• This study uses a cohort sample of 12,644 to 13,832 mother-child pairs from the UK Born in Bradford Study to examine the associations between maternal metabolic syndrome classification (MetS) and child development outcomes at age 5, using cord blood markers as candidate mediators. (biomedcentral.com)
  • Metabolic syndrome (MetS) and obesity are serious health problems in the World, including Turkey. (balkanmedicaljournal.org)
  • The central obese group had significantly higher insulin levels, components of MetS, the ratio free triiodothyronine (fT3) to free thyroxin fT4, and fT4 than those of peripheral obese and control groups. (balkanmedicaljournal.org)
  • Metabolic syndrome (MetS) is a group of cardiovascular risk factors characterized by the presence of low-grade chronic inflammation. (edu.pe)
  • MetS was considered according to the Harmonizing the Metabolic Syndrome criteria. (edu.pe)
  • Metabolic syndrome (MetS) is associated with several degenerative diseases, including retinal degeneration. (molvis.org)
  • The alarming increase in the prevalence of obesity or MetS is likely to further exacerbate the risk for ophthalmic abnormalities associated with obesity. (molvis.org)
  • There are limited data on the prevalence rate of Metabolic Syndrome (MetS) among college students attending any Historically Black College and University (HBCU), which are mostly attended by young African Americans (AA). (biomedcentral.com)
  • Background: Warning signs of metabolic syndrome (MetS) can appear during childhood. (itmedicalteam.pl)
  • Conclusions: The prevalence of MetS among overweight and obese Palestinian schoolchildren is high with dyslipidemia being the most common MetS abnormality. (itmedicalteam.pl)
  • Metabolic Syndrome (MetS) and Type 2 diabetes (T2D) are clinical conditions involving the impaired uptake and utilization of glucose, altered lipid metabolism, and the disruption of the metabolic signaling pathways that regulate insulin secretion from pancreas ( 1 ). (frontiersin.org)
  • Background People with HIV are at for metabolic syndrome (MetS) and fatty liver disease, but the role of Antiretroviral therapy (ART) is poorly understood. (elsevierpure.com)
  • To assess whether a diagnosis of the metabolic syndrome (MetS) improves the prediction of cardiovascular disease or total mortality beyond that already provided by conventional risk factors. (mja.com.au)
  • The use of MetS variables on an ordinal scale produced broadly similar conclusions. (mja.com.au)
  • To determine the prevalence of the metabolic syndrome (MetS) and its related risk factors in a group of healthy subjects. (org.sa)
  • M etabolic syndrome (MetS) prevalence has been rising steadily over the past few decades all over the world. (org.sa)
  • The World Health Organization (WHO) made the first attempt in 1998, defining MetS as a syndrome categorized by insulin resistance and the presence of insulin resistance was an essential component of the syndrome, with a minimum 2 from following criteria: raised triglycerides, low high density lipoprotein (HDL-C) levels, raised blood pressure, obesity, and microalbuminuria. (org.sa)
  • While in 2005 the International Diabetes Federation (IDF) added central obesity as a requirement for MetS diagnosis, focusing on waist circumference as a simple screening tool. (org.sa)
  • Non-alcoholic fatty liver disease (NAFLD) is mutually and bidirectionally linked with metabolic syndrome (MetS) of which it is both the cause and the consequences. (biomedcentral.com)
  • Explain the relationship between metabolic syndrome (MetS) and periodontal disease, and a potential assessment tool for MetS risk. (dimensionsofdentalhygiene.com)
  • According to the 2005 IDF criteria, subsequently revised in 2009, abdominal obesity is identified as the waist circumference of ≥80 cm in women and ≥94 cm in men. (hindawi.com)
  • Abdominal obesity is the major disorder constituting a base for the development of metabolic syndrome. (hindawi.com)
  • Evidence from the conducted studies has revealed that abdominal obesity (assessed based on the waist circumference) plays a very important role in the development of metabolic disorders and in the assessment of cardiovascular risk. (hindawi.com)
  • Due to the limitations of BMI methodology, current reports by the World Health Organization and other organizations suggest combining the measurements of BMI and abdominal obesity [ 11 ]. (hindawi.com)
  • This has led to an increasing evidence for abdominal obesity indices such as waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) as predictors of CVD [ 16 , 17 ]. (hindawi.com)
