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  • tumors
  • To some extent, the symptoms depend upon the location of the tumor: patients with cholangiocarcinoma in the extrahepatic bile ducts (outside the liver) are more likely to have jaundice, while those with tumors of the bile ducts within the liver more often have pain without jaundice. (wikipedia.org)
  • Rarely there can be a metastatic neoplasm with no known site of the primary cancer and this is classed as a cancer of unknown primary origin Neoplastic tumors are often heterogeneous and contain more than one type of cell, but their initiation and continued growth is usually dependent on a single population of neoplastic cells. (wikipedia.org)
  • urinary bladder
  • Sarcoma botryoides or botryoid sarcoma or botryoid rhabdomyosarcoma is a subtype of embryonal rhabdomyosarcoma, that can be observed in the walls of hollow, mucosa lined structures such as the nasopharynx, common bile duct, urinary bladder of infants and young children or the vagina in females, typically younger than age 8. (wikipedia.org)
  • epigenetic
  • Neoplasms are mosaics of different mutant cells with both genetic and epigenetic changes that distinguish them from normal cells. (wikipedia.org)
  • While many of the genetic and epigenetic abnormalities in neoplasms are probably neutral evolution, many have been shown to increase the proliferation of the mutant cells, or decrease their rate of death (apoptosis). (wikipedia.org)
  • cancerous
  • Secondary neoplasm refers to any of a class of cancerous tumor that is either a metastatic offshoot of a primary tumor, or an apparently unrelated tumor that increases in frequency following certain cancer treatments such as chemotherapy or radiotherapy. (wikipedia.org)
  • cancer
  • For example, the most common type of breast cancer is called ductal carcinoma of the breast. (wikipedia.org)
  • Here, the adjective ductal refers to the appearance of the cancer under the microscope, which suggests that it has originated in the milk ducts. (wikipedia.org)
  • Cancer which has spread from elsewhere to the liver, known as liver metastasis, is more common than that which starts in the liver. (wikipedia.org)
  • Higher rates of liver cancer occur where hepatitis B and C are common, including Asia and sub-Saharan Africa. (wikipedia.org)
  • Liver cancer can also form from other structures within the liver such as the bile duct, blood vessels and immune cells. (wikipedia.org)
  • liver
  • More than 900 drugs have been implicated in causing liver injury (see LiverTox, external link, below) and it is the most common reason for a drug to be withdrawn from the market. (wikipedia.org)
  • Acetaminophen (in the US and Japan), paracetamol (INN), also known by the brand name Tylenol and Panadol, is usually well tolerated in prescribed dose, but overdose is the most common cause of drug-induced liver disease and acute liver failure worldwide. (wikipedia.org)
  • include
  • The most common include CT scan (computerized axial tomography), magnetic resonance imaging (MRI), positron emission tomography (PET), endoscopic ultrasound (EUS), and endoscopic retrograde pancreatography (ERCP). (wikipedia.org)
  • cause
  • Not all types of neoplasms cause a tumorous overgrowth of tissue, however (such as leukemia or carcinoma in situ). (wikipedia.org)
  • Hyperthyroidism occurs when the gland produces excessive amounts of thyroid hormones, the most common cause being Graves' disease - an autoimmune disorder. (wikipedia.org)
  • Worldwide, the most common cause is iodine deficiency. (wikipedia.org)
  • In iodine-sufficient regions, the most common cause of hypothyroidism is Hashimoto's thyroiditis-also an autoimmune disease. (wikipedia.org)
  • mainly
  • Both groups occur mainly (but not exclusively) in people over 40, and are slightly more common in men, but some rare sub-types mainly occur in women or children. (wikipedia.org)
  • It absorbs mainly vitamin B12 and bile acids, as well as any other remaining nutrients. (wikipedia.org)
  • Leukemia
  • For lymphoid neoplasms, e.g. lymphoma and leukemia, clonality is proven by the amplification of a single rearrangement of their immunoglobulin gene (for B cell lesions) or T cell receptor gene (for T cell lesions). (wikipedia.org)
  • Advances in cytogenetics facilitated discovery of chromosome abnormalities in neoplasms, including the Philadelphia chromosome in chronic myelogenous leukemia and translocations in acute myeloblastic leukemia. (wikipedia.org)
  • disease
  • In the Western world, the most common of these is primary sclerosing cholangitis (PSC), an inflammatory disease of the bile ducts which is closely associated with ulcerative colitis (UC). (wikipedia.org)
  • endoscopic
  • The most common include CT scan (computerized axial tomography), magnetic resonance imaging (MRI), positron emission tomography (PET), endoscopic ultrasound (EUS), and endoscopic retrograde pancreatography (ERCP). (wikipedia.org)
  • Adenocarcinoma
  • For example, neoplasms characterized by high-grade features, invasive glands and or signet ring cells, are termed adenocarcinoma in pathology literature. (wikipedia.org)
  • occur
  • Both groups occur mainly (but not exclusively) in people over 40, and are slightly more common in men, but some rare sub-types mainly occur in women or children. (wikipedia.org)