Components protein complexes carrier proteins. Medical search. Frequent questions

The subunits are held together and connected to the underlying cell surface by non-covalent interactions, and they spontaneously reassemble in vitro by an entropy-driven process, i.e. the subunit proteins are very poorly water-soluble [ 8 ]. (biomedcentral.com)
A mouse model of HPS bears a point mutation altering a single amino acid within the VPS33A subunit of the HOPS/CORVET endolysosomal tethering complex. (chop.edu)
Int6 and p116, another putative eIF3 subunit, behave similarly, suggesting that eIF3 is a dynamic complex. (ox.ac.uk)
An adaptor protein subunit of MTORC2 COMPLEX. (bvsalud.org)

For membrane proteins, a third mechanism, based on the interaction of their transmembrane domain (TMD) with lipid microdomains, must also be considered. (biologists.com)
In this Commentary, I review evidence in favor of the idea that partitioning of TMDs into bilayer domains that are endowed with distinct physico-chemical properties plays a pivotal role in the transport of membrane proteins within the early secretory pathway. (biologists.com)
The combination of such self-organizational phenomena with canonical intermolecular interactions is most likely to control the release of membrane proteins from the ER into the secretory pathway. (biologists.com)
This process depends on the general physico-chemical features of the cargo membrane protein and on the interactions of these features with the collective properties of the bilayer, instead of the one-to-one intermolecular interactions that exist between discrete signals and their receptors. (biologists.com)
As a test-case, the membrane protein FepA is investigated in its full environment, yielding a more precise description of the protein surface. (nature.com)
Membrane proteins, such as those operating transport through the membrane in a controlled way, are prone to show interesting topological properties related to their function. (nature.com)
Our study uses classical algorithms such as space partitions and Dijkstra paths search 9 , applied in an original and novel way by taking into account the full representation of a membrane protein including the solvent and the lipid bilayer (Fig. 1 ). (nature.com)
The FepA membrane protein is surrounded by a lipid bilayer separating the extracellular medium and the periplasm. (nature.com)
Eight of the top ten over-expressed genes are known components of the egg yolk or perivitelline membrane. (biomedcentral.com)
the team and its collaborators have shown that the products of HPS-associated genes in skin melanocytes regulate two pathways of membrane protein transport from endosomes to newly forming melanosomes and a retrograde pathway from melanosomes. (chop.edu)
The lab is testing the role of lipid modifying enzymes in regulating the recruitment of BLOC-1 and BLOC-2 to membranes and in regulating the activity of other components of the membrane transport process. (chop.edu)
Fas-activated DCs increase the expression of MHC II, B7 co-stimulatory molecules, and DC-lysosome-associated membrane proteins (DC-LAMP), and secrete proinflammatory cytokines such as IL-1β and TNF-α. (biolegend.com)
April 22, 2021 -- A new cell-free synthetic biology technique that increases the volume of membrane components in the manufacture of conjugate vaccines can significantly improve the efficiency of vaccine production, according to a new method published in Nature Communications on April 22. (scienceboard.net)
These membrane vesicles have been identified as components that enhance bacterial CFE systems but have mostly been underappreciated. (scienceboard.net)
For a variety of organisms, close to 30% of the genome is used to encode membrane proteins," said co-author Neha Kamat, PhD, assistant professor of biomedical engineering at McCormick. (scienceboard.net)
Membrane proteins are a really important part of life. (scienceboard.net)
By learning how to use membrane proteins effectively, we can really advance cell-free systems. (scienceboard.net)
This low concentration explains how the inefficiency of previous CFE systems is derived from limitations of membrane protein synthesis, namely the fact that additional vesicle supplementation needed to match protein levels. (scienceboard.net)
The electron carriers then enter the electron transport chain, located in the inner mitochondrial membrane, where oxidative phosphorylation takes place. (microbiologynote.com)
Platelets play a primary role in this process, interacting with subendothelium-bound von Willebrand factor (vWf) via the membrane glycoprotein (GP) Ib complex. (medscape.com)

