DiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureInformation ScienceHealth Care
Fluorescence Polarization ImmunoassayFluorescence PolarizationImmunoassayEnzyme Multiplied Immunoassay TechniqueDigoxinSolanineChromatography, High Pressure LiquidAutoanalysisBlood StainsPhenytoinSubstance Abuse DetectionReagent Kits, DiagnosticGentamicinsRadioimmunoassayVancomycinQuality ControlCyclosporinsSpectrometry, FluorescenceGas Chromatography-Mass SpectrometryTeicoplaninImmunoenzyme TechniquesDrug MonitoringBiological AssayFluorescenceDiphenylhexatrieneHomocysteineFalse Negative ReactionsTheophyllineCross ReactionsCyclosporineSensitivity and SpecificityFetal Organ MaturityFluorescent Antibody TechniqueReproducibility of ResultsFluorescent DyesMembrane FluidityAnti-Bacterial AgentsMicroscopy, FluorescenceFluoresceinsMicroscopy, PolarizationGastric LavageBradycardiaCharcoalEncyclopedias as TopicElectric CountershockCardenolides
AssaysDetectionFPIAAssayELISATime-resolvedSerumAnalyzerMicroscopyTherapeuticLuminescenceDiagnosticsHydrogenFlowUrineDeviceProteinPlasmaParticlesMembraneMethodPregnancyHighProteinsImmune systemCellBiologicalResearchersBloodMechanismCreatinineTotalStudyDevelopmentEffectsDrugEffectImportantControlsLevelPhysical
Assays10
  • Current enzyme multiplied immunoassay technique (EMIT) assays for caffeine, amikacin, and MTX lack low-end precision. (elsevierpure.com)
  • The OIE Manual of Diagnostic Tests and Vaccines for Terrestrial Animals recommends the use of four serological tests to rule out brucellosis in international animal trade: the buffered Brucella antigen tests (rose bengal test and buffered plate agglutination test), the complement fixation test (CFT), the enzyme-linked immunosorbent assays (ELISA) and fluorescence polarization assay (FPA). (journalveterinariya.ru)
  • FP Fluor™ superior fluorescent labelling dyes, optimised for developing fluorescence polarisation-based assays. (stratech.co.uk)
  • Beckman Coulter Life Sciences' Valita Titer assays range are rapid, high throughput IgG quantification assays which use fluorescence polarization (FP) for detection. (mybeckman.ca)
  • Using the sensors and instrumentation, we are exploring new applications for optical biosensor technology including protein microarrays, biosensor/mass spectrometry systems, and microfluidics-based assays using nanoliter quantities of reagents. (illinois.edu)
  • This generic type of device includes immunoassays and chromatographic assays for tacrolimus. (medicregister.com)
  • 1514 Eisenhower Place Ann Arbor, MI 48108-3284, USA Arbor Assays builds the highest quality detection and immunoassay products for clinically important biomolecules. (contractresearchmap.com)
  • 6859 Quality Way Portage, MI 49002 Eurofins AvTech Labs offers a range of analytical and bioanalytical services including in vitro ADME assays, in vivo PK, bioanalysis, immunoassay development and biomarker ID and GMP method development. (contractresearchmap.com)
  • Used in cell viability assays and "Live-Dead" assay systems, especially automated cell viability assays. (adipogen.com)
  • Standard protein purification and characterization techniques, enzyme activity assays, as well as immunoassays (ELISA) will also be taught. (uaeu.ac.ae)
Detection10
  • The specific monoclonal antibody and the fluoresceinated SAH analog tracer constitute the FPIA detection system. (cdc.gov)
  • Currently, clinical methods for detecting PROM include mirror examination, pH paper detection, early pregnancy β-HCG paper detection, and HCG fluorescence polarization immunoassay (FPIA) detection. (cusagivd.com)
  • Nevertheless, the facts of detection of the pathogen in animals with pathologies of the reproductive system, udder pathologies, from animals with bovine leukemia made researchers think about the mechanisms of transmission of the virus and, most importantly, about its etiological role in the structure of infectious pathology of cattle. (journalveterinariya.ru)
  • AAT Bioquest are well known for their photometric detection fluorescence and luminescent technologies. (stratech.co.uk)
  • In particular, we are working on biosensors based upon photonic crystal concepts that can either be built from low-cost flexible plastic materials, or integrated with semiconductor-based active devices, such as light sources and photodetectors, for high performance integrated detection systems. (illinois.edu)
  • It has a strong blue fluorescence and can be used to create blue fluorescent bioconjugates or labeling synthetic peptides for high-throughput detection. (adipogen.com)
  • In both fluorescence NTA and EVQuant, adding 0.01% SDS maintained uEV integrity and increased aquaporin-2 detection. (exosome-rna.com)
  • It was used to determine the concentration detection limit of Rhodamine 6G in water which was found to be 0.5 mg/L. This proof of concept paves the way to in-the-field absorption spectroscopy for quick information gathering. (qdtrh.com)
  • Microscopy systems using smartphone cameras coupled with an algorithm have been demonstrated to count white or red blood cell2 for blood sample analysis as well as detection of parasites3, bacteria4,5 and viruses6. (qdtrh.com)
  • Plasmonic resonance systems can be coupled with spectroscopy to detect agents that are transparent to the optical bandwidth of the camera and offer low concentration detection level of analyte in water (100 picogram/mL) of staphylococcal enterotoxin B as reported in12. (qdtrh.com)
FPIA1
Assay4
  • They include a fluorescence polarisation immunoassay, which uses a fluorescent dye to detect cortisol in water, and a labeled-antibody assay, which relies on antibodies bound to fixed cortisol. (charlesreedcagle.com)
  • Here the PHERAstar ® FS HTS microplate reader is used in a time-resolved fluorescence assay to study the loss of membrane integrity. (bmglabtech.com)
  • In this assay, target cells are loaded with fluorescence enhancing ligand, BATDA, which penetrates the cell membrane quickly and is hydrolyzed to form a hydrophilic ligand (TDA) that is released from cells only after cytolysis (Figure 1). (bmglabtech.com)
  • We build robust immunoassay and enzyme activity kits to quantitate biomolecules in biological matrices, provide custom assay testing services, and offer world-class customer support. (contractresearchmap.com)
ELISA1
  • Our pre-activated HRP-NHS ester is ideal for labeling antibodies with HRP enzymes in a simple and efficient manner for use in ELISA and other immunoassay applications. (aatbio.com)
Time-resolved1
  • Urine particles were quantified in whole urine using nanoparticle tracking analysis (NTA), time-resolved fluorescence immunoassay (TR-FIA), and EVQuant, a novel method quantifying particles via gel immobilization. (exosome-rna.com)
Serum7
  • Increased concentrations of methylmalonic acid in plasma or serum and excessive urinary excretion of MMA are believed to be direct measures of tissue stores of cobalamin (vitamin B12) and to be the first indication of cobalamin deficiency. (cdc.gov)
  • The concentration of MMA in plasma or serum was found to be a useful indicator of cobalamin deficiency, especially in patients with few or no hematological abnormalities, normal results for the Schilling test, or normal or only slightly depressed serum cobalamin concentrations. (cdc.gov)
  • Most patients did not achieve peak or sustained serum values in the 10-20 microg/ml serum concentration range associated with antipyresis. (asahq.org)
  • The current recommended rectal acetaminophen dose of 10-15 mg/kg yields peak serum concentrations less than the antipyretic serum concentration of 10-20 microg/ml. (asahq.org)
  • Vancomycin serum concentrations were measured by fluorescence polarization immunoassay. (unibo.it)
  • Given the wide simultaneous use of vancomycin and dopamine and/or dobutamine and/or frusemide in patients admitted to intensive care units, clinicians must be aware of possible subtherapeutic serum vancomycin concentrations when these drugs are coadministered. (unibo.it)
  • 2001 ). Stimulated by these findings, we studied the clinical effect of VPA at serum concentrations of 50-100 μg/ml in 23 patients with AML or MDS as monotherapy or in combination with (ATRA) (Kuendgen et al. (biomedcentral.com)
Analyzer1
Microscopy3
  • The reagents are used as probes, stains, markers, NIR-labels, pH-sensors, ion indicators, chelators and in other applications (e.g. analytical biochemistry, immunoassays and microscopy) by life science researchers in academia, biotechnology and the diagnostics & pharmaceutical industry. (adipogen.com)
  • This dye is commonly used for quantitating double-stranded DNA (dsDNA) of viable cells without detergent treatment or fixation and for fluorescence microscopy or flow cytometry. (adipogen.com)
  • Can be used to monitor cells by flow cytometry or fluorescence microscopy. (adipogen.com)
Therapeutic1
Luminescence1
Diagnostics1
  • Within- and between-day imprecision were less than 6% for low to high concentrations of caffeine and amikacin controls and are less than 7.5% for MTX concentrations greater than 0.3 μmol/L and 12.3% at 0.06 μmol/L. The correlation coefficients for caffeine, amikacin, and MTX plotted for the Dimension RxL Max versus the methods used at Quest Diagnostics were 0.973, 0.986, and 0.992, respectively. (elsevierpure.com)
Hydrogen3
  • The effect of hydrogen gas on the impedance behavior of the sensor at different concentrations is shown in Figure 6. (plasignaling.com)
  • When p = 1, the equation represents the characteristics of a capacitor with A = C. The values noted in Table 1 shows that the resistance R gb was varied because of the flow of different hydrogen concentrations. (plasignaling.com)
  • It is related to acidity measurements in most cases by pH = log 1/2[1/(H+)], where (H+) is the hydrogen ion concentration in gram equivalents per liter of solution. (lookformedical.com)
