• For all subjects ( n =38), the median baseline 25 hydroxyvitamin D (25OHD) level was 36.25 (27.5-48.12) nmol/l. (nature.com)
  • Since early human evolution occurred under UV-rich conditions, typical 25(OH)D concentrations were surely higher than 100 nmol/L [40 ng/mL]. (westonaprice.org)
  • Normal plasma levels of 25OHD are 25 to 250 nanomoles (nmol)/L (10 to 100 mcg/L) (SACN 2016). (e-lactancia.org)
  • For children and youth 1 to 18 years old, the estimated average requirement was set at 400 IU/d based on the ability to achieve a serum 25-hydroxyvitamin D level above 40 nmol/L, which is thought to be sufficient for bone health. (cmaj.ca)
  • Fortification studies in adults show that consuming 100 - 1000 IU of vitamin D each day results in increased blood concentrations by 15 to 40 nmol/L. Other data with supplements indicate that for every 100 IU of vitamin D we ingest, we raise our blood levels by 2.5 nmol/L. (precisionnutrition.com)
  • This biologic 'normal' value is greater than current population norms for 25(OH)D. Concentrations of 25(OH)D that correlate with desirable effects extend to at least 70 nmol/L, with no obvious threshold," stated R. Vieth and colleagues. (preparedfoods.com)
  • One mcg per day of vitamin D-3 (cholecalciferol) increases circulating 25(OH)D by about 1 nmol/L (0.4 ng/mL). (preparedfoods.com)
  • If 70 nmol/L is regarded as a minimum desirable target 25(OH)D concentration, then current recommendations of 15mcg per day do not meet the criterion of an RDA," the researchers concluded. (preparedfoods.com)
  • They classified these samples as follows: less than 25 nmol/L (severely deficient), 25 nmol/L or greater to less than 50 nmol/L (deficient), and 50 nmol/L or greater (sufficient). (atlaschiro.com)
  • Vitamin D deficiency is defined by most experts as a serum 25(OH)D level of less than 20 ng/mL (50 nmol/L). (medscape.com)
  • Vitamin D insufficiency has been defined as a serum 25(OH)D level of 21-29 ng/mL (52-72 nmol/L). This is based on the observed physiological changes in calcium absorption and parathyroid hormone levels that occur with changes in vitamin D levels. (medscape.com)
  • In healthy postmenopausal women with serum 25(OH)D levels averaging 34.4 ng/mL (86.5 nmol/L), intestinal calcium absorption increased from 45% to 65% compared to those with mean 25(OH)D levels of 20 ng/mL (50.1 nmol/L). (medscape.com)
  • Chapuy et al reported an inverse correlation between serum intact parathyroid hormone (iPTH) and serum 25(OH)D. Serum iPTH held a stable plateau level when serum 25(OH)D values exceeded 31 ng/mL (78 nmol/L) but started to rise when the serum 25(OH)D values fell below this level. (medscape.com)
  • Vitamin D sufficiency has been defined as serum 25(OH)D levels of 30 ng/mL (75 nmol/L) and above based on analysis of observational studies of vitamin D and various health outcomes. (medscape.com)
  • Their conclusion based on all endpoints was that 25(OH)D levels of 30 ng/mL (75 nmol/L) or greater are more effective in achieving positive outcomes than lower levels. (medscape.com)
  • The best outcomes were seen with 25(OH)D levels from 36-40 ng/mL (90-100 nmol/L). (medscape.com)
  • Vitamin D toxicity is observed when serum 25(OH)D levels are greater than 150 ng/mL (374 nmol/L). (medscape.com)
  • Vitamin D status in the elderly, seasonal substrate deficiency causes 1,25(OH)2 cholecalciferol deficiency. (nature.com)
  • D is a natural component of breast milk where it is found primarily as cholecalciferol, but also as ergocalciferol and its respective 25-hydroxylated metabolites. (e-lactancia.org)
  • Fasting blood sera were analyzed for 25(OH)D with the high-performance liquid chromatography (HPLC) and for parathyroid hormone (PTH), immunoglobulins and complement C4 and C3 concentrations with immunoassays. (biomedcentral.com)
