Computational models structural. Medical search. Frequent questions

Analytical methods for heat transfer are combined with mechanical models to calculate structural behaviour from single elements up to complete frames under real fire and ISO Standard furnace heating conditions. (iso.org)
Generative design, machine learning methods and Building Information Modelling (BIM) help to optimize the structural design. (uis.no)
Such automation facilitates the use and implementation of goal-oriented design methods that integrate energy performance with other types of building performance models. (researchgate.net)
Activities at EMBL Grenoble focus on integrated structural biology research, and on developing state-of-the art instrumentation, methods and services. (embl.org)
My research is focused on using computational methods to understand brain function and in the case of disease, brain dysfunction. (ncl.ac.uk)
I use methods from mathematical modelling, dynamical systems and graph theory to investigate complex brain network dynamics. (ncl.ac.uk)
The next wave of exciting new structures will come from so-called integrative/hybrid methods, which typically combine cryo-EM or -ET data with data from chemical cross-linking, fluorescence resonance energy transfer, and homology models to produce multi-scale structures of even larger biomolecular machines. (iscb.org)
Toxicology is one of the sciences that have slowly but surely embraced technology and new methods, focusing on high throughput and high content screenings, omics technologies, and mathematical modeling. (brill.com)
Structural Integrity and Durability of Advanced Composites: Innovative Modelling Methods and Intelligent Design presents scientific and technological research from leading composite materials scientists and engineers that showcase the fundamental issues and practical problems that affect the development and exploitation of large composite structures. (skillsoft.com)
Computational Methods in Social Sciences, 4 (1),13-21. (bvsalud.org)
The Master Programme in Applied Computational Science with specialisation in Geology will give you detailed knowledge about the underlying methods with respect to geology. (lu.se)
The parts of the education with non-mandatory courses include courses such as ecosystem modelling, Bayesian methods or introduction to artificial neural networks and deep learning. (lu.se)
A secondary goal that should be sought by a bioinformatics facility is to make algorithms and analysis methods accessible for non-computational biologists. (lu.se)

The calculated stress in the production casing was in a good agreement between Casinteg and Ansys models, while the computational time of Casinteg simulations was within minutes. (sintef.no)
Analysis of virulence related gene expression and computational simulations of pivotal proteins involved in pathogenesis demonstrate that myricetin downregulates the saeR global regulator and interacts with sortase A and α-hemolysin. (nature.com)
With the increase in the availability of high-quality observations and simulations, learning nudging from these increments to correct model errors has become an active research area. (arxiv.org)
Since the train-track complicated when it comes to dynamics, geometry, and material behaviour, it is necessary to make simplifications to be able to build the model and run the simulations in a reasonable time. (hindawi.com)

The Basel Computational Biology Conference (stylized as [BC]2) is a scientific meeting on the subjects of bioinformatics and computational biology. (wikipedia.org)
2013 "Genetic Variation + Human Health" 2012 "ECCB'12, 11th European Conference on Computational Biology" in association with the 10th Basel Computational Biology conference. (wikipedia.org)
The four institutes join forces in the Partnership for Structural Biology (PSB), which provides a uniquely comprehensive range of state-of-the-art structural biology platforms for sample production, sample characterisation and structure determination for both in house research and external users. (embl.org)
MBL Grenoble's researchers focus mainly on RNA biology and infection biology, in particular on the structural molecular biology of protein-RNA complexes involved in cellular gene expression and host-pathogen interactions. (embl.org)
Through the Joint Structural Biology Group (JSBG), EMBL staff collaborate with the ESRF in building and operating state-of-the-art X-ray beamlines, developing associated instrumentation and techniques, and providing expert help to visitors. (embl.org)
With specialist research groups and teams in both scientific areas research at EMBL Grenoble focuses on structural biology and molecular cell biology. (embl.org)
In addition, a number of technology-focused instrumentation teams provide an invaluable resource of technical know-how and support to aid the scientific community in the structural biology realm. (embl.org)
I trained in computer science and software engineering before doing a masters degree in computational molecular biology in Manchester. (ncl.ac.uk)
I am Associate Editor at PLoS Computational Biology. (ncl.ac.uk)
The Special Session will highlight examples of the exciting work going in in these two frontier areas of structural biology from four distinguished speakers, with reference to the manifold challenges and opportunities for the bioinformatics community. (iscb.org)
The term systems toxicology is derived from systems biology and could be defined as the study of biological systems, using omics technologies, with a focus on the mechanisms underlying complex biological processes, their interactions and perturbations in response to a toxin combined with mathematical data integration and modeling. (brill.com)
The main purpose of a bioinformatics platform within SWEGENE should be to provide com- putational facilities and logistical support [databases & infrastructure] for scientists whose primary research in biology and medicine benefit from computational approaches. (lu.se)
The hopes in these documents are that a bioinformatics effort should cover a large part of the computational biology area, with islands of specific problem domains and very little discussion on how to coordinate a computational biology effort. (lu.se)
The first 18 months into the SWEGENE project, the fourth main effort within SWEGENE, bioinformatics, has not produced a proposal on how to meet the needs of the current bio- logical problem domain, or how they should advance into the near, and long term, future research areas within computational biology. (lu.se)