  • Among the five components, TT was most strongly associated with hypertriglyceridemia and abdominal obesity . (symptoma.com)
  • High blood pressure (24.1%), abdominal obesity (20.7%) and low HDL-c (19.0%) were the most prevalent components of MS among men, while abdominal obesity (26.2%), low HDL-c (19.3%) and hypertriglyceridemia (12.0%) were more prevalent in women. (symptoma.com)
  • Metabolic syndrome was defined with the ATP-III criteria with modification for male abdominal obesity . (symptoma.com)
  • Diabetic Metabolism Research Reviews 15, 427 - 441 Bjorntorp, P ( 2000 ) Do stress reactions cause abdominal obesity and comorbidities. (symptoma.com)
  • It's actually the term for a cluster of conditions, including abdominal obesity , high triglyceride levels, high fasting blood sugar levels, high blood pressure or low HDL cholesterol. (symptoma.com)
  • Clinical and investigational evidence suggests that the increased breast cancer risk associated with greater abdominal visceral obesity may be related to anomalous insulin signaling through the insulin receptor substrate 1 pathway, leading to insulin resistance, hyperinsulinemia, and increased concentrations of endogenous estrogen and androgen. (ijmpo.org)
  • We investigated pathogenic DYRK1B variants causative of abdominal obesity-metabolic syndrome 3 (AOMS3) in a group of patients originally diagnosed with type 2 diabetes. (biomedcentral.com)
  • Central obesity refers to excessive abdominal fat around the stomach area, which increases your chances significantly towards developing this disease. (getoberit.com)
  • but there was no significant difference between central and peripheral obese groups. (balkanmedicaljournal.org)
  • 38 In a multicentered, randomized controlled trial that studied the effects of periodontal treatment on secondary prevention of cardiovascular disease, Offenbacher et al 39 demonstrated that obesity may exert such a dominant influence that when obese individuals undergo periodontal therapy, its presence may nullify the effects of periodontal treatment on high-sensitivity C-reactive protein (hs-CRP), a sensitive marker of systemic inflammation. (dimensionsofdentalhygiene.com)
  • Epidemiological studies suggest that the prevalence and severity of obesity have increased to epidemic proportions worldwide, making it a global public health problem. (molvis.org)
  • Obesity and metabolic syndrome (O&MS) due to the worldwide obesity epidemic affects children at all stages of chronic kidney disease (CKD) including dialysis and after kidney transplantation. (springer.com)
  • A greater understanding of the contribution of gut microbiota towards host pathophysiology is revealing new therapeutic avenues to tackle the global obesity epidemic. (biomedcentral.com)
  • Factors contributing towards the obesity epidemic include an increased accessibility to energy-dense foods, an increase in sedentary activity and the possible involvement of the gut microbiota on host metabolism. (biomedcentral.com)
  • The relevance of the study is also to show that the epidemic of overweight (overweight + obesity) has affected all Brazilian regions and schools, regardless of social background. (bvsalud.org)
  • CONCLUSIONS-TNF-α neutralization ameliorates vascular reactivity in metabolic syndrome during hyperinsulinemia likely in relation to decreased oxidative stress thereby suggesting an involvement of inflammatory cytokines in vascular dysfunction of these patients. (cancerrealitycheck.com)
  • This study therefore assessed the effects of TNF-α neutralization by the monoclonal antibody infliximab on vascular reactivity during hyperinsulinemia in metabolic syndrome. (cancerrealitycheck.com)
  • In Study 2 to assess whether the effect of infliximab on vascular response to ACh might relate to reduction of oxidative stress six additional patients with metabolic syndrome underwent a Mycophenolic acid Mycophenolic acid first dose-response curve to ACh during hyperinsulinemia alone. (cancerrealitycheck.com)
  • Hyperinsulinemia: the key feature of a cardiovascular and metabolic syndrome. (mja.com.au)
  • Against this, physicians should pay attention to glucose, lipid profile, and central obesity in patients with elevated plasma CRP levels. (edu.pe)
  • Aniamls fed GW-501516 along with a calorie-dense diet showed reducded obesity and improved insulin resistance, effects that were accompanied by enhanced metabolic rate and fatty acid β-oxidation, proliferation of mitochondria (the powerhouses of cells), and a significant reduction of lipid fat droplets in skeletal muscles. (umbrellalabs.is)