Flow1
  • We postulate that these drugs with important haemodynamic effects may enhance vancomycin clearance by inducing an improvement in cardiac output and/or renal blood flow, and/or by interacting with the renal anion transport system, and thus by causing an increased glomerular filtration rate and renal tubular secretion. (unibo.it)
Urine4
  • A multilevel regression analysis was performed to test for differences in the cortisol concentrations in urine and saliva before and after fishing in the Barents Sea. (charlesreedcagle.com)
  • The concentration of IGFBP-1 in amniotic fluid is 100-1000 times higher than that in urine and blood. (cusagivd.com)
  • Urine particle and creatinine concentrations were highly correlated in the water-loading study ( R 2 0.96) and in random spot urines from healthy subjects ( R 2 0.47-0.95) and patients ( R 2 0.41-0.81). (exosome-rna.com)
  • uEV concentration is highly correlated with urine creatinine, potentially replacing the need for uEV quantification to normalize spot urines. (exosome-rna.com)
Device3
  • A hemodialysis system and accessories is a device that is used as an artificial kidney system for the treatment of patients with renal failure or toxemic conditions and that consists of an extracorporeal blood system, a conventional dialyzer, a dialysate delivery system, and accessories. (medicregister.com)
  • A tacrolimus test system is a device intended to quantitatively determine tacrolimus concentrations as an aid in the management of transplant patients receiving therapy with this drug. (medicregister.com)
  • The battery-powered device is also exempt from the current good manufacturing practice requirements of the quality system regulation in part 820 of this chapter, with the exception of 820.180, with respect to general requirements concerning records, and 820.198, with respect to complaint files. (medicregister.com)
Protein2
  • Stock solutions with a 1 μM concentration were prepared for each protein, both labelled and unlabeled. (bmglabtech.com)
  • Hydrolysis competes with the primary amine reaction as the pH of the system increases resulting in less efficient crosslinking of protein targets. (aatbio.com)
Plasma2
  • The plasma concentration obtains its maximum at twenty minutes after oral intake (half-life of about 2 hours, but half-life after IV administration is half an hour). (wikipedia.org)
  • We compared training load and analyzed changes in plasma concentrations of Hcy before and after the intervention. (biomedcentral.com)
Particles2
  • The concentration and size distribution of particles in beer may be measured using the Coulter Principle also known as the Electrical Sensing Zone (ESZ) method. (beckman.com)
  • A suitable electrolyte solution is required to perform the analysis.The sample is prepared by dissolving a certain volume of beer in the electrolyte and then analyzed using a Beckman Coulter Multisizer 3 to determine the size distribution and concentration for the particles present in the beer. (beckman.com)
Membrane2
  • Variations in membrane water content cause blue shifts in the laurdan emission spectrum, which are quantified by calculating the generalized polarization (GP). (adipogen.com)
  • These calcium channels mediate the influx of calcium ions into a cell upon membrane polarization. (antibodiesinc.com)
Method1
  • A key factor of the Job plot also called the continuous variation method, is that the total concentration of the 2 molecules is held constant 2 . (bmglabtech.com)
Pregnancy2
  • After pregnancy, the concentration of IGFBP-1 begins to rise. (cusagivd.com)
  • Considering the increased exposure to the health care system during a GDM-affected pregnancy, there are opportunities to address barriers among women with GDM across different race-ethnic groups. (cdc.gov)
High4
  • This might be by virtue of the high estrogen concentration with the disease, which leads to malignant proliferation of endometriotic cysts, or be due to mutations in the ARID1A gene and consequent loss of BAF250a expression. (endometriosi.it)
  • Has a relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility. (adipogen.com)
  • It shows a high extinction coefficient, polarity-dependent fluorescence and short excited-state lifetime. (adipogen.com)
  • Introduction An important yet understudied component of postpartum type 2 diabetes risk reduction among high risk women is experiences with the healthcare system. (cdc.gov)
Proteins1
  • The fluorescence of this environment-sensitive dye is greatly enhanced when incorporated into membranes or bound to lipophilic biomolecules such as proteins. (adipogen.com)
Immune system5
  • Getting out on the water and fishing can benefit your health, from boosting your immune system to improving your mental health . (charlesreedcagle.com)
  • Boosting your immune system isn't as complicated as it sounds. (charlesreedcagle.com)
