Concentration solubility. Medical search. Frequent questions

thus, an acidic environment decreases solubility. (medscape.com)
This means that as the enzyme concentration decreases, the reaction rate will decrease. (meltingpointathens.com)
Also, as water temperatures increase, the oxygen solubility decreases, which can further reduce DO concentrations. (ceh.ac.uk)
Acalabrutinib solubility decreases with increasing gastric pH. (medscape.com)

Differences in P solubility in biosolids from differing WWTP processes clearly influenced P solubility in amended soils, as well as the magnitude of soluble and bioavailable P concentrations in surface runoff. (usda.gov)
Differences in the properties of organic phosphorus (P) sources, particularly those that undergo treatment to reduce soluble P, can affect soil P solubility and P transport in surface runoff. (usda.gov)
Throughout the study, application of lime-stabilized biosolids and poultry litter increased concentrations of soil soluble P, readily desorbable P and soil P saturation resulting in increased DRP and FeO-P concentrations in runoff. (usda.gov)

The equilibrium of CO2 and carbamate concentration data for the absorption of CO2 in aqueous solutions of single and mixed amines was analyzed using the Deshmukh-Mather model. (um.edu.my)
We need concentrations of phosphorus that are higher than its equilibrium solubility in silicon. (eurekalert.org)
But it is noted that a minimum of 30 minutes is required for settling time to avoid significant effect on the equilibrium concentration. (aiche.org)
We report on highly Mn-doped GaAs nanowires (NWs) of high crystalline quality fabricated by ion beam implantation, a technique that allows doping concentrations beyond the equilibrium solubility limit. (lu.se)
article{1e6d9f06-8742-4c5a-87af-e60b3040df47, abstract = {{We report on highly Mn-doped GaAs nanowires (NWs) of high crystalline quality fabricated by ion beam implantation, a technique that allows doping concentrations beyond the equilibrium solubility limit. (lu.se)

The water solubility of aluminium chloride hydroxide sulphate (as aqueous solution) was investigated according to OECD/EC guidelines. (europa.eu)

solubility - the maximum amount of a substance that can be dissolved in a given quantity of solvent at a given temperature to produce a saturated solution. (gpb.org)
It is very volatile, readily producing flammable and toxic concentrations at room temperature. (cdc.gov)
Hydrogen cyanide is very volatile, producing potentially lethal concentrations at room temperature. (cdc.gov)
Data on CO2 loading in aqueous solutions of DEA and MDEA and their mixtures at various temperature (303-323 K) and CO2 partial pressure (0.09-100 kPa) together with carbamate concentrations in case of DEA and its mixtures with MDEA were fitted simultaneously to generate the different interaction parameters required to calculate the activity coefficients in the model. (um.edu.my)
The rate of chemical reactions can be altered by changing pH, temperature, and/or the substrate concentration. (meltingpointathens.com)
The effects of hbr concentration and temperature on the solubility and hydration state of albr3, cob, pbbr2, mnbr2, kbr, and nabr were investigated by the Bureau of Mines. (cdc.gov)

Hydrogen cyanide has a distinctive bitter almond odor, but some individuals cannot detect it and consequently, it may not provide adequate warning of hazardous concentrations. (cdc.gov)
The odor of hydrogen cyanide is detectable at 2-10 ppm (OSHA PEL = 10 ppm), but does not provide adequate warning of hazardous concentrations. (cdc.gov)
OSHA PEL = 10 ppm), but does not provide adequate warning of hazardous concentrations . (cdc.gov)
Odor does not provide any warning of hazardous concentrations. (cdc.gov)
Ethylene glycol is odorless and thus, odor does not provide any warning of hazardous concentrations . (cdc.gov)

The solvent used for solubility test can be customized. (genscript.com)
Adare leveraged its solvent-han-dling capability, which is a natural ex-tension of Adare's Microcap ® technology, using cyclohexane to overcome the solubility challenge through the well-established solid dis-persion/solid solution approach," says Dr. Lai. (drug-dev.com)

Colligative properties of solutions-freezing point depression, boiling point elevation, and vapor pressure lowering-are related to the concentration of solute molecules but independent of the specific solute type. (visionlearning.com)

