Chemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentTechnology, Industry, AgricultureNamed GroupsHealth Care
BenzethoniumCerebrospinal Fluid ProteinsQuaternary Ammonium CompoundsChloridesSoapsDeodorantsPersonnel, HospitalOff-Label UseHand DisinfectionHygieneHand Hygiene
ChloroxylenolBenzalkonium chloride and benzethoniumHighly effective antimicrobial activityAntimicrobialAmmonium chlorideBenzylTriclocarbanCationicCetylpyridiniumDisinfectantAntibacterialDetergentQuaternary compound12.0PreservativeSodium chlorideHyamineEthyl AlcoholSyntheticSurfactantsSoluble in waterAqueousHePCCutaneous2023PathogensChemicalsGrapefruitIngredientsBroad spectrumBacteriaAntisepticsVitroActivityProductsMixtureToxicSolutionsProductMethodsChemicalPowderSkin
Chloroxylenol1
Benzalkonium chloride and benzethonium2
  • Such synthetic compounds like benzalkonium chloride and benzethonium chloride are used in the cosmetics industry and are very toxic antimicrobial preservatives. (brainreference.com)
  • The oral dosage form of claim 1 wherein said surfactant(s) comprise one or more cationic surfactants selected from the group consisting of benzalkonium chloride and benzethonium chloride.4. (patenthub.cn)
Highly effective antimicrobial activity2
  • In addition to its highly effective antimicrobial activity, benzethonium chloride contains a positively charged nitrogen atom covalently bonded to four carbon atoms. (wikipedia.org)
  • Benzethonium Chloride: in addition to having highly effective antimicrobial activity, benzethonium chloride is positively charged. (zenmed.com)
Antimicrobial2
  • GSE features the best of both worlds: the quaternary compounds derived from grapefruit exhibit broad-spectrum antimicrobial activity, while evidencing none of the toxic side effects of chemically derived quaternaries. (naturalhealthgarden.ca)
  • Quaternary ammonium compounds (QACs) have been widely used as cationic surfactants for fabricating industrial products, such as antimicrobial soap, disinfectants, detergents, fabric softeners, preservatives, and pest control products since 1935 [ 1 ]. (eeer.org)
Ammonium chloride3
  • Quaternary ammonium compounds or cationic detergents are synthetic derivatives of ammonium chloride (Arena et al. (inchem.org)
  • Quaternary Ammonium Compounds (Quats) or commonly labeled Benzalkonium chloride, Benzethonium chloride, Alkyl dimethyl benzyl ammonium chlorides (C12-16) Alkyl dimethyl benzyl ammonium chloride (C14 60%, C16 30%, C12 5%, C18 5%), Alkyl dimethyl ethylbenzyl ammonium chloride (C12-14), Alkyl dimethyl ethylbenzyl ammonium chlorides (C12-18), Didecyldimethylammonium chloride and Dioctyldimethylammonium chloride. (healthyplanetproducts.net)
  • Among the BACs reported to date, benzyl dimethyl dodecyl ammonium chloride (BAC 12 ), benzyl dimethyl tetradecyl ammonium chloride (BAC 14 ), and benzyl dimethyl hexadecyl ammonium chloride (BAC 16 ) have been widely used because of their high bioavailability [ 4 ]. (eeer.org)
Benzyl2
  • A benzethonium is a quaternary ammonium cation, N-benzyl-N,N-dimethyl-2-{2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy}ethanaminium, whose chloride is an industrial disinfectant. (answers.com)
  • Dimethyl benzyl amine is a ionic compound? (answers.com)
Triclocarban1
  • It's still the most common compounds found in antibacterial soaps, along with triclocarban. (buffstore.co.uk)
Cationic2
  • Benzalkonium chloride is a quaternary ammonium antiseptic and disinfectant with actions and uses similar to those of other cationic surfactants. (vizagchemical.com)
  • Because of their strong cationic surface activity, quaternary compounds are used primarily as disinfectants, biocides, and detergents, but also as anti-electrostatics, and as phase transfer catalysts. (vizagchemical.com)
Cetylpyridinium2
  • Two excipients, cetylpyridinium chloride and thimerosal , are potentially capable of reaching levels in the body that could lead to unwanted effects. (chemistryworld.com)
  • Two substances reached levels that could have relevant effects, namely organomercury antibacterial thimerosal, often used in vaccines, and cetylpyridinium chloride, an antiseptic often used in mouthwash. (chemistryworld.com)
Disinfectant2
  • Benzethonium chloride is also used in the food industry as a hard surface disinfectant. (wikipedia.org)
