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  • organic compounds
  • The present invention relates to novel organic compounds which have great potential as useful medicaments and which may accordingly be developed and offered for treating the disorders of humans and animals. (google.com.au)
  • retinoids
  • This literature reports also that retinoic acid, retinoids, and related compounds have significant therapeutic potential in oncology and dermatology. (google.com.au)
  • These compounds and retinoids are said to be suitable for systemic and topical treatment of acne, psoriasis and precancerous conditions and for other dermatopathy which is accompanied by hyperkeratinization as well other pathologic and allergic dermatological disease. (google.com)
  • relatively
  • Under basic conditions, the active iodinating species are iodine(III) compounds in which any relatively acidic ligands on iodine (such as acetate) have been replaced by alkoxide. (wikipedia.org)
  • The reason for this could be that WIN35428 is relatively easier to displace from the DAT versus paroxetine from the SERT, because of the higher binding constant of the former compound. (wikipedia.org)
  • The main advantage of column chromatography is the relatively low cost and disposability of the stationary phase used in the process. (wikipedia.org)
  • Although some bisamidites were reported as thermally unstable compounds, 2-cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite, the amidite used for the preparation of commercial nucleoside phosphoramidites, is relatively stable. (wikipedia.org)
  • Nucleoside phosphoramidites are relatively stable compounds with a prolonged shelf-life when stored as powders under anhydrous conditions in the absence of air at temperatures below 4 °C. The amidites will withstand mild basic conditions. (wikipedia.org)
  • trifluoromethyl
  • Compounds with large electronegative groups such as trifluoromethyl can form supramolecular associations or aggregates or clusters in which these groups are separated from each other as much as possible with minimized electrostatic repulsions. (wikipedia.org)
  • widely
  • For example, one of the most widely used silica gel grades in the former technique is mesh 230 - 400 (40 - 63 µm), while the latter technique typically requires mesh 70 - 230 (63 - 200 µm) silica gel. (wikipedia.org)
  • CHEMISTRY
  • However, after great developments in synthetic organic chemistry, there are still few methodologies that allow the stereoselective construction of predetermined moieties in some classes of compounds. (scielo.br)
  • molecular
  • Tiekink, E. R. T.: Tert-butoxysilanols as model compounds for labile key intermediates of the sol-gel process: crystal and molecular structures of (t-BuO)3SiOH and HO[(t-BuO)2SiO]2H, Appl. (wikipedia.org)
  • Size-exclusion chromatography (SEC), also known as molecular sieve chromatography, is a chromatographic method in which molecules in solution are separated by their size, and in some cases molecular weight. (wikipedia.org)
  • The other advantage to this experimental method is that in certain cases, it is feasible to determine the approximate molecular weight of a compound. (wikipedia.org)
  • To determine approximate molecular weight, the elution volumes of compounds with their corresponding molecular weights are obtained and then a plot of "Kav" vs "log(Mw)" is made, where Kav = (Ve-Vo)/(Vt-Vo) and Mw is the molecular mass. (wikipedia.org)
  • reagents
  • Carbonyl oxidation with hypervalent iodine reagents involves the functionalization of the α position of carbonyl compounds through the intermediacy of a hypervalent iodine(III) enolate species. (wikipedia.org)
  • Silyl enol ethers undergo many of the same reactions as carbonyl compounds in the presence of iodine(III) reagents. (wikipedia.org)
  • interactions
  • Δ G m i x = Δ H m i x − T ⋅ Δ S m i x {\displaystyle \Delta G_{mix}=\Delta H_{mix}-T\cdot \Delta S_{mix}} Without interactions between the compounds there would be no enthalpy of mixing and the entropy of mixing would be ideal. (wikipedia.org)
  • form
  • Compounds such as biphenyl and naphthalene are reduced by the powder and form highly coloured radical anions. (wikipedia.org)
  • An aqueous solution of the acid or base is added, and the pH of the aqueous phase is adjusted to bring the compound of interest into its required form. (wikipedia.org)
  • wherein
  • 2. A compound according to claim 1, wherein R 1 represents isopropyl, cyclopropyl, or butyl. (google.com.au)
  • 7. Process as claimed in claim 2, wherein after all the reactions are complete, the conjugate obtained is purified, in order to remove the unreacted compound P 2 -S-S-X therefrom. (google.com.au)
