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  • pore
  • In this section learn that an activated protein is transported into the nucleus through a pore in the nuclear membrane. (dnalc.org)
  • The exchange of macromolecules between the nucleus and cytoplasm takes place through nuclear pore complexes within the nuclear membrane. (ebi.ac.uk)
  • Computational and biochemical identification of a nuclear pore complex binding site on the nuclear transport carrier NTF2. (nih.gov)
  • Nuclear transport carriers interact with proteins of the nuclear pore complex (NPC) to transport their cargo across the nuclear envelope. (nih.gov)
  • The product of this gene, adenine nucleotide translocator 2 (ANT2), functions as a major constituent of the mitochondrial permeability-transition pore complex that catalyzes the exchange of mitochondrial ATP with cytosolic ADP. (wikipedia.org)
  • The generalized transport reaction catalyzed by members of the Amt family are suggested to be: NH4+ (out) ⇌ NH4+ (in) The X-ray structures have revealed that the pore of the Amt and Rh proteins is characterized by a hydrophobic portion about 12 Å long, in which electronic density was observed in the crystallographic study of AmtB from Escherichia coli. (wikipedia.org)
  • This deactivation is achieved by deuridylylation of the GlnK protein which then binds to the cytoplasmic face of AmtB and inserts a loop into the ammonia conducting pore. (wikipedia.org)
  • Ionophores can disrupt the membrane potential by conducting ions through a lipid membrane in the absence of a protein pore, and thus could exhibit cytotoxic properties. (wikipedia.org)
  • Escherichia
  • The crystal structure of the complex of the enzyme from Escherichia coli, and the fungal mycotoxin cerulenin reveals that the inhibitor is bound in a hydrophobic pocket formed at the dimer interface. (rcsb.org)
  • The three-dimensional structure of the ammonia transport protein AmtB from Escherichia coli has been determined by x-ray crystallography revealing a hydrophobic ammonia channel. (wikipedia.org)
  • biosynthesis
  • The activity of the fatty acid (FA) reductase complex from Photorhabdus luminescens was coupled with aldehyde decarbonylase from Nostoc punctiforme to use free FAs as substrates for alkane biosynthesis. (pnas.org)
  • One pathway for lysine biosynthesis uses a carrier protein, LysW, to protect the substrate. (scoop.it)
  • Fatty-acyl-CoA Synthase, or more commonly known as yeast fatty acid synthase (and not to be confused with Long Chain fatty acyl-CoA synthetase), is an enzyme complex responsible for fatty acid biosynthesis, and is of Type I Fatty Acid Synthesis (FAS). (wikipedia.org)
  • The biosynthesis of Tyrocidine is similar to Gramicidin S, and is achieved through the use of nonribosomal protein synthetases (NRPSs). (wikipedia.org)
  • Its biosynthesis is via an enzymatic assembly consisting of 3 peptide synthetase proteins, TycA, TycB, and TycC, which contain 10 modules. (wikipedia.org)
  • Receptors
  • inducing T-cell response (prolonged exposure of peptide-MHC complexes [signal and stimulation of expression of T-cell-activating co-stimulators [signal on the APCs' surface) and targeting (e. g. carbohydrate adjuvants which target lectin receptors on APCs). (wikipedia.org)
  • Clathrin coats contain both clathrin (acts as a scaffold) and adaptor complexes that link clathrin to receptors in coated vesicles. (wikipedia.org)
  • The majority of synthetic receptors used in the carrier-based anion-selective electrodes employ transition elements or metalloids as anion carriers, although simple organic urea- and thiourea based receptors are known. (wikipedia.org)
  • enzyme
  • In vitro it has been found to have a low molecular stability with a half life of only 15 minutes due to the action of a specific aminopeptidase-like enzyme. (wikipedia.org)
  • A mildly effective enzyme that can also attach to the wall of certain bacteria, degrade selected proteins and interfere with the ability of the bacteria to replicate themselves. (colostrum.com)
  • The catalytic activities of this enzyme complex involves a coordination system of enzymatic reactions between the alpha and beta subunits. (wikipedia.org)
