TACEHepatocellular CarcinomaRadiofrequencyAblationEmbolizationRadioembolizationTrans-arterial chemoembolizationTumorTherapiesResectionSystemicPalliative treatmentTherapySurvivalMetastasesLiver tumorsEffectivenessEvaluatePatientsPartialResponseCancerStandard treatmentAdditionProceduresPredictResultsStudy
TACE31
- Background To determine the safety and efficacy of transarterial chemoembolization (TACE) combined with radiofrequency ablation (hereafter, TACE-RFA) in treating Barcelona Clinic Liver Cancer (BCLC) Stage A or B (hereafter, BCLC A/B) hepatocellular carcinoma (HCC) patients, and to explore the range of tumor sizes suitable for combination therapy. (researchsquare.com)
- In recent years, transarterial chemoembolization (TACE) as a palliative therapy has been recognized as the standard method for patients with unresectable HCC [11,12]. (researchsquare.com)
- TACE can improve survival by combining targeted chemotherapy with ischemic necrosis caused by arterial embolization [12,13]. (researchsquare.com)
- We retrospectively evaluated the long-term effects of partial splenic embolization (PSE) with transarterial chemoembolization (TACE) in patients with HCC patients accompanied by thrombocytopenia. (hindawi.com)
- Since cirrhotic patients with severe thrombocytopenia are at greater risk for bleeding, treatments against HCC such as liver transplantation, resection, local ablation therapy, and transarterial chemoembolization (TACE) can be performed following a platelet transfusion in those patients. (hindawi.com)
- To evaluate the effectiveness of transarterial chemoembolization (TACE) combined with lenvatinib and sintilimab in treating patients with midstage hepatocellular carcinoma (HCC). (hindawi.com)
- According to different treatment regimens, they were divided into the control group (31 cases, TACE group) and the observation group (31 cases, TACE combined with lenvatinib and sintilimab group). (hindawi.com)
- TACE combined with lenvatinib and sintilimab in the treatment of Barcelona Clinic Liver Cancer (BCLC) stage B hepatocellular carcinoma can effectively control the tumor progression and prolong the survival time of patients. (hindawi.com)
- At present, both the European Association for the Study of the Liver (EASL) [ 2 ] and the American Association for the Study of Liver Diseases (AASLD) [ 3 ] recommend transarterial chemoembolization (TACE) as the standard treatment option for patients with intermediate-stage (BCLC stage B) HCC. (hindawi.com)
- However, to date, TACE combined with lenvatinib plus sintilimab has not been studied for patients with BCLC B-stage HCC. (hindawi.com)
- Therefore, we conducted this retrospective study to assess the efficacy and safety of TACE combined with lenvatinib plus sintilimab in BCLC B-stage HCC. (hindawi.com)
- This preliminary study was aimed at evaluating the effectiveness of TACE combined with lenvatinib and sintilimab in treating patients with midstage HCC. (hindawi.com)
- Objective response rate and disease control rate for PVBTT were 58.9 and 91.2%, respectively, in the combined treatment group, which were significantly greater than the 5.7 and 54.3% rates, respectively, in the TACE-alone group (both p 's ≤ 0.001). (biomedcentral.com)
- Therefore, other therapeutic modalities to improve the survival of such patients are being tried, including surgical resection, transarterial chemoembolization (TACE), chemotherapy, and three-dimensional conformal radiotherapy, but the clinical outcomes remain unsatisfactory. (biomedcentral.com)
- AIM: To evaluate and compare the effect of combined transarterial chemoembolization (TACE) and arterial administration of Bletilla striata (a Chinese traditional medicine against liver tumor) versus TACE alone for the treatment of hepatocellular carcinoma (HCC) in ACI rats. (uni-frankfurt.de)
- Chemoembolization or TACE (transarterial chemoembolization) is a treatment modality that combines intraarterial chemotherapy with embolization and is now widely used in some types of cancer. (interventionaloncology.center)
