Concentrations of pyruvate. Medical search. Frequent questions

Samples were analysed for concentrations of glucose, lactate, pyruvate and glycerol. (biomedcentral.com)
Microdialysis results showed that patients with upper gastrointestinal tract lesions had significantly higher levels of postoperative intraperitoneal glucose and glycerol concentrations, as well as lower lactate/pyruvate ratios and lactate/glucose ratios. (biomedcentral.com)
In the group with perforation of the lower gastrointestinal tract, those patients with a complicated course showed lower levels of postoperative intraperitoneal glucose concentration and glycerol concentration and higher lactate/pyruvate ratios and lactate/glucose ratios than those patients with an uncomplicated course. (biomedcentral.com)
We also aimed to evaluate the results from IPM with continuous measurement of lactate, pyruvate, glucose and glycerol concentration in the peritoneal fluid in patients operated for peritonitis due to gastrointestinal tract (GI) perforation. (biomedcentral.com)
Previous research has shown that plasma creatine levels are influenced by extracellular concentrations of insulin and glucose as well as by the intracellular creatine concentration. (springer.com)
The inclusion of the small amounts of pyruvate and citrate were thought unlikely to influence creatine absorption and uptake, although initial studies with 25 g pyruvate plus 75 g dihydroxyacetone have indicated an ergogenic effect of pyruvate supplementation through a proposed stimulation of glucose uptake by muscle [ 6 ]. (springer.com)
Glucose is essential for cell survival and is metabolized to pyruvate ( 13 ). (spandidos-publications.com)
In glycolysis, the 6-carbon glucose is connected to two 3-carbon pyruvate molecules, and then to the 2-carbon acetyl-CoA. (encyclopedia.com)
Rats exposed to airborne concentrations of kerosene averaging 231 mg/m3 showed a decrease in blood glucose titers, as well as increased circulating levels of lactate and pyruvate. (cdc.gov)
The glycolytic pathway converts one hexose (a six-carbon carbohydrate such as glucose) into two triose molecules (three-carbon carbohydrate) such as pyruvate, to produce a net total of two molecules of ATP (four produced, two consumed) and two molecules of nicotinamide adenine dinucleotide (NADH). (jove.com)
After slaughter, tissue samples of the small intestinal mucosa (mid-duodenum and mid-jejunum) were taken for determination of mRNA concentrations of SGLT1 and GLUT2 as well as pyruvate carboxylase, cytosolic phosphoenolpyruvate carboxykinase, and glucose-6-phosphatase by real-time reverse transcription PCR relative to a housekeeping gene. (nih.gov)
Glycolysis breaks glucose (a six-carbon-molecule) down into pyruvate (a three-carbon molecule). (citizendium.org)
Contains 4500 mg\L D-glucose without Sodium Pyruvate. (bioind.com)

Metabolite concentrations, oxygen uptake and 14c-labelled amino acid labelling patterns. (harvard.edu)
To monitor the physiological state of yeast cropped from this fermentation test, we estimated intracellular metabolite concentrations using capillary electrophoresis time-of-flight mass spectrometry (CE-TOFMS). (asbcnet.org)
This study established that the metabolite pyruvate is a good potential biomarker, prognostic of patient outcome at the one-year follow-up after ATR surgery. (nih.gov)

Increased lactate-r was related with less strength limitations in the calf (R = 0.283, P = 0.011), while the elevated lactate-pyruvate ratio, notably, was related to more limitations in walking on uneven surface (R = -0,243, P = 0.027). (nih.gov)
The CO group showed a significantly higher cerebral lactate-to-pyruvate ratio. (lu.se)
Lactic acidosis is characterized by elevated blood lactate levels, acidemia, electrolyte disturbances, an increased anion gap, and an increased lactate/pyruvate ratio. (pdr.net)

Key enzymes involved in thallium toxicity include pyruvate kinase and succinate dehydrogenase. (medscape.com)
Genetic ablation of ketohexokinase or stimulation of pyruvate kinase prevents villus elongation and abolishes the nutrient absorption and tumour growth that are induced by feeding mice with high-fructose corn syrup. (nature.com)
Fig. 2: Fructose metabolism enhances hypoxic cell survival and decreases pyruvate kinase activity. (nature.com)
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses. (nature.com)
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis. (nature.com)
The combined results indicate that glycolysis is regulated by the compartmental expression of hexokinase 2, pyruvate kinase M1, and pyruvate kinase M2 in photoreceptors, whereas the inner retinal neurons exhibit a lower capacity for glycolysis and aerobic glycolysis. (molvis.org)