  • The enzyme complex therefore consists of six functional centers for fatty acid synthesis. (wikipedia.org)
  • The type I FAS system utilizes a multi-enzyme complex, which are highly integrated, while the type II FAS system utilizes individual, separate enzymes to catalyze the reactions involved in fatty acid synthesis. (wikipedia.org)
  • The 3D protein structure of the enzyme can be found here:PDB. (wikipedia.org)
  • ACP is the only "mobile" domain of the enzyme complex, in which it moves intermediate substrates along all of the catalytic centers the enzyme, most notably the alpha and beta subunits. (wikipedia.org)
  • Each module uses one molecule of the selected substrate amino acid with one molecule of ATP to give an aminoacyl adenylate enzyme complex and pyrophosphate. (wikipedia.org)
  • The activated amino acid can then be transferred to the enzyme bound 4'-phosphopantetheine of the carrier protein with the expulsion of AMP from the system. (wikipedia.org)
  • glycosylation
  • In spite of this, knowledge on glycosylation of proteins other than S-layer proteins in Archaea is quite limited. (scoop.it)
  • Here, the N-glycosylation pattern of cell-surface-exposed proteins of Sulfolobus solfataricus P2 were analyzed by lectin affinity purification, HPAEC-PAD, and multiple mass spectrometry-based techniques. (scoop.it)
  • Remarkably, we show that several other proteins in the surface fraction of S. solfataricus are N-glycosylated by the same sulfated oligosaccharide and we identified 56 N-glycosylation sites in this subproteome. (scoop.it)
  • As a result of these advances, recent efforts have not only succeeded in delineating the pathways involved in archaeal N-glycosylation, but also begun to reveal how such post-translational protein modification helps archaea to survive in some of the harshest environments on the planet. (scoop.it)
  • It was found that efficiency of glycosylation but not carrier protein expression was highly susceptible to the physiological state at induction. (nih.gov)
  • After induction glycoconjugates generally appeared later than unglycosylated carrier protein, suggesting that glycosylation was the rate-limiting step for synthesis of conjugate vaccines in E. coli. (nih.gov)
  • Both encode large glycosylated proteins consisting of around 3400 amino acids and a molecular weight of around 390,000 Daltons, excluding the glycosylation. (wikipedia.org)
  • residues
  • Frataxin chaperones iron to the matrix side of ferrochelatase, where aspartate and histidine residues on both proteins coordinate iron transfer into ferrochelatase. (wikipedia.org)
  • metabolism
  • Multiple studies have suggested the existence of an oligomeric complex that enables substrate channeling and coordination of overall iron and porphyrin metabolism throughout the cell. (wikipedia.org)
  • ions
  • Each ferritin complex can store about 4500 iron (Fe3+) ions. (wikipedia.org)
  • If the protein becomes denatured or if the copper ions are lost in the purification process, the opalescent blue color disappears and the solution becomes a dull grayish color. (wikipedia.org)
  • Ionophore means "ion carrier" as these compounds catalyze ion transport across hydrophobic membranes such as liquid polymeric membranes (carrier-based ion selective electrodes) or lipid bilayers found in the living cells or synthetic vesicles (liposomes) Some ionophores are synthesized by microorganisms to import ions into their cells. (wikipedia.org)
  • structural
  • In agreement with these results, mutations in the inhA structural gene have been found in INH-resistant clinical isolates of M.tuberculosis, the causative agent of TB. (rcsb.org)
  • Consequently, yeast FAS is incredibly unique due to its structural complexity, which contains 48 functional centers for one α6β6 complex and can efficiently performs 6 fatty acid syntheses separately at one time. (wikipedia.org)
  • PMID
  • it interacts with leucine-rich nuclear export signal (NES) sequences in proteins to be transported, as well as with RanGTP [ PMID: 9323132 , PMID: 9323123 ]. (ebi.ac.uk)
  • it interacts with RanGTP and importin-alpha, the latter binding with the nuclear localisation signal (NLS) sequences in proteins to be transported [ PMID: 17170104 ]. (ebi.ac.uk)
  • mammalian