  • On the basis of the available evidence, an association between vitamin D concentrations and birth weight, dental caries in children, maternal vitamin D concentrations at term, and parathyroid hormone concentrations in patients with chronic kidney disease requiring dialysis is probable, but further studies and better designed trials are needed to draw firmer conclusions. (bmj.com)
  • Serum concentrations of total calcium, ionic calcium, parathyroid hormone (PTH), 25-hydroxyvitamin-D3, and 1,25-dihydroxyvitamin-D3 were measured to monitor calcium homeostasis. (cdc.gov)
  • Assessment of the effectiveness and safety of high daily 125 μ g (5000 IU) or 250 μ g (10 000IU) doses of vitamin D 2 during 3 months, in rapidly obtaining adequate 25 hydroxyvitamin D (25OHD) levels. (nature.com)
  • 2. in the liver it is hydroxylated to calcifediol, also called calcidiol or 25-hydroxyvitamin D (25OHD). (e-lactancia.org)
  • All participants older than 1 year of age with serum 25-hydroxyvitamin D (25OHD) measured below the lower limit of reference range at screening should start daily Vitamin D supplementation before randomization. (who.int)
  • It is converted in the liver to calcifediol (25-hydroxyvitamin D) which is then converted in the kidney to calcitriol (1,25-dihydroxyvitamin D). One of its actions is to increase calcium uptake by the intestines. (wikipedia.org)
  • Collectively, the two forms together are referred to simply as 25-hydroxyvitamin D, also known as calcifediol or calcidiol. (creighton.edu)
  • The role of vitamin D in immunity is regulated by the availability of 25(OH)D - also known as calcifediol or calcidiol - in the bloodstream (i.e. the active form of vitamin D in the body), which is further converted to 1,25-dihydroxyvitamin D and utilized by immune cells. (dsm.com)
  • Serum circulating 25-hydroxyvitamin D (25(OH)D) level is considered as the best indicator of the body vitamin D status, and although still debated, most experts defined vitamin D deficiency as 25(OH)D levels lower than 20 ng/mL [ 4 , 5 ]. (hindawi.com)
  • For instance, in a European study involving more than 8500 postmenopausal women, the prevalence of 25(OH)D deficiency reached 32.1% when considering the cutoff value of 20 ng/mL [ 9 ], while in Indian, Chinese, and US populations of postmenopausal women, the estimated prevalence rates were 53.3%, 72.1%, and 53%, respectively [ 10 - 12 ]. (hindawi.com)
  • While even this basic practice is problematic, the extraordinary influence of what I like to call the "naked ape hypothesis of optimal serum 25(OH)D" has created a paradigm wherein "deficiency" and "insufficiency" are together seen as the norm, and 25(OH)D levels that may actually be quite dangerous - especially when not adequately balanced by other nutrients in the diet - are specifically sought out as a panacea. (westonaprice.org)
  • Furthermore, describing how vitamin D levels fluctuate month-to-month may provide a basis for implementing public health strategies to increase 25(OH)D levels when deficiency is most acute. (cdc.gov)
  • Individuals who supplement their diet with vitamin D have a significantly reduced incidence of respiratory tract infections, with some indication that the greatest positive effects of supplementation may be seen in individuals with the lowest 25(OH)D levels. (dsm.com)
  • Circulating 25(OH)D concentration was inversely associated with colorectal cancer risk for women, but not with risk of breast cancer or prostate cancer. (unboundmedicine.com)
  • Concentration of 25(OH)D in baseline-dried blood spots was measured using LC-MS/MS. Cox regression yielded adjusted HRs and 95% confidence intervals (CI) for each cancer in relation to plasma-equivalent 25(OH)D concentration. (unboundmedicine.com)
  • Design Umbrella review of the evidence across systematic reviews and meta-analyses of observational studies of plasma 25-hydroxyvitamin D or 1,25-dihydroxyvitamin D concentrations and randomised controlled trials of vitamin D supplementation. (bmj.com)
  • Results 107 systematic literature reviews and 74 meta-analyses of observational studies of plasma vitamin D concentrations and 87 meta-analyses of randomised controlled trials of vitamin D supplementation were identified. (bmj.com)
  • Plasma concentrations of 25-hydroxyvitamin D in meat eaters, fish eaters, vegetarians and vegans: results from the EPIC-Oxford study. (bvsalud.org)
  • T) Genotype Is Associated with Plasma 25-Hydroxyvitamin D Concentrations in Caucasians: A Mendelian Randomization Study. (cdc.gov)
  • 25-hydroxyvitamin D is the predominant circulating form of vitamin D found in the bloodstream, and is the form measured by medical professionals to determine a person's vitamin D status. (creighton.edu)
  • To our knowledge, this is the first Canadian study to examine the effect on 25-hydroxyvitamin D - the circulating form of vitamin D - from drinking non-cow's milk beverages. (cmaj.ca)
  • Methods: Participants of the Raine Study Generation 2 cohort had 25(OH)D concentrations measured at the 6-, 14-, 17- and 20-year follow-ups. (edu.au)
  • In a population-based cohort study, among 3825 mother-child pairs, ferritin, transferrin concentrations, and transferrin saturation were measured from maternal venous blood samples during early pregnancy. (omicsdi.org)
  • Our objective was to determine whether vitamin D2 was less effective than vitamin D3 in maintaining serum 25-hydroxyvitamin D levels or increased the catabolism of 25-hydroxyvitamin D3. (nih.gov)
  • The 25-hydroxyvitamin D3 levels did not change in the group that received 1000 IU vitamin D2 daily. (nih.gov)
  • The 1000 IU dose of vitamin D2 or vitamin D3 did not raise 25-hydroxyvitamin D levels in vitamin D-deficient subjects above 30 ng/ml. (nih.gov)
  • A 1000 IU dose of vitamin D2 daily was as effective as 1000 IU vitamin D3 in maintaining serum 25-hydroxyvitamin D levels and did not negatively influence serum 25-hydroxyvitamin D3 levels. (nih.gov)
  • Patients were assigned to Q1 group (53 cases), Q2 group (54 cases), Q3 group (53 cases), and Q4 group (53 cases) according to the quartiles of serum 25(OH)VitD levels. (shsmu.edu.cn)
  • Older people have lower 25-hydroxyvitamin D (25(OH)D) serum levels than younger adults. (biomedcentral.com)
  • We aimed to determine the levels of 25(OH)D serum concentrations in healthy senior citizens and to study their relationship to the levels of components of humoral immunity. (biomedcentral.com)
  • The relationship of the major components of the humoral system and age with 25(OH)D levels was also assessed. (biomedcentral.com)
  • About 66% of the subjects had insufficient levels of 25(OH)D. Normal levels of 25(OH)D were found in 26.1% of the subjects of which 21% were males and 30.5% were females (total study population). (biomedcentral.com)
  • Severely deficient levels of 25(OH)D were found in 7.98% of the total study population. (biomedcentral.com)
  • Serum levels of total IgA, IgG, IgG2 and IgG4 peaked together with 25(OH)D during late summer. (biomedcentral.com)
  • Although some results remain to be confirmed, low serum 25(OH)D levels have been linked to all-cause cardiovascular, cancer and infection-related mortality and also to stroke. (biomedcentral.com)
  • 20 ng/ml) serum 25(OH)D levels. (biomedcentral.com)
  • Higher maternal transferrin concentrations during pregnancy, reflecting lower serum iron levels, were associated with an increased risk of child's physician-diagnosed inhalant allergy but not lung outcomes. (omicsdi.org)
  • In the EU (except France): 20 μg/d (800 IU per day) In France: 25 μg/d (1000 IU per day) Low levels of vitamin D are more commonly found in individuals living in northern latitudes, or with other reasons for a lack of regular sun exposure, including being housebound, frail, elderly, obese, having darker skin, or wearing clothes that cover most of the skin. (wikipedia.org)
  • Indeed, this paradigm heavily influenced some of my early articles on the fat-soluble vitamins, such as my 2006 article " From Seafood to Sunshine: A New Understanding of Vitamin D Safety ," where I contributed original ideas about the interactions between the fat-soluble vitamins, but essentially took the popular ideas advocating high levels of serum 25(OH)D for granted. (westonaprice.org)
  • Dr. Vieth articulated the same hypothesis in an incredibly popular and influential 1999 article ( 2 ) wherein he provided specific data supporting the high serum 25(OH)D levels referred to in the quote above. (westonaprice.org)
  • maternal supplementation with 1,200 IU per day did assure maternal levels of 25 OHD, but not those of infants (Czech 2014). (e-lactancia.org)
  • When 25(OH)D levels in the blood are insufficient or deficient, immune responses can be limited, leading to increased risk of infection incidence and severity. (dsm.com)
  • 11 Individuals with deficient 25(OH)D levels had a 54% higher rate of a positive test than those who had adequate levels. (dsm.com)
  • A 2021 meta-analysis of 54 observational clinical studies representing 1.4 million people provided further strong evidence that low 25(OH)D levels are associated with greater COVID-19 incidence, severity and mortality. (dsm.com)
  • In a linked article, Lee and colleagues 1 describe a significant negative association between the consumption of non-cow's milk beverages and serum 25-hydroxyvitamin D levels in a large, cross-sectional sample of healthy Canadian children one to six years old. (cmaj.ca)
  • 2 Perhaps unbeknownst to parents and caregivers, fortification of non-cow's milk beverages is voluntary, 3 and not all of the products are fortified, which may have contributed to the lower 25-hydroxyvitamin D levels reported by Lee and colleagues. (cmaj.ca)
  • [ 5 , 6 ] However, lowered serum phosphate levels correlated with an equal degree of renal tubular reduction of tubular time of maximal concentration (T max ) of phosphate in both sexes, pointing to an additional factor in the creation of the bone disease in affected males. (medscape.com)
  • Bischoff-Ferrari et al reviewed evidence from studies that evaluated the thresholds of serum 25(OH)D levels and their relation to bone mineral density (BMD), lower-extremity function, dental health, and the risk of falls, fractures, and colorectal cancer. (medscape.com)
  • Cord blood levels of 25-hydroxyvitamin D [25(OH)D], calcium, and phosphorus were measured in 1491 neonates who were divided into three groups based on the duration of maternal vitamin D supplementation during pregnancy. (medscape.com)
  • [ 5 , 6 ] It is noteworthy that fetal and newborn concentrations of 25(OH)D depend on and correlate with maternal serum levels. (medscape.com)
  • Maternal and neonatal 25-hydroxyvitamin D concentrations and school-age lung function, asthma and allergy. (omicsdi.org)
  • Median age (25-75th percentile) was 61.5 (57.00-66.25) years, and mean bone mineral density (BMD) was 0.902 (0.800-1.042)g/cm 2 . (nature.com)
  • Median age of presentation was 15.1 months, with 25% presenting at less than 6 months of age. (bmj.com)
  • However, data obtained from various populations of community-living postmenopausal women with or without osteoporosis highlight a wide disparity of prevalence rates of 25(OH)D concentration ≤ 20 ng/mL depending on the considered geographical areas [ 7 , 8 ]. (hindawi.com)
  • Calcium absorption from diet correlates with 25(OH)D in the normal range. (preparedfoods.com)