It is catalyzed by the pyruvate dehydrogenase complex. (wikipedia.org)
Such enzymes include the pyruvate dehydrogenase complex that synthesises the acetyl-CoA needed for the first reaction of the TCA cycle. (citizendium.org)

Cellular concentrations of enzymes and their substrates. (harvard.edu)
Together, these enzymes couple decarboxylation of pyruvate to ethanol with the oxidation of NADH and thus represent an alternative to the AdhE ethanol formation pathway. (researchgate.net)
Also the enzymes citrate synthase, isocitrate dehydrogenase and alpha-ketoglutarate dehydrogenase, that regulate the first three steps of the TCA cycle, are inhibited by high concentrations of ATP. (citizendium.org)
This includes both the entry point enzymes pyruvate dehydrogenase and citrate synthase. (citizendium.org)

Plasma concentrations of glutamine and alanine, the major nitrogen-carrying amino acids, usually are high and that of arginine is low. (nih.gov)
The enzymatic assay targets alanine and employs alanine transaminase (ALT), pyruvate oxidase (POx), and horseradish peroxidase (HRP). (ojp.gov)
It is important to note that alanine has a significantly higher concentration than arginine in the fingerprint content of both males and females. (ojp.gov)

Therefore, any substrate that increases intracellular pyruvate concentration can induce diacetyl accumulation. (ajevonline.org)

Pyruvate enters the tricarboxylic acid cycle to generate energy. (spandidos-publications.com)
Under low-oxygen conditions, pyruvate does not enter the tricarboxylic acid cycle, but is instead metabolized to lactate. (spandidos-publications.com)
Our findings indicate an impaired function of the PDH enzyme complex, resulting in reduced flux of pyruvate to the [tricarboxylic acid ( TCA )] cycle. (medscape.com)

The breakdown of pyruvate irreversibly funnels the products of glycolysis into the Krebs cycle. (encyclopedia.com)
Thus, the transformation of pyruvate to acetyl-CoA is the link between the metabolic reactions of glycolysis and the Krebs cycle. (encyclopedia.com)

Description: Direct determination of Albumin concentrations in biological samples (e More Information: g serum, plasma, urine, etc) Storage. (researchd.com)
Measurements of globulin are calculated (Total protein - Albumin) , and are used to determine the serum globulin concentration. (cdc.gov)
The authors compared serum concentrations of 20 standard amino acids from the 200 patients with ME/CFS and 102 healthy control patients. (medscape.com)
In contrast, the 38 men with ME/CFS had slight but insignificant reductions in serum tyrosine and phenylalanine compared with control patients, but also had significantly elevated concentrations of 3-methylhistidine, a marker of endogenous protein catabolism ( P = .003 compared with healthy men). (medscape.com)

For example, pyruvate formate lyase disproportionates pyruvate into acetyl-CoA and formic acid. (wikipedia.org)
Find N-Acetylneuraminate Pyruvate Lyase (Dihydrodipicolinate Synthase) Proteins with a specific Grade. (antibodies-online.com)
Find N-Acetylneuraminate Pyruvate Lyase (Dihydrodipicolinate Synthase) Proteins for a variety of species such as anti-Human N-Acetylneuraminate Pyruvate Lyase (Dihydrodipicolinate Synthase), anti-Xenopus laevis N-Acetylneuraminate Pyruvate Lyase (Dihydrodipicolinate Synthase), anti-Cow N-Acetylneuraminate Pyruvate Lyase (Dihydrodipicolinate Synthase). (antibodies-online.com)
Find N-Acetylneuraminate Pyruvate Lyase (Dihydrodipicolinate Synthase) Proteins validated for a specific application such as ELISA, WB, SDS, AP. (antibodies-online.com)

Long-COVID patients had different concentrations of lactic acid and arginine, altered lactate-pyruvate and ornithine-citrulline ratios, and significantly higher levels of IL-17. (umn.edu)
When metformin is implicated as the cause of lactic acidosis, metformin plasma concentrations more than 5 mcg/mL are generally found. (pdr.net)