  • Quats (quaternary ammonium compounds) are potent disinfectant chemicals commonly found in disinfectant wipes, sprays and other household cleaners that are designed to kill germs. (womensvoices.org)
Antibacterial2
  • Recently, MRSA has moved from its historic hospital setting with new cases being found in public settings and reaching younger, healthier people. A new study indicates that many antibacterial products have some value, but a product made with benzethonium chloride kills common types of non-hospital, or community associated, MRSA bacteria better than other compounds. (yourlawyer.com)
  • Although there's not a lot of data about the effectiveness of topical, antibacterial products in infection prevention, researchers know it takes large numbers of bacteria to produce an infection and antibacterial treatments can greatly reduce their number. Tec Laboratories, a company that sells the benzethonium chloride product, funded the research. (yourlawyer.com)
Detergent2
  • Aqueous solutions of benzalkonium chloride foam when shaken, have a low surface tension and possess detergent and emulsifying properties (Wade & Weller, 1994). (inchem.org)
  • This synthetic compound has an anti-infective, antiseptic and surfactant (detergent) properties. (pawpawdear.com)
Quaternary compound2
  • Nutribiotic's Maximum GSE Liquid Concentrate contains Citricidal, which is a natural quaternary compound synthesized from the seed and pulp of grapefruit that has been proven highly effective in numerous applications. (brainreference.com)
  • The B vitamin choline is also a quaternary compound, but is nontoxic and even essential for maintaining healthy neurological function and fat metabolism. (naturalhealthgarden.ca)
12.02
  • An ointment containing 6.0% HePC and 12.0% benzethonium chloride was prepared according to the British Pharmacopoeia and British Pharmaceutical Codex methods by fusion techniques. (who.int)
  • 12.0% benzethonium chloride was prepared epidemic. (who.int)
Preservative2
  • Benzalkonium Chloride (BKC) is widely used as an Anti-Static, Emulsifier & Preservative in the Coatings Industry (Paints, Wood Treatment, Electronics, etc. (vizagchemical.com)
  • Benzalkonium chloride, a common ophthalmic preservative, compromises rat corneal cold sensitive nerve activity. (jefferson.edu)
Sodium chloride1
  • Benzethonium chloride is also used to titrate the quantity of sodium dodecyl sulfate in a mixture of sodium dodecyl sulfate, sodium chloride and sodium sulfate, using dimidium bromide-sulphan blue as an indicator. (wikipedia.org)
Hyamine1
  • Benzethonium chloride, also known as hyamine is a synthetic quaternary ammonium salt. (wikipedia.org)
Ethyl Alcohol1
Synthetic1
  • GSE liquid concentrate is very effective against pathogens due to its natural quaternary compounds which are molecularly similar to the ones that belong to a family of synthetic quaternary ammonium. (brainreference.com)
Surfactants1
  • Surfactants are compounds that lower the surface tension of a liquid so it increases the contact between the liquid and another substance. (nobullbeauty.com)
Soluble in water2
Aqueous1
HePC2
  • ABSTRACT A placebo-controlled trial compared 6% hexadecyl-phosphorylcholine (HePC) and 12% benzethonium chloride ointment with placebo ointment for treatment of cutaneous leishmaniasis. (who.int)
  • Hexadecyl-phosphorylcholine (HePC), an alkylphosphorylcholine compound, is the most promising of the new class of anti-tumour agent. (who.int)
Cutaneous1
  • During the last 2 decades, many attempts have been made to develop effective new compounds for treating cutaneous leishmaniasis (CL) that would be economical, that could be applied topically to lesions and that would avoid the development of resistance. (who.int)
20231
  • The global urology devices market size is expected to grow from $34.60 billion in 2022 to $37.10 billion in 2023 at a compound annual growth rate (CAGR) of 7.2% . (thebusinessresearchcompany.com)
Pathogens1
  • Independent testing shows that benzethonium chloride is highly effective against such pathogens as methicillin-resistant Staphylococcus aureus, Salmonella, Escherichia coli, Clostridium difficile, hepatitis B virus, hepatitis C virus, herpes simplex virus (HSV), human immunodeficiency virus (HIV), respiratory syncytial virus (RSV), and norovirus. (wikipedia.org)
