• I developed a novel multidimensional protein fractionation system called PROOF, with a novel graphical interpretation and representation of the peptide data related back to the elution of the proteins from the PROOF system. (edu.au)
  • Ciechanover, A. Intracellular protein degradation: from a vague Idea, through the lysosome and the ubiquitin-proteasome system, and onto human diseases and drug targeting (Nobel Lecture). (nature.com)
  • Biosynthesis, structure and biological activities of envelope protein gp65 of murine coronavirus. (uci.edu)
  • from the coding potential of DNA through to the regulated activity of proteins and large protein complexes. (umu.se)
  • In terms of pharmaceutical production, the egg is a really great system because it produces a lot of protein. (thenakedscientists.com)
  • Biologists have found that a key protein that regulates the biological clocks of mammals also regulates glucose production in the liver and that altering the levels of this protein can improve the health of diabetic mice. (scienceblog.com)
  • Protein performs its biological functions by interacting with other proteins. (lu.se)
  • Protein complexes, which are formed as a result of these interactions, consist of two or more components that associate along specific pathways - protein association pathways. (lu.se)
  • The spatial and temporal ranges accessible using the technique of quasi-elastic neutron scattering (QENS) are ideally matched to the atomic and molecular vibrational displacements, correlation lengths and diffusive motions encountered in highly complex biological systems. (benthamscience.com)
  • Thus, through many years of refining scientific ingenuity and skill, present-day molecular biologists now have at their disposal an extensive molecular toolbox capable of tackling and answering most biological problems. (umu.se)
  • Students will be able to improve their capacity for critical thinking through a detailed analysis and evaluation of scientific concepts and experimental designs in advanced molecular biological research. (umu.se)
  • By enabling both time resolution and structural detail Time-Resolved Small Angle X-ray/Neutron Scattering (TR-SAXS/TR-SANS) is uniquely suited to interrogate complex self-assembly reactions and to provide a molecular understanding of self-assembly pathways. (lu.se)
  • Compounds and molecular complexes that consist of very large numbers of atoms and are generally over 500 kDa in size. (bvsalud.org)
  • However, in contrast to mononuclear systems, the multidimensional dynamics of the PSS in solvated molecular arrays have not yet been elucidated due to the expected complications associated with the connectivity between the metal centers and the strong interactions with the surroundings. (lu.se)
  • 1. the abstract approach to the theory behind these systems, 2. (aau.dk)
  • applications of the abstract theory to coupled structures like networks, neighbouring domains divided by permeable membranes, possibly non-homogeneous simplicial complexes, etc., and 3. (aau.dk)
  • In this study, the researchers give a mechanistic understanding of how the mutations in two different molecules interact, explains Mato Lagator: "Most excitingly, we show that - in this gene regulatory system - most of the epistasis arises from the genetic structure of the system. (ist.ac.at)
  • In this section, the basic principles of quasi-elastic neutron scattering pertinent to the study of dynamic processes in biological molecules are presented. (benthamscience.com)
  • These tools address generalized models used in systems biology, considering both dynamical and spatial distribution of the biological molecules with ordinary and partial differential equations. (purdue.edu)
  • Statistical mechanics is a branch of physics that uses statistical and probabilistic methods to understand the behaviour of large numbers of microscopic particles, such as atoms and molecules, in a system. (mpg.de)
  • make these clusters ideal as model systems to understand how the primary sequence of processes is affected by surrounding atoms or molecules. (lu.se)
  • Evolution of metal ions in biological systems refers to the incorporation of metallic ions into living organisms and how it has changed over time. (wikipedia.org)
  • Many organisms have flexible systems in which they can exchange one metal for another if one is scarce. (wikipedia.org)
  • Biomechanics is the study of the structure, function and motion of the mechanical aspects of biological systems, at any level from whole organisms to organs , cells and cell organelles , [1] using the methods of mechanics . (wikipedia.org)