Cellular metabolism, involving the synthesis and breakdown of complex organic molecules, requires harmonious coordination of the various enzymes, biochemical reactions, and so forth. (newworldencyclopedia.org)
Among other things, biocatalytically active proteins (enzymes) can produce an incredible variety of complex biomolecules with potential applications ranging from basic chemicals and fuels to food additives and pharmaceuticals. (biooekonomie.de)
As versatile and advantageous as the biological synthesis of valuable substances is, it requires not only identifying and genetically optimizing appropriate enzymes, but also efficient production and purification of the target protein, because the single-celled organisms used for protein production also produce a lot of other compounds. (biooekonomie.de)
This compound is involved in the activity of a group of mitochondrial enzymes called the dehydrogenase complexes, one of which is the alpha-ketoglutarate dehydrogenase complex. (medlineplus.gov)
Ribozymes have been found in all types of organisms and are similar to protein-based enzymes, as they both increase the rate of reactions. (jove.com)
Enzymes and other proteins use ATP to power reactions, maintain ion gradients across membranes, contract muscle fibers, and transport molecules across cellular membranes. (microbiologynote.com)
The number of different molecular species in protein hydrolysates (observed with MS) can be high due to (1) the production of hydrolysates by chemical hydrolysis and/or enzymes with broad specificity, (2) the presence of partial modification sites, (3) the (original) presence of non-linear structure elements, and (4) the formation of multiple charge states and/or adduct types during analysis. (springer.com)

Due to their large surface area and ability to interact with proteins and peptides, graphene oxides offer valuable physiochemical and biological features for biomedical applications and have been successfully employed for optimizing scaffold architectures for a wide range of organs, from the skin to cardiac tissue. (mdpi.com)

The SLC25A19 gene provides instructions for producing a protein that is a member of the solute carrier (SLC) family of proteins. (medlineplus.gov)

It has been suggested that in the body it complexes with carrier proteins to prevent degradation, or exists as a component of a large precursor molecule, but as yet no structure or gene has been found for this precursor. (wikipedia.org)
Usually DNA remains as a giant molecule packed in the cells nucleus and is composed of proteins in the chromatin fibers. (scialert.net)
RNA acts as a messenger between DNA and the protein synthesis complexes known as ribosomes, forms vital portions of ribosomes, and serves as an essential carrier molecule for amino acids to be used in protein synthesis. (wikidoc.org)

A metabolic disorder is any disease or disorder that negatively affects the biochemical reactions through which individual animal cells process nutrient molecules (such as the components of carbohydrates , proteins , and fats ) to yield energy or perform the functions necessary to sustain life (such as building complex molecules and creating cellular structure). (newworldencyclopedia.org)
in the absence of a particular enzyme, the abnormal or unregulated synthesis of complex molecules might result. (newworldencyclopedia.org)
Sometimes these processes are attractive because the molecules would be too complex for conventional chemical synthesis. (biooekonomie.de)
Hyaluronan binding protein 1 (HABP1), also known as C1qBP/C1qR and p32, is a ubiquitous acidic glycoprotein that functions in spermatogenesis and as a receptor for proinflammatory molecules (1, 2). (rndsystems.com)
Cell surface HABP1 binds a wide range of extracellular molecules, including hyaluronan, vitronectin, complement component C1q, HMW kininogen, and bacterial and viral proteins (2, 6 - 9). (rndsystems.com)
At Biogen, we are developing a diverse portfolio consisting of small molecules, proteins, antisense oligonucleotides and gene therapy to target many neurodegenerative diseases. (chi-peptalk.com)
The resulting acetyl-CoA molecules enter the Krebs cycle, generating additional carbon dioxide, ATP, and electron carriers (such as NADH and FADH2). (microbiologynote.com)
These processes require energy to synthesize complex molecules necessary for cellular growth, maintenance, and functioning. (microbiologynote.com)
Through a series of interconnected metabolic pathways, the potential energy stored in the chemical bonds of these molecules is harnessed and transferred to energy carriers, which power other essential cellular processes. (microbiologynote.com)
The main role of DNA molecules is the long-term storage of information and DNA is often compared to a set of blueprints, since it contains the instructions needed to construct other components of cells, such as proteins and RNA molecules. (wikidoc.org)