My research interests are in Computational Protein Modeling and Structural Bioinformatics. (wisc.edu)
The purpose of a bioinformatics platform within SWEGENE is to provide computational facilities and logistical support [databases, algorithms & infrastructure] for problem oriented scientists in an optimal way. (lu.se)

IIE has excellent laboratory and computing facilities, including the latest facilities and instrumentation for experimental and computational research in structures, granular solids, fire safety engineering, non-destructive testing and environmental engineering. (ed.ac.uk)
Although considerable progress has been made in using experimental and computational techniques to determine start and final structural states, we have a limited understanding of what happens in between. (lu.se)

Basic theoretical and computational modeling of replicating systems. (uu.se)
Very recently, (DFT)(B3LYP) calculations on a cluster model showed very small a combined experimental and theoretical study by Cox et al. (lu.se)

Experimental characterization of structural and functional properties of biomolecules. (uu.se)

Given a structural motif of interest, such as a functional site, MA searches a target protein structure for a match: the set of atoms with the greatest geometric and chemical similarity. (nih.gov)
Walker S., Ullman O., Stultz CM. Using Intramolecular Disulfide Bonds in Tau Protein to Deduce Structural Features of Aggregation-resistant Conformations. (mit.edu)
eng] The study of the 3D structural details of protein-protein and protein-DNA interactions is essential to understand biomolecular functions at the molecular level. (tesisenred.net)
In this thesis project you wil work on characterizing a synthetic variant of a capsid protein from a natural virus that has been designed using computational structural modeling. (lu.se)

The comparison of structural subsites in proteins is increasingly relevant to the prediction of their biological function. (nih.gov)
Huang A., Stultz CM. Modeling Intrinsically Disordered Proteins with Bayesian Statistics. (mit.edu)
Recent highlights include: the structure and function of long non-coding RNAs , the structure of the integrator complex , the determination of the mechanism of action of secreted Legionella effector proteins , and the structural and mechanistic analysis of the transcription/replication machines of influenza virus and lassa virus . (embl.org)
A general property of disordered proteins is their structural expansion that results in a high macromolecular flexibility. (lu.se)

3D Genomics: Computational approaches for analyzing the role of three-dimensional chromatin organization in gene regulation. (iscb.org)

The method applies Bayesian probabilistic model to analyze scattering data from mixtures of oligomeric species, allows for a modeling large structural ensembles, can be used to assess uncertainty of all parameters and minimizes over-fitting. (lu.se)

Broadly speaking, two modeling approaches for the concepts and their relationship exist. (r-project.org)
Our chapter introduces some of the key concepts of epilepsy from a clinical perspective, before describing some of the classical approaches to modelling brain activity across multiple levels of description. (springer.com)

Despite the apparent limitations of structural color, the researchers say these can be overcome by using other kind of nanostructures, such as network structures or multi-layered hierarchical structures, although these systems are not fully understood yet. (phys.org)
Get the latest information on how to extend the design life of structures and accurately predict both the fundamental material behavior and structural response under a wide range of load conditions. (astm.org)
The current research and development activities in our group can be divided into concrete structures and technology, wind engineering and extreme loads, fatigue and structural integrity. (uis.no)
We work on a wide range of topics on concrete structures in onshore and offshore including cracking behaviour of reinforced concrete structures, condition assessment and control of structures, environmentally friendly building materials, optimization and digitalization of structural engineering applications and low carbon concrete. (uis.no)
For the intermediate S2 and S3 structures there is also which ligands are water and which are hydroxides, agree, along nearly complete agreement between quantum chemical modeling with which manganese are Mn(III) and which are Mn(IV) at that and experiments. (lu.se)
To overcome this problem we develop a method that combines a computational structural modeling (which delivers atomic-resolution structures) with experimental data (which provides information about the population of different states). (lu.se)

He is also Professor in the Institute for Computational and Mathematical Engineering, and Director of the Stanford-King Abdulaziz City for Science and Technology Center of Excellence for Aeronautics and Astronautics. (stanford.edu)
When choosing tFhe appropriate mathematical model, element type and degree of discretization are important to obtain accurate as well as time and cost effective solutions. (bvsalud.org)