  • This syndrome involves a collection of cardiovascular risk factors like elevated blood pressure , increased blood sugar, abnormal lipid levels, and central obesity. (tellygupshup.org)
  • Clustering of metabolic abnormalities had significantly increased by increasing body mass index and waist circumferences, and with decreased HDL and elevated triglyceride. (itmedicalteam.pl)
  • Central nervous system abnormalities, including small head size, intellectual disability , poor fine motor skills, or poor eye-hand coordination. (symptoma.com)
  • Conclusion: This study gave a prevalence rate of 8.4% (IDF definition) in the Littoral Region of Cameroon. (journalcra.com)
  • Reports from Lagos, Nigeria, for instance, showed the prevalence rate of metabolic syndrome as high as over 80% among diabetic patients. (wikipedia.org)
  • Conclusions: Although so-called pattern recognition techniques bear high promise in improving clinical decision making, the results should be presented with caution and preferably in comparison with a less complicated technique. (psychiatrist.com)
  • Regarding the important impact on clinical outcomes of metabolic syndrome in patients with chronic kidney disease, clarification of the relationship between metabolic syndrome and adiponectin level is mandatory. (biomedcentral.com)
  • Across the Northwest, Mediterranean, Atlantic European Mainland and Central Europe zones, demographic, lifestyle, clinical and laboratory data were collected from eligible patients during one clinic visit. (wikipedia.org)
  • Clinical value of the metabolic syndrome for long term prediction of total and cardiovascular mortality: prospective, population based cohort study. (mja.com.au)
  • A cohort of children and adolescents with overweight or obesity underwent clinical and metabolic assessment and fundus oculi examination, in order to identify clinical and hormonal risk factors for early retinopathy. (biomedcentral.com)
  • Obesity treatment recommendations in the Philippines: Perspective on their utility and implementation in clinical practice. (asean-endocrinejournal.org)
  • BACKGROUND: Cardiopulmonary exercise testing has demonstrated clinical utility in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). (cdc.gov)
  • To formulate clinical practice guidelines for the assessment, treatment, and prevention of pediatric obesity. (medscape.com)
  • In individuals with metabolic symptoms participating in Research 1 infliximab improved the vasodilator response to both ACh (Fig. 1values make reference to the assessment between. (cancerrealitycheck.com)
  • Assessment of metabolic syndrome was done by International Diabetic Federation (IDF) and National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria. (biomedcentral.com)
  • There is a strong rationale for implementing a risk assessment model that considers patients' cumulative inflammatory burden, which may be amplified by obesity and chronic infection from periodontal disease. (dimensionsofdentalhygiene.com)
  • Obesity in Asia: Prevalence and issues in assessment methodologies. (asean-endocrinejournal.org)
  • The application of WHtR provides an alternative anthropometric index of central obesity that avoids the limitations of WC because the inclusion of height into the index enhances the avoidance of any potential confounding of cardiometabolic risk by height [ 19 ]. (hindawi.com)
  • People with the cardiometabolic syndrome have twice the likelihood of developing and dying from cardiovascular disease, and more than seven times the risk of developing diabetes, compared to those with no cardiometabolic risk factors. (wikipedia.org)
  • and obesity 11 all have the potential to add to the inflammatory burden, ultimately promoting cardiometabolic risk. (dimensionsofdentalhygiene.com)
  • In patients with chronic kidney disease, metabolic syndrome has been demonstrated to be the culprit behind diverse complications. (biomedcentral.com)
  • Childhood obesity is a significant health problem and associated with several metabolic and cardiovascular complications [ 6 - 8 ]. (itmedicalteam.pl)
  • Obesity and its complications constitute a substantial burden. (biomedcentral.com)
  • This dual condition leads to metabolic irregularities, the risk of diabetes, and cardiovascular complications. (tellygupshup.org)
  • screening for comorbidities of obesity should be applied in a hierarchal, logical manner for early identification before more serious complications result. (medscape.com)