60% of human protein-coding genes, mostly by binding to the 3′- untranslated region (3′UTR) of the target mRNAs ( 5 ) and, therefore, miRNAs affect gene expression networks of a variety of biological processes including development, apoptosis, proliferation, and metabolism ( 1 , 2 ). (frontiersin.org)
HPS types 7, 8 and 9 are due to mutations in genes encoding subunits of BLOC-1, a complex required for the generation of tubular cargo carriers destined for melanosomes. (chop.edu)
HPS types 3, 5 and 6 are due to mutations in genes encoding subunits of BLOC-2, a complex that directs BLOC-1-dependent cargo carriers with melanosomes. (chop.edu)
One basic problem is how a decrease in tRNA levels, by downregulating Pol III efficiency, influences the expression pattern of protein-coding genes. (mdpi.com)
Genes implicated in atopic dermatitis are those encoding epidermal and immunologic proteins. (msdmanuals.com)

Secretory proteins exit the endoplasmic reticulum (ER) in coat protein complex II (COPII)-coated vesicles and then progress through the Golgi complex before delivery to their final destination. (biologists.com)

Newly produced antibody, like the other plasma proteins, became readily labelled with S35 amino acids within a few hours. (caltech.edu)
The transfer of the major egg yolk proteins such as Very Low Density Lipoproteins (VLDL) containing essentially apovitellenin and apolipoprotein-B, but also vitellogenins and some other plasma proteins from the blood such as serum albumin to the interstitial fluid of the thecae is possible due to the presence of broad discontinuities in the capillary endothelium. (biomedcentral.com)

In contrast to expectations, none of the major S-layer proteins of the IPEC-1 -adhering strains mediated bacterial adherence. (biomedcentral.com)
They are composed of numerous identical (glyco)protein subunits (with a 25-71 kDa size in lactobacilli), which form a regular, symmetric and porous array, completely covering the bacterial cell surface. (biomedcentral.com)

Attempts were made to confer insolubility on protein antigens such as ovalbumin and crystalline bovine serum albumin without destroying their antigenicity. (caltech.edu)
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. (rndsystems.com)

Protein synthesis and lipogenesis are highly stimulated in the liver at sexual maturity in hens (15 to 20 fold) to support the incorporation of 0.75 kg proteins and 1.5 kg of triglycerides into the yolk over a year of commercial production. (biomedcentral.com)
Cells require a constant supply of energy to perform vital functions, including nutrient uptake, protein synthesis, DNA replication, and active transport across cell membranes. (microbiologynote.com)

Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. (rndsystems.com)
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. (rndsystems.com)
Serial dilutions of Mouse IL-11 Recombinant Protein were added to B9 cells. (cellsignal.com)
The purity of Mouse IL-11 Recombinant Protein was determined by SDS-PAGE of 1 µg reduced (+) and non-reduced (-) recombinant mIL-11 and staining with Coomassie Blue. (cellsignal.com)
Mouse IL-11 Recombinant Protein is supplied as lyophilized material that is very stable at -20°C. It is recommended to reconstitute with sterile water at a concentration of 0.1 mg/ml which can be further diluted in aqueous solutions as needed. (cellsignal.com)
The 397 amino acid recombinant protein has a predicted molecular mass of approximately 44.7 kD. (biolegend.com)
BioLegend carrier-free recombinant proteins provided in liquid format are shipped on blue-ice. (biolegend.com)

Predicted malonyl-CoA:ACP transferase, putative component of a type-II mitochondrial fatty acid synt. (yeastrc.org)