Chemicals1
  • Quaternary compounds, including the benzalkonium salts, constitute an economically important class of industrial chemicals that are widely distributed among a diverse array of products and users from an industrial to the household sector. (vizagchemical.com)
Grapefruit1
  • While Grapefruit Seed Extract is molecularly similar to these compounds, there are some profound differences in structure and function. (brainreference.com)
Ingredients2
  • A ruling on benzethonium chloride, along with two other similar ingredients, was deferred for a year to allow for more data collection. (wikipedia.org)
  • Quaternary ammonium compounds are the active ingredients in disinfectants and sanitizers for homes, farms, hospitals, offices and public transportation vehicles. (inchem.org)
Broad spectrum1
  • Benzethonium chloride exhibits a broad spectrum of microbiocidal activity against bacteria, fungi, mold and viruses. (wikipedia.org)
Bacteria1
  • It has the power of Mother Nature blended together with modern chemical compounds to protect your skin from various disease-causing germs, viruses, and bacteria and washes away odor providing you with a scent that everyone will enjoy. (reviewsicon.com)
Antiseptics1
  • As early as 1822, a French pharmacist demonstrated that solutions containing chlorides of lime or soda could eradicate the foul odors associated with human corpses and that such solutions could be used as disinfectants and antiseptics ( 2 ). (cdc.gov)
Vitro4
  • Therefore, this study aimed to compare the bioactivity of the NIEHS Division of Translational Toxicology's (DTT) 87-compound developmental neurotoxicant (DNT) library in zebrafish and an in vitro high-throughput cell culture system. (bvsalud.org)
  • We have shown that this compound has potent anti-leishmanial activity in vitro [6]. (who.int)
  • All compounds were in an initial screen evaluated against the L3 larval stage in vitro. (biomedcentral.com)
  • Active compounds were followed up first against adult worms in vitro, and promising compounds were tested in vivo. (biomedcentral.com)
Activity1
  • Benzalkonium Chloride has powerful potentiating activity in combination with other anti-microbial agents. (vizagchemical.com)
Products3
  • citation needed] The US Food and Drug Administration (FDA) specifies that the safe and effective concentrations for benzethonium chloride are 0.1-0.2% in first aid products. (wikipedia.org)
  • Benzalkonium Chloride (BKC) safely incorporates both Microbicidal & Detergency Properties into Products for Soil Penetration & Disinfection, which makes it ideal for the Formulation of Hygiene Products for Personal Hygiene, Hospital, Livestock and Food & Dairy use. (vizagchemical.com)
  • The polyphenols themselves are unstable, but are chemically converted into more stable substances that belong to a diverse class of products, called quaternary ammonium compounds. (naturalhealthgarden.ca)
Mixture1
  • A mixture of alkylbenzyldimethylammonium compounds. (jefferson.edu)
Toxic2
  • Quaternary ammonium compounds can cause toxic effects by all routes of exposure including inhalation, ingestion, dermal application and irrigation of body cavities. (inchem.org)
  • 70%. Excluding topical and toxic compounds, three drugs progressed into in vivo studies. (biomedcentral.com)
Solutions1
Product1
  • Benzethonium chloride in the Consumer Product Information Database Tentative final monograph (21CFR 333) Archived May 22, 2014, at the Wayback Machine Data Sheets National Toxicology, Program (1995). (wikipedia.org)
Methods1
  • The compounds, compositions, and methods disclosed herein address these and other needs. (justia.com)
Chemical2
  • QUATERNARY AMMONIUM COMPOUNDS International Programme on Chemical Safety Poisons Information Monograph G022 (Group PIM) Chemical 1. (inchem.org)
  • Benzalkonium Chloride (BKC) has diverse applications in the Chemical Industry as Precipitant, Phase Transfer Catalyst, Emulsifier/De-Emulsifier, etc. (vizagchemical.com)
Powder1
  • Benzalkonium chloride occurs as a white or yellowish white amorphous powder, a thick gel, or gelatinous flakes. (inchem.org)
Skin1
  • The compound is an inhibitor of mammalian protein kinase and has been applied topically for the treatment of skin metastasis showing good local tolerability [5]. (who.int)