  • Do Advanced Statistical Techniques Really Help in the Diagnosis of the Metabolic Syndrome in Patients Treated With Second-Generation Antipsychotics? (psychiatrist.com)
  • Fifty women aged between 40 and 80 years with breast cancer and fifty controls of similar age were assessed for metabolic syndrome prevalence and breast cancer risk factors, including age at menarche, reproductive status, live births, breastfeeding, and family history of breast cancer, age at diagnosis of breast cancer, body mass index, and metabolic syndrome parameters. (ijmpo.org)
  • Does a diagnosis of the metabolic syndrome provide additional prediction of cardiovascular disease and total mortality in the elderly? (mja.com.au)
  • The measurements of body mass and body height were performed as a basis, using the ZBMI/age recommended by the WHO for the diagnosis of overweight and obesity as an evaluation parameter. (bvsalud.org)
  • Green tea supplementation increases glutathione and plasma antioxidant capacity in adults with the metabolic syndrome. (worldhealth.net)
  • The worldwide prevalence of obesity has approximately tripled since 1975 with a current estimate of 1.9 billion adults being classed as overweight (body mass index, BMI ≥ 25 kg/m 2 ). (biomedcentral.com)
  • ADULTS WITH DOWN SYNDROME At Park Ridge we specialize in caring for adults with Down syndrome and other intellectual disabilities who require professional nursing and/or rehabilitative medical care. (symptoma.com)
  • Type 2 diabetes (T2D) is a major health concern in the United States with an estimated 18.3 million adults having physician-diagnosed diabetes, an additional 7.1 million adults having undiagnosed diabetes and about 81.5 million having prediabetes, also referred to as metabolic syndrome [ 1 ]. (biomedcentral.com)
  • In 2000, approximately 32% of U.S. adults had the metabolic syndrome. (wikipedia.org)
  • Similar to other Asian countries, cut-off levels for overweight, obesity, and central obesity associated with CMDs are lower than the currently recommended cut-offs among Filipino adults in rural communities, particularly for WC in both sexes. (asean-endocrinejournal.org)
  • In the early 1900s, Élie Metchnikoff, a Russian-born zoologist and microbiologist first postulated the theory that gut microbiota behave as central modulators influencing host homeostasis and metabolism [ 6 ]. (biomedcentral.com)
  • Alterations in diversity and microbiota community structure may affect host metabolism resulting in obesity. (biomedcentral.com)
  • Studies published in the Indian Journal of Endocrinology and Metabolism focused on the prevalence of metabolic syndrome and its components in different African populations using various criteria. (wikipedia.org)
  • With scientific evidence suggesting their role in inflammation, insulin sensitivity, and fat and energy metabolism, inhibition of endocannabinoids may be a tool in reducing the prevalence of metabolic syndrome and augmenting the benefits of physical exercise. (medscape.com)
  • Because skeletal muscle is the major site of insulin-mediated glucose utilization (up to 80% in the postprandial state), losses in skeletal muscle mass may lead to metabolic impairments [ 12 ]. (biomedcentral.com)
  • The conclusion is that prescription of stevia in the doses of 250 and 500 mg/kg/d decreases the omentin level indirectly via activating insulin sensitivity and lowering blood glucose in STZ-induced diabetic rats. (researchgate.net)
  • The results support the hypothesis that maternal metabolic syndrome classification during pregnancy is associated with some child developmental outcomes at age 5. (biomedcentral.com)
  • The study authors submit that: "These results support the hypothesis that green tea may provide antioxidant protection in the metabolic syndrome. (worldhealth.net)
  • The coefficient of effectiveness in reducing anxiety was 83%, depression was 42.3%, and aggression was 82.7%.Conclusion: The results of the present study support the hypothesis that a yoga-based mindfulness training package is effective in reducing the symptoms of emotional behavioral disorders in children. (ac.ir)
  • however, this may vary significantly by age, dietary habits, gender, and even among participants with morbid obesity [ 9 ]. (hindawi.com)
  • OBJECTIVE-Obesity is connected with chronic swelling because of overproduction of proinflammatory cytokines including tumor necrosis element (TNF)-α. (cancerrealitycheck.com)