- There are two different types of chemoembolization (TACE) application: 1. (interventionaloncology.center)
- The classical chemoembolization method, Lipiodol-TACE, was first developed in Japan in the 1980s. (interventionaloncology.center)
- DEB-TACE is derived from the initials of the English word 'Drug Eluting Beads' and is a new type of chemoembolization. (interventionaloncology.center)
- Transcatheter arterial chemoembolization (TACE) via the inferior phrenic artery has been recognized to have its own therapeutic role without causing serious procedural complications. (biomedcentral.com)
- Transcatheter arterial chemoembolization (TACE) is a standard locoregional treatment for intermediate-stage hepatocellular carcinoma (HCC) [ 1 ]. (biomedcentral.com)
- Transcatheter arterial chemoembolization (TACE) via the right inferior phrenic artery. (biomedcentral.com)
- Patients with more advanced disease are currently offered palliative treatment, including localized transarterial chemoembolization (TACE) or systemic chemotherapy. (biomedcentral.com)
- Combined SBRT and immunotherapy resulted in significantly superior survival and less toxicity compared with transcatheter arterial chemoembolization (TACE) [ 14 ]. (biomedcentral.com)
- Aim: The objective of this study was to analyze survival rates of Child-Pugh A and B patients with intermediate HCC tumors treated with transarterial chemoembolization (TACE) followed by full-dose sorafenib usage. (unesp.br)
- Conclusions: sorafenib after TACE can be an option for selected cirrhotic patients with intermediate HCC tumors if this combined approach is cautiously performed on an individualized schedule. (unesp.br)
- In intermediate stage HCC, according to the Barcelona Clinic Liver Cancer staging system (BCLC B) [ 4 ], with a multinodular affection transarterial chemoembolization (TACE) is the gold standard therapy to date. (biomedcentral.com)
- CT-guided 125I brachytherapy for hepatocellular carcinoma in high-risk locations after transarterial chemoembolization combined with microwave ablation: a propensity score-matched study: CT-guided 125I brachytherapy for HCC in high-risk locations after TACE combined with MWA: a propensity score-matched study. (radioloncol.com)
- Transarterial chemoembolisation (TACE) using irinotecan-eluting beads is an additional treatment option for colorectal cancer liver metastases (CRLM) patients that are not eligible for curative treatment approaches. (springer.com)
- Transarterial chemoembolisation (TACE) using irinotecan-eluting beads is part of the loco-regional treatments toolbox to control colorectal cancer liver metastases (CRLM) in the 80% of patients that are not eligible for the only proven curative treatment options, surgery and thermal ablation [ 1 , 2 ]. (springer.com)
- Such non-surgical procedures include radiofrequency ablation (RFA), microwave ablation (MWA), Trans arterial chemoembolization (TACE), Trans arterial radio embolization (TARE). (livertransplantsurgeon.co.in)
Hepatocellular Carcinoma5
- Lenvatinib Combined With Transarterial Chemoembolization as First-Line Treatment for Advanced Hepatocellular Carcinoma: A Phase III, Randomized Clinical Trial (LAUNCH). (nih.gov)
- Chemoembolization was first used in hepatocellular carcinoma (HCC), one of the primary cancers of the liver, has been highly successful and has entered the classical treatment guidelines years ago. (interventionaloncology.center)
- Comparable survival in patients with unresectable hepatocellular carcinoma treated by radiofrequency ablation battlefield 2042 no recoil scripts transarterial chemoembolization. (institutoomnes.es)
- Target lesion response predicts survival of patients with hepatocellular carcinoma retreated with transarterial chemoembolization. (medscape.com)
- Prediction of Early Treatment Response to Initial Conventional Transarterial Chemoembolization Therapy for Hepatocellular Carcinoma by Machine-Learning Model Based on Computed Tomography. (cdc.gov)
Radiofrequency3
- Combined radiofrequency ