Conclusions exposure to fluoroquinolones fluoroquinolones. Medical search. Frequent questions

Lower rates of hospital-acquired CDI may be due to fewer cases caused by the hypervirulent fluoroquinolone-resistant ribotype 027, along with reduced use of fluoroquinolone antibiotics and greater attention to preventive measures. (mlo-online.com)
However, surveillance of consumer exposure to antibiotics through poultry consumption is limited. (wikipedia.org)
It turned out that the four medications all belonged to the same class of antibiotics, called fluoroquinolones. (newkerala.com)
Fluoroquinolones (FQs) were introduced as broad-spectrum antibiotics. (biomedcentral.com)
Indeed, widespread use of broad-spectrum antibiotics such as clindamycin, cephalosporins, penicillin, and fluoroquinolones can affect the composition and function of the gut microbiota of patients with COVID-19, leading to reduced colonization resistance capacity against opportunistic pathogens such as C. difficile , and subsequently develop CDI. (frontiersin.org)
Serious adverse reactions to fluoroquinolone antibiotics (FQs) have been reported in medical journals and to the FDA since the 1980s. (squareonepublishers.com)
In 2001, I published an article, "Peripheral Neuropathy with Fluoroquinolone Antibiotics" in the peer-reviewed journal, Annals of Pharmacotherapy . (squareonepublishers.com)
Fluoroquinolone antibiotics, such as levofloxacin, belong to a group of medications called fluoroquinolones. (arvidweb.com)
Antibiotics such as, Fluoroquinolones, especially Levofloxacin , can give false positive tests for buprenorphine and morphine/opiates. (drugtestkitusa.com)

Levofloxacin (LVX) is a broad-spectrum fluoroquinolone antibiotic. (dovepress.com)
To evaluate the rate of bacteremia and the presence of fluoroquinolone resistance in pediatric patients with AML, with relapsed ALL, or undergoing HSCT who are receiving levofloxacin prophylaxis compared with no prophylaxis. (jhoponline.com)
However, a noticeably higher proportion of the cultures that were positive for viridans streptococci were resistant to fluoroquinolones after exposure to levofloxacin versus the control group (80% vs 0%, respectively). (jhoponline.com)
Fluoroquinolone resistance may rise with the increased use of levofloxacin prophylaxis. (jhoponline.com)
We demonstrated that Escherichia coli cells exposed to levofloxacin (LVFX), a fluoroquinolone (FQ), induce the syntheses of heat shock proteins and RecA. (biomedcentral.com)
A healthy 91-year-old Caucasian man was placed on fluoroquinolone (levofloxacin) therapy for a presumed bacterial pneumonitis. (biomedcentral.com)