  • Biological fluid mechanics, or biofluid mechanics, is the study of both gas and liquid fluid flows in or around biological organisms. (wikipedia.org)
  • Interactions among microscopic organisms in a complex medium such as soil are difficult to observe and quantify. (scirp.org)
  • The devices are unable to study more complex 3D biological organisms and systems. (photonics.com)
  • Her environmental developmental neuroimmunotoxicology research program explores relationships between biological organisms and their developmental responses after exposure to environmental toxicants. (cdc.gov)
  • Metals are known to be involved in over 40% of enzymatic reactions, and metal-binding proteins carry out at least one step in almost all biological pathways. (wikipedia.org)
  • The aim of this thesis was to investigate and further develop a series of novel and emerging techniques in the field of proteomics, used for the identification and quantification of proteins in a range of complex biological systems. (edu.au)
  • I was also able to show that both quantitative techniques are comparative and identified similar biological insights, while the total number of proteins identified and quantified by spectral counting was proportionately larger, with 236 and 84 proteins for spectral counting and iTRAQ respectively. (edu.au)
  • The obvious next step is to integrate this information and learn how genes, proteins, and/or epigenetic factors influence the phenotype of a disease in context of the system. (rsc.org)
  • The biological system is complex with many regulatory features such as DNA, mRNA, proteins, metabolites, and epigenetic features such as DNA methylation and histone post-translational modifications (PTMs). (rsc.org)
  • The unit aims to provide an introduction to macromolecular recognition at the structural level, encompassing the widest range of examples, from small molecule recognition and drug design, through to recognition of proteins and nucleic acids, and how this drives biological function. (manchester.ac.uk)
  • And so, when you give these proteins to humans as a therapeutic, they are less likely to cause an immune response - a negative immune response and they're also more likely to be active compared to proteins made in other systems. (thenakedscientists.com)
  • Kat - So, if that complex biological system is the chicken's egg, how do you get the genes that make the proteins into the chickens? (thenakedscientists.com)
  • In this talk I will discuss three issues: what happens during the deformation of crystalline solids, which is related to collective dislocation dynamics, how such phenomena are indeed more universal and easy to see during creep deformation, and thirdly some ongoing work on the internal dynamics of complex suspension flows. (su.se)
  • Nonlinear dynamics are ubiquitous in natural and artificial systems. (google.com)
  • From climate, to lasers, viral dynamics and complex ecosystems. (google.com)
  • We use tools from dynamical systems theory and statistical physics to comprehend the mechanisms behind the dynamics and changes of states in nonlinear systems. (google.com)
  • To achieve our goals, NoDE is supported by a big network of enthusiastic collaborators working on dynamics, applied mathematics, systems and synthetic biology, as well as in field and theoretical ecology. (google.com)
  • qRT-PCR provided a sensitive method to investigate fungal dynamics over time in this multitrophic system. (scirp.org)
  • Salvatore Magazù, Federica Migliardo , " Dynamics of Biological Macromolecules by Neutron Scattering ", Bentham Science Publishers (2011). (benthamscience.com)
  • Biological membranes are complex multicomponent systems whose dynamics and structure provide their physiological function. (benthamscience.com)
  • He explains: "Mathematical analysis tools, typically in the domain of theorists, can be applied to simplified models of EBS to investigate the qualitative dynamics of the system. (europa.eu)
  • It is quite common that the dynamics arises as a compound effect of the interaction between sub-systems in which case we speak about coupled systems. (aau.dk)
  • Systems biology provides a theoretical framework that integrates as much information as possible from all functional levels to understand the system. (purdue.edu)
  • This course fulfills the requirement for students majoring in the biological sciences and satisfies the biology requirement for entrance into medical school. (princeton.edu)
  • This course is well suited for masters students at the department of Biology interested in biological modelling, how models work and what they are good for. (lu.se)