He has been an AGARD lecturer on aeroelasticity and computational mechanics at several distinguished European institutions, and a plenary or keynote speaker at numerous national and international scientific meetings. (stanford.edu)

Earth system models suffer from various structural and parametric errors in their representation of nonlinear, multi-scale processes, leading to uncertainties in their long-term projections. (arxiv.org)
Using two-layer quasi-geostrophic turbulence as the test case, MEDIDA is shown to successfully discover various linear and nonlinear structural/parametric errors when full observations are available. (arxiv.org)
A unifying explanation of primary generalized seizures through nonlinear brain modeling and bifurcation analysis. (springer.com)

I completed my PhD in 2013, studying dynamical systems theory and computational modelling in epilepsy with Gerold Baier . (ncl.ac.uk)
In this chapter we present a review of computational models for studying the dynamic mechanisms that describe the function of the human brain, with a specific focus on epilepsy. (springer.com)
We then focus on how these models have been used to explain and predict experimental and clinical phenomena within the field of epilepsy research. (springer.com)
Here we focus on techniques that seek to integrate computational modelling with experimental and clinical measures, as we believe this "systems approach" to epilepsy research is from where the most significant new advances, particularly with regards model validation, will occur. (springer.com)
Benjamin O, Fitzgerald THB, Ashwin P, Tsaneva-Atanasova K, Chowdhury F, Richardson MP, Terry JR. A phenomenological model of seizure initiation suggests network structure may explain seizure frequency in idiopathic generalised epilepsy. (springer.com)

Introduction: The finite element method (FEM) involves a series of computational procedures to calculate the stress in each element, which performs a model solution. (bvsalud.org)

The inherent complexity of biological systems is a challenge that is expected to be overcome by computational modeling of biological systems. (brill.com)

Our results show that the hierarchy of functional importance within structural motifs speeds up the search within targets, and points to a new method to score their statistical significance. (nih.gov)
A vital first step in the design of advanced materials is understanding and characterising their structure on a range of lengthscales, and so researchers in the functional materials theme are often actively involved themselves, or through close collaboration, with work in the structural chemistry and chemical dynamics theme . (st-andrews.ac.uk)
The HEM design concept, shifts the focus away from the corners of phase diagrams toward their centers, allows compositions beyond the scope of traditional materials, offering unprecedented properties, challenges and opportunities for a wide range of structural and functional applications. (mrs.org)
I use functional data such as EEG, MEG and fMRI in addition to structural data derived from MRI and diffusion MRI. (ncl.ac.uk)

The goal is to combine current parametric modeling, digital fabrication, and computer graphics techniques to automatically generate the geometric input of an energy model from any digital 3D model of a building. (researchgate.net)
The Likert scale analysis using parametric based Structural Equation Modeling (SEM). (bvsalud.org)

The basic model was developed in the Laboratory for Image and Video Engineering (LIVE) at The University of Texas at Austin and further developed jointly with the Laboratory for Computational Vision (LCV) at New York University . (wikipedia.org)
Further variants of the model have been developed in the Image and Visual Computing Laboratory at University of Waterloo and have been commercially marketed. (wikipedia.org)

Applied computational science can be divided into several components: mathematics, modelling, statistics, and programming. (lu.se)
In the first year of the specialisation Geology, you study courses in mathematics, statistics and programming which will give you knowledge to conduct projects in computational science. (lu.se)

Cannabinoid type-1 receptor blockade restores neurological phenotypes in two models for Down syndrome. (upf.edu)
Carcolé M, Kummer S, Gonçalves L, Zamanillo D, Merlos M, Dickenson AH, Fernández-Pastor B, Cabañero D, Maldonado R. Sigma-1 receptor modulates neuroinflammation associated with mechanical hypersensitivity and opioid tolerance in a mouse model of osteoarthritis pain. (upf.edu)
SCR-6852, an oral and highly brain-penetrating estrogen receptor degrader (SERD), effectively shrinks tumors both in intracranial and subcutaneous ER + breast cancer models. (medscape.com)

Fundamental considerations of solid pyrolysis and complex thermal degradation process will be fused into a high-fidelity computational fluid dynamics framework based on direct numerical simulation (DNS) yielding reliable and robust predicted the result for fire safety design. (edu.au)
Furthermore, substructures that are complex to model numerically can be tested physically, allowing for real measurements of the output quantities of interest (QoI). (frontiersin.org)
This work presents a new methodology to automate the derivation of Building Energy Models (BEMs) from complex 3D Computer-Aided Design (CAD) geometry. (researchgate.net)
MBS tool dedicated for train-track analysis has a wheel-rail contact module that is able to model complex wheel-rail kinematic behaviour and the corresponding creep forces. (hindawi.com)
You will learn how to study complex processes in natural sciences and how Computational Science can contribute to knowledge evolution in society. (lu.se)
By enabling both time resolution and structural detail Time-Resolved Small Angle X-ray/Neutron Scattering (TR-SAXS/TR-SANS) is uniquely suited to interrogate complex self-assembly reactions and to provide a molecular understanding of self-assembly pathways. (lu.se)

We investigate how to integrate different digital tools to optimize the structural design effectively and efficiently. (uis.no)
We integrate the computational and the experimental studies. (uis.no)
Lapique's introduction of the integrate-and-fire model neuron (1907). (springer.com)

Here, we developed a computational approach for detecting PPIs trained and tested on known PPIs of Arabidopsis thaliana and applied to three plants, Arabidopsis thaliana , Glycine max (soybean), and Zea mays (maize) to discover new PPIs on a genome-scale. (nature.com)
ISO/TR 12471:2004 reviews advances in computational analysis and indicates how these can be used with probabilistic analysis to provide a risk-based approach to structural fire engineering design. (iso.org)
Studying the association between longitudinal mammographic density measurements and breast cancer risk: a joint modelling approach. (medscape.com)

Recently we have shown that a coarse-grained model based on the primitive model, that has been used for modelling polyelectrolytes for over 30 years, works well for a range of IDPs where electrostatics governs the intra- and intermolecular interactions [1]. (lu.se)

Computer modeling and analysis of the Greens Creek Mine, Admiralty Island, AK. (cdc.gov)
This study was conducted at the Greens Creek Mine, which is typical of many VMS-type deposits throughout southeast Alaska , and served as a case history for computer modeling and structural analysis. (cdc.gov)
Here, we show the capabilities of Model Error Discovery with Interpretability and Data Assimilation (MEDIDA), a general, data-efficient framework that uses sparsity-promoting equation-discovery techniques to learn model errors from analysis increments. (arxiv.org)
These feature descriptors were used to build a 3D-QSAR model, which was validated using Cost analysis and Fischer's randomization test. (bvsalud.org)
Such a structural analysis allows the determination of stress resulting from external force, pressure, thermal change, and other factors. (bvsalud.org)

The reliability and efficiency of the constitutive models implemented in Casinteg were verified in comparison with Abaqus. (sintef.no)
Computational Techniques rs advanced computational and experimental techniques to develop constitutive models for composite and shape memory materials. (astm.org)

Structural equation modeling (SEM) has been used and developed for decades across various research fields such as (among others) psychology, sociology, and business research. (r-project.org)

The entirety of these measurement relations is captured by the measurement model which relates indicators to latent variables according to the researchers theory of how observables are related to the concepts in question. (r-project.org)
In addition to knowledge of theory of computational science, there will be an emphasis on obtaining knowledge about the practical tools that are used by professionals in the field and you will amongst several things train your skills in programming. (lu.se)
Lending further support to this theory, computational simulation of gradual inferior turbinate resection demonstrates a stepwise reduction in air-warming capacity. (medscape.com)

Albeit attractive, real-time hybrid simulation comes with numerous challenges, such as the inherent dynamics of the transfer system used, along with communication interrupts between numerical and physical substructures, that introduce time delays to the overall hybrid model altering the dynamic response of the system under consideration. (frontiersin.org)
During the test, the dynamic response of the physical substructure is measured and fed back to the numerical substructure, completing the unknown terms of the governing equations of motion of the hybrid model needed to compute the following command for the next time step of the simulation. (frontiersin.org)
The researchers, from the University of Cambridge, used a numerical experiment to determine the limits of matt structural color-a phenomenon which is responsible for some of the most intense colors in nature-and found that it extends only as far as blue and green in the visible spectrum. (phys.org)
The researchers, who are based in the lab of Dr. Silvia Vignolini, used numerical modeling to determine the limitations of creating saturated, pure and matt red structural color. (phys.org)
Dynamic track properties of a railway track are identified through numerical receptance test on a simple straight track model. (hindawi.com)

PEMer: a computational framework with simulation-based error models for inferring genomic structural variants from massive paired-end sequencing data. (gersteinlab.org)

The proposed single, streamlined workflow generates digital models that are suitable for both energy optimization and digital fabrication, thereby facilitating the integration of two parallel design procedures at the core of an architectural design process. (researchgate.net)

The analyses of the recorded ambient vibration data include identification of built-in structural dynamic properties, heavy vehicle tracking etc. (uis.no)