These associations include a higher prevalence of methicillin resistance in tetracycline resistant S. aureus, penicillin resistance in S. pneumoniae, macrolide and clindamycin resistance in S. pyogenes, fluoroquinolone resistance in S. enterica subsp. (itg.be)
CONCLUSION: These results suggest that studies evaluating the effects of doxycycline PEP should include the effects of doxycycline on resistance not only to doxycycline but also to other antimicrobials and in a broader array of bacterial species than has been included in doxycycline PEP studies thus far. (itg.be)
Thus, the main global objectives of SATURN were to study the impact of antibiotic exposure on antimicrobial resistance (AMR) and to define strategies to improve knowledge on antibiotic selection pressure and judicious antibiotic use. (europa.eu)
Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus. (unl.pt)
http://www.ncbi.nlm.nih.gov/pubmed/?term=Exploring+the+contribution+of+efflux+on+the+resistance+to+fluoroquinolones+in+clinical+isolates+of+Staphylococcus+aureus. (unl.pt)
In this work we used several methodologies to characterize the efflux activity of 52 S. aureus isolates resistant to ciprofloxacin collected in a hospital in Lisbon, Portugal, in order to understand the role played by these systems in the resistance to fluoroquinolones. (unl.pt)
Augmented efflux activity was detected in 12 out of 52 isolates and correlated with increased resistance to fluoroquinolones. (unl.pt)
Addition of efflux inhibitors did not result in the full reversion of the fluoroquinolone resistance phenotype, yet it implied a significant decrease in the resistance levels, regardless of the type(s) of mutation(s) found in the quinolone-resistance determining region of grlA and gyrA genes, which accounted for the remaining resistance that was not efflux-mediated. (unl.pt)
The results obtained in this work do not exclude the importance of mutations in resistance to fluoroquinolones in S. aureus, yet they underline the contribution of efflux systems for the emergence of high-level resistance. (unl.pt)
All together, the results presented in this study show the potential role played by efflux systems in the development of resistance to fluoroquinolones in clinical isolates of S. aureus. (unl.pt)
Secondary endpoints focused on the correlation between fluoroquinolone-resistance in all urinary E. coli isolates and post-TBP infection and risk factors for infection due to fluoroquinolone-resistant E. coli infection. (paijournal.com)
The increasing incidence of fluoroquinolone-resistant E. coli infections after TBP occurred in parallel with increasing rates of fluoroquinolone-resistance in all urinary E. coli isolates. (paijournal.com)
In addition to limiting the use of fluoroquinolones, measures such as reducing the breakpoints for antimicrobial susceptibility testing, choice of high-dose short-course of once-daily LVX regimen, and tailoring LVX dose in special patient populations help to achieve the validated pharmacokinetic-pharmacodynamic target and combat the increasing LVX resistance. (dovepress.com)
The secondary outcomes included bacterial resistance to fluoroquinolones, the incidence of Clostridiodes difficile infection, and the incidence of clinically documented infection. (jhoponline.com)
Consumers are exposed to antibiotic resistance through consumption of poultry products that have prior exposure to resistant strains. (wikipedia.org)
Efflux activity was established by fluorometric assays and the relative expression of the genes coding for the main efflux pumps (EPs) of each species quantified by RT-PCR.Results: For each strain tested, exposure to EtBr resulted in the development of a multidrug resistance (MDR) phenotype, which included resistance to fluoroquinolones and decreased susceptibility to bio-cides, including cetrimide, benzalkonium chloride and tetraphenylphosphonium bromide. (unl.pt)
The purpose of the study is to discuss the correlation between the resistance rate of gram negative bacteria to fluoroquinolones (FQ) and antibiotic consumption intensity of 145 China tertiary hospitals in 2014. (biomedcentral.com)
Fluoroquinolones resistance rate varied from hospital to hospital. (biomedcentral.com)
Gyr A and Par C genes, are known to cause resistance especially in Alterations in proteins of fluoroquinolones. (indjst.org)
ESBL-producing Enterobacterales from the GCC region show high levels of resistance to ampicillin, aztreonam, third-/fourth-generation cephalosporins, fluoroquinolones, and trimethoprim-sulfamethoxazole. (frontiersin.org)

OBJECTIVES: Antimicrobial stewardship programmes have focused on reducing inappropriate inpatient antimicrobial prescribing, but several small studies have found a large portion of antimicrobial exposure occurs immediately after hospital discharge. (va.gov)
Fluoroquinolones (38.3%) were the most common post-discharge antimicrobial. (va.gov)
Thirty-nine per cent of the total duration of antimicrobial exposure occurred after discharge. (va.gov)
CONCLUSIONS: A large proportion of antimicrobial exposure among hospitalized patients occurred immediately following discharge. (va.gov)
More specifically in 2012, the FDA speculated the most significant public health threat in regard to antimicrobial use in animals is the exposure of antimicrobial-resistant bacteria to humans. (wikipedia.org)
For all of these reasons, fluoroquinolones are an attractive antimicrobial choice of treatment among healthcare providers in most fields of medical practice. (biomedcentral.com)

Fluoroquinolones, carbapenems and clindamycin are usually employed as alternatives to penicillin and are associated with greater risk of Clostridium difficile colitis, 6 which may increase mortality, hospital stays and overall costs. (bmj.com)

The work package focusing on molecular studies generated new evidence about the changes effected by antibiotic therapy on commensal organisms or opportunistic pathogens in the oropharyngeal, nasal and gastro-intestinal flora and study AMR mechanisms and the dissemination of successful clones of fluoroquinolone-resistant, carbapenem-resistant or extended-spectrum beta-lactamase harboring Gram-negative bacteria, MRSA and fluoroquinolone-resistant viridans streptococci. (europa.eu)

Multivariable analysis revealed that diabetes mellitus and recent cephalosporin exposure were the independent risk factors for baseline colonization by ESBL. (biomedcentral.com)
By multivariable logistic regression analysis, independent risk factors for fluoroquinolone-resistant E. coli UTI after TBP included diabetes mellitus, fluoroquinolone exposure, prior hospitalization, and prior cultures with fluoroquinolone-resistant gram-negative bacilli. (paijournal.com)