  • 4 ] The metabolic syndrome could impact the risk of breast cancer through alterations in a number of interrelated hormonal pathways, including those involving insulin, estrogen, cytokines, and growth factors. (ijmpo.org)
  • In people with obesity, fatty tissue releases cytokines that promote inflammation, intensifying insulin resistance and adding to the overall inflammatory state observed in PCOS . (tellygupshup.org)
  • Retinal vascular changes may become evident as an early complication of overweight and obesity, even during childhood and adolescence. (biomedcentral.com)
  • Pediatric obesity has its basis in genetic susceptibilities influenced by a permissive environment starting in utero and extending through childhood and adolescence. (medscape.com)
  • 25% body fat in men) may foretell the presence of metabolic disorders, or downstream precipitation of incident diabetes, cardiovascular disease, and other inflammatory-driven conditions. (dimensionsofdentalhygiene.com)
  • However no clear link has been established between the vascular pathology of metabolic syndrome and a particular Mycophenolic acid inflammatory cytokine in humans. (cancerrealitycheck.com)
  • Current understanding of the metabolic syndrome reveals the presence of an inflammatory component. (encyclopedia.pub)
  • Interestingly, metabolic inflammatory processes are evident in the cardiovascular, neuronal, and neurovascular systems, indicating their possible involvement in the etiology of cardiac autonomic dysfunction in the metabolic syndrome [33-35]. (encyclopedia.pub)
  • 12 If periodontitis is left untreated, ongoing low-grade bacteremia is produced-and, like obesity, it adds to the cumulative inflammatory burden. (dimensionsofdentalhygiene.com)
  • In conclusion, the connection between PCOS and obesity involves hormonal imbalances, insulin resistance, and inflammatory pathways. (tellygupshup.org)
  • All of the above-mentioned disorders contribute to metabolic syndrome and are related to the development of type 2 diabetes and ischaemic heart disease. (hindawi.com)
  • It is not currently known whether it may be causally linked to metabolic syndrome (MS), a risk condition for ischaemic cardiovascular disorders. (bmj.com)
  • Children with overweight/obesity secondary to genetic syndromes or hormonal disorders were excluded. (biomedcentral.com)
  • We used logistic regression and optimized artificial neural networks and support vector machines to detect the metabolic syndrome in a cohort of schizophrenic patients of the University Psychiatric Center Kortenberg, KU Leuven, Belgium. (psychiatrist.com)
  • The median adiponectin level was 10.7 μg/mL and 585 (44.3%) patients had metabolic syndrome. (biomedcentral.com)
  • The study group consisted of 839 patients with diagnosed metabolic syndrome: 345 men (41.1%) and 494 women (58.9%) aged 32-80. (hindawi.com)
  • The number of patients with metabolic syndrome increases with age. (hindawi.com)
  • The antioxidant vitamin C improved the vasodilator response to ACh in patients with metabolic syndrome but its effect was not further enhanced by concurrent administration of infliximab. (cancerrealitycheck.com)
  • RESEARCH DESIGN AND METHODS- A total of 16 patients with metabolic syndrome (National Cholesterol Education Program Adult Treatment Panel [NCEP ATP] III criteria) and 13 healthy control subjects approximately matched for sex and age were recruited for this study. (cancerrealitycheck.com)
  • Mycophenolic acid Thereafter while keeping insulin infusion constant patients with metabolic syndrome received infusion of infliximab (200 μg/min for 45 min) and dose-response Mycophenolic acid curves to ACh and SNP were repeated. (cancerrealitycheck.com)
  • The study was meant to estimate the prevalence of metabolic syndrome in patients with breast cancer and to establish its role as an independent risk factor on occurrence of breast cancer. (ijmpo.org)
  • Metabolic syndrome prevalence was found in 40.0% of breast cancer patients, and 18.0% of those in control group ( P = 0.02). (ijmpo.org)
  • Metabolic syndrome is more prevalent in breast cancer patients and is an independent risk factor for breast cancer. (ijmpo.org)
  • The high prevalence of CAN in patients newly diagnosed with T2D suggests that its pathophysiology is rooted in an earlier stage of metabolic derangement, possibly being prediabetes. (encyclopedia.pub)
  • Patients first should be treated for the metabolic condition that is causing or exacerbating their hyperlipidemia. (medscape.com)
  • This review focuses on causal relationships and associations with obesity, proposed central mechanisms encouraging the development of obesity and promising prospective methods for microbiota manipulation. (biomedcentral.com)