  • In addition, because KLH is derived from the limpet, a gastropod, it is phylogenetically distant from mammalian proteins, thus reducing false positives in immunologically-based research techniques in mammalian model organisms. (wikipedia.org)
  • Cytokines
  • This includes cytokines and mitogens with crucial function in complex processes such as inflammatory response or tumor-induced angiogenesis. (wikipedia.org)
  • hydrophobic
  • The benzoquinone and isoprenyl units are both nonpolar, anchoring the molecule within the inner section of a lipid bilayer, where the hydrophobic tails are usually found. (wikipedia.org)
  • subunits
  • It is a 2.6 MDa barrel shaped complex and is composed of two, unique multi-functional subunits: alpha and beta. (wikipedia.org)
  • Adaptins are distantly related to the other main type of vesicular transport proteins, the coatomer subunits, sharing between 16% and 26% of their amino acid sequence. (wikipedia.org)
  • AP complexes are heterotetramers composed of two large subunits (adaptins), a medium subunit (mu) and a small subunit (sigma). (wikipedia.org)
  • Ferritin is a globular protein complex consisting of 24 protein subunits forming a nanocage with multiple metal-protein interactions. (wikipedia.org)
  • Ferritin is a hollow globular protein of 450 kDa consisting of 24 subunits that is present in every cell type. (wikipedia.org)
  • It was proposed[citation needed] that the erythrocyte Rh complex is a heterotrimer of RhAG, RhD, and RhCE subunits in which RhD and RhCE might play roles in anchoring the ammonia-conducting RhAG subunit to the cytoskeleton. (wikipedia.org)
  • vesicular
  • Clathrin adaptor proteins, also known as adaptins, are vesicular transport adaptor proteins associated with clathrin. (wikipedia.org)
  • The two major types of clathrin adaptor complexes are the heterotetrameric vesicular transport adaptor proteins (AP1-5), and the monomeric GGA (Golgi-localising, Gamma-adaptin ear homology, ARF-binding proteins) adaptors. (wikipedia.org)
  • Soluble proteins can reach the surface of the cell both by non-vesicular and vesicular mechanism. (wikipedia.org)
  • Non-vesicular mechanism use a carrier to get protein into extracellular space (for example phosphatidylinositol-4,5-bisphoshate). (wikipedia.org)
  • conjugate
  • Synthetic Peptide Representing a T-Cell Epitope of CRM197 Substitutes as Carrier Molecule in a Haemophilus Influenzae Type b (HIB) Conjugate Vaccine", Advances in Exper. (patentgenius.com)
  • Effect of immunity to the carrier protein on antibody responses to Haemophilus influenzae type b conjugate vaccines", Vaccine,11(1):546-551, (1993). (patentgenius.com)
  • Oligosaccharide-Protein Conjugate Vaccines Induce and Prime for Oligoclonal IgC Antibody Responses to the Haemophilus influenzae by Capsular Polysaccharide in Human Infants",J. Exp. (patentgenius.com)
  • Carrier-induced epitope-specific regulation and its bypass in a protein-protein conjugate", Eur. (patentgenius.com)
  • Conjugate vaccines in which polysaccharide antigens are covalently linked to carrier proteins belong to the most effective and safest vaccines against bacterial pathogens. (nih.gov)
  • unlike
  • This family of enzymes is found only in the plastids of higher plant cells, unlike other desaturases such as acyl-lipid desaturases and acyl-CoA desaturases. (wikipedia.org)
  • Unlike hemocyanin and hemoglobin, hemovanadin is not an oxygen carrier. (wikipedia.org)
  • Antigens
  • Two different periplasmic carrier proteins, AcrA from C. jejuni and a toxoid form of Pseudomonas aeruginosa exotoxin were glycosylated with Shigella O antigens in E. coli. (nih.gov)
  • This change possesses a greater number of possible conjugated antigens to the protein. (wikipedia.org)
  • Golgi
  • Immunoelectron microscopic study revealed that the perinuclear EAAC1 immunoreactivity corresponded to the translocation to the Golgi complex. (biomedsearch.com)
  • Hemocyanin
  • Keyhole Limpet Hemocyanin (KLH) It is copper-containing respiratory protein, isolated from keyhole limpets (Megathura crenulata). (wikipedia.org)
  • Concholepas Concholepas Hemocyanin (CCH) (also Blue Carrier Immunogenic Protein) It is alternative to KLH isolated from Concholepas concholepas.It has the similar immunogenic properties as KLH but better solubility and therefore better flexibility. (wikipedia.org)