The susceptibility to fluconazole and voriconazole and the biofilm formation of the yeasts were tested before and after exposure to the antibacterials. (bvsalud.org)

Because fluoroquinolones, including CIPRO XR, have been associated with serious adverse reactions [see WARNINGS AND PRECAUTIONS ] and for some patients uncomplicated UTI (acute cystitis) is self-limiting, reserve CIPRO XR for treatment of uncomplicated UTIs (acute cystitis) in patients who have no alternative treatment options. (globalrph.com)
The study did not reveal any clear adverse reactions due to in utero exposure to ciprofloxacin. (medlibrary.org)
Attention must be paid to potential side-effects when prescribing any medication, and close follow-up with patients is a medical necessity to evaluate for these adverse reactions, especially with fluoroquinolones. (biomedcentral.com)

Recent reports suggest that infections due to fluoroquinolone-resistant Escherichia coli ( E. coli ) are an increasingly common complication of transrectal biopsy of the prostate (TBP) in the United States. (paijournal.com)
We analyzed the proteins induced in Escherichia coli by exposure to FQs, then examined the susceptibilities to these agents of E. coli strains with mutations in the genes encoding these proteins. (biomedcentral.com)
Here, we investigated human pathogens Escherichia coli causing Urinary Tract Infection [UTI] to explore the possible link between the abundance of mutations, and the exposure to fluoroquinolones. (indjst.org)

Fluoroquinolones, including CIPRO XR, may exacerbate muscle weakness in patients with myasthenia gravis. (globalrph.com)
Cipro is an antibacterial, a fluoroquinolone. (survivalblog.com)
Called fluoroquinolones, they are better known under the names Cipro and Levaquin (as well as four others). (squareonepublishers.com)

Conclusions Obtaining a structured history from the patient and family physician alone can enable an accurate identification of penicillin allergy status. (bmj.com)

BACKGROUND: A number of randomized controlled trials have found that doxycycline post exposure prophylaxis (PEP) can reduce the incidence of gonorrhoea, chlamydia and syphilis in men who have sex with men (MSM). (itg.be)
Our objective is to determine whether the incidence of infections due to fluoroquinolone-resistant E. coli after TBP has increased nationwide in the Veterans Affairs Health Care System and to identify risk factors for infection. (paijournal.com)
The primary outcomes were the incidence of urinary tract infection (UTI) and bacteremia with E. coli and with fluoroquinolone-resistant E. coli strains within 30 days after TBP. (paijournal.com)
In the Veterans Affairs Healthcare System, the incidence of E. coli infection after TBP has increased significantly since 2000 due to a dramatic rise in infections with fluoroquinolone-resistant E. coli . (paijournal.com)
The malformation rates among live-born babies exposed to ciprofloxacin and to fluoroquinolones overall were both within background incidence ranges. (medlibrary.org)
Tendinopathy subsequent to fluoroquinolone treatment, typically classified as tendonitis (inflammatory) or tendinosis (microtears), has an incidence of 2.4 per 10 000 patients. (biomedcentral.com)

Notably, about a third has had no recent antibiotic exposure nor has been admitted to a hospital. (bvsalud.org)
The SATURN project had as aim to study the impact of antibiotic exposure on AMR with a multidisciplinary approach that bridges molecular, epidemiological, clinical and pharmacological research. (europa.eu)
The pharmacodynamic study modelled the relationships between antibiotic exposure and AMR emergence over time for various classes of agents. (europa.eu)

When a gram-negative bacterial infection is suspected in a patient, one of the first-line options for treatment is in the fluoroquinolone family. (wikipedia.org)
It is well known that expression of certain bacterial genes responds rapidly to such stimuli as exposure to toxic chemicals and physical agents. (biomedcentral.com)
Conclusion: These results show that both S. aureus and S. epidermidis have the potential to develop efflux driven MDR phenotypes when exposed to a non-antibiotic substrate of multidrug EPs, which can be mediated by distinct efflux pumps, depending on the drug and the bacterial genetic background. (unl.pt)
It's useful for urinary tract infections, bacterial (not viral) sinusitis, post-inhalation exposure to anthrax, traveler's diarrhea, and in combination with other drugs for abdominal infections. (survivalblog.com)
In conclusion, Ciprofloxacin 500 mg is an effective antibiotic medication for the treatment of various bacterial infections. (topdollsites.com)
In conclusion, Ciprofloxacin 500 mg is a widely used antibiotic that is effective in treating various bacterial infections. (topdollsites.com)
Fluoroquinolones are a powerful and potent tool in the fight against bacterial infection. (biomedcentral.com)

