Pulmonary EmbolismThromboembolismSinus thrombosisCerebral venousComplicationCentral venous thrombosisSymptomsArterial and venousThrombiObstructionInfarctionBilateralEmbolismThrombusUncommonIncidenceMTHFR C677TRecurrent thrombosisEpidemiologyUpper extremityVenographyAnticoagulationVeinVena cavaClinicalHeparinCoronavirus DiseaseVeinsRiskMorbidityBloodOccursThrombocytopeniaPatientsPreventionSecondaryProthrombinDiseaseVenogram
Pulmonary Embolism17
- Venous thromboembolism (VTE, including deep vein thrombosis [DVT] and pulmonary embolism [PE]) in surgical patients undergoing general anesthesia has been extensively studied. (medscape.com)
- For more information, see Deep Venous Thrombosis and Pulmonary Embolism . (medscape.com)
- Apart from IDA, other hematologic abnormalities seen in patients with CD are thrombocytosis, splenic hypofunction, leukopenia, IgA deficiency, enteropathy-associated T cell lymphoma (EATL), and rarely venous thromboembolism (VTE), including deep venous thrombosis (DVT) and pulmonary embolism (PE). (hindawi.com)
- Thrombolytic therapy offers significant advantages over conventional anticoagulant therapy, including the prompt resolution of symptoms, the prevention of pulmonary embolism, the restoration of normal venous circulation, the preservation of venous valvular function, and the prevention of postthrombotic syndrome. (medscape.com)
- Venous thrombosis and pulmonary embolism occur frequently. (hellosites.net)
- Thrombosis legs can cause pulmonary embolism, a life-threatening condition. (hellosites.net)
- There may be a life threatening complication called deep venous thrombosis (DVT) or pulmonary embolism (PE) as a result. (news-medical.net)
- Studies of the risks of deep vein thrombosis (DVT) and pulmonary embolism (PE) in patients with Sjögren syndrome (SS) in Asia are scant. (jrheum.org)
- Venous thromboembolism (VTE) includes deep vein thrombosis (DVT) and pulmonary embolism (PE). (jrheum.org)
- Deep venous thrombosis (DVT) and pulmonary embolism (PE) are manifestations of a single disease entity, namely, venous thromboembolism (VTE). (medscape.com)
- Many patients were treated for VTE on an outpatient basis, and secondary prevention of VTE was typically continued for 3 to 6 months after an episode of deep vein thrombosis or for longer in the case of pulmonary embolism. (nus.edu.sg)
- They often happen in your legs (called deep venous thrombosis or DVT ), in your lungs (called pulmonary embolism or PE), and sometimes in your brain ( stroke ). (webmd.com)
- This could be a blood clot in the leg (called deep vein thrombosis) or a clot that can break off and travel to the lung (called a pulmonary embolism). (nih.gov)
- The relationships between the Arterial and venous thrombosis, which clinical presentation and FVII levels and the clinically manifest as stroke, myocardial in- associated molecular genetic defects lack farction or pulmonary embolism are a ma- apparent consistency [ 7,10 ]. (who.int)
- Genetic polymorphisms in venous thrombosis and pulmonary embolism after total hip arthroplasty: a pilot study. (cdc.gov)
- Deep vein thrombosis (DVT) and pulmonary embolism (PE) are two manifestations of venous thromboembolism (VTE), an underdiagnosed, serious, and sometimes-preventable medical condition that occurs when a blood clot forms in a deep vein (DVT) and subsequently breaks up and travels to the lungs (PE). (cdc.gov)
- Venous thromboembolism (VTE) including deep vein thrombosis (DVT) and pulmonary embolism (PE) is commonly encountered in daily clinical practice. (bvsalud.org)
Thromboembolism17
- Venous thromboembolism (VTE) as a presentation of celiac disease is unusual and rarely reported. (hindawi.com)
- He denied a previous history of malignancy or venous thromboembolism. (hindawi.com)
- Severe novel coronavirus pneumonia (NCP) patients have abnormal blood coagulation function, but their venous thromboembolism (VTE) prevalence is still rarely mentioned. (scienceopen.com)
- Deep venous thrombosis (DVT) is a manifestation of venous thromboembolism (VTE). (medscape.com)
- Venous thromboembolism (VTE) is a common complication in cancer patients and a significant cause of morbidity and mortality. (nus.edu.sg)
- The incidence rates for recurrent venous thromboembolism (VTE), major bleeding, and mortality were 5.3, 4.4, and 13.0 per 100 patient-years, respectively. (universimed.com)