The relative solubility of a salt or polar compound in water is a balance of two forces: the attraction between atoms of the salt molecule, and the attraction between the ions and the water molecules. (visionlearning.com)
In this module, we'll look at what actually happens when a compound dissolves, why some things dissolve more easily than others, and how the Romans might have been able to use knowledge of solubility to remove the lead from their water. (visionlearning.com)
The test substance was mixed with water at the maximum concentration of 1000 g/L, and found to be totally miscible. (europa.eu)
The test media with the test concentrations of 3.2 to 100 mg/L were turbid and homogeneous dispersions in the test water on Day 0. (europa.eu)
The combination of elevated nutrient concentrations, water temperatures, and sunlight, alongside low river flows, can result in algal blooms which shade out and outcompete submerged aquatic plants. (ceh.ac.uk)
Conversely, summer droughts often result in excessive algal growth due to low river flows and high sunlight, which increase oxygen concentrations in the water due to photosynthesis. (ceh.ac.uk)
For the Congo red test, a maceutical-grade oseltamivir phosphate was graciously portion of material from each sample group was weighed, donated by Hoffman-La Roche Ltd. We purchased Congo and enough water was added to achieve a concentration red (dye content 97%), bromochlorophenol blue sodium of 6.5 mg/mL. (cdc.gov)
The ionized form has low lipid solubility (but high water solubility-ie, hydrophilic) and high electrical resistance and thus cannot penetrate cell membranes easily. (msdmanuals.com)
The specimens were desiccated, kept in water at 37 °C for 7 days and desiccated again to calculate water sorption, solubility and mass variation. (bvsalud.org)

This is supported by the fat solubility of the substance and measured concentrations in surface waters. (janusinfo.se)

Solubility data for selected salts is given together with their solubility curves graphical representation and how to do simple solubility graph reading and mass of salt crystallising calculations. (docbrown.info)
These revision notes, data tables and solubility curve graphs of various compounds including salts, should prove useful for the new AQA chemistry, Edexcel chemistry & OCR chemistry GCSE (9 1, 9-5 & 5-1) science courses. (docbrown.info)

Drugs that alter pH of upper GI tract may alter the solubility of erlotinib and reduce its bioavailability. (medscape.com)
The virtual 2020 Global Drug Bioavailability Enhancement Summit this past December showcased novel technologies and platforms aimed at addressing bioavailability and solubility challenges. (drug-dev.com)
The driver for novel strategies to resolve solubility issues, with a target of improving bioavailability, often stems from a requirement to get more information about the key relationships using less API, in a reduced time frame," says Andrew Parker, PhD, Director Open Innovation, Small Molecules, Oral and Speciality Drug Delivery, Catalent. (drug-dev.com)
This annual Drug Development & Delivery report introduces readers to some novel approaches to improving bioavailability and solubility that have one commonality: they treat each molecule as unique. (drug-dev.com)
Where drug solubility is inade-quate to generate the necessary driv-ing force for drug release, it creates a typical 'no release, no bioavailability' situation, explains Dr. Lai. (drug-dev.com)
A second approach to overcome solubility/bioavailability is to enhance solubility by adapting solid dispersion/solid solution technology to the Diffucap concept. (drug-dev.com)
Adare also announced the launch of a small non-GMP laboratory for the exploration of various technologies that may be suitable for solubility/ bioavailability enhancement. (drug-dev.com)

Soils that received Fe amended biosolids consistently produced the lowest concentrations of dissolved and bioavailable P in runoff. (usda.gov)
Due to technical reasons, the dispersions with the lowest concentrations of 0.32 and 1.0 mg/L were prepared as dilutions of the WAF with the concentration of 3.2 mg/L. (europa.eu)

Further increases in solubility were obtained by the addition of the NVoy polymer reagent to the reaction mixture. (iucr.org)
Further increases in hbr concentration increased cobr2 solubility because of the formation of bromide complexes. (cdc.gov)

Phosphorus speciation in the biosolids and poultry litter differed due to treatment processes and significantly altered soil P solubility and dissolved reactive P (DRP) and bioavailable P (FeO-P) concentrations in surface runoff. (usda.gov)
But as microchips continue to shrink, the silicon must be doped, or mixed, with higher concentrations of phosphorus to produce the desired current. (eurekalert.org)

In addition, mechanical stirring, filtering and gravimetrical options were chosen to measure the solubility data of form II for a comprehensive understanding of solubility curves of CBZ form II and III. (aiche.org)

If solubility problems occur with your SNAP-tag fusion protein, we recommend testing a range of pH (pH 5.0-pH 10.0) and ionic strengths. (neb.com)
If solubility problems occur, we recommend testing a range of pH (pH 7.0-pH 8.0) and ionic strengths. (neb.com)

