• Unstable coronary artery plaque is the most common underlying cause of acute coronary syndromes (ACS) and can manifest as unstable angina, non-ST segment elevation infarction (NSTE-ACS), and ST elevation myocardial infarction (STEMI), but can also manifest as sudden cardiac arrest due to ischaemia induced tachyarrhythmias. (romanianjournalcardiology.ro)
  • However, such figures are misleading, and short term (in-hospital) outcome is still better for NSTE-ACS than for STEMI, while the longer term mortality rate is higher for NSTE-ACS, but this is probably influenced by the different age and risk structure of the STEMI and NSTE-ACS populations: NSTE-ACS patients are generally older and often have multivessel (MV) coronary artery disease (CAD). (romanianjournalcardiology.ro)
  • Consequently, OCT is a valuable research tool for examining the role of morphological characteristics of atheromatous plaques in the progression of coronary artery disease and plaque destabilisation, which leads to the clinical manifestation of ACS. (ecrjournal.com)
  • They assessed the extent and severity of atherosclerosis in the aorta, coronary, carotid, and cerebral arteries, demonstrating that the cerebral arteries were free from atherosclerosis up to the fourth decade, almost 20 to 30 years later than extracranial arteries like coronary and carotid artery [ 5 - 7 ]. (j-stroke.org)
  • Not only started later in life, ICAS was much slighter in the amount and extent than aorta and coronary artery atherosclerosis for all decades [ 5 , 8 ]. (j-stroke.org)
  • The alterations observed in middle cerebral artery (MCA) in the 6th decade were similar to those in the radial artery in 4th decade and that in the coronary artery in 2-3th decades [ 9 ]. (j-stroke.org)
  • 5. Sasayama S, Fujita M, Nonogi H , Kawai C, Eiho S, Kuwahara M: Quantitative assessment of regional disorders of left ventricular wall motion in patients with coronary artery disease by cine-ventriculography. (fiercecert.com)
  • 6. Sasayama S, Nonogi H , Fujita M, Sakurai T, Wakabayashi A, Kawai C, Eiho S, Kuwahara M: Three-dimensional analysis of regional myocardial function in response to nitroglycerin in patients with coronary artery disease. (fiercecert.com)
  • 8. Nonogi H , Sasayama S, Miyazaki S, Asanoi H, Yamanishi K, Kawai C, Eiho S, Kuwahara M: Modification of pacing-induced alterations in diastolic properties of the regional myocardium by nifedipine in patients with coronary artery disease. (fiercecert.com)
  • 11. Sasayama S, Asanoi H, Kameyama T, Nonogi H , Kawai C: The mechanism of improvement of pacing-induced ischemia by nifedipine in patients with coronary artery disease. (fiercecert.com)
  • 14. Nonogi H , Sasayama S, Miyazaki S, Kawai C: An analysis of regional left ventricular function utilyzing pressure-length relationship in patients with coronary artery disease. (fiercecert.com)
  • 20. Nonogi H , Hess OM, Ritter M, Bortone AS, Corin WJ, Grimm J, Krayenbuhl: Prevention of coronary vasoconstriction by diltiazem during dynamic exercise in patients with coronary artery disease. (fiercecert.com)
  • Silent coronary artery disease in Japanese patients undergoing carotid artery stenting. (hyo-med.ac.jp)
  • Morphological characteristics of the atheromatous plaque have been associated with the development of plaque rupture and the pathogenesis of acute coronary syndromes (ACS). (ecrjournal.com)
  • Acute coronary syndromes (ACS) comprise a major cause of morbidity and mortality. (ecrjournal.com)
  • BACKGROUND: Detailed morphological characteristics of de novo and donor-transmitted plaques and the association of serum T-lymphocyte cytokine levels with plaque progression of coronary allograft vasculopathy within 1 year after heart transplantation are unknown. (bvsalud.org)
  • 1-3 Plaque rupture, the most frequent mechanism of coronary thrombosis, involves disruption of a thin fibrous cap that overlies a large necrotic core, causing the thrombogenic contents of the necrotic core to come into contact with the bloodstream and trigger thrombus formation. (ecrjournal.com)
  • Since the introduction of selective coronary angiography and percutaneous coronary angioplasty, imaging has become increasingly important in the diagnosis and management of heart disease. (medscape.com)
  • Equal in importance to defining the role of thrombolytic therapy is the choice between routine early angiography, followed by revascularization with either percutaneous transluminal coronary angioplasty (PTCA)12, 13 or coronary artery bypass grafting (CABG)14, 15, and angiography performed only when ischemia is persistent or readily provokable. (nih.gov)
  • From the OCT databases of 4 institutions, we identified 31 patients with ST-segment elevation myocardial infarction who underwent coronary angiography within 12 h after the onset of symptoms with the intent to perform a primary percutaneous coronary intervention with thrombus aspiration. (cardiolefrog.fr)
  • Such patients have a high incidence of thrombotic coronary artery occlusion1, and the early intravenous administration of thrombolytic agents has been shown to reestablish perfusion, limit the extent of left ventricular dysfunction18-20, and reduce both early (in-hospital)21 and late (1-year) mortality22, 23 in this group. (nih.gov)
  • In autopsy studies, at least 25% of thrombotic coronary occlusions are caused by plaque erosion in which thrombus often overlies atherosclerotic plaque without evident disruption of the fibrous cap. (cardiolefrog.fr)
  • The advent of multislice computed tomography (CT) angiography with high-resolution images obtained in seconds has completely revolutionized the way we look at, diagnose, and attempt to treat cardiovascular diseases. (medscape.com)
  • Cardiac CT is rapidly gaining its place in the emergency room and chest pain units for the diagnosis of the 3 main causes of chest pain: coronary heart disease, aortic dissection, and pulmonary embolism . (medscape.com)
  • García-Vázquez V, Matysiak F, Jäckle S, Eixmann T, Sieren MM, von Haxthausen F, Ernst F (2020) Catheter pose-dependent virtual angioscopy images for endovascular aortic repair: validation with a video graphics array (VGA) camera. (fraunhofer.de)
  • Since coronary thrombosis is now recognized to be present and of etiologic importance in many cases of unstable angina as well9-11, a test of the hypothesis that thrombolysis will also be of value in this group is timely and appropriate. (nih.gov)
  • The widespread use of 16 and, more recently, 64-slice cardiac CT has shortened acquisition time and significantly improved temporal and spatial resolution, providing high-quality images of the heart and coronary vessels. (medscape.com)
  • Intravascular ultrasound (IVUS), one of the initial intravascular tools for precise coronary imaging, has morphed into more complex systems that can produce accurate, almost histologic images of the plaque (virtual histology). (medscape.com)