  • An atomistic understanding of the photoinduced spin-state switching (PSS) within polynuclear systems of d4-d7 transition metal ion complexes is required for their rational integration into light-driven reactions of chemical and biological interest. (lu.se)
  • Computational biomechanics is the application of engineering computational tools, such as the Finite element method to study the mechanics of biological systems. (wikipedia.org)
  • Mathematical and computational analysis tools are key to formally merge current biological knowledge and hypotheses underlying the mechanism of these systems. (purdue.edu)
  • This thesis discusses computational tools developed to acquire and integrate biological information. (purdue.edu)
  • Failure of Infant-Mother Eye-Contact in a Complex Adaptive System. (bvsalud.org)
  • This book draws on literature from the biological, behavioural and social sciences, including, psychology, sociology and sports performance analysis, to develop a detailed, interdisciplinary and multi-level picture of the elite sports team. (routledge.com)
  • Aretxaga is a class-C researcher at the National Institute of Astrophysics, Optics and Electronics (INAOE), Mexico, a member of the Mexican National Researcher System (equivalent to Full Professor), and a member of the Mexican Academy of Sciences (AMC). (twas.org)
  • Mathematical Modeling of Complex Biological Systems Simulations, Biological Interpretations, and Further Modelling Perspectives %22&body=%0AI%20found%20an%20article%20you%20might%20be%20interested%20in. (sagepub.com)
  • To explore the extent to which functional systems within the human posterior parietal cortex and the superior temporal sulcus are involved in the perception of action, we measured cerebral metabolic activity in human subjects by positron emission tomography during the perception of simulations of biological motion with point-light displays. (jneurosci.org)
  • The experimental paradigm used to explore the above questions involved simulations of biological motion in the three-dimensional space using point-light displays. (jneurosci.org)
  • Many physical, biological, chemical, financial or even social phenomena can be described by dynamical systems. (aau.dk)
  • The purpose of this Action is to bring together leading groups in Europe working on a range of issues connected with modelling and analysing mathematical models for dynamical systems on networks. (aau.dk)
  • It aims to develop a semigroup approach to various (non-)linear dynamical systems on networks as well as numerical methods based on modern variational methods and applying them to road traffic, biological systems, and further real-life models. (aau.dk)
  • The models that encode this knowledge, through mathematical equations and dynamical or spatial rates, are informed by experimental data through a relationship between various system inputs and outputs. (purdue.edu)
  • In this process, the intricate and orderly patterns are generated through simple interactions among a large number of components in a system 1 , 2 . (nature.com)
  • They can be found very early in Earth's fossil records (about 3.25 billion years ago) as both Archaea and Bacteria, and commonly protect prokaryotic cells by providing them with homeostasis, encouraging the development of complex interactions between the cells in the biofilm. (wikipedia.org)
  • Potential interactions between mixture components within biological systems are not well characterized. (cdc.gov)
  • Researchers at the Institute of Science and Technology Austria (IST Austria) found that in a gene regulatory system in the bacterium Escherichia coli, the more components that are mutated, the more freely the system can evolve. (ist.ac.at)
  • Genetically speaking, one point mutation changes the transcription factor so that the phenotype of our gene regulatory system changes by X, and the other point mutation changes the binding site so that the phenotype changes by Y. Now, when both mutations occur together, the phenotype is not simply X+Y, it is different. (ist.ac.at)
  • Complexity and Control in Team Sports is the first book to apply complex systems theory to 'soccer-like' team games (including basketball, handball and hockey) and to present a framework for understanding and managing the elite sports team as a multi-level complex system. (routledge.com)
  • Complexity in living systems - in nature and humans Chapter 3. (routledge.com)