Molarity is a measure of the solute concentration in a solution, and remains consistent when a fraction of the solution is poured off. (visionlearning.com)
http://lxsrv7.oru.edu/~alang/onsc/solubility/allsolvents.php?solute=capsaicin ) and many chlorinated hydrocarbon solvents (e.g. chloroform) are teratogenic and/or mutagenic. (thehotpepper.com)

Dissolved and bioavailable P concentrations were initially most elevated by PL application but by the second year lime stabilized biosolids amended soils contributed the highest concentrations, likely due to the dissolution of calcium P minerals from the biosolids over time. (usda.gov)
This two year field study investigated soil P solubility and runoff P losses from two agricultural soils in the Mid-Atlantic region following land application of biosolids derived from different wastewater treatment processes and poultry litter. (usda.gov)
Acidification of cadmium-containing soils and sediments may increase the concentrations of cadmium in surface waters and crops. (inchem.org)

will increase the solubility of the gas in the polymer. (scirp.org)
When enhanced solubility is neces-sary, the binder polymer is strategically selected based on its ability to form a solid dispersion/solid solution with the drug, usually through a sol-vent system. (drug-dev.com)

Use mathematics and computational thinking to compare, contrast, and evaluate the nature of acids and bases in terms of percent dissociation, hydronium ion concentration, and pH. (gpb.org)

Substantial absorption can occur through intact skin if vapor concentration is high or with direct contact with solutions, especially at high ambient temperatures and relative humidity. (cdc.gov)

Mannitol will be present at 10 mM final concentration and should not lead to any problems. (neb.com)

Runoff total P (TP) concentrations were closely related to sediment transport. (usda.gov)
Over time, as sediment transport declined and DRP concentrations became an increasingly important component of runoff FeO-P and TP, total runoff P was more strongly influenced by the type of biosolids applied. (usda.gov)

The dissolved oxygen concentration measured in the blank and test item vessels at pH 6 varied from 8.42 to 8.51 mg/L O2. (europa.eu)
Fish and aquatic insects depend on adequate dissolved oxygen (DO) concentrations to survive. (ceh.ac.uk)

We provide you with a complete, customized dissolution profile of your peptide , including a report containing the gross peptide concentration of your peptide and the solvents your peptide dissolves in best. (genscript.com)

The determination of an accurate solubility curve is critical for efficient design of the crystallization process. (aiche.org)

The SNAP-tag activity is not affected by this concentration of Tween 20. (neb.com)
At this concentration Tween 20 does not affect the performance of the SNAP-tag. (neb.com)

Accuracy of protein concentration is essential. (ornl.gov)
The acquisition of bioprocess information, however, still requires a lot of sampling to perform offline analysis of biomass and protein concentration, as well as byproduct concentrations. (genengnews.com)

For measurement of the actual concentrations of the test item, duplicate samples were taken from the test media of all test concentrations at the start of the test (without algae) and at the end of the test (containing algae). (europa.eu)
However, there are various solubility measurement techniques. (aiche.org)

Biomass concentration, pH and DO values, and three fluorescence signals can all be measured in parallel. (genengnews.com)
However, when algal blooms terminate, DO concentrations can rapidly fall as the algal biomass is consumed by respiring bacteria, and this can lead to fish kills and localised extinctions of some aquatic species. (ceh.ac.uk)

Thus, the proteins that transport zinc likely facilitate cell signaling processes that contribute to glycemic control in peripheral tissues by modulating cytosolic zinc concentrations. (hindawi.com)
In the presence of high concentrations of inert macromolecules, the self-association of proteins is strongly enhanced through an entropic, excluded-volume effect variously called macromolecular crowding or depletion attraction. (lu.se)

Unfortunately, chemical analysis of these signal compounds have often been proven to be a great challenge, partially because these chemicals exist at very low concentration in insects. (usda.gov)

For quantitative solubility test, the default testing start at a maximum concentration of 20mg/mL, if you need higher concentration test please contact us for detail. (genscript.com)

In Sweden haloperidol has been reported in wild fish and treated wastewater exposed fish at levels around therapeutic concentrations in humans. (janusinfo.se)

Increased plasma concentrations of ranolazine which may increase the potential for serious and/or life-threatening reactions (see section 4.5). (who.int)

The differences in soil P solubility were generally mirrored in runoff P concentrations. (usda.gov)
The results of this study indicate that nutrient management plans must account for both the differences in the properties of treated biosolids and their effect on soil P saturation and solubility. (usda.gov)
The shake-flask method was performed as the base scenario to examine solubility differences by two off-line sampling separation techniques: (1) centrifuging or (2) filtering. (aiche.org)