- Numerous case reports and retrospective chart reviews have reported incidences of thromboses in hospitalized COVID-19 patients, ranging from 2 to 79% for venous thromboses or thromboembolism (VT/VTE) [ 5 - 25 ] and 1.4 to 3.6% for arterial thromboses and embolic events (AT/ATE) [ 5 , 17 , 18 , 20 , 26 , 27 ]. (plos.org)
- 2006) Extrinsic Venous Compression: A Sufficient Explanation for Venous Thromboembolism Due to Massive Fibroids? (scirp.org)
- Some people who have sickle cell disease are at greater risk for developing abnormal blood clots (venous thromboembolism). (nih.gov)
- This study will look at the blood of people who have sickle cell disease and venous thromboembolism, as well as healthy volunteers, to help researchers develop better treatments to prevent blood clots. (nih.gov)
- Cancer and its treatments are well-known risk factors for venous thromboembolism (VTE). (oncologynurseadvisor.com)
- Venous thromboembolism (VTE) is a common complication in patients with malignant disease. (oncologynurseadvisor.com)
- Currently, cancer and its treatments are well-recognized risk factors for venous thromboembolism (VTE). (oncologynurseadvisor.com)
- Genetic variations observed in arterial and venous thromboembolism--relevance for therapy, risk prevention and prognosis. (cdc.gov)
- A preliminary study of inherited thrombophilic risk factors in different clinical manifestations of venous thromboembolism in central Iran. (cdc.gov)
- Venous thromboembolism (VTE) acquired during hospitalization is common, yet preventable by the proper implementation of thromboprophylaxis which remains to be underutilized worldwide. (bvsalud.org)
- BACKGROUND AND OBJECTIVES: Venous thromboembolism (VTE) is commonly encountered in the daily clinical practice. (bvsalud.org)
Sinus thrombosis19
- Cerebral venous sinus thrombosis (CVST), cerebral venous and sinus thrombosis or cerebral venous thrombosis (CVT), is the presence of a blood clot in the dural venous sinuses (which drain blood from the brain), the cerebral veins, or both. (wikipedia.org)
- 40% of people have seizures, although it is more common in women who develop sinus thrombosis peripartum (in the period before and after giving birth). (wikipedia.org)
- Cerebral venous sinus thrombosis is more common in particular situations. (wikipedia.org)
- There are various neuroimaging investigations that may detect cerebral sinus thrombosis. (wikipedia.org)
- For example, cerebral infarction may occur with cortical vein or sagittal sinus thrombosis secondary to tissue congestion with obstruction. (medscape.com)
- Lateral sinus thrombosis may be associated with headache and a pseudotumor cerebri-like picture. (medscape.com)
- Extension into the jugular bulb may cause jugular foramen syndrome, while cranial nerve palsies may be seen in cavernous sinus thrombosis as a compressive phenomenon. (medscape.com)
- Cerebral hemorrhage also may be a presenting feature in patients with venous sinus thrombosis. (medscape.com)
- Imaging procedures have led to easier recognition of venous sinus thrombosis (see the images below), offering the opportunity for early therapeutic measures. (medscape.com)
- Left lateral sinus thrombosis demonstrated on magnetic resonance venography (MRV). (medscape.com)
- US Case Reports of Cerebral Venous Sinus Thrombosis with Thrombocytopenia after Ad26.COV2.S Vaccination, March 2 to April 21, 2021. (eso-stroke.org)
- Use of oral contraceptive pills (OCP) increases the risk of cerebral venous sinus thrombosis (CVST). (frontiersin.org)
- Cerebral venous sinus thrombosis (CVST) is a form of stroke whereby thrombosis occurs in the cerebral venous sinuses or veins. (frontiersin.org)
- Several of the slides later in the presentation will refer to cerebral venous sinus thrombosis or CVST. (cdc.gov)
- We report the first case of COVID-19 presenting with generalized seizure secondary to cerebral venous sinus thrombosis. (scienceopen.com)
- Cerebral Venous Sinus Thrombosis Associated with Coronavirus Disease 2" by Kessarin Panichpisal, Ilana Ruff et al. (marquette.edu)
- We present a case report of a patient with cerebral venous sinus thrombosis (CVST) associated with COVID-19 and performed a literature review of CVST associated with COVID-19 cases. (marquette.edu)