Given the tight relation between protein structure and function, we present a set of methods to analyze protein topology, implemented in the VLDP program, relying on Laguerre space partitions built from series of molecular dynamics snapshots. (nature.com)
The Laguerre space partition is the basis underlying all the implemented topological analysis methods: inter-atomic, inter-residue or inter-molecular contacts, connected components of the bulk or of the surface, optimal paths, porosity, genus of the surface, stratification. (nature.com)
The most common and cost-effective purification method is based on enabling the protein to bind to a specific surface structure by means of a molecular attachment known as a tag," Pecher explains. (biooekonomie.de)
Although HD is monogenic, its molecular manifestation appears highly complex and involves multiple cellular processes. (nature.com)
However, there are significant challenges due to inherent molecular complexity of proteins. (chi-peptalk.com)
The form of this complex can be controlled by variations of DNA`s molecular weight and types. (scialert.net)
In this paper is demonstrated that one example of the biologically important and molecular self-assembling complex system is a collagen-DNA ordered aggregates spontaneously formed in aqueous solutions. (scialert.net)
According to molecular biology data, the assembly of the complex between collagen and DNA determines the stability of DNA against the nucleases and indicates a development of autoimmune reaction (Poverenny, 1968). (scialert.net)
Accordingly it is very important study the principles of organization of the molecular complex between collagen and DNA. (scialert.net)
Mrevlishvili and Svintradze (2005a, b) is demonstrated that one example of biological important and molecular self-assembly complex system is the collagen-DNA ordered aggregate which is spontaneously formed in aqueous solution. (scialert.net)
According to the molecular model (Mrevlishvili and Svintradze, 2005b) DNA containing well-arranged phosphate groups helps to make this complex and these groups and water layers play key roles during collagen-DNA ordered aggregation in aqueous solution. (scialert.net)
One of the key molecular events in skin sensitization is protein haptenation, i.e. the chemical modification of self-skin protein(s) thus forming macromolecular immunogens. (cdc.gov)
The basis of hapten- molecular mechanisms of the sensitization pro- protein binding work is the hypothesis that upon cess will result in novel opportunities for the skin absorption, only protein-reactive chemicals development of alternative methods for assessing (or those that can be metabolically or chemically skin sensitization hazard and relative potency of converted to protein-reactive species) are able to chemicals. (cdc.gov)

Moreover, PRIN2 and CSP41b form a distinct protein complex in vitro that binds DNA. (frontiersin.org)
The target protein thus binds to the support material, other proteins can be washed off, and finally the target protein is released from the matrix in a chemical reaction without contamination from other proteins. (biooekonomie.de)
DNA binds to collagen directly to form DNA-collagen complex. (scialert.net)

The coat on the budding vesicle comprises two layers, an inner layer of adaptor proteins (gray ovals) and an outer layer that forms a polyhedral cage. (biologists.com)

FAS is a type I transmembrane protein and belongs to the TNF receptor superfamily. (biolegend.com)
Smith UM, Consugar M, Tee LJ, McKee BM, Maina EN, Whelan S. The transmembrane protein meckelin (MKS3) is mutated in Meckel-Gruber syndrome and the wpk rat. (medscape.com)

Lastly, we observed differential rod and core pigment responses to nitrogen deprivation, suggesting that PBS complexes undergo a stepwise degradation process. (osti.gov)

Human HTT codes for a large protein of 3144 amino acids, which is ubiquitously expressed in various tissues and is present in several sub-cellular locations. (nature.com)
Subsequently, caspase 8 is released from DISC and induces activation of caspase 3 and 7, proteolysis of cellular components, and apoptosis. (biolegend.com)
Cell-free gene expression (CFE) systems activate transcription and translation using crude cellular components instead of living, intact cells. (scienceboard.net)
Cellular respiration is a vital metabolic process that occurs within cells, enabling the conversion of energy stored in carbohydrates into energy carriers, most notably adenosine triphosphate (ATP). (microbiologynote.com)
The energy released during cellular respiration, in the form of ATP and other energy carriers, fuels various anabolic processes within the cell . (microbiologynote.com)

MMDB and VAST+: tracking structural similarities between macromolecular complexes. (nih.gov)

These data indicate a functional link between components of the structurally related eIF3 translation initiation and 26S proteasome complexes. (ox.ac.uk)

These include 37 proteases and antiproteases, which are likely to play a role in the formation of the yolk (vitellogenesis), as regulators of protein metabolism. (biomedcentral.com)

Moreover, the role of the L. amylovorus surface (S) -layers - symmetric, porous arrays of identical protein subunits present as the outermost layer of the cell envelope - in adherence to IPEC-1 cells was assessed using a novel approach which utilized purified cell wall fragments of the strains as carriers for the recombinantly produced S-layer proteins. (biomedcentral.com)

Exosomes, microvesicles, and apoptotic bodies are considered as carriers of extracellular miRNAs ( 21 ). (frontiersin.org)
More than 90% of extracellular miRNAs are vesicle-free, but form a complex with proteins such as Agonaute2 (AGO2) ( 22 , 23 ). (frontiersin.org)

