Loading...
  • epithelial
  • The pathological study showed malignant epithelial neoplasm which is composed of glands of irregular shapes, anastomosing with cribriform (Figure 2 ) and papillary (Figure 3 ) arrangements whose cells have a cylindrical shape with a high ratio nucleus/cytoplasm, hyperchromatic nuclei, with evident nucleoli, frequent mitotic figures, and vacuolated cytoplasm. (hindawi.com)
  • diagnosis
  • This chapter provides an extended, updated biological status of TRP2/L-DCT encompassing the structural and functional particularities within melanoma molecularity, in the attempt to get new insights into the complex mechanisms of this neoplasm and raise the interest for DCT unexplored yet potential in melanoma diagnosis/prognosis and therapy. (intechopen.com)
  • human
  • The most common mutation in human CMM BRAF (V600E) activates the serine/threonine kinase BRAF and causes excessive activity in the mitogen-activated protein kinase (MAPK) pathway [ 6 ]. (hindawi.com)
  • prognosis
  • In spite of the poor prognosis, surgical treatment followed by chemotherapy or radiotherapy or both is the most widely accepted option, given the aggressiveness of such neoplasms [ 4 ]. (hindawi.com)
  • terms
  • This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. (peerj.com)
  • This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License ( http://creativecommons.org/licenses/by-nc-sa/3.0/ ), which allows others to remix, tweak and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. (parjournal.net)