  • Revealing the exact connections between chemical power supply and microbial diversity through analyses of natural environments is extremely challenging due to the high complexity and high number of unknown processes occurring in biological systems. (biorxiv.org)
  • Purpose - To illustrate the application of chromatic approaches to complexity with two illustrations each involving the interaction of two complex systems biological and polychromatic light. (deepdyve.com)
  • Model-based design of experiments (MBDOE) capitalizes on the uncertainty in the models to investigate how to perturb the real system to maximize the information obtained from experiments. (purdue.edu)
  • We use multi-objective optimization (MOO) to investigate how a single model could be used to fit multiple systems by changing parameters. (purdue.edu)
  • Here, we use mathematical modelling to investigate fundamental connections between chemical power supply to a system and its biological diversity and community structure. (biorxiv.org)
  • False-positive Mycobacterium tuberculosis complex (MTBC) results can be difficult to identify, investigate, and resolve. (cdc.gov)
  • We use these engineered Cas9 activation complexes to investigate sgRNA targeting rules for effective transcriptional activation, demonstrate multiplexed activation of 10 genes simultaneously, and upregulate long intergenic non-coding RNA (lincRNA) transcripts. (cdc.gov)
  • In the present positron emission tomography (PET) study, the use of moving point-light displays, instead of ordinary featural displays, permits appropriate experimental control because the visual stimuli in all conditions are the same and, therefore, any difference between these conditions is the result of the perceptual processing by the nervous system. (jneurosci.org)
  • You will study the nervous system, learning about the basics of a normal, functioning brain, as well as what happens when a brain is damaged or diseased and how we are able to fix it. (fandm.edu)
  • A knowledge of the biological foundation of the brain and nervous system. (fandm.edu)
  • Special emphasis research on early life exposure to a variety of agents that may affect the immune, nervous, and endocrine systems, resulting in altered development such as disease or disorder in childhood or later in life. (cdc.gov)
  • Her expertise lies in how impacts on the immune system lead to downstream effects on the nervous system. (cdc.gov)
  • Specially, we are interested in bifurcation phenomena governing complex biological systems. (google.com)
  • Unilateral or bilateral distal-extension removable partial dentures present complex biomechanics. (bvsalud.org)
  • Businesses, like biological ecosystems, are complex adaptive systems . (bcg.com)
  • and a player's complex physiological/biological system. (routledge.com)
  • Drawing these together, the book throws fascinating new light on the elite sports team and will be useful reading for all students, researchers or professionals with an interest in sport psychology, sport management, sport coaching, sport performance analysis or complex systems theory. (routledge.com)
  • Specifically, the global fellowship recipient Matthew Wade of Newcastle University integrated mathematical theory commonly used to describe industrial processes into models of engineered biological systems (EBS). (europa.eu)
  • A brief description of some of the non-Newtonian flow phenomena encountered in the flow of biological fluids. (rand.org)
  • Macromolecular recognition at the structural level is key to driving biological function. (manchester.ac.uk)
  • Fig. 2: Structural analysis of the human DCAF15-DDB1-DDA1-RBM39(RRM2) complex with indisulam. (nature.com)
  • The circadian system is a complex coordination of biological rhythms which help our body function. (cdc.gov)
  • MBDOE identifies the optimal conditions for stimuli and measurements that yield the most information about the system given practical limitations such as experimental cost and time, feasible inputs and measurements. (purdue.edu)
  • Despite its fundamental importance, experimental tests of Jarzynski's equality for classical and quantum systems are extremely challenging, since they require complete control in manipulating and measuring the system. (mpg.de)
  • The Second Law is a statement about the average properties of particles in a system undergoing a thermodynamic process, and postulates that heat always flows spontaneously from hotter to colder regions of the system. (mpg.de)
  • The association pathway from monomer to oligomer is critical in a range of biological processes and thus it is of a vital importance to elucidate both atomic-resolution structures of intermediates along the pathway as well as the structure of the final state. (lu.se)