  • By day 21, there appeared to be a dose dependent effect of EGME treatment on most of these variables including a significant increase in total calcium and ionic calcium while 1,25- dihydroxyvitamin-D3 was significantly decreased in groups treated at the 100mg/kg level. (cdc.gov)
  • The risk of developing both was significantly higher in persons who were 25(OH)D deficient or severely deficient. (atlaschiro.com)
  • We investigated the data according to quartiles of 25(OH)D concentrations. (e-apem.org)
  • Vitamin D supplementation could potentially improve total testosterone concentration, although more research is needed. (wikipedia.org)
  • The findings from China suggest that maternal vitamin D supplementation recommended by the IOM results in a slight but significantly higher fetal level of 25(OH)D and improves fetal growth. (medscape.com)
  • Conclusions: Myopia in young adulthood was most strongly associated with recent 25(OH)D concentrations, a marker of time spent outdoors. (edu.au)
  • D daily have a milk concentration of 50 to 80 IU/L (Sauberan 2019, við Streym 2016, Wagner 2006, Hollis 2004). (e-lactancia.org)
  • Published online 2019 Oct 25. (ppshp.fi)
  • 2019 Oct 25;11(11). (ppshp.fi)
  • Conclusion In T2DM patients, especially in female patients, serum 25(OH)VitD concentration is positively correlated to the blood viscosity. (shsmu.edu.cn)
  • 25-OHD correlated positively with birth weight while serum ferritin showed a negative correlation. (who.int)
  • The associations between vitamin D concentrations and various conditions and diseases have been assessed in a large and rapidly expanding literature. (bmj.com)
  • Individuals with higher serum vitamin D concentrations showed a reduced risk of Parkinson disease. (unboundmedicine.com)
  • these foods are closely monitored to establish targeted vitamin D concentrations. (cmaj.ca)
  • Vitamin D concentrations were obtained from the Canadian Nutrient File database (webprod3.hc-sc.gc.ca/cnf-fce/index-eng.jsp). (cmaj.ca)
  • Logistic regression was used to analyse the association between risk of myopia at age 20 years and age-specific 25(OH)D concentrations. (edu.au)
  • Linear mixed-effects models were used to analyse trajectory of 25(OH)D concentrations from 6 to 20 years. (edu.au)
  • Dans une analyse multivariée, le taux de 25-OHD sérique de la mère était positivement corrélé au poids à la naissance alors que dans le cas de la ferritine sérique, cette corrélation était négative. (who.int)
  • Low serum 25(OH)D level is associated with an increase of insulin resistance and metabolic syndrome in children and adolescents. (e-apem.org)
  • its magnitude can be calculated based on the actual serum 25-hydroxy-vitamin D level and body weight. (wikipedia.org)
  • A multiple regression analysis using the 25(OH)D cutoff value of 17 ng/mL instead of the generally admitted level of 20 ng/mL was performed to increase statistical power. (hindawi.com)
  • Serum 25-hydroxyvitamin D level was determined from frozen samples stored at baseline. (unboundmedicine.com)
  • thus, the total serum 25(OH)D level is currently considered the best indicator of vitamin D supply to the body from cutaneous synthesis and nutritional intake. (medscape.com)
  • The reference range of the total 25(OH)D level is 20-100 ng/mL. (medscape.com)
  • Purpose: To investigate the relationship between time spent outdoors, at particular ages in childhood and adolescence, and myopia status in young adulthood using serum 25-hydroxyvitamin D [25(OH)D] concentration as a biomarker of time spent outdoors. (edu.au)
  • After adjustment for gestational age at maternal iron status measurement and sociodemographic or lifestyle-related confounders, a higher maternal transferrin concentration was associated with a higher risk of physician-diagnosed inhalant allergy (odds ratio [95% confidence interval]: 1.13 [1.01 to1.26]), but not with lung function, asthma, or inhalant allergic sensitization. (omicsdi.org)