  • Keyhole limpet hemocyanin (KLH) is a large, multisubunit, oxygen-carrying, metalloprotein that is found in the hemolymph of the giant keyhole limpet, Megathura crenulata, a species of keyhole limpet that lives off the coast of California, from Monterey Bay to Isla Asuncion off Baja California. (wikipedia.org)
  • In the absence of oxygen, the bound copper is found as Cu1+ and hemocyanin is colorless. (wikipedia.org)
  • Keyhole limpet hemocyanin (KLH) is used extensively as a carrier protein in the production of antibodies for research, biotechnology and therapeutic applications. (wikipedia.org)
  • Sulfolobus
  • Sulfolobus metallicus was found to be a strict aerobic chemolithotroph because it oxidizes sulphur contained in minerals such as pyrite, chalcopyrite, elemental sulfur and sphalerite into sulfuric acid. (wikipedia.org)
  • Induce
  • Small proteins produced by various cells in the body that induce the generation of specialized types of white blood cells, signal them to come to the site of an insult and help in their passage through tissues. (colostrum.com)
  • We can define an immunogen as a complete antigen which is composed of the macromolecular carrier and epitopes (determinants) that can induce immune response. (wikipedia.org)
  • bacteria
  • Another mineral-binding carrier protein that attaches to available iron and can act independently or in concert with lactoferrin to impede the growth of certain aerobic bacteria, particularly in the gut. (colostrum.com)
  • Tyrocidine is a mixture of cyclic decapeptides produced by the bacteria Bacillus brevis found in soil. (wikipedia.org)
  • Ammonia transporters (TC# 1.A.11) are structurally related membrane transport proteins called Amt proteins (ammonia transporters) in bacteria and plants, methylammonium/ammonium permeases (MEPs) in yeast, or Rhesus (Rh) proteins in chordates. (wikipedia.org)
  • structure
  • Illustration of the structure of a low-density lipoprotein (LDL) particle, a form of cholesterol found in the blood. (sciencephoto.com)
  • Ribosome: A structure made up of proteins and RNA that is the site of protein production in the cell. (dnalc.org)
  • Indeed, mechanisms that involve large fluctuations of the membrane structure, such as transient pores and the insertion of charged amino acid side-chains, may be common and perhaps central to the functions of many membrane protein functions. (wikipedia.org)
  • Having one monosaccharide unit more than the glycan of the S-layer glycoprotein of S. acidocaldarius, this is the most complex archaeal glycan structure known today. (scoop.it)
  • The function and structure of the expressed ferritin protein varies in different cell types. (wikipedia.org)
  • The human RhCG ammonia transporter was found to have a similar ammonia-conducting channel structure. (wikipedia.org)
  • The structure of the ammonia channel from E. coli, was, at the time of its publication, the highest resolution structure of any integral membrane protein. (wikipedia.org)
  • The structure of the sodium and potassium complexes of antibiotics have been verified by X-ray crystallography. (wikipedia.org)
  • The proteins: composition, structure, and function. (wikipedia.org)
  • sequence
  • SSO1273 protein is heavily glycosylated and all 20 theoretical N-X-S/T (where X is any amino acid except proline) consensus sequence sites were confirmed. (scoop.it)
  • These proteins contain a specific signal-peptide sequence, which is to be translated into the endoplasmic reticulum, but are, however, able to reach the cell surface unconventionally. (wikipedia.org)
  • Lipoproteins
  • Fatty acids are components of phospholipids and sphingolipids which are part of biological membranes, fats (triglycerides) which are used as energy storage devices inside cells (adipose tissue), function as fat transport vehicle in the blood (high and low density lipoproteins), and through covalent attachment are used for protein modification. (whatislife.com)
  • nuclear
  • One such carrier is nuclear transport factor 2 (NTF2), whose import cargo is the small GTPase Ran. (nih.gov)
  • Two types of unconventional protein secretion are these: signal-peptid-containing proteins and cytoplasmatic and nuclear proteins that are missing an ER-signal peptide (1). (wikipedia.org)
