonia, post-transplantation hemophagocytic syndrome and meningeal GVHD refractory to ruxolitinib. (scielo.org)
  • Ten patients with confirmed ALS without transplantation were used as a control group. (cellsurgicalnetwork.com)
  • RESULTS: The autologous transplantation of CD133(+) stem cells into the frontal motor cortex is a safe and well-tolerated procedure in ALS patients. (cellsurgicalnetwork.com)
  • and umbilical cord blood (PUCB), capable of 2017), associated with the results of the procedure restoring spinal cord function and immunology of and require a process of hospitalization and patients with indication for transplantation, with the prolonged hospital recovery. (bvsalud.org)
  • Also, drastic changes in daily living habits, qualified and responsible for the implementation of changes in body image, long duration of treatment, HSCT since 2004, agreed to the Brazilian Unified periods of hospitalization and protective isolation, Health System, which meets the needs of the feeling of loss of control, fear of death and lack of patients with an indication for transplantation. (bvsalud.org)
Survival3
  • Conclusions The cyclophosphamide-thalidomide-dexamethasone regimen showed improved response rates and was not inferior in terms of survival outcomes to the standard infusional regimen of cyclophosphamide-vincristine-doxorubicin-dexamethasone. (haematologica.org)
  • Conclusion We observed good clinic and radiographic results, with survival of 79.54% in a mean follow-up of 9.65 years. (bvsalud.org)
  • Autologous transplantation conferred relapse-free and overall survival benefit over chemotherapy consolidation alone, the current standard in the United States, and it might constitute a valuable option for ethnic/racial minorities. (elsevierpure.com)
Weeks after transplantation4
  • The heart was explanted at 2, 6 and 1 2 weeks after transplantation for histological studies. (jgc301.com)
  • The mature blood vessel index was highest in group-4 at 6 and 1 2 weeks after transplantation. (jgc301.com)
  • In the swine study, ischemic area by NOGA mapping, Rentrop grade angiographic collateral development, and echocardiographic left ventricular ejection fraction improved significantly 4 weeks after transplantation of NA/CD31+ MNCs but not after injection of NA/CD31- MNCs or PBS. (stemyoon.org)
  • Capillary density in ischemic myocardium 4 weeks after transplantation was significantly greater in the NA/CD31+ MNC group than the control groups. (stemyoon.org)
Limbal1
  • Introduction To observe the short-term and long-term effects of extensive fascial resection combined with autologous limbal stem cell sharing transplantation for pterygium. (researchsquare.com)
Tissue3
  • and 5) autologous tissue composite. (ersjournals.com)
  • Currently, an autologous tissue composite, with or without a tracheal allograft, is the only long-term working solution for every aetiology, despite its technical complexity and setbacks. (ersjournals.com)
  • Although both melatonin and oxytetracycline were found to be effective in autologous intraperitoneal pelvic ovary transplantation, melatonin is more effective against both the ovarian necrosis and tissue MDA level in rats. (nel.edu)
Acute myeloid1
Outcomes1
  • These favorable outcomes encourage future clinical trials of catheter-based, intramyocardial transplantation of autologous CD34+ MNCs in the setting of chronic myocardial ischemia. (stemyoon.org)
Injections1
  • In this open-label, single-arm phase IIa clinical trial, a total of 57 participants with wrinkles (n=37, 132 treatment sites) or acne scars (n=20, 36 treatment sites) who had an evaluator's assessment score of at least 2 out 7 (based on a standard photo-guide scoring) received 3 injections of autologous cultured fibroblasts administered at 4-6 week intervals. (celljournal.org)
Stem cell4
  • A common example would be using autologous stem cells for knee stem cell treatment, or even stem cell hair treatment to address hair loss after covid - an unfortunate side effect some experience, commonly referred to as covid hair loss. (stemcellmia.com)
  • Our cutting-edge stem cell technologies harness the power of autologous stem cells for a range of treatments. (stemcellmia.com)
  • At Miami Stem Cell, we're proud to offer autologous stem cell therapy to Miami residents and from around the world trust, administered by some of the best stem cell medical doctors in Florida. (stemcellmia.com)
  • If you're pondering where to get stem cell therapy and are keen on tapping into the potential of your body's healing capabilities, autologous stem cell treatments at Miami Stem Cell offer a promising solution. (stemcellmia.com)
Transplants1
  • So, when considering Allogeneic vs. Autologous transplants, remember that your individual health needs and the expertise of your chosen clinic play pivotal roles. (stemcellmia.com)
Centers2
  • The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
  • Background: In our country, transplantation centers differ in the age limit for allogeneic hematopoietic transplantation (ALOHT). (scielo.org)
Postoperative1
  • And only 1 case had partial depression in the unilateral eyelid and received autologous granular fat transplantation with satisfactory postoperative results. (springer.com)
Underwent2
  • The present report describes an incomplete atypical femoral fracture (AFF) patient who underwent simultaneous autogenous bone transplantation to the resected fracture region during intramedullary nail fixation. (hindawi.com)
  • To report a clinical case study conducted in the Integrated Clinics of the Catholic University of Brasilia in a young melanoderm male patient, 13 years-old, who underwent late tooth transplantation technique, i.e., in two steps: the right upper third molar was transplanted to the socket of the right lower first molar. (bvsalud.org)
Cells9
  • Induced pluripotent stem cells (iPSCs) generated from patient fibroblasts could potentially be used as a source of autologous cells for transplantation in retinal disease. (nature.com)
  • Using a patient's own cells for transplantation would avoid these pitfalls and is possible with induced pluripotent stem cells (iPSCs). (nature.com)
  • Through established protocols 2 , fibroblasts from a skin biopsy can be returned to a pluripotent state and serve as a renewable, autologous source of replacement cells that avoids the ethical complications of hESCs. (nature.com)
  • However, some reports have claimed recently that aberrant gene expression followed by proteome alterations and neoantigen formation can result in iPSCs recognition by autologous T-cells. (biomedcentral.com)
  • This study focused on the comparison of autologous and allogeneic immune response to iPSC-derived cells and isogeneic parental somatic cells used for reprogramming. (biomedcentral.com)
  • Here we report that cells differentiated from iPSCs can be recognized by NK-cells rather than by autologous T-cells. (biomedcentral.com)
  • In summary, we showed that iPSC-derived cells can be sensitive to the cytotoxic potential of autologous NK-cells regardless of HLA-I status. (biomedcentral.com)
  • Myoblasts cultured from satellite cells of adult muscle biopsies survive, develop, and function to revitalize degenerative muscles upon transplantation. (jgc301.com)
  • Both innovations are fully implantable, autologous, personalized with patient cells, and can replace all aspects of kidney function. (krcp-ksn.org)
Treatment4
  • Maci" or autologous cultured chondrocytes on porcine collagen membrane, is a treatment to correct cartilage defects in the knee. (wikipedia.org)
  • Autologous matrix-induced chondrogenesis, which is also known as AMIC, is a biological treatment option for articular cartilage damage bone marrow stimulating technique in combination with a collagen membrane. (wikipedia.org)
  • The conclusions are that it is an effective treatment for full thickness chondral defects. (wikipedia.org)
  • CONCLUSIONS: These results indicate a need to consider quality of life parameters when reviewing treatment options and to instigate effective proactive management strategies for dealing with sexual health problems in leukemia survivors. (ox.ac.uk)
IPSCs1
  • We tested whether CRISPR could precisely edit the pathogenic mutation and produce gene-corrected iPSCs for eventual use in autologous transplantation. (nature.com)
Autogenous1
  • The autogenous transplantation or dental autotransplantation is defined as the replacement of an absent or impaired tooth by another transplanted one, usually the third molar. (bvsalud.org)
Implantation1
  • A review evaluating autologous chondrocyte implantation was published in 2010. (wikipedia.org)
Relapse2
  • Conclusion: HDT followed by autologous SCT was associated with lower TRM and a better OS, but there was no difference in relapse versus allogeneic SCT. (arizona.edu)
  • Autologous SCT may be the better therapeutic option, considering the second chance of allogeneic SCT in the case of relapse. (arizona.edu)
Results2
  • These results have shown that autologous fibroblast transplantation could be a promising remodeling modality with long-term corrective ability and minimal adverse events (Registration Number: NCT01115634). (celljournal.org)
  • Conclusions: Our results are comparable to those reported in developed countries. (scielo.org)
Injection1
  • Autologous transplantation of 10(7) NA/CD31+ MNCs, 10(7) NA/CD31- MNCs, or PBS was performed with a NOGA mapping injection catheter to target ischemic myocardium. (stemyoon.org)
Therapies1
  • This important proof-of-concept finding supports the development of personalized iPSC-based transplantation therapies for retinal disease. (nature.com)
Versus1
  • 0.00001) for allogeneic versus autologous SCT. (arizona.edu)
Mortality1
  • Although mortality rates approach that of the general population after 10 years in certain subgroups, long-term survivors of autologous HCT continue to face challenges affecting their health and well-being. (qxmd.com)
Findings1
  • Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. (cdc.gov)
Membrane1
  • The objective is to access feasibility and safety of a new membrane-assisted autologous chondrocyte product. (ijclinicaltrials.com)
Cartilage1
  • CONCLUSION While there is about a 36-38% prevalence of articular cartilage injuries in collegiate athletic settings, there are an abundance of techniques that have been used to treat them. (wku.edu)