- Magnetic resonance imaging brain showed diffuse venous sinus thrombosis involving the superficial and deep veins, and diffuse edema of bilateral thalami, basal ganglia and hippocampi because of venous infarction. (marquette.edu)
- Use was paused during April 12-23, 2021, after detection of six cases of cerebral venous sinus thrombosis (CVST). (cdc.gov)
Cerebral venous8
- Knowledge of the anatomy of the venous system is essential in evaluating patients with cerebral venous thrombosis (CVT), since symptoms associated with the condition are related to the area of thrombosis. (medscape.com)
- Many causative conditions have been described in cerebral venous thrombosis (CVT). (medscape.com)
- Cerebral venous thrombosis (CVT) is a less common type of stroke, happening approximately in 1.5:100'000 adults 1 . (eso-stroke.org)
- The Incidence of Cerebral Venous Thrombosis. (eso-stroke.org)
- Cerebral venous thrombosis and severe acute respiratory syndrome coronavirus-2 infection: A systematic review and meta-analysis. (eso-stroke.org)
- Almost 40% had deep cerebral venous system thrombosis. (marquette.edu)
- Cerebral venous thrombosis (CVT) is a relatively rare condition that results from thrombosis of the superficial or deep venous sinuses of the brain. (aku.edu)
- Cerebral venous thrombosis (CVT) is an unusual cause of stroke. (citefactor.org)
Complication4
- Venous thrombosis is a common complication in patients with cancer, leading to additional morbidity and compromising quality of life. (nih.gov)
- We report a life-threatening specific complication of influenza A(H1N1)pdm09 infection that was responsible for lethal central venous thrombosis. (cdc.gov)
- Khilanani, R. and Dandolu, V. (2007) Extensive Iliac Vein Thrombosis as a Rare Complication of a Uterine Leiomyoma: A Case Report. (scirp.org)
- Superficial venous thrombosis (SVT) of lower extremities is a common complication of VV. (bvsalud.org)
Central venous thrombosis1
- In children, head and neck infections and acute systemic illnesses are the primary cause of central venous thrombosis. (wikipedia.org)
Symptoms7
- Common symptoms in the elderly with this condition are otherwise unexplained changes in mental status and a depressed level of consciousness. (wikipedia.org)
- The goals of endovascular therapy include reducing the severity and duration of lower-extremity symptoms, preventing PE, diminishing the risk of recurrent venous thrombosis, and preventing postthrombotic syndrome (PTS). (medscape.com)
- The symptoms of thrombosis depend in part on where in the body the thrombosis occurs. (hellosites.net)
- He rapidly died after unusual symptoms related to intracerebral thrombosis and hemorrhage. (cdc.gov)
- [ 2 ] and as many as 50% of those with image-documented venous thrombosis lack specific symptoms. (medscape.com)
- In addition to VTE, arterial occlusion with stroke and anginal symptoms is relatively common among cancer patients, and is possibly related to genetic predisposition. (oncologynurseadvisor.com)
- A clinical picture composed of fragments of the syndrome or of the hemisection syndrome plus additional symptoms and signs is more common. (medscape.com)
Arterial and venous2
- After heparin exposure, heparin-induced thrombocytopenia (HIT) can develop, with a concrete risk of developing thrombosis at both arterial and venous sites 4,6 . (eso-stroke.org)
- Arterial and venous thrombosis were both common occurrences among patients with COVID-19 infection. (plos.org)
Thrombi1
- This finding may lead to a false sense of security because although the total number of deep venous thrombi may be similar to the numbers observed with pharmacologic prophylaxis, the proportion of the relatively more dangerous proximal clots is increased (see Table 1 below). (medscape.com)
Obstruction3
- The diagnosis is usually by computed tomography (CT scan) or magnetic resonance imaging (MRI) to demonstrate obstruction of the venous sinuses. (wikipedia.org)
- arterial infarction can be due to either obstruction from thrombosis or embolism or to occlusion from blood vessel abnormalities such as vasculitis. (vin.com)
- 2006) Large Uterine Fibroids Causing Mechanical Obstruction of the Inferior Vena Cava and Subsequent Thrombosis: A Case Report. (scirp.org)
Infarction3
- Cerebral edema and venous infarction may be apparent on any modality, but for the detection of the thrombus itself, the most commonly used tests are computed tomography (CT) and magnetic resonance imaging (MRI), both using various types of radiocontrast to perform a venogram and visualise the veins around the brain. (wikipedia.org)