Fluoroquinolones are effective in respiratory, urinary, and gastrointestinal tract infections. (biomedcentral.com)

The independent risk factors for CR-AB and/or CR-PA colonization were cerebrovascular diseases, previous hospitalization, transfer from another hospital/a LTCF and previous nasogastric tube use, whereas those for MRSA colonization were previous fluoroquinolone exposure and previous nasogastric tube use. (biomedcentral.com)

Reduce viral exposures by improved personal hygiene. (medscape.com)

Early treatment and prophylaxis with streptomycin or gentamicin or the tetracycline or fluoroquinolone classes of antimicrobials would be advised. (jamanetwork.com)

A controlled prospective observational study followed 200 women exposed to fluoroquinolones (52.5% exposed to ciprofloxacin and 68% first trimester exposures) during gestation. (medlibrary.org)
There were 70 ciprofloxacin exposures, all within the first trimester. (medlibrary.org)
However, these small postmarketing epidemiology studies, of which most experience is from short term, first trimester exposure, are insufficient to evaluate the risk for less common defects or to permit reliable and definitive conclusions regarding the safety of ciprofloxacin in pregnant women and their developing fetuses. (medlibrary.org)
Ciprofloxacin 500 mg is a prescription medication that belongs to the class of drugs known as fluoroquinolones. (topdollsites.com)
Key findings: Co-administration of ciprofloxacin with riluzole caused significant increase in systemic exposure of riluzole (area under the curve, maximum plasma concentration and mean residence time were found to increase). (researchgate.net)
Conclusions: Co-administration of ciprofloxacin with riluzole increases the systemic levels of riluzole and thereby the oral pharmacokinetic properties of riluzole while co-administration of grapefruit juice with riluzole has no significant effect. (researchgate.net)

Then the correlation between antibiotic usage and fluoroquinolones -resistant (FQR) rate was consequently investigated. (biomedcentral.com)

He also served as a member of teams defending a prescription fluoroquinolone medication in more than 1,500 cases in an MDL litigation and more than 2,000 cases in state courts. (btlaw.com)
Defended prescription fluoroquinolone medication in a federal MDL. (btlaw.com)
In the event of a suspected or confirmed exposure to anthrax, this medication can be taken to reduce the risk of developing the infection. (topdollsites.com)
If an individual tests positive, it's crucial to consider possible explanations, such as legitimate medication use or exposure to substances in the environment. (drugtestkitusa.com)

These results suggest that increased candidemia in ICU patients is not attributable to possible alterations in the yeasts, but is more likely caused by a weakening of the patient's general condition after long exposure to infection. (bvsalud.org)
Conclusion: Even if chest radiographs are important in the workup of patients with COVID-19 infection, the use of baseline radiographs in COVID-19 infection should not be a routine practice. (bvsalud.org)

Being in close proximity to individuals using certain drugs, such as cocaine or methamphetamine, may cause false positive results due to passive exposure. (drugtestkitusa.com)

We also found isolates belonging to the same clonal type that showed different responses towards drug exposure, thus evidencing that highly related clinical isolates may diverge in the efflux-mediated response to noxious agents. (unl.pt)

Bacteria are known to respond to unfavorable conditions, e.g., exposure to toxic chemicals and physical agents, nutrient limitation, or sudden increase in growth temperature, by rapid expression of regulons related to the heat shock, SOS, and oxidative stress responses. (biomedcentral.com)
It belongs to a class of drugs known as fluoroquinolones, which work by inhibiting the growth and spread of bacteria in the body. (topdollsites.com)
In addition, exposure to soaps, disinfectants, medications, and ultraviolet light can modify the types and number of bacteria on the skin. (medscape.com)

The Food and Drug Administration (FDA) has authorized Levofla, which belongs to the fluoroquinolone antibiotic class. (arvidweb.com)

Des infections microbiennes ont été observées chez 30% (155/519) de l'ensemble des malades admis au service de soins intensifs pour adultes de l'Hôpital universitaire de Jordanie à Amman en 1993. (who.int)
A fluoroquinolone, such as Levofla, may be used to treat severe skin infections. (arvidweb.com)