  • tissues
  • DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif: N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. (wikipedia.org)
  • Small proteins produced in response to the body's exposure to certain types of microorganisms, particularly those that reside in deep tissues for a long period of time, like the bacterium that causes tuberculosis. (colostrum.com)
  • nucleus
  • For example, messenger RNA carries the information to make a protein from the nucleus to a ribosome, while transfer RNA delivers amino acids to a ribosome during protein production. (dnalc.org)
  • amino acid
  • It is a complex POLYMER formed from the amino acid TYROSINE (4-hydroxphenylalanine) by oxidation via dopa and dopaquinone. (thefreedictionary.com)
  • Translocation of glutamate transporter subtype excitatory amino acid carrier 1 protein in kainic acid-induced rat epilepsy. (biomedsearch.com)
  • We examined the temporal expression of the sodium-dependent neuronal glutamate transporter, excitatory amino acid carrier 1 (EAAC1), in KA-induced rat epilepsy. (biomedsearch.com)
  • This is accomplished through the subdomains for adenylation (A), peptityl carrier protein (PCP), condensation (C), and depending on the amino acid position, an epimerization (E). The adenylation subdomain is used in activating the specific amino acid. (wikipedia.org)
  • In certain domains you will find modification subdomains, such as the E subdomain seen in domains 1 and 4 in tyrocidine, which will generate the D-configured amino acid. (wikipedia.org)
  • mechanism
  • The mechanism of this mutation, however, was unknown as this region of NTF2 had not been implicated in binding to NPC proteins. (nih.gov)
  • Triclosan (sometimes abbreviated as TCS), similar in its uses and mechanism of action to triclocarban, is an antibacterial and antifungal agent found in some consumer products, including toothpaste, soaps, detergents, toys, and surgical cleaning treatments. (wikipedia.org)
  • Toxoid
  • Immunogens Consisting of Oligosaccharides from the Capsule of Haemophilus influenzae Type b Coupled to Diphtheria Toxoid or the Toxin Protein CRM197",J. Clin. (patentgenius.com)
  • yeast
  • This domain is found close to the N terminus of yeast exportin 1 (Xpo1, Crm1, P14068 ), as well as adjacent to the N-terminal domain of importin-beta ( IPR001494 ). (ebi.ac.uk)
  • Yeast fatty acyl synthase, of Type I FAS, is composed of a α6β6 complex in which an αβ unit forms one functional center for fatty acid synthesis. (wikipedia.org)
  • Mainly
  • As an early alteration, perinuclear deposits of EAAC1 protein were found mainly in the large pyramidal neurons at the hippocampus, neocortex, piriform cortex, and amygdala with the reduction of neuropil staining 6 hours after KA injection. (biomedsearch.com)
  • Infect
  • Antibody Responses to Haemophilus influenzae Type b and Diphtheria Toxin Induced by Conjugates of Oligosaccharides of the Type b Capsule with the Nontoxic Protein CRM",Infect. (patentgenius.com)
  • immunogenic
  • Consequently, the haptens themselves are nonimmunogenic and they cannot evoke an immune response until they bind with a larger carrier immunogenic molecule. (wikipedia.org)
  • serum
  • Serum ferritin" presents a paradox, as the iron storage protein ferritin is not synthesised in serum yet is to be found there. (rsc.org)
  • The protein in serum ferritin is considered benign, but it has lost ( i.e. dumped) most of its normal complement of iron which when unliganded is highly toxic. (rsc.org)
  • Taking a systems approach, we develop and summarise the view that "serum ferritin" actually originates from damaged cells (and thus reflects cellular damage), that it contains some iron but has lost or liberated most of its normal content, and that since the protein part of ferritin is assumed to be benign, that it is this (initially) free iron that correlates with and is causative of disease. (rsc.org)
  • As such, many lipid signaling molecules cannot circulate freely in solution but, rather, exist bound to special carrier proteins in serum. (wikipedia.org)
  • membrane