The train-turnout coupled dynamic interaction is compared to the dynamic interaction simulated from a widely accepted moving mass train-turnout model. (hindawi.com)
It is concluded that the train-turnout coupled model can provide a more realistic train-turnout dynamic interaction compared to the moving mass train-turnout model. (hindawi.com)

In addition to their intensity and resistance to fading, a matt paint which uses structural color would also be far more environmentally-friendly, as toxic dyes and pigments would not be needed," said first author Gianni Jacucci from Cambridge's Department of Chemistry. (phys.org)

The Training Centre expects to create knowledge on novel green and durable fire retardant materials, advanced fire models for urban and built environment, fire suppression technologies, and new flammability tests for compliance with fire safety regulatory standards. (edu.au)
ISO/TR 12471:2004 gives a review of the advances that have been made in measuring and understanding how structural materials respond to fire in terms of changes in their elevated temperature, and physical and mechanical characteristics, and to identify areas where further work is necessary to generate the data required. (iso.org)
Electronic Materials usses the application of the Weibull models used extensively for steel fracture to assess the interfacial fracture of electronic components. (astm.org)

Through this workflow, a single CAD model generates solutions that are energy efficient and feasibly fabricated using digital techniques. (researchgate.net)
This paper demonstrates the applications of coal bed reservoir engineering and modeling techniques for optimizing and controlling methane emissions in longwall and continuous miner sections. (cdc.gov)
So, the application of engineering knowledge in dentistry with the use of computational techniques has helped to understand oral biomechanics aspects. (bvsalud.org)

The proposed methodology facilitates the modeling of thermal zones with double-curved envelopes, which is a time-consuming task that typically requires a high level of expertise from the energy modeler. (researchgate.net)
In this paper, a train-turnout coupled model methodology using a MBS tool GENSYS is presented. (hindawi.com)

Second, in order to interpret matches, we further introduce a statistical method using nonparametric density estimation of the frequency distribution of structural matches. (nih.gov)

The position for have indicated relatively large structural changes in this transition, the slowly exchanging substrate agrees with the one suggested by with changes of distances sometimes larger than 0.3 Å and a change the DFT studies (4, 11-13), but there is still a minor possible of topology. (lu.se)

Although the workshop hosts papers that treat issues fundamental to the computational modeling and scientific understanding of narrative, this year we have a focus on narrative's cognitive, linguistic, or philosophical aspects. (wikicfp.com)
You will be exploring fundamental ideas in Computer Science, and the far-reaching impact of computational thinking on modern society. (sfu.ca)

EMBL Grenoble shares the European Photon and Neutron (EPN) science campus with the European Synchrotron Radiation Facility (ESRF), the Institut Laue-Langevin (ILL, Europe's high flux neutron source), and the French Institut de Biologie Structurale (IBS). (embl.org)

This can be attributed to mechanical engineering principles that are present in these specialties, favoring the use of finite element modeling. (bvsalud.org)

In this study a novel tool, Casinteg, was developed for structural analyses of geothermal wells. (sintef.no)
Casinteg's capability for structural analyses of full geothermal wells was preliminarily investigated, using IDDP-1 well as a case study. (sintef.no)
The MBS method is known to be efficient to study the train dynamics, but the tradeoff is the track model that has to be simplified. (hindawi.com)
With further technological developments, these human in vitro cellular models shall be highly useful in the screening of compounds for personalized medicine, allowing optimum therapy with minimum or no adverse effects, and in the study of adverse outcomes in different strata of population. (brill.com)

Anatomy41

Organisms6

Diseases3

Chemicals and Drugs10

Analytical, Diagnostic and Therapeutic Techniques and Equipment48

Psychiatry and Psychology42

Phenomena and Processes92

Disciplines and Occupations13

Anthropology, Education, Sociology and Social Phenomena1

Technology, Industry, Agriculture3

Information Science25

Health Care11

Methods13

Simulations4

Biology14

Bioinformatics2

Experimental and computational2

Theoretical2

Characterization1

Protein4

Proteins4

Genomics1

Bayesian1

Approaches2

Structures6

Mathematical2

Aeroelasticity1

Nonlinear3

Epilepsy5

Finite Elemen1

Biological Systems1

Functional4

Parametric2

Laboratory2

Mathematics2

Receptor3

Complex6

Integrate3

Approach3

Coarse-grained model1

Analysis5

Constitutive2

Research1

Theory3

Numerical5

Framework1

Optimization1

Vibration1

Interaction2

Chemistry1

Materials3

Techniques3

Methodology2

Estimation1

Large structural1

Fundamental2

Synchrotron1

Mechanical1

Study4