What is the relationship between the reaction rate and enzyme concentration? (meltingpointathens.com)
For an enzyme-catalysed reaction, there is usually a hyperbolic relationship between the rate of reaction and the concentration of substrate, as shown below: (A) At low concentration of substrate, there is a steep increase in the rate of reaction with increasing substrate concentration. (meltingpointathens.com)

Solubilities in solutions sparged to hbr saturation at 20 deg c were, in percent, 0.5 For albr3, 42.0 For cobr2, 32.2 For pbbr2, 21.0 For mnbr2, 0.6 For kbr, and 0.3 For nabr. (cdc.gov)
At 60 deg c, the solubilities at hbr saturation were, in percent, 1.8 For albr3, 41.4 For pbbr2, 1.3 For kbr, and 0.4 For nabr, cobr, precipitated out to a minimum solubility of 27.2 pct at 28.7-Pct-hbr concentration. (cdc.gov)

Using the generated interaction parameters, the model was applied to correlate the CO2 loading in solutions of DEA and MDEA and their mixtures reported in the literature as well as those obtained in our laboratory and was found to be able to give a good estimation of CO2 loading and carbamate concentration over a wide range of operating conditions in both single and mixed amine solutions. (um.edu.my)
Evidence of undissolved material (e.g. precipitate, surface film, etc): The test media with the test concentrations of 0.32 and 1.0 mg/L were clear solutions throughout the test period. (europa.eu)
An overview of the stock solutions on the worktable and the required volumes and concentrations can be printed. (genengnews.com)

[ 4 ] When urate is filtered at exceedingly high concentrations from the plasma and is further concentrated through the course of the tubular system, with the pH becoming progressively more acidic, uric acid precipitation and obstruction in the tubules, collecting ducts, and even pelves and ureters may result. (medscape.com)
These wells draw primarily from bedrock aquifers where high concentrations of naturally-occurring arsenic are common. (confex.com)
The concentration was determined by three quantification techniques: (1) off-line gravimetrically, or (2) off-line high liquid chromatography method (HPLC) or (3) on-line Raman method. (aiche.org)
Oseltamivir and zanamivir are both well as a high-performance liquid chromatographic method approved by the Food and Drug Administration (FDA) for (HPLC), to measure the concentration of oseltamivir phos- use in controlling both infl uenza A and B viruses ( 1 ). (cdc.gov)
Drugs diffuse across a cell membrane from a region of high concentration (eg, gastrointestinal fluids) to one of low concentration (eg, blood). (msdmanuals.com)

Solubility data is important for pharmaceutical formulation and process design. (aiche.org)
For example, solubility data is essential for estimating the supersaturation and understanding the relative stability of crystal forms. (aiche.org)
Here we will evaluate several popular ones and discuss how to obtain accurate solubility data. (aiche.org)
The goal was to evaluate the effect of (a) dissolving methods, (b) sampling separation, and (c) quantification technique on the accuracy of solubility data. (aiche.org)

The salt concentration may also need to be optimized for your particular fusion protein (50-250 mM). (neb.com)

Our peptide solubility test is a unique solution to help you conserve time, money, and your peptide stock, allowing you to easily determine the condition that both dissolves your peptides to the highest concentration and suits your assay requirements. (genscript.com)
You will received a customized solubility test report containing the specific concentration of your peptide in each of the tested solvents. (genscript.com)
View your solubility test results any time by logging into your Account page. (genscript.com)
All the solubility test results are based on gross peptide weight (include peptide, salt, moisture and impurity etc..), please choose Peptide Content Analysis service for precise target peptide concentration. (genscript.com)
Former free solubility test is upgraded into Qualitative solubility test and the upgrade is launched from 10/27/2022. (genscript.com)
Crude peptides, desalt peptides and peptide libraries are not eligible for a free solubility test. (genscript.com)
At the lowest test concentration of 0.32 mg/L the measured concentration of the test item was lower than LOQ (LOQ=0.981 mg/L) at the start and end of the test. (europa.eu)
For the characterization of the WAFs, duplicate samples were taken from the test media of all test concentrations at the start of the test (without algae, 100 and 7.5 mL volume) and at the end of the test, with algae (100 mL and 7.5 mL volume). (europa.eu)
One sample without algae (7.5 mL volume) of all test concentrations and control was also taken at the end of the test. (europa.eu)

