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  • liver iron
  • The UTE MRI will give an accurate value of liver iron in patients with large iron deposits in the liver, therefore providing an accurate means to diagnose, monitor, and provide treatments for participants. (clinicaltrials.gov)
  • The technique will then be tested in research participants, who will have both the R2*-GRE and the R2*-UTE techniques performed, in addition to a liver biopsy for liver iron quantitation if clinically indicated. (clinicaltrials.gov)
  • blood
  • In blood plasma, iron is carried tightly bound to the protein transferrin. (wikipedia.org)
  • A lack of sufficient iron levels in the blood is a reason that some people cannot donate blood. (wikipedia.org)
  • Possible reasons that athletics may contribute to lower iron levels includes mechanical hemolysis (destruction of red blood cells from physical impact), loss of iron through sweat and urine, gastrointestinal blood loss, and haematuria (presence of blood in urine). (wikipedia.org)
  • patients
  • Volunteer purpose: To test the UTE MRI to ensure it runs correctly before testing in patients, collect data of normal values of iron in the liver in people without iron overload using the UTE MRI and to compare the current MRI (GRE) with the UTE. (clinicaltrials.gov)
  • amounts of iron
  • Although small amounts of iron are excreted in sweat and urine, these losses can generally be seen as insignificant even with increased sweat and urine production, especially considering that athletes' bodies appear to become conditioned to retain iron better. (wikipedia.org)