The ratios of the concentration in the injured versus uninjured limb of pyruvate (pyruvate-r) and lactate (lactate-r) were calculated as well as the lactate/pyruvate ratios (L/P-r). (nih.gov)

The aim of this study was to assess essential metabolites pyruvate and its product lactate, as early biomarkers in relation to long-term functional- and patient-reported outcome after ATR. (nih.gov)
The team measured concentrations of 108 metabolites using liquid chromatography and flow injection analysis with tandem mass spectrometry. (umn.edu)

The two hydrogenatoms removed from the pyruvate molecule yield NADH, which subsequently gives up its electrons to the electron transport chain to form ATP and water. (encyclopedia.com)

Each subject was assigned to ingest a single dose of isomolar amounts of creatine (4.4 g) in the form of creatine monohydrate (CrM), tri-creatine citrate (CrC), or creatine pyruvate (CrPyr) using a balanced cross-over design. (springer.com)
The aim of this pilot study was to compare the effects of ingesting isomolar amounts of creatine (4.4 g) in the form of the monohydrate (5 g), tri-creatine citrate (6.7 g) and creatine pyruvate (7.3 g) on creatine concentrations in plasma. (springer.com)

A variety of influences, including dietary protein, arginine and corticosteroids, augment the concentration of NAG in mitochondria. (nih.gov)

Pyruvate undergoes oxidative decarboxylation in which it loses its carboxyl group (as carbon dioxide) to form acetyl-CoA, giving off 33.5 kJ/mol of energy. (wikipedia.org)
The oxidative conversion of pyruvate into acetyl-CoA is referred to as the pyruvate dehydrogenase reaction. (wikipedia.org)
In the patients with ME/CFS, there was a specific reduction of amino acids that fuel oxidative metabolism, pointing to functional impairment of pyruvate dehydrogenase (PDH), a key enzyme for the conversion of carbohydrates to energy. (medscape.com)

The process begins with the oxidation of pyruvate, producing one CO 2 , and one acetyl-CoA. (citizendium.org)

Thallium accumulates in tissues with high potassium concentrations such as muscle, heart, and central and peripheral nerve tissue. (medscape.com)
Furthermore, pyruvate-derived diacetyl accumulates because of a delayed alsD response that prevents acetoin formation. (ajevonline.org)

Cphy0543 is homologous to MgtA, a P-type ATPase upregulated at low ambient Mg 2 ϩ concentrations (35) to mediate Mg 2 ϩ uptake (36) or Ca 2 ϩ /Mg 2 ϩ antiport (37). (researchgate.net)

At two weeks post-injury pyruvate and lactate concentrations were assessed in both the injured and uninjured limbs using microdialysis followed by enzymatic quantification. (nih.gov)

This study examined whether the administration of three different forms of creatine had different effects on plasma creatine concentrations and pharmacokinetics. (springer.com)
Plasma concentration curves, determined over eight hours after ingestion, were subject to pharmacokinetic analysis and primary derived data were analyzed by repeated measures ANOVA. (springer.com)
There was no effect of treatment with CrPyr on the plasma pyruvate concentration. (springer.com)
Characteristically this resulted in higher plasma concentrations of creatine with CrPyr. (springer.com)
At the end of the exposure, both fresh brain (cortical and hippocampal tissue) and heart (apical tissue) were immediately harvested to measure mitochondrial respiration and reactive oxygen species (ROS) generation and blood was collected to assess plasma cytokine concentrations. (lu.se)

In eukaryotes , pyruvate moves into the mitochondria . (citizendium.org)

However, the relationship between the concentration of non-sugar nutrients and yeast metabolism remains unclear. (asbcnet.org)
The purpose of this study was to elucidate the relationship between the concentration of non-sugar nutrients, especially vitamins and minerals, and yeast metabolism and their effects on fermentability and beer quality. (asbcnet.org)
It is assumed that this difference in yeast metabolism is the cause of the insufficient fermentation and increased pyruvate production. (asbcnet.org)
In this context, 1 H MRS has allowed the measurements of energy metabolism-related compounds, whose concentrations can vary under different brain activation states. (frontiersin.org)

While not significant there was a trend to an increase in optically measured cerebral blood flow and hemoglobin concentration in the CO group. (lu.se)