  • Measurement of serum 25-hydroxyvitamin D (25[OH]D) is the best test to determine vitamin D status. (medscape.com)
  • If the 25(OH)D concentration remains persistently low despite several attempts at correction with oral vitamin D, a trial of ultraviolet B light therapy (ie, by tanning lamps) may be considered to improve vitamin D status. (medscape.com)
  • It has become increasingly common for health enthusiasts and now even typical patients in the doctor's office to have a lab estimate their vitamin D status by measuring serum 25-hydroxyvitamin D, abbreviated 25(OH)D, and use vitamin D supplements to bring this value into the "sufficient" range. (westonaprice.org)
  • 25-hydroxyvitamin D is a metabolite of vitamin D that is present in food, is the predominant form of circulating vitamin D, and is the form that healthcare professionals measure to determine an individual's vitamin D status. (creighton.edu)
  • 25-hydroxyvitamin D3 is approximately three times as effective vitamin D3 in optimizing vitamin D status, and can do so much more rapidly. (creighton.edu)
  • At present, 25-hydroxyvitamin D3 is not available as a dietary supplement in the United States.If it were available, 25-hydroxyvitamin D3 could more rapidly and effectively optimize vitamin D status and support immune function. (creighton.edu)
  • In a study of more than 190,000 Americans, researchers found that reduced 25(OH)D status was strongly associated with increased risk of a positive COVID-19 PCR test. (dsm.com)
  • The first procedure involves an extraction of 25-OH-D and other hydroxylated metabolites from serum with acetonitrile. (cdc.gov)
  • The RIA method is based on an antibody with specificity to 25-OH-D. The sample, antibody, and tracer are incubated for 90 min at 20-25 °C. Phase separation is accomplished after a 20-minute incubation at 20-25 °C with a second antibody-precipitating complex. (cdc.gov)
  • [ 10 ] In general, these assays depend on an antibody that recognizes 25(OH)D2 and 25(OH)D3 in equimolar proportions and the competitive displacement of tracer 25(OH)D (25(OH)D that has been tagged with a radioactive isotope such as 125-I or a chemiluminescent ligand) by acetonitrile extracted samples. (medscape.com)
  • BMI and waist circumference were lower in the high 25(OH)D group. (e-apem.org)
  • A random-effect meta-analysis was done first, to calculate the summary relative risk (RR) and 95% confidence intervals (CIs) comparing the higher concentration with the lower concentration of 25[OH]D. A dose-response meta-analysis using random-effects model was then carried out to evaluate the nonlinearity and calculate the summary RR caused per 10 ng/mL increment. (dovepress.com)
  • We investigated associations between circulating 25-hydroxyvitamin D (25(OH)D) and risk of colorectal, breast, and prostate cancers, including subtypes. (unboundmedicine.com)
  • Vitamin D supplements are prescribed to correct low circulating concentrations of 25-hydroxyvitamin D. In CKD, vitamin D metabolism is complicated by decreased conversion of 25-hydroxyvitamin D to 1,25-dihydroxyvitamin D by CYP27B1 and possibly decreased conversion of 25-hydroxyvitamin D to 24,25-dihydroxyvitamin D by CYP24A1. (omicsdi.org)
  • We carried out a dose-response meta-analysis to quantitatively examine the association of circulating 25-hydroxyvitamin D (25[OH]D) concentration with prostate cancer. (dovepress.com)
  • Only prospective studies examining the associations of circulating 25[OH]D concentration with prostate cancer were eligible for the meta-analysis. (dovepress.com)
  • Dose-response meta-analysis showed that the summary RR caused per 10 ng/mL increment in circulating 25[OH]D concentration was 1.04 (95% CI 1.02-1.06). (dovepress.com)
  • 17 Meta-analyses of epidemiological studies have suggested that higher circulating 25-hydroxyvitamin D (25[OH]D) concentration is correlated with decreased risks of several common cancers, such as colorectal cancer and bladder cancer. (dovepress.com)
  • 18 , 19 Considering the preventive effect of vitamin D against cancer, many researchers also studied the association of circulating 25[OH]D concentration with prostate cancer. (dovepress.com)
  • Likewise, the circulating 25-hydroxyvitamin D concentrations of early humans were surely far higher than what is now regarded as normal. (westonaprice.org)
  • Circulating FGF-23 concentrations have been shown to be 5 times higher in XLH patients, resulting in significant phosphaturia. (medscape.com)
  • 12) reported a negative correlation between BMI and serum 25-hydroxy-vitamin D [25(OH) D] concentration, whereas Baradaran et al. (e-apem.org)
  • Objective To explore the correlation between serum 25-hydroxy vitamin D [25(OH)VitD] concentration and blood viscosity in type 2 diabetic (T2DM) patients. (shsmu.edu.cn)
  • The correlation between serum 25(OH)VitD concentration and blood viscosity at different shear rates was analyzed and a gender-stratified analysis was performed. (shsmu.edu.cn)
  • Maternal venous blood samples in mid-gestation and umbilical cord blood samples at birth were used to determine 25-hydroxyvitamin D concentrations. (omicsdi.org)
  • These significant differences on cord blood concentrations of 25(OH)D occurred regardless of the season of birth. (medscape.com)
  • Following synthesis in the skin or dietary intake, both forms of vitamin D are transported to the liver, and are hydroxylated to form 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2, respectively. (creighton.edu)
  • Our results suggest that maternal 25-hydroxyvitamin D concentrations in mid-gestation may influence lung development. (omicsdi.org)
  • A secondary analysis in which serum 25(OH)D concentrations were analyzed as a continuous variable provided a similar pattern of results, as did other analyses that adjusted for diabetes, hypertension, and ethnicity (for ethnicity, the results were somewhat altered, but the overall pattern didn't change). (atlaschiro.com)
  • Methods Two hundred and thirteen T2DM patients were enrolled and the serum 25(OH)VitD concentration and whole blood viscosity at different shear rates (1/s, 5/s, 30/s, and 200/s) were measured with enzyme-linked immunosorbent assay and electronic blood rheology analyzer. (shsmu.edu.cn)
  • 25-hydroxyvitamin D concentrations were available for 116 patients included in prospective trials in our clinic. (karger.com)
  • Finally, XLH patients demonstrate a normal or low serum concentration of 1,25-dihydroxyvitamin D3, suggestive of inadequate formation of this vitamin D metabolite. (medscape.com)
  • Even the serum concentration of 1,25 dihydroxyvitamin D is inappropriately normal or low in XLH patients. (medscape.com)
  • No nonlinear relationship was found between 25[OH]D concentration and risk of prostate cancer ( P =0.654). (dovepress.com)
  • Estimates of the relationship between serum vitamin D concentration and Parkinson disease incidence were calculated using the Cox model. (unboundmedicine.com)
  • We conducted linear regressions analyses (adjusted for sex, waist circumference, physical activity, hormone use, and season) to assess the relationship between 25-hydroxyvitamin D and biomarkers of dysglycemia, dyslipidemia, and inflammation in the study population. (cdc.gov)
  • However, the relationship between 25(OH)D and individual biomarkers of cardiometabolic disease has not been explored in the Canadian population, and whether it differs by sex is unknown. (cdc.gov)
  • 25-hydroxyvitamin D3 is also found in certain foods, particularly animal products such as meat, liver, and eggs. (creighton.edu)
  • Furthermore, autoimmunity and some infectious agents may also cause disease because of insufficient 25(OH)D [ 11 ]. (biomedcentral.com)