  • Expression of mislocalized mutant syntaxin 3 in Madin-Darby canine kidney cells leads to basolateral mistargeting of apical membrane proteins, disturbance of tight junction formation, and loss of ability to form an organized polarized epithelium. (rupress.org)
  • These results indicate that SNARE proteins contribute to the overall specificity of membrane trafficking in vivo, and that the polarity of syntaxin 3 is essential for epithelial cell polarization. (rupress.org)
  • organisms
  • For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all known organisms, being found in species as diverse as the unicellular bacterium Escherichia coli and huge multicellular organisms like elephants. (wikipedia.org)
  • mutations
  • 28 COMMON DEFECTS OF POLARIZATION ELEMENT Here we list some common defects found in real polarization elements.97 Myers, L. GlnA mutations conferring resistance to methylammonium in Escherichia coli K12. (imbc-med.ru)
  • Carriers of germline mutations in CDKN2A have besides their high risks of melanoma also increased risks of pancreatic, lung, laryngeal and oropharyngeal cancers and tobacco smoking exacerbates carriers' susceptibility for such non-melanoma cancers. (wikipedia.org)
  • lipid
  • Gen. 74 Curr.Oakes, J. Chromatographic profiles after incubation of lipid-ODNLDL complexes with rat plasma. (imbc-med.ru)
  • The increase in the sugar carrier dolichyl phosphate may reflect an increased rate of glycosylation in the diseased brain, and the increase in the endogenous anti-oxidant ubiquinone an attempt to protect the brain from oxidative stress, for instance, induced by lipid peroxidation. (wikipedia.org)
  • The core area of ribosomes is surrounded by a single cisterna of endoplasmic reticulum, two to three mitochondria, and an extensive microbody-lipid globule complex. (wikipedia.org)
  • Topical antiaging compounds that are currently under investigation include photoprotectors, such as cinnamidopropyltrimonium chloride and solid lipid nanoparticles as carriers for UV blockers, oral supplementation with l-cystine and l-methionine, and topical melatonin. (wikipedia.org)
  • coat
  • If an embryo has not initiated the thinning process naturally, a small "window" is created chemically in the wall of the protein coat using a dilute acidic solution pulsed onto the embryo surface through an extremely fine glass needle. (arizonafertility.com)
  • recruit
  • When promoters use the SAGA/TATA box complex to recruit RNA polymerase II, they are more highly regulated and display higher expression levels than promoters using the TFIID/TBP mode of recruitment. (wikipedia.org)
  • belongs
  • This protein belongs to the LDLR family and is made up of a number of functionally distinct domains, including 3 EGF-like domains, 7 LDL-R class A domains, and 6 LDL-R class B repeats. (wikipedia.org)
  • premature
  • Nutritional deficiencies like vitamin B12 deficiency, severe iron deficiency, chronic protein loss, copper deficiency are often found associated with premature greying of hairs. (wikipedia.org)
  • As hair pigmentation is a result of complex interaction between various genetic factors, it is thought that premature greying could be due to exhaustion of melanocyte's capability to produce hair pigmentation. (wikipedia.org)
  • immune responses
  • Proteins are also important in cell signaling, immune responses, cell adhesion, active transport across membranes, and the cell cycle. (wikipedia.org)
  • Because these proteins are recognised as foreign, when they are processed by the host cells and displayed on their surface, the immune system is alerted, which then triggers immune responses. (wikipedia.org)
  • mutation
  • A single-nucleotide polymorphism (SNP) is a genetic variation in which a genome sequence is altered by a single nucleotide (A, T, C or G). NET proteins with an altered amino acid sequence (more specifically, a missense mutation) could potentially be associated with various diseases that involve abnormally high or low plasma levels of norepinephrine due to altered NET function. (wikipedia.org)
  • cellular
  • Metabolism is usually divided into two categories: catabolism, the breaking down of organic matter for example, the breaking down of glucose to pyruvate, by cellular respiration, and anabolism, the building up of components of cells such as proteins and nucleic acids. (wikipedia.org)