  • Fig. 1: Functional validation of RBM39 and DCAF15-DDB1-DDA1 complexes. (nature.com)
  • Moreover, in hydrothermal systems, the chemical energy landscapes emerging from mixing between reduced hydrothermal fluids and oxygenated cold seawater, seem to shape distributions of functional groups of bacteria and archaea [ 22 , 23 ]. (biorxiv.org)
  • Design/methodology/approach - Gives details of algorithms used to encode data from images in established and new automatic iris recognition systems. (deepdyve.com)
  • With the advancement of next-generation sequencing and mass spectrometry, there is a growing need for the ability to merge biological features in order to study a system as a whole. (rsc.org)
  • such an interaction in this system might reduce the biocontrol efficacy of T. harzianum . (scirp.org)
  • To delineate the precise mechanism by which indisulam mediates the DCAF15-RBM39 interaction, we solved the DCAF15-DDB1-DDA1-indisulam-RBM39(RRM2) complex structure to a resolution of 2.3 Å. (nature.com)
  • One of the most remarkable relations in statistical mechanics is Jarzynski's equality, connecting the irreversible work performed in an arbitrary thermodynamic process with the energy and entropy of the system in thermodynamic equilibrium. (mpg.de)
  • Specifically, we use various DNA damaging methods, including laser microirradiation to study nucleus-wide epigenetic responses to complex DNA damage through PARP signaling and metabolic alteration. (uci.edu)
  • As a consequence, these methods can be broadly applied to a wide variety of biological applications as demonstrated in this work. (purdue.edu)
  • Purpose - To introduce chromatic methods and their application to monitoring complex systems. (deepdyve.com)
  • to both methods and systems. (lu.se)
  • We offer the courses Common Microscopy Methods in Biological Research (external website) and Microscopy - Bioimaging (external website) for PhD and Master students. (lu.se)
  • To date, various genome-scale loss-of-function screening methods have been developed, including approaches employing RNA interference 1 , 2 and the RNA-guided endonuclease Cas9 from the microbial CRISPR (clustered regularly interspaced short palindromic repeat) adaptive immune system 3 , 4 . (cdc.gov)
  • Engineers and physical scientists have been developing methods to mathematically represent complex cellular processes. (medlineplus.gov)
  • Moreover, we show how simple connections between power supply and growth can give rise to complex patterns of biodiversity across physicochemical gradients, such as pH gradients. (biorxiv.org)
  • Students look at the evolutionary ecology of mechanisms used by immune systems to recognize and kill parasites, finding similarities across animal taxa. (princeton.edu)
  • Near-death experiences (NDE) raise important questions about the nature of human consciousness, the relationship between brain function and consciousness, the perceptual information that is available to consciousness in moments before death, the role of physical and biological mechanisms associated with altered states of consciousness, and relationships between consciousness, space-time and phenomenal reality. (sfu.ca)
  • The system, together with the developed data processing algorithm, has the ability to assess architectural changes in the vascular network and its blood supply, as well as to identify periodic signal changes associated with mechanisms of blood flow oscillation of various natures. (bvsalud.org)
  • Achieving systematic, genome-scale perturbations within intact biological systems is important for elucidating gene function and epigenetic regulation. (cdc.gov)
  • But when we take a system composed of several components, such as a system that regulates gene expression, what happens when not only a single component is mutated, but several? (ist.ac.at)
  • The most popular microscopy technique for biological or biomedical studies by far is wide-field microscopy, in which a sample, such as tissue, is imaged through a digital camera. (photonics.com)
  • While many biological samples are 3D in nature, only a thin 2D plane is observable at any one time in traditional microscopy. (photonics.com)
  • At our microscopy platform in Lund, you meet personnel with expertise and long experience working with biological material and microscopy, imaging, and analysis. (lu.se)
  • In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure. (bvsalud.org)
  • Biotribology is the study of friction , wear and lubrication of biological systems, especially human joints such as hips and knees. (wikipedia.org)