  • Eating lots of fruits and vegetables is an excellent boost to your immune system. (charlesreedcagle.com)
  • Other ways to strengthen your immune system include taking vitamin supplements. (charlesreedcagle.com)
  • One common example of cell death in a mixed cell population occurs in the process termed immunosurveillance in which cells of the immune system, such as cytotoxic T lymphocytes (CTLs) and Natural Killer (NK) cells, induce apoptosis of target cells. (bmglabtech.com)
Cell1
  • It was shown that in breast cancer cells, increasing concentration of estrogens induce increasing levels of granzyme B inhibitor and SerpinB9/Proteinase Inhibitor 9 (PI-9), while progressively blocking cell death induced by NK92 natural killer cells. (bmglabtech.com)
Biological1
  • The chemical alteration of an exogenous substance by or in a biological system. (lookformedical.com)
Researchers2
  • In particular, the researchers considered the possibility of using a cap-and-trade system. (charlesreedcagle.com)
  • Our advanced methods and platform provide researchers with the most advanced and secure tools to understand underlying phenomena at a systems biology level while minimizing false positives. (contractresearchmap.com)
Blood4
  • In one fatality, the blood concentration of oleandrin and a related cardiac glycoside from the oleander plant was estimated at 20 ng/ml. (wikipedia.org)
  • Three days of starting combined therapy, cyclosporine blood concentration (CBC) decreased a 63% and was necessary to increase the cyclosporine dose. (journalmc.org)
  • Blood from a patient flows through the tubing of the extracorporeal blood system and accessories to the blood compartment of the dialyzer, then returns through further tubing of the extracorporeal blood system to the patient. (medicregister.com)
  • 1) Class II (performance standards) for hemodialysis systems and all accessories directly associated with the extracorporeal blood system and the dialysate delivery system. (medicregister.com)
Mechanism4
  • Generally, the conduction process (R) and polarization behavior (C) become dominant in sensing mechanism. (plasignaling.com)
  • a component of a machine that is responsible for moving and controlling a mechanism or system, for example by opening a valve . (genomicglossaries.com)
  • An actuator is the mechanism by which a control system acts upon an environment. (genomicglossaries.com)
  • Describe the kinetics, mechanism and role of enzymes in living systems. (uaeu.ac.ae)
Creatinine1
  • Then he was admitted into hospital with a creatinine plasmatic concentration of 1.9 mg/dL and creatinine clearence of 42.41 mL/min. (journalmc.org)
Total1
  • Docetaxel area under the curve (AUC) and maximum concentration (Cmax) in each cycle and total cumulative AUC (AUCcum) were calculated and related to the incidence of adverse effects and tumour recurrence. (unav.edu)
Study1
  • The aim of this study was to evaluate retrospectively the importance of a Bayesian pharmacokinetic approach for predicting vancomycin concentrations to individualize its dosing regimen in 18 critically ill patients admitted to intensive care units following cardiothoracic surgery. (unibo.it)
Development1
  • Within the NMR Facility I have many roles, everything from the development and implementation of new NMR experiments to keeping the systems alive and the computers running. (edu.au)
Effects1
  • It has also been used in aquaculture studies to investigate the effects of rearing conditions on cortisol concentrations. (charlesreedcagle.com)
Drug2
  • Cyclosporine, has been widely used as immunosuppressant, is metabolized by intestinal and hepatic cytochrome p450 system and is a substrate of the P-glycoprotein transport system, which results in numerous drug interactions [ 1 ]. (journalmc.org)
  • The methods and systems developed in the laboratory are applied in the fields of life science research, drug discovery, diagnostic testing, and environmental monitoring. (illinois.edu)
Effect2
  • CBC is liable to change in patients treated with drugs metabolized by cytochrome p450 system, and the effect and magnitude of a multiple interaction is unpredictable. (journalmc.org)
  • The rotation of the molecules between absorption and emission of the photon has the effect of "twisting" the polarization of the light. (mybeckman.ca)
Important2
  • The thyroid is a very important gland in the body, belonging to the endocrine system. (cusagivd.com)
  • The determination of particle concentration in beers is important for evaluating and/or correcting several steps during the brewing process and finishing of the product. (beckman.com)
Controls1
  • The dialysate delivery system controls and monitors the dialysate circulating through the dialysate compartment of the dialyzer. (medicregister.com)
Level1
  • Spectroscopy systems capable of measuring the water pH level have been also demonstrated with a resolution of 0.305 nm/pixel10. (qdtrh.com)
Physical2