Therefore, it is expected that when the correlation between the shape of complex and uptake of the complex into the cell is clarified, the efficiency of introduction of DNA into cells with the use of collagen will increase even more. (scialert.net)
Three types of samples, the dissolved start products, in vitro generated dialysates (containing the digested components that are potentially available for small intestinal absorption), and human serum collected after product ingestion, were analyzed using LC-MS to compare the state of the hydrolysates before and after absorption, i.e., uptake into the blood. (springer.com)
For subjects suffering from reduced absorptive capacity, it can be an option to consume protein in hydrolyzed form to facilitate the uptake of essential amino acids [ 1 ]. (springer.com)

Thus, the principle of protein or peptide haptenation could be used in in vitro assays to predict the sensitization potential of a new chemical entity. (cdc.gov)

Drosha, RNase III, and DGCR8, the RNA-binding protein, further process pri-miRNAs into stem-loop structured precursor miRNAs (pre-miRNAs) of ~70 nt ( 29 ). (frontiersin.org)
AF237571_1 malonyl CoA-acyl carrier protein transacylase precursor [Plasmo. (yeastrc.org)

This complex coordination can be disrupted through a genetic defect in an enzyme. (newworldencyclopedia.org)
But the heavy metal ions that entered the solutions during enzyme purification interacted in unfavorable ways with various components of the enzyme reactions. (biooekonomie.de)
They can self-splice without the help of any proteins, whereas nuclear introns are spliced by the spliceosome, an RNA and protein-containing enzyme complex. (jove.com)

They found that vesicles are varied in size and are relatively low in concentration compared with ribosomes and other small complexes. (scienceboard.net)

In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere. (rndsystems.com)

suggest that DSIP interacts with components of the MAPK cascade and is homologous to glucocorticoid-induced leucine zipper (GILZ). (wikipedia.org)
Sum1, a component of the fission yeast eIF3 translation initiation complex, is rapidly relocalized during environmental stress and interacts with components of the 26S proteasome. (ox.ac.uk)

Some success has been obtained also in the formation of antibodies from other serum proteins and by other denaturation-renaturation procedures. (caltech.edu)
Collagen extraction from tissues such as bone or skin is usually performed under acidic or alkaline conditions and/or heating, which will result in protein denaturation and in non-specific cleavage of peptide bonds. (springer.com)

Although heterogeneous in their origin, cancer-associated fibroblasts have common properties distinct from normal fibroblasts and show expression of proteins not found in their normal counterparts. (snmjournals.org)
Transport by partitioning is distinct from both bulk flow and receptor-mediated transport, because differently from bulk flow, cargo can be concentrated in transport carriers, yet the concentrating process does not depend on specific cargo receptors ( Fig. 1 and Box 1 ). (biologists.com)
Three hundred and sixteen distinct proteins have been identified in egg yolk. (biomedcentral.com)

The platelet GP IIb/IIIa complex mediates platelet-to-platelet interactions (platelet aggregation). (medscape.com)
Platelet activation allows binding of these proteins, which bridges adjacent platelets. (medscape.com)
The alpha granules contain hemostatic proteins such as fibrinogen, vWf, and growth factors (eg, platelet-derived growth factor and transforming growth factors). (medscape.com)

All known individuals with Amish lethal microcephaly have a mutation in which the protein building block (amino acid) alanine is substituted for the amino acid glycine at position 177 of the SLC25A19 protein, written as Gly177Ala or G177A. (medlineplus.gov)
Compared with intact protein, the ingestion of protein hydrolysate accelerates protein digestion and absorption in the gut, increases amino acid availability after passage through the stomach, and tends to increase the incorporation rate of dietary amino acids into skeletal muscle protein [ 2 ]. (springer.com)

The biological functions of Lactobacillus S-layer proteins (Slp:s) are not well understood. (biomedcentral.com)
The biological activity of soluble antigen-antibody complexes: II. (caltech.edu)
These results raise the question of the biological significance of egg yolk proteases and antiproteases, and more generally of all minor proteins that have been identified in egg yolk. (biomedcentral.com)

The lab is using a number of approaches to define the SNAREs involved in fusion of BLOC-1-dependent carriers with maturing melanosomes and to understand how their localization and activity are regulated. (chop.edu)
The data further show that B9d1 is required for normal Hedgehog (Hh) signaling, ciliogenesis, and ciliary protein localization. (medscape.com)