In these experiments, potassium and thiamine concentrations were found to have important roles in yeast fermentation performance. (asbcnet.org)

It is converted to phosphoenol pyruvate (PEP), catalyzed by the enzyme enolase. (sigmaaldrich.com)

After 4 h, both concentrations of PAT significantly depleted reduced glutathione (GSH) levels. (cdc.gov)
Pyruvate dehydrogenase activity levels were inhibited as early as 1 h after cells were treated with both concentrations of PAT. (cdc.gov)

Filter sterilized carcass rinsate for recovery of Salmonella species in various concentrations of cetylpyridinium chloride. (usda.gov)

Description: Direct determination of Histamine concentrations in fish and red wine samples More Information: Storage Conditions: RT for 24. (researchd.com)

Despite the higher peak concentration with CrPyr there was no difference between the estimated velocity constants of absorption (ka) or elimination (kel) between the three treatments. (springer.com)

Mean peak concentrations and area under the curve (AUC) were significantly higher with CrPyr (17 and 14%, respectively) in comparison to CrM and CrC. (springer.com)
Elevated pyruvate-r, at two weeks, was significantly associated with total ATRS (R = 0.254, P = 0.028), less loss in physical activity (R = 0.241, P = 0.039), less experience of pain in FAOS (R = 0.275, P = 0.032), and a higher number of heel-rise repetitions on injured side (R = 0.230, P = 0.040) at 12 months. (nih.gov)
The galactose‑1‑phosphate concentration was significantly higher in cells cultured in HDI than in those cultured with ReproFF. (spandidos-publications.com)
Abundance of SGLT1 mRNA tended to be higher in duodenal than in jejunal mucosa, and mRNA abundances of pyruvate carboxylase tended to be higher in jejunal than in duodenal mucosa. (nih.gov)

Furthermore, when additional pyruvate was added, α-acetolactate synthase ( alsS ) gene expression increased 1.6-fold and the diacetyl concentration increased from 0.4 mg/L to 2.3 mg/L. Although the highest alsS expression (a 10-fold increase) was found 24 hr after pyruvate addition, no further increase in diacetyl concentration was found. (ajevonline.org)

As a result, insufficient fermentation and increased pyruvate production above the threshold limit were observed in the fermentation with a low concentration of some minerals and vitamins. (asbcnet.org)
To augment ethanol production by the ET strain, an alternative ethanol production pathway comprised of pyruvate decarboxylase (Pdc) and alcohol dehydrogenase (AdhB) from Zymomonas mobilis (Fig. 4A) was transferred into C. phytofermentans on the replicating pQexpE plasmid (Fig. 4B). (researchgate.net)

QuantiQuik™ Pyruvate Quick Test Strips is available at Gentaur for next week delivery. (researchd.com)

PAT also significantly inhibited glutathione peroxidase and pyruvate dehydrogenase activity in cardiac myocytes. (cdc.gov)

To make high quality beer, it is important to control the balance of sugar and non-sugar nutrition concentrations. (asbcnet.org)

This study evaluates the effect of exogenous pyruvate on diacetyl formation and the expression of diacetyl-related genes in Oenococcus oeni during winemaking. (ajevonline.org)

This increase in the pyruvate concentration resulted in an unbalanced, acidic flavor. (asbcnet.org)

ORFADIN contains nitisinone, which is a hydroxyphenyl- pyruvate dioxygenase inhibitor indicated as an adjunct to dietary restriction of tyrosine and phenylalanine in the treatment of hereditary tyrosinemia type 1 ( HT -1). (rxlist.com)

Diacetyl formation by Oenococcus oeni was induced by yeast-derived pyruvate in the early stage of winemaking. (ajevonline.org)

N-acetylneuraminate lyases regulate cellular concentrations of N-acetyl-neuraminic acid (sialic acid) by mediating the reversible conversion of sialic acid into N-acetylmannosamine and pyruvate. (antibodies-online.com)

Anatomy14

Organisms17

Diseases9

Chemicals and Drugs162

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Psychiatry and Psychology1

Phenomena and Processes39

Disciplines and Occupations1

Information Science3

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Glucose13

Metabolite3

Ratio3

Kinase6

Dehydrogenase complex2

Enzymes4

Alanine3

Intracellular1

Tricarboxylic3

Glycolysis2

Serum4

Lyase4

Lactic2

Ratios1

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