  • There were no associations between 25(OH)D at younger ages and myopia. (edu.au)
  • We examined the associations of 25-hydroxyvitamin D concentrations in mid-gestation and at birth with lung function, asthma, inhalant allergic sensitization and inhalant allergy at school-age. (omicsdi.org)
  • After additional adjustment for child's 25-hydroxyvitamin D concentrations at the age of 6 years, only the associations of 25-hydroxyvitamin D concentrations in mid-gestation with FEV 1 /FVC and FEF 75 remained. (omicsdi.org)
  • We did not find consistent associations of 25-hydroxyvitamin D concentrations at birth with respiratory or allergy outcomes. (omicsdi.org)
  • Furthermore, higher 25-hydroxyvitamin D concentrations in mid-gestation were associated with an increased risk of inhalant allergy (Odds Ratio [95% CI] 1.07 [1.02, 1.12]), but not with inhalant allergic sensitization. (omicsdi.org)
  • Higher 25[OH]D concentration was significantly correlated with elevated risk of prostate cancer (RR =1.15, 95% CI 1.06-1.24). (dovepress.com)
  • Systolic blood pressure and diastolic blood pressure with adjustment for sex and age differed significantly between the serum 25(OH)D groups and exhibited negative trend as 25(OH)D concentrations increased. (e-apem.org)
  • Clinical indexes such as blood viscosity and 25(OH)VitD should be comprehensively evaluated during the diagnosis and treatment of diabetes mellitus. (shsmu.edu.cn)
  • A blood sample was collected to measure 25-hydroxyvitamin D (25(OH)D) concentrations. (hindawi.com)
  • Fasting blood samples were obtained from the respondents to measure their serum 25-hydroxyvitamin D [25(OH)D] concentration. (mendeley.com)
  • Procedures -After an acclimation period, rabbits were anesthetized with isoflurane, and an initial blood sample was collected for determination of serum 25-hydroxyvitamin D concentration. (avma.org)
  • On day 14, another blood sample was collected from anesthetized rabbits for determination of serum 25-hydroxyvitamin D concentration. (avma.org)
  • Our objectives were to examine the association between 25(OH)D and traditional and novel biomarkers of cardiometabolic disease and to describe the extent of the month-to-month fluctuations of 25(OH)D in a representative sample of the general Canadian population. (cdc.gov)
  • Individuals who were myopic at 20 years had a 25(OH)D concentration trajectory that declined, relative to non-myopic peers, with increasing age. (edu.au)
  • Differences in 25(OH)D trajectory between individuals with and without myopia were greater among non-Caucasians compared to Caucasians. (edu.au)
  • Correction of seasonal variation of 25-hydroxycalciferol with U.V. radiation dose. (cdc.gov)
  • We observed no consistent association of maternal ferritin concentrations or transferrin saturation with child's respiratory or allergy outcomes. (omicsdi.org)
  • The Genetic Predisposition Score of Seven Obesity-Related Single Nucleotide Polymorphisms Is Associated with Better Metabolic Outcomes after Roux-en-Y Gastric Bypass. (cdc.gov)
  • Title : A Candidate Reference Measurement Procedure for Quantifying Serum Concentrations of 25-Hydroxyvitamin D3 and 25-Hydroxyvitamin D2 Using Isotope-Dilution Liquid Chromatography-Tandem Mass Spectrometry Personal Author(s) : Mineva, Ekaterina M.;Schleicher, Rosemary L.;Chaudhary-Webb, Madhulika;Maw, Khin L.;Botelho, Julianne C.;Vesper, Hubert W.;Pfeiffer, Christine M. (cdc.gov)
  • In this series, I will argue that we should emphasize serum 25(OH)D much less and emphasize the nutrient density and nutrient balance of the overall diet and lifestyle much more. (westonaprice.org)
  • 25-hydroxyvitamin D3 has a long history of safe consumption in foods. (creighton.edu)
  • D (25-OHD) concentrations were low in mothers and infants. (who.int)