The problem of obtaining from precipitation experiments evidence about the structure of antibodies and the nature of serological reactions is obviously greatly simplified by the replacement of protein antigens by simple substances of known structure. (caltech.edu)
The naturally available ribozymes are known to catalyze a narrow range of reactions such as phosphoryl transfer in nucleic acids and peptide bond formation in proteins. (jove.com)
CFE reactions based on the use of Escherichia coli can quickly synthesize grams of protein per liter in batch reactions, are scalable from the nanoliter to 100-L scale, and can be freeze-dried for months of shelf stability. (scienceboard.net)

Cost-effective, sufficient, vegan, gluten-free, cruelty-free, nutrient-rich, and free of dangerous chemicals were all factors considered in the search for the best stem cell masks , as well as having scientifically proven, organic, and natural components. (brandsreviews.com)
Previous ensemble studies have shown that cyanobacteria respond to changes in nutrient availability by modifying the structure of PBS complexes, but this process has not been visualized for individual pigments at the single-cell level due to spectral overlap. (osti.gov)

Thus, pathogens must have specific mecha- clearly complex, and, in many cases, the study of these nisms for mediating colonization, avoiding the host's interactions is limited by the lack of a suitable animal immune system, and acquiring necessary nutrients. (cdc.gov)

These cytoplasmic foci, which additionally comprise eIF4E and RNA components, may function as translation centers during environmental stress. (ox.ac.uk)

Hapten-heterologous carrier conjugates elicited antihapten titers similar in magnitude to those elicited by the homologous carrier conjugate. (caltech.edu)
In the current study, the researchers found that increasing vesicle concentration could be useful in making components for protein therapeutics such as conjugate vaccines, which work by attaching a sugar unit -- which is unique to a pathogen -- to a carrier protein. (scienceboard.net)

Pigment cell-specific transmembrane proteins SLC45A2 and OCA2 are a transporter and channel, respectively, that modulate melanosome pH at different stages of melanosome maturation and that are targets of mutation in different forms of oculocutaneous albinism. (chop.edu)
Cyanobacterial phycobilisome (PBS) pigment-protein complexes harvest light and transfer the energy to reaction centers. (osti.gov)

In this method, ions that can interact with the tag of the target protein are tightly bound to a support material, the solid-state matrix. (biooekonomie.de)

The cell recognizes the shape of DNA-collagen complex, and effectively takes up complexes of certain shapes. (scialert.net)

However, searches through BLAST have found that it aligns with a hypothetical Amycolatopsis coloradensis protein. (wikipedia.org)

We show here that PLASTID REDOX INSENSITIVE 2 (PRIN2) and CHLOROPLAST STEM-LOOP BINDING PROTEIN 41 kDa (CSP41b), two proteins identified in plastid nucleoid preparations, are essential for proper plant embryo development. (frontiersin.org)
Taken together, our results suggest that PEP activity and consequently the switch from NEP to PEP activity, is essential during embryo development and that the PRIN2-CSP41b DNA binding protein complex possibly is important for full PEP activity during this process. (frontiersin.org)
Egg yolk constitutes a major source of proteins, minerals, vitamins and lipids for the developing embryo. (biomedcentral.com)

Proteins in the SLC family transport various compounds across the membranes surrounding the cell and its component parts. (medlineplus.gov)
The living cell exists as a result of processes that generate complex, multi-component, functional structures by self-assembly. (scialert.net)
Filaggrin is a component of the cornified cell envelope produced by differentiating keratinocytes. (msdmanuals.com)
It functions as a structural component and is phosphorylated by RIBOSOMAL PROTEIN S6 KINASES, integrating signals for cell growth and proliferation, especially during embryonic development. (bvsalud.org)

IL-22 signals through a receptor complex consisting of IL-22 R and IL-10 R beta. (rndsystems.com)
Thus, JPT2 is a component of the NAADP receptor complex that is essential for TPC-dependent Ca 2+ signaling and control of coronaviral entry. (nih.gov)