- Thrombosis of the venous channels in the brain is an uncommon cause of cerebral infarction relative to arterial disease, but it is an important consideration because of its potential morbidity. (medscape.com)
- Thrombosis occurs in the arteries and can cause myocardial or cerebral infarction . (hellosites.net)
Bilateral4
- We present a case of a 46-year-old man who was admitted for shortness of breath and pleuritic chest pain and was found to have iron deficiency anemia, deep venous thrombosis, and bilateral pulmonary emboli (PE). (hindawi.com)
- A cranial computed tomographic (CT) scan showed thrombosis of the superior sagittal sinus associated with 3 cerebral hematomas (left frontal and bilateral parieto-occipital) and diffuse cerebral edema with signs of increased intracranial pressure ( Figure ). (cdc.gov)
- CT venography showing bilateral deep venous thrombosis. (medscape.com)
- Arrows indicate bilateral deep venous thrombosis. (medscape.com)
Embolism1
- With thrombocytopenia and abnormal bleeding there may also be another problem of increased blood clotting or embolism or thrombosis. (news-medical.net)
Thrombus3
- Percutaneous transcatheter treatment of patients with deep venous thrombosis (DVT) consists of thrombus removal with catheter-directed thrombolysis, mechanical thrombectomy, angioplasty, and/or stenting of venous obstructions. (medscape.com)
- Thrombosis of the superior sagittal sinus was caused by a platelet-fibrin thrombus. (cdc.gov)
- Presence of an obstructing blood clot ( thrombus ) is referred to as thrombosis. (medbroadcast.com)
Uncommon1
- Examples of this type of situation can be when CVT develops as part of an autoimmune-mediated thrombocytopenia, as for heparin-induced thrombocytopenia (HIT) 4 or as part of a vaccine-induced thrombocytopenia (VITT), with thrombosis happening also at other uncommon sites 3,5 . (eso-stroke.org)
Incidence3
- The incidence of symptomatic deep vein thrombosis (7 of 10,000 deliveries) shown prospectively by ultrasonography was similar to that of historic controls who had a diagnosis confirmed by venography (11 of 26,191 deliveries). (qxmd.com)
- Leur incidence en Afrique sub-saharienne et plus particulièrement au Gabon est mal connue. (bvsalud.org)
- BACKGROUND: Cervical cancer is the third most common gynecological malignancy in Saudi women with an estimated incidence rate of 1.9 cases per 100 000 women-years. (bvsalud.org)
MTHFR C677T1
- Prevalence of factor V Leiden, FII G20210A, FXIII Val34Leu and MTHFR C677T polymorphisms in cancer patients with and without venous thrombosis. (cdc.gov)
Recurrent thrombosis2
- Cancer is a risk factor for DVT, particularly in older patients and in patients with recurrent thrombosis. (merckmanuals.com)
- Continuation of therapy beyond that should be based on the risk for recurrent thrombosis versus the risk of major bleeding for each individual patient. (oncologynurseadvisor.com)
Epidemiology1
- This review will focus on the epidemiology and pathophysiology of cancer-associated thrombosis, risk factors, and new predictive biomarkers for VTE as well as discuss novel prevention and management regimens of VTE in cancer according to published guidelines. (oncologynurseadvisor.com)
Upper extremity1
- or occur during strenuous arm activity (effort thrombosis, or Paget-Schroetter syndrome, which accounts for 1 to 4% of upper extremity DVT cases). (merckmanuals.com)
Venography3
- Computed tomography, with radiocontrast in the venous phase (CT venography or CTV), has a detection rate that in some regards exceeds that of MRI. (wikipedia.org)
- A preferential pattern of proximal left-sided iliac or femoral vein involvement was common to both cohorts, being seen in five of the seven cases diagnosed by ultrasonography and eight of the eleven cases diagnosed by venography. (qxmd.com)
- We conclude that ultrasonography, consisting of compression ultrasonography and color flow imaging, can replace venography in the diagnosis and evaluation of the extent of symptomatic deep vein thrombosis during pregnancy. (qxmd.com)
Anticoagulation2
- For the treatment of VTE, LMWH was again the most common initial treatment, although, for the long-term, oral anticoagulation therapy was widely adopted. (nus.edu.sg)