  • Obesity is a chronic disease with a multifactorial etiology, brought about by a set of genetic, environmental and psychological factors. (bvsalud.org)
  • However, none of the advanced statistical methods could improve on the results obtained using a very simple and naive model including only central obesity and information on blood pressure. (psychiatrist.com)
  • Methods Cryopreserved plasma was obtained from a completed, prospective trial of HIV-infected women with central adiposity on NNRTI- or PI-based ART during which they were randomized to remain on their current ART or switch to a RAL based regimen. (elsevierpure.com)
  • Although some behavioral and pharmacotherapy studies report modest success, additional research into accessible and effective methods for preventing and treating pediatric obesity is needed. (medscape.com)
  • Furthermore, continued investigation into the most effective methods of preventing and treating obesity and into methods for changing environmental and economic factors that will lead to worldwide cultural changes in diet and activity should be priorities. (medscape.com)
  • In this CPR, we discuss the management of obesity and metabolic syndrome (O&MS) in children and adolescents with CKD stages 2-5 and on dialysis, as well as after kidney transplantation, focusing on non-pharmacological treatment (diet, physical activity and behavior modification). (springer.com)
  • The screening for retinopathy should be proposed to all children and adolescents with overweight/obesity. (biomedcentral.com)
  • In the last three decades, overweight and obesity have become a relevant health issue for a significant proportion of children and adolescents. (biomedcentral.com)
  • A single-centre cross-sectional study was performed on a cohort of consecutive Caucasian Italian children and adolescents with overweight (BMI between + 1.75 and + 2 SDS) or obesity (BMI ≥ + 2 SDS). (biomedcentral.com)
  • Pediatric obesity remains an ongoing serious international health concern affecting ~17% of US children and adolescents, threatening their adult health and longevity. (medscape.com)
  • An increase in relative skeletal muscle mass over time has a potential preventive effect on developing metabolic syndrome, independently of baseline skeletal muscle mass and glycometabolic parameters. (biomedcentral.com)
  • Hence, this study aims to recognize various risk factors including metabolic components and blood parameters to predict the possible incidence of the disease. (biomedcentral.com)
  • In addition, several medications affecting adiponectin level and metabolic derangements such as statins or fibrates were not considered in most previous research studies. (biomedcentral.com)
  • Conclusion In women with HIV and central obesity, the hepatic steatosis/fibrosis marker Chi3L1 and adiponectin decrease in conjunction with sST2 decreases following switch to RAL. (elsevierpure.com)
  • All participants without metabolic syndrome in a 2009 study in Zahedan, available in 2017, were included in this study. (who.int)
  • In Central Europe 44% of the participants had type 2 diabetes compared with 33% in the Atlantic European Mainland, and 26% in the Northwest and the Mediterranean regions. (wikipedia.org)
  • Worldwide, 6.3 to 33% of the general populations are estimated to suffer from the disease with even higher prevalence in the group sharing metabolic co-morbidities. (biomedcentral.com)
  • Hispanics had better health outcomes than whites for most analyzed health factors, despite facing worse socioeconomic barriers, but they had much higher death rates from diabetes, chronic liver disease/cirrhosis, and homicide, and a higher prevalence of obesity. (cdc.gov)
  • Skeletal muscle mass was negatively associated with metabolic syndrome prevalence in previous cross-sectional studies. (biomedcentral.com)
  • The aim of this study was to investigate the impact of baseline skeletal muscle mass and changes in skeletal muscle mass over time on the development of metabolic syndrome in a large population-based 7-year cohort study. (biomedcentral.com)
  • Furthermore, to date, no studies have investigated the relationship between changes in skeletal muscle mass over time and metabolic syndrome development. (biomedcentral.com)
  • Therefore, we investigated whether baseline skeletal muscle mass and its changes over time have independent associations with metabolic syndrome development in a large 7-year longitudinal study. (biomedcentral.com)