Also, CDI can complicate the outcome of COVID-19 patients, especially in the presence of comorbidities or for those patients with prior exposure to the healthcare setting. (frontiersin.org)
While fluoroquinolone-induced tendon rupture typically accompanies other comorbidities (for example renal impairment) or concurrent steroid therapy, our case represents a medical 'first' in that there were no such comorbidities and no steroid therapy. (biomedcentral.com)

OBJECTIVE: To evaluate the relative contribution of occupational vs. non-occupational secondhand tobacco smoke exposure to overall hair nicotine concentrations in non-smoking bar and restaurant employees. (who.int)

Quantitative comparison of cytocidal effects of tetracyclines and fluoroquinolones on human periodontal ligament fibroblasts. (thejcdp.com)

CONCLUSIONS: Present findings expanded current knowledge about the diversity of emerging KPC enzymes variants with 270-loop alterations that can be encountered in the clinical setting. (imperial.ac.uk)

SATURN aimed to respond to an urgent need, as stated in the EU Council conclusions (June 2008) on AMR, in which the EU "stresses the need of research in the area of AMR, e.g. to increase the understanding of the mechanisms and underlying risk factors that advance the development of AMR and to increase the knowledge of the effectiveness of current and future control measures. (europa.eu)
The work also suggests that exposure to certain drugs and environmental risk factors during embryonic development can cause changes to this gene, leading to alterations in social behavior that are similar to those found in individuals who have autism. (newkerala.com)

This in vitro study assessed smear layer removal and collagen fiber exposure after tetracycline hydrochloride (TTC) application on root surfaces using scanning electron microscopy (SEM). (thejcdp.com)
Another prospective follow-up study reported on 549 pregnancies with fluoroquinolone exposure (93% first trimester exposures). (medlibrary.org)

Although Lesotho has the second highest HIV adult prevalence rate (21.1%) in the world, and the prevalence of orphanhood (44.2%) and violence exposure (67.0%) is high, little research exist on orphanhood vulnerabilities for violence and HIV in Lesotho. (cdc.gov)

Conclusions An aerosolized plague weapon could cause fever, cough, chest pain, and hemoptysis with signs consistent with severe pneumonia 1 to 6 days after exposure. (jamanetwork.com)

it constantly changes form to elude the protective antibodies that the body has developed in response to previous exposures to influenza or to influenza vaccines. (med-chemist.com)

As of February 2014, approximately 45,000 individual cases of fluoroquinolone toxicity have been reported. (squareonepublishers.com)

After treatment with the drug, fish exposed to fluoroquinolones were more likely to swim closer to other fish, demonstrating that the drug helped restore sociability. (newkerala.com)

Smear layer removal and collagen fiber exposure may improve periodontal treatment and regeneration. (thejcdp.com)

It's possible that these four compounds are just the tip of the iceberg in terms of substances that could be problematic for embryonic exposure," Peterson says. (newkerala.com)

The concentrations of 50 mg/mL and 75 mg/mL applied by burnishing were the most effective in smear layer removal and collagen fiber exposure. (thejcdp.com)

fever taken on post-exposure. (grantroaddaycare.com)

Employees used personal air nicotine samplers during working and non-working hours for a 24-h period to assess occupational vs. non-occupational secondhand tobacco smoke exposure and hair nicotine concentrations to assess overall secondhand tobacco smoke exposure. (who.int)

Hair nicotine concentration was not associated with personal air nicotine concentration during non-working hours (non-occupational exposure). (who.int)
CONCLUSIONS: Personal air nicotine concentration at working hours was the major determinant of hair nicotine concentrations in non-smoking employees from Santiago, Chile. (who.int)

Anatomy1

Organisms34

Diseases30

Chemicals and Drugs49

Analytical, Diagnostic and Therapeutic Techniques and Equipment8

Phenomena and Processes12

Information Science1

Health Care3

Antibiotics9

Levofloxacin6

Resistance20

Antimicrobial6

Carbapenems1

Harboring Gram-negative1

Diabetes mellitus2

Susceptibility1

Adverse reactions3

Escherichia3

CIPRO3

Penicillin1

Incidence6

Antibiotic exposure3

Bacterial7

Urinary1

MRSA1

Viral1

Antimicrobials1

Ciprofloxacin6

Correlation1

Medication4

Infection2

Results1

Isolates1

Bacteria3

Belongs1

Infections2

Comorbidities2

Evaluate1

Quantitative1

Findings1

Risk factors2

Study2

Prevalence1

Severe1

Previous1

Cases1

Drug1

Treatment1

Substances1

Effective1

Fever1

Assess1

Concentration2