- Several studies have shown high rates of thrombosis despite anticoagulation [ 9 - 11 , 14 - 16 , 18 - 20 , 25 ]. (plos.org)
Vein8
- Thrombocytopenia can be severe, and thrombosis can happen at unusual sites, including the splanchnic vein. (eso-stroke.org)
- Deep venous thrombosis (DVT) is clotting of blood in a deep vein of an extremity (usually calf or thigh) or the pelvis. (merckmanuals.com)
- Color flow imaging combined with compression ultrasonography were used to prospectively evaluate symptomatic patients first seen with suspected deep vein thrombosis during pregnancy. (qxmd.com)
- Anticoagulant therapy for splanchnic vein thrombosis: An individual patient data meta-analysis. (universimed.com)
- Thrombosis in a vein is almost always associated with phlebitis (inflammation of a vein). (medbroadcast.com)
- One common cause is due to trauma or injury, for example from solutions or medications given intravenously (into a vein) in hospitals. (medbroadcast.com)
- Deep venous thrombosis is a blood clot that forms in a vein deep inside a part of the body. (umms.org)
- Hyperhomocysteinemia and C677T MTHFR genotype in patients with retinal vein thrombosis. (cdc.gov)
Vena cava1
Clinical3
- We demonstrate this increased risk of blood clots by comparing rates of venous and arterial clotting events in 4400 hospitalized COVID-19 patients in a large multisite clinical network in the United States examined from April through June of 2020, to patients hospitalized for non-COVID illness and influenza during the same time period and in 2019. (plos.org)
- The triad of hemolytic anemia, pancytopenia, and thrombosis makes PNH a unique clinical syndrome. (medscape.com)
- Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2010 Oct 16 (5): 549-53. (cdc.gov)
Heparin1
- Early prophylaxis in surgical patients with low-molecular-weight heparin (LMWH) has been associated with significant reductions in postoperative venous thrombosis. (medscape.com)
Coronavirus Disease1
- Coronavirus disease 2019 (COVID-19) is associated with significant risk of acute thrombosis. (marquette.edu)
Veins7
- This is a somewhat rare type of thrombosis involving large veins inside the head such as those shown on this diagram. (cdc.gov)
- In other words, thrombosis can affect either superficial (surface) or deep (below the surface) veins, causing thrombophlebitis. (medbroadcast.com)
- Deep venous thrombosis (DVT) occurs when a blood clot affects deeper, larger veins, such as those in the lower legs and thighs. (medbroadcast.com)
- Comparison of day surgery between varicose veins with and without superficial venous thrombosis below knee: a propensity score-matched analysis. (bvsalud.org)
- 4 ]. In Eastern Mediterranean countries, the involving the entire length of the common highest frequency of factor V Leiden was femoral, popliteal and calf veins extend- reported in Lebanon (14%) [ 5,6 ]. (who.int)
- However, ing into the left external iliac and common there are no studies related to awareness of iliac veins. (who.int)
- Superficial venous thrombosis: prevalence of common genetic risk factors and their role on spreading to deep veins. (cdc.gov)
Risk13
- Disorders that cause, or increase the risk for systemic venous thrombosis are associated with central venous thromboses. (wikipedia.org)
- Risk of venous thrombosis. (nih.gov)
- Patients with cancer have a highly increased risk of venous thrombosis especially in the first few months after diagnosis and in the presence of distant metastases. (nih.gov)
- Factors that increase the risk of developing thrombosis are different for arterial thrombosis and venous thrombosis. (hellosites.net)
- Venous thrombosis is a multifactorial disease frequently related to the interaction of genetic and environmental risk factors. (intechopen.com)
- Some of the recently discovered genetic risk factors, such as factor V Leiden and prothrombin G20210A mutations, are quite common in the population. (intechopen.com)
- Prevalence and risk of individual thrombophilic markers with a time line representing their discovery[ 1 ] Despite the expansion of these methods, the following years brought forth discoveries of defects on a molecular basis, which posed decreasing risks of thrombosis, as can be seen in Fig 1 . (intechopen.com)