  • Process
  • 1. Process for the preparation of a cytotoxic product having a covalent disulphide bond between a cytotoxic compound and an antibody, the process comprising forming a disulphide bridge between the A chain of ricin and the antibody, the antibody being an immunoglobulin or an immunoglobulin fragment and being specific for a given antigen carried by the cells which are to be destroyed. (google.com.au)
  • The specific pI of the target protein can be used to model the process around and the compound can then be purified from the rest of the mixture. (wikipedia.org)
  • The sol-gel process, which entails the conversion of, for example, Si(OEt)4 into hydrated SiO2, proceeds via silanol intermediates. (wikipedia.org)
  • method
  • The application discloses certain stilbene compounds, pharmaceutical compositions thereof, method of treating thereof, method of diagnosis therewith, and method for the preparation thereof. (google.com.au)
  • 7. Method for diagnosis to determine the type of leukemia which comprises the incubation of the blood of a patient with leukemia in vitro in the presence of a compound of claim 1, and the observation of morphological changes and/or of colony formation of the leukemia cell. (google.com.au)
  • hydrogen
  • The powder is mixed with additional (wet) silica gel which provides additional hydrogen. (wikipedia.org)
  • Potassium graphite Alkali Metals Plus Silica Gel: Powerful Reducing Agents and Convenient Hydrogen Sources James L. Dye, Kevin D. Cram, Stephanie A. Urbin, Mikhail Y. Redko, James E. Jackson, and Michael Lefenfeld J. Am. Chem. (wikipedia.org)
  • solution
  • Megaphone acetate was also isolated from the root of Endlicheria dysodantha, another plant of Laurel family, using chromatography of ethanolic solution. (wikipedia.org)
  • name
  • Hydrostatic instruments are marketed under the name centrifugal partition chromatography (CPC). (wikipedia.org)
  • Megaphone is a cytotoxic neolignan obtained from Aniba megaphylla, a flowering plant of Laurel family which gave the compound its name. (wikipedia.org)
  • useful
  • The compounds and compositions are useful for diagnosis of leukemia types, the treatment of dermatological disorders, and as differentiation-inducing agents for neoplastic cells. (google.com.au)
  • This can be a useful way to generate α,β-unsaturated carbonyl compounds in the absence of functional handles. (wikipedia.org)
  • DMACA is a dye that is particularly useful for localization of procyanidin compounds in plant histology. (wikipedia.org)
  • presence
  • In the presence of enolizable carbonyl compounds, they are able to accomplish oxidative functionalization of the α position. (wikipedia.org)
  • The most important feature of phosphoramidites is their ability to undergo the phosphoramidite coupling reaction that is, to react with nucleophilic groups in the presence of an acidic azole catalyst, 1H-tetrazole, 2-ethylthiotetrazole, 2-benzylthiotetrazole, 4,5-dicyanoimidazole, or a number of similar compounds. (wikipedia.org)
  • active
  • 9. A differentiation-inducing agent for neoplastic cells, especially leukemia cells, comprising as active ingredient one or more stilbene compounds of claim 1. (google.com.au)
  • main
  • Wind tunnel studies revealed that the addition of small amounts (0.3%) of Z9-14:Ald to the main pheromone blend of H. armigera increased the males' attraction, but at higher doses (1%, 10%) the same compound acted as an inhibitor. (frontiersin.org)
  • organic
  • However, it is often convenient to have the compound dissolved in the organic phase after the last step, so that the evaporation of the solvent yields the product. (wikipedia.org)
  • Treatment with aluminium gives triphenyl aluminium: 3 Ph2Hg + 2 Al → (AlPh3)2 + 3 Hg As indicated above, organomercury compounds react with halogens to give the corresponding organic halide. (wikipedia.org)
  • Meanwhile, group 1 metals such as lithium, sodium, and potassium, and their organic compounds (e.g. sodium naphthalene) serve as effective anionic initiators. (wikipedia.org)
  • reaction
  • The differences in these variations refer to the characteristics of the amoebocyte/endtoxin reaction (e.g. gel-clot produces a precipitate and colorimetric changes color). (wikipedia.org)
  • Organomercury compounds are generated by many methods, including the direct reaction of hydrocarbons and mercury(II) salts. (wikipedia.org)
  • heavy
  • Heavy metal poisoning Mercury poisoning Minamata disease Compounds of carbon with other elements in the periodic table: Hintermann, H. (2010). (wikipedia.org)