In most biological environments, the concentration of the enzyme is lower than the concentration of the substrate. (meltingpointathens.com)
One ap-proach to overcome such a pH-dependent solubility issue in the case of an alkaline drug is to use an organic acid as the drug core or an acid layer prior to using it as the substrate for the drug layer, which is then followed by a rate-controlling membrane. (drug-dev.com)

Simulations were unable to capture the wide diurnal range of observed continuous DO and phytoplankton concentrations, potentially suggesting the need for improved understanding of processes at this time scale. (mdpi.com)

In the medium library, all media components used in the laboratory can be entered with their lot number and solubility. (genengnews.com)

During a year of sampling, none of the samples from the shallow wells had detectable concentrations of arsenic, at a reporting limit of 0.5 µg/L. The project also included two samplings of a bedrock well, proximal to the shallow well locations, both of which resulted in elevated arsenic concentrations. (confex.com)

Because normal plasma levels of urate are 3-7 mg/dL for men and 2-6 mg/dL for women, the solubility limit apparently is approached under physiologic conditions. (medscape.com)

Based on time-weighted mean measured concentration of C12 component (mg a.i. (europa.eu)

Urinary and blood cadmium concentrations are generally much lower in non-occupationally exposed people, for whom the most important sources of exposure are cigarette smoking and, especially in polluted areas, eating certain foods (e.g. rice). (inchem.org)

Refinement of extracts is essentially 'extracting from extracts' which involves separation of some of the dissolved components from others, and the basic principle is equally simple: solubility. (thehotpepper.com)

In contrast to most manures which are not chemically treated, wastewater treatment plant (WWTP) processes, such as metal salt amendment or lime stabilization, may influence soil P solubility and affect the risk of P loss in surface runoff. (usda.gov)

Plasma at a pH of 7.40 is saturated with urate at a concentration of 7 mg/dL. (medscape.com)
In tissues, zinc concentration is highest in the prostate (approximately 200 μ g/g), then pancreas (approximately 140 μ g/g), and muscle (approximately 50 μ g/g), while in plasma there is approximately 14-16 μ M of total zinc that is distributed to cells [ 19 ]. (hindawi.com)
Given the low plasma concentration of zinc and its importance in cellular signaling, it is essential that the availability and distribution of "free" zinc (free zinc is used to differentiate zinc involved in cell signaling from zinc that tightly bound to protein and therefore thermodynamically unavailable) are tightly controlled [ 6 ]. (hindawi.com)
Pethidine, piroxicam, Increased plasma concentrations of norpethidine, propoxyphene piroxicam and propoxyphene, thereby, increasing the risk of serious respiratory depression or haematologic abnormalities, or other serious adverse effects from these agents. (who.int)
Astemizole, terfenadine Increased plasma concentrations of astemizole and terfenadine. (who.int)

Increased hbr concentration caused decreased salt solubility because of the common ion effect for all the investigated bromides except pbbr2. (cdc.gov)
This effect was dependent on the concentration of the Pluronic surfactant, which influenced diffusion to the interface between the photoresist and the bulk solution. (bvsalud.org)

Diffusion rate is directly proportional to the gradient but also depends on the molecule's lipid solubility, size, degree of ionization, and the area of absorptive surface. (msdmanuals.com)

Anatomy1

Organisms1

Chemicals and Drugs81

Analytical, Diagnostic and Therapeutic Techniques and Equipment36

Phenomena and Processes40

Disciplines and Occupations5

Technology, Industry, Agriculture22

Information Science2

Health Care2

Decreases4

Soluble3

Equilibrium5

Aqueous solution1

Temperature6

Warning of hazardous concentrations5

Solvent2

Colligative properties1

Water9

Substance1

Salts2

Bioavailability7

Lowest concentrations2

Increases2

Phosphorus2

Curves1

Problems occur2

Solute2

Soils3

Polymer2

Acids1

Occur1

Final concentration1

Sediment2

Dissolved oxygen2

Dissolution1

Determination1

Tween2

Protein concentration2

Measurement2

Biomass2

Proteins2

Chemical1

Maximum concentration1

Humans1

Reactions1

Differences3

Reaction2

Saturation2

Solutions3

High5

Data4

Salt concentration1

Test9

Substrate2

Potentially1

Laboratory1

Sampling1

Limit1

Component1

Important1

Separation1

Contrast1

Plasma5

Effect2

Diffusion1