- Brain and pancreatic tumors were considered to carry a high risk for VTE, and 80% of respondents considered the use of central venous lines to be associated with a high risk of VTE. (nus.edu.sg)
- We demonstrate that COVID-19 increases the risk of venous thrombosis by two-fold compared to the general inpatient population and compared to people with influenza infection. (plos.org)
- Risk factors for thrombosis included male gender, older age, and diabetes. (plos.org)
- Several risk factors for developing venous thrombosis usually coexist in cancer patients including surgery, hospital admissions and immobilization, the presence of an indwelling central catheter, chemotherapy, use of erythropoiesis-stimulating agents (ESAs) and new molecular-targeted therapies such as antiangiogenic agents. (oncologynurseadvisor.com)
- Factor V Leiden is the most common in- are: factor V G1691A, factor II G20210A herited risk factor for venous thrombosis. (who.int)
- The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) study. (cdc.gov)
Morbidity2
- While much regarding the pathophysiology of this novel illness remains unknown, a growing body of evidence suggests that infection with SARS-CoV-2 precipitates a coagulopathy and that thromboses-both venous and arterial-contribute to morbidity and mortality [ 2 - 4 ]. (plos.org)
- Emerging data have enhanced our understanding of cancer-associated thrombosis, a major cause of morbidity and mortality in patients with cancer. (oncologynurseadvisor.com)
Blood7
- IPC devices are designed to decrease venous stasis, improve blood flow velocity, and increase the level of circulating fibrinolysins. (medscape.com)
- In thrombosis, a blood vessel becomes blocked by a blood clot. (hellosites.net)
- And inflammation of blood vessel walls causes blood clotting function, which leads to thrombosis. (hellosites.net)
- Thrombosis occurs when a blood clot blocks a blood vessel in the leg. (hellosites.net)
- Thrombosis is handled by removing the throm-bus in the shortest possible time, thus allowing restoration of the blood flow. (embj.org)
- Blood clots are more common in people with lupus. (webmd.com)
- In this population, blood clotting is the most common cause of vascular death after heart attack and stroke. (nih.gov)
Occurs1
- Celiac disease (CD), or gluten sensitive enteropathy, is a common, systemic autoimmune disease that occurs in genetically predisposed individuals secondary to exposure to dietary protein gluten and requires lifelong dietary treatment [ 1 ]. (hindawi.com)
Thrombocytopenia2
- The thrombosis with thrombocytopenia syndrome, or TTS, is a new syndrome that's been recognized to occur after receiving adenoviral vector COVID-19 vaccines. (cdc.gov)
- As the name suggests, this syndrome is characterized clinically by thrombosis and thrombocytopenia. (cdc.gov)
Patients4
- Hematologic abnormalities are frequently found in CD patients, with iron deficiency anemia (IDA) being the most common. (hindawi.com)
- Two patients developed venous thrombosis and two had gastrointestinal perforation. (medpagetoday.com)
- Patients with venous or arterial thrombosis had high rates of admission to the ICU, re-admission to the hospital, and death. (plos.org)
- Il s'agit d'une étude rétrospective descriptive et analytique, multicentrique portant sur des patients de moins de 5ans pris en charge pour une affection neurochirurgicale de Janvier 2019 à Décembre 2021 à Libreville. (bvsalud.org)
Prevention1
- Tracking Translation of Human Genome Discoveries into Prevention and Control of Common Chronic Diseases: The Action is in Cancer! (cdc.gov)
Secondary2
- Objectives: We present eight cases of vascular thrombosis of the pelvic vessels and deep venous thrombosis (DVT) of the lower limb, secondary to compression of the pelvic vessels by the uterine fibroid, managed over a span of twelve years from 2001 to 2013. (scirp.org)
- Conclusions: Uterine leiomyoma can cause vascular thrombosis secondary to compression of the pelvic vessels. (scirp.org)
Prothrombin1
- A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. (medscape.com)
Disease1
- The common denominator in the disease, a biochemical defect, appears to be a genetic mutation leading to the inability to synthesize the glycosyl-phosphatidylinositol (GPI) anchor that binds these proteins to cell membranes. (medscape.com)
Venogram1
- A venogram in July 1993 indicated deep venous thrombosis, which did not respond to standard therapy. (cdc.gov)