  • cell
  • The C-terminal domain of Beta2-adaptin is a protein domain is involved in cell trafficking by aiding import and export of substances in and out of the cell. (wikipedia.org)
  • Homozygous deletion of p16 are frequently found in esophageal cancer and gastric cancer cell lines. (wikipedia.org)
  • NETs are restricted to noradrenergic neurons and are not present on neurons that release dopamine or epinephrine.The transporters can be found along the cell body, axons, and dendrites of the neuron. (wikipedia.org)
  • The same results were found for certain inducers of apoptosis particularly stimulators of receptors in a class of lymphocytes (a type of white blood cell) called B-cells. (wikipedia.org)
  • cells
  • HTLV-I provirus was more methylated in primary ATL cells than in carrier state, indicating the association with disease progression. (biomedcentral.com)
  • The DNA is injected into cells, whose "inner machinery" uses the DNA to synthesize the proteins. (wikipedia.org)
  • detect
  • Spotted fever can be very difficult to diagnose in its early stages, and even experienced doctors who are familiar with the disease find it hard to detect. (wikipedia.org)
  • genetic
  • It is a complex multi-factorial process mainly considered to be an interplay of nutritional, genetic and environmental factors. (wikipedia.org)
  • A catalogue of the many uses of these techniques can be found in the section: genetic testing. (wikipedia.org)
  • Catalogues of more than 50,000 tests available worldwide can be found at GeneTests and Genetic Testing Registry. (wikipedia.org)
  • Carrier testing is typically offered to individuals who are considering pregnancy or are already pregnant, have a family history of a specific genetic disorder and to people in ethnic backgrounds that have an increased risk of specific genetic conditions. (wikipedia.org)
  • PGD can be utilized by individuals or couples who are affected by a condition of genetic origin, or if both individuals are found to be carriers of a recessive genetic condition. (wikipedia.org)
  • regulate
  • Together with histone acetylases (HATs), HDACs regulate acetylation level of histones (H3, H2AK5, H4K5, H4K12, H2B, H4K8, and H4K16) as well as some other proteins (p65 and myocyte enhancer factor 2) [ 5 ]. (hindawi.com)
  • different
  • In evolution, luciferins vary little: one in particular, coelenterazine, is found in eleven different animal (phyla), though in some of these, the animals obtain it through their diet. (wikipedia.org)
  • function
  • For instance, artificial parthenogenesis proved that it was possible to separate the sperm's function as initiator of development from its role as carrier of the male hereditary characters. (devbio.com)
  • less
  • But, as with the science of genomics, ELSI research reveals a more complex situation that is less amenable to definitive conclusions than often portrayed. (biomedcentral.com)
  • present
  • As far as I can find, at present the state of the art regarding it seems to be (A) a big shrug, and (B) the suggestion that it's an irrelevant side effect - the sort of thing that should make Larry Moran happy. (iayork.com)
  • type
  • The carriers of C alleles presented with lower thickness of subcutaneous tissue and higher concentrations of HDL-C than the wild type. (biomedcentral.com)
  • large
  • In the 1980s the DNA microarray appeared, permitting laboratories to find copy number variants associated with disease that are below the level of detection of cytogenetics but too large to be detected by DNA sequencing. (wikipedia.org)
  • small
  • Proteins synthesized on the ribosome and processed in the endoplasmic reticulum are transported from the Golgi apparatus to the trans-Golgi network (TGN), and from there via small carrier vesicles to their final destination compartment. (wikipedia.org)
  • Research
  • Compound semiconductors and germanium, whose carrier mobility is superior to that of silicon, are called post-silicon materials, and research into them is proceeding in various countries as next-generation channel materials. (nanowerk.com)
  • Numerous research works have focused interest on defining the direct protein targets of action of ceramide. (wikipedia.org)