  • This study contributes to get better knowledge how a metal ion is required to carry the quinolones to their site of action and also to clarify how metal surroundings affect the biological action of quinolones drugs. (hindawi.com)
  • The work could assist in a number of biomedical applications and in the study of dynamic systems. (photonics.com)
  • Purpose - To study the mathematical image coding approaches used in two types of biometric systems, and the physical nature of those biometrics. (deepdyve.com)
  • In a new joint study, an international team from the Max Planck Institute for the Physics of Complex Systems, the University of California at Berkeley, the Lawrence Berkeley National Laboratory, the German Cluster of Excellence ML4Q and the Universities of Cologne, Bonn, and Sofia identified quantum computers as a natural platform to test the validity of Jarzynski's equality for many interacting quantum particles. (mpg.de)
  • These external cues can be powerful, in that light exposure at different times of the day can shift the circadian system timing and alter sleep patterns (1). (cdc.gov)
  • The Action also explores the possibility of estimating solutions and long time behaviour of these systems by collecting basic combinatorial information about underlying networks. (aau.dk)
  • Understanding how environmental factors shape biological communities is a fundamental problem in microbial ecology. (biorxiv.org)
  • The issue is, without top-down intent, materially driven bottom-up causation undermines responsible rational freedom (so, mindedness) by reducing it to GIGO-driven computation on blind chance and/or mechanical necessity with of course a big lurking question being, where did such complex functionally coherent information-rich design come from, apart from design? (uncommondescent.com)
  • In this field, nanoparticles have notable importance due to their unique properties and characteristics, which are useful in different applications, including tissue engineering, biomarkers, and drug delivery systems. (mdpi.com)
  • Results of search for 'su:{Models, Biological. (who.int)
  • Invited lecture, 1970 International Seminar on Heat and Mass Transfer in Rheologically Complex Fluids. (rand.org)
  • These results are an interesting proof of concept, but the method still needs further development before it can be considered a working platform that can achieve both affinity capture and concentration of a biological sample mixture. (edu.au)
  • The US EPA sets National Ambient Air Quality Standards for criteria air pollutants, recognizing that air pollution in the environment exists as a complex mixture. (cdc.gov)
  • [13] The biofilm bacteria can share nutrients and are sheltered from harmful factors in the environment, such as desiccation, antibiotics, and a host body's immune system. (wikipedia.org)
  • A broad survey of the field of immunology and the mammalian immune system. (princeton.edu)
  • Through the statistical distribution of particle properties, such as energy and velocity, statistical mechanics helps us make predictions about how physical systems behave on a larger scale, contributing to our understanding of fundamental principles in physics and chemistry. (mpg.de)
  • Because the system is free to leave the equilibrium state during its evolution, Jarzynski's equality is a prime example of how equilibrium physics can constrain the outcome of nonequilibrium processes. (mpg.de)
  • Arthur Genthon of the Max Planck Institute for the Physics of Complex Systems, Albertas Dvirnas and Tobias Ambjörnsson (Lund University, Sweden) have now derived an exact equilibrium solution of an extended Poland-Scheraga model that describes DNA with a defect site that could, for instance, result from DNA basepair mismatching, cross-linking, or the chemical modifications from attaching fluorescent labels, such as fluorescent-quencher pairs, to DNA. (mpg.de)
  • In order to improve and expand applications of Cas9, we recently undertook crystallographic studies to elucidate the atomic structure of the Cas9-sgRNA-target DNA tertiary complex 14 , thus enabling rational engineering of Cas9 and sgRNA. (cdc.gov)
  • The association between implants / removable partial denture aims to provide better mechanical and biological properties to the stomatognathic system. (bvsalud.org)
  • Purpose - Aims to develop an efficient and robust system for real‐time personal identification by automatic face recognition. (deepdyve.com)
  • Recently, respiratory systems in insects have been studied for bioinspiration for designing improved microfluidic devices. (wikipedia.org)