This review critically focuses on opportunities to employ protein-graphene oxide structures either as nanocomposites or as biocomplexes and highlights the effects of carbonaceous nanostructures on protein conformation and structural stability for applications in tissue engineering and regenerative medicine. (mdpi.com)

We demonstrated adhesive and significant pathogen inhibitory efficacies among the swine intestinal L. amylovorus strains studied, pointing to their potential use as probiotic feed supplements, but no independent role could be demonstrated for the major S-layer proteins in adherence to epithelial cells. (biomedcentral.com)

Our comparison testing data indicates that when handled and stored as recommended, the liquid format has equal or better stability and shelf-life compared to commercially available lyophilized proteins after reconstitution. (biolegend.com)

Passively administered homologous antibody did not produce a change in the retention of the primary injection of antigen nor did secondary injections of a heterologous native protein injected according to the same immunization schedule as the homologous azoprotein. (caltech.edu)

The lab employs a variety of approaches to probe how BLOC-1 interacts with membranes and with other HPS-encoded protein complexes to better understand its mechanism of action. (chop.edu)

Such extraordinary complex induces distraction hydration shell of collagen triple helix, stabilization hydration shell of ds-DNA, stability of DNA against the nucleases and this complex between collagen and DNA determines unusual properties of collagen fibers. (scialert.net)

Most of the circulating testosterone is bound to carrier proteins (SHBG = sex hormone-binding globulin). (cdc.gov)

Ribonucleic acid, or RNA, is a nucleic acid polymer consisting of nucleotide monomers, which plays several important roles in the processes of translating genetic information from deoxyribonucleic acid (DNA) into proteins. (wikidoc.org)

The main components are the blood cells such as white blood cells, red blood cells, and platelets. (emedicinehealth.com)

Researchers believe that this mutation interferes with the transport of thiamine pyrophosphate into the mitochondria and the activity of the alpha-ketoglutarate dehydrogenase complex, resulting in the abnormal brain development and alpha-ketoglutaric aciduria seen in Amish lethal microcephaly. (medlineplus.gov)

The CusB protein is part of the CusCBA periplasmic Cu(I) efflux system in Gram-negative bacteria, and it was recently reported to play a key role in the functioning of the whole CusCBA system, in which conformational changes as well as the assembly/disassembly process control the opening of the transporter. (biorxiv.org)
A new purification process promises environmentally friendly extraction of proteins for the food and pharmaceutical industries. (biooekonomie.de)
This process provides the necessary energy for complex organisms with higher energy demands. (microbiologynote.com)

Fusion of transport carriers with target organelles is mediated by SNARE proteins. (chop.edu)
Sex hormone-binding globulin (SHBG) is the blood transport protein for testosterone and estradiol. (cdc.gov)

IL-11 belongs to the interleukin-6 (IL-6)-type subfamily of long-chain helical cytokines, including IL-6, ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), oncostatin M, and cardiotrophin-1, which all share the glycoprotein gp130 as a signal transducing receptor component. (cellsignal.com)

Anatomy12

Organisms15

Chemicals and Drugs130

Analytical, Diagnostic and Therapeutic Techniques and Equipment32

Phenomena and Processes62

Disciplines and Occupations2

Technology, Industry, Agriculture3

Information Science6

Health Care2

Subunit4

Membrane20

Enzymes7

Peptides1

Solute1

Molecule3

Molecules10

Genes5

Endoplasmic reticulum1

Plasma proteins2

Bacterial2

Bovine serum a2

Synthesis2

Recombinant7

Mitochondrial1

Molecular13

Binds3

Adaptor1

Transmembrane protein2

Degradation1

Cellular5

Macromolecular1

Structurally1

Metabolism1

Subunits1

Extracellular2

Uptake3

Vitro1

Precursor2

Enzyme3

Ribosomes1

Contrast1

Interacts with components2

Denaturation2

Distinct3

Platelet3

Amino acid2

Biological3

Localization2

Reactions3

Nutrient2

Interactions1

Cytoplasmic1

Conjugate2

Pigment2

Interact1

Effectively1

Hypothetical1

Embryo3

Cell4

Receptor complex2

Structural1

Strains1

Shelf-life1

Homologous1

Mechanism1

Stability1

Bound1

Nucleic1

Platelets1

Mutation1

Process3

Transport2

Cytokines1