To investigate the protective effects of SHED on concanavalin A (ConA)-induced hepatitis in mice , and to elucidate the associated regulatory mechanisms. (bvsalud.org)
Profound increases in indicators of cell death were observed in both Nrf2 wild-type (Nrf2-WT) mice and Nrf2-disrupted (Nrf2-KO) mice 24 h following intravenous injection of concanavalin A (12.5 mg/kg, ConA), a model for T cell-mediated acute inflammatory liver injury. (nih.gov)
The first example, developed in 1979, was based on a glucose-binding plant protein called concanavalin A (ConA). (chemistryworld.com)
Receptors3
Concanavalin A interacts with diverse receptors containing mannosecarbohydrates, notably rhodopsin, blood group markers, insulin-receptor the Immunoglobulins and the carcino-embryonary antigen (CEA). (wikipedia.org)
It was postulated that a cytoskeletal defect might underlie these abnormalities, and a cytoskeleton-dependent function, the surface distribution and mobility of concanavalin-A receptors, was studied on neutrophils from Schwachman's syndrome patients. (nih.gov)
Receptors for concanavalin A cluster at the front of polarized neutrophils. (nih.gov)
Lectin2
Texas Red is a red-fluorescent dye and when bound to Concanavalin A (Jackbean) Lectin (Con A) can show the binding pattern of this lectin in cellular imaging applications. (glycomatrix.com)
7. Interactions of concanavalin A with glycoproteins: formation of homogeneous glycoprotein-lectin cross-linked complexes in mixed precipitation systems. (nih.gov)
Lectins1
Whereas the exoplasmic face of plasma membrane is preferentially labeled by both lectins, the endoplasmic reticulum and nuclear envelope are strongly and uniformly labeled by concanavalin A but not by wheat-germ agglutinin. (rupress.org)
Phytohemagglutinin2
Further significant increases in mitogenic responses to phytohemagglutinin and concanavalin A were observed. (karger.com)
At recapture, blood was sampled for determination of plasma levels of PCBs and organochlorine pesticides (OCPs) and lymphocyte proliferation after in vitro stimulation with specific mitogens--phytohemagglutinin (PHA), pokeweed mitogen (PWM), concanavalin A (Con A), lipopolysaccharide (LPS), and purified protein derivative of Mycobacterium avium subsp. (nih.gov)
Autoimmune hepatitis2
Stem cells from human exfoliated deciduous teeth ameliorate concanavalin A-induced autoimmune hepatitis by protecting hepatocytes from apoptosis. (bvsalud.org)
Deletion of the C6orf120 gene with unknown function ameliorates autoimmune hepatitis induced by concanavalin A. Zhang MK, et al . (nih.gov)
Receptor2
Roy Chowdhury Alteration of surface receptor of Ehrlich tumour cells by concanavalin A (Con A), shortwave UV and UV plus Con A have been studied. (karger.com)
Transmembrane glycoproteins, glycophorin and the Concanavalin A receptor, were assembled into large multilamellar liposomes. (uwo.ca)
Magnetic relaxation dispersion3
Solvent proton magnetic relaxation dispersion in solutions of concanavalin A. (elsevierpure.com)
Solvent proton magnetic relaxation dispersion in solutions of concanavalin A. Proceedings of the National Academy of Sciences of the United States of America , 70 (2), 475-479. (elsevierpure.com)
Koenig, SH, Brown, RD & Brewer, CF 1973, ' Solvent proton magnetic relaxation dispersion in solutions of concanavalin A. ', Proceedings of the National Academy of Sciences of the United States of America , vol. 70, no. 2, pp. 475-479. (elsevierpure.com)
Succinyl1
1. Differences in the binding affinities of dimeric concanavalin A (including acetyl and succinyl derivatives) and tetrameric concanavalin A with large oligomannose-type glycopeptides. (nih.gov)
The time dependence of wheat germ agglutinin and Concanavalin A binding to two integral membrane glycoproteins has been examined in lipid bilayers. (uwo.ca)
Mice1
The present study was designed to investigate the potential benefits of vitamin C (VC) in treating immunological liver injury induced by Concanavalin A (Con A, 20 mg kg −1 ) in mice. (rsc.org)
Affinity1
Residual cross-reactive molecules were eliminated from Gp25 by affinity purification on Concanavalin A (Con A) columns. (ajtmh.org)
Agglutinin3
Freeze-fracture cytochemistry: localization of wheat-germ agglutinin and concanavalin A binding sites on freeze-fractured pancreatic cells. (rupress.org)
The combined application of thin-section and critical-point-drying "fracture-label" is used to determine the pattern of distribution and partition of wheat-germ agglutinin and concanavalin A binding sites on the membrane faces of freeze-fractured exocrine and endocrine rat pancreatic cells. (rupress.org)
A quantitative precipitation study of concanavalin A with the soybean agglutinin. (nih.gov)
Beads1
Cells were collected and incubated with Concanavalin A-coated beads. (nih.gov)
Purification1
Among the purification procedures employed will be Sephadex gel, ion exchange, concanavalin- A, electrophoresis, and high pressure liquid chromatography. (nih.gov)
Interactions3
2. Interactions of concanavalin A with asparagine-linked glycopeptides. (nih.gov)
4. Interactions of concanavalin A with asparagine-linked glycopeptides: formation of homogeneous cross-linked lattices in mixed precipitation systems. (nih.gov)
10. Interactions of concanavalin A with a trimannosyl oligosaccharide fragment of complex and high mannose type glycopeptides. (nih.gov)
Carbohydrates1
12. Studies of the binding specificity of concanavalin A. Nature of the extended binding site for asparagine-linked carbohydrates. (nih.gov)
Found1
Since in a part of the BPH we encounter elevations of PSA similar to the levels found in neoplasms, the degree of concanavalin A binding can provide an additional means in differentiating between benign and malignant lesions. (karger.com)
Model1
The concanavalin A (Con A)-induced hepatitis model has been widely used to study immune system-mediated liver injury. (medscape.com)