  • An often studied liquid biofluid problem is that of blood flow in the human cardiovascular system. (wikipedia.org)
  • I was able to get the iTRAQ labelling to work in a plant system, particularly rice leaf material that had undergone temperature stress. (edu.au)
  • In the present work we reported the synthesis, characterization, and biological activity results of a copper mixed complex (see Figure 1 ), with hsm and nalidixic acid. (hindawi.com)
  • Why do immune systems work as they do? (princeton.edu)
  • Purpose - Reports on the work of the National Physical Laboratory in evaluating commercial biometric authentification systems. (deepdyve.com)
  • The work considers a theranostic system that implements a multimodal approach allowing the simultaneous generation of singlet oxygen and visualization of the various parameters of the vascular bed. (bvsalud.org)
  • In this work, the PSS in a solvated triiron(II) metallogrid complex is characterized using transient optical absorption and X-ray emission spectroscopies on the femtosecond time scale. (lu.se)
  • Pattern formation caused by self-organization is a fascinating phenomenon that appears in biological, chemical, and physical systems. (nature.com)
  • In all living systems there are a special set of four chemical 'letters,' called nucleotides, which are used to 'write' the information stored by the code of life, the Genetic Code. (bibliotecapleyades.net)
  • However, nucleotides are much more complex than the simple amino acids made by Miller and Urey, and would require much more chemical expertise to produce. (bibliotecapleyades.net)
  • We reveal a strong mechanistic coupling between biological diversity and the diversity of chemical power supply, but also find that different properties of power supply, such as substrate fluxes and flow and Gibbs energies of reactions, affect community structure in fundamentally different ways. (biorxiv.org)
  • His research helped to scale the biological control of vectors of Malaria in Nicaragua and laid the foundation of ecological management of agroforestry systems in Mesoamerica. (twas.org)
  • Simplifying underlying models to accommodate integration of high-level analyses has enabled a step change in qualitative insight regarding complex microbe-based processes for a sustainable future. (europa.eu)
  • The associated complexes have evolved over time. (wikipedia.org)
  • The extra daylight hours may allow for more fun in the sun, but we may want to consider how these changes in light and time can influence our circadian system and disrupt our sleep. (cdc.gov)
  • When we obtain more exposure to evening light, our brain and circadian system may delay sleep causing us to have more difficulty falling asleep at our normal time. (cdc.gov)
  • This course can be taken in parallel with BIOS14 Processing and Analysis of Biological Data, as both are given part time. (lu.se)
  • This is helping accelerate the growth of engineered biological systems that span from one single cell all the way to multicellular systems, like engineered organs. (medlineplus.gov)
  • This highlighted the proof of concept for the application of PROOF to a complex and important proteome such as human plasma, and brought to light truncated or cleaved elements within this proteome that standard bottom-up proteomic analysis could not identify. (edu.au)
  • These results showed that in our hands, spectral counting was more viable than iTRAQ for quantitative proteomic analysis in plant systems. (edu.au)
  • A mixed copper complex with deprotonated nalidixic acid (nal) and histamine (hsm) was synthesized and characterized by FTIR, UV-Vis, elemental analysis, and conductivity. (hindawi.com)
  • Fig. 3: DDA1 stabilizes the DCAF15-DDB1 complex and impacts degradation of RBM39 by indisulam. (nature.com)
  • The properties of water in biological systems have been studied for well over a century by a wide range of physical techniques, but progress has been slow and erratic. (lu.se)
  • The properties of water in biological systems have been are discussed, we emphasize magnetic-relaxation tech- studied for well over a century by a wide range of physical niques and, in particular, MRD. (lu.se)
  • We describe structure-guided engineering of a CRISPR-Cas9 complex to mediate efficient transcriptional activation at endogenous genomic loci. (cdc.gov)
  • While lesser detail and simplifying assumptions of the underlying predictive model may reduce quantitative accuracy, qualitative insights are vital to planning and optimisation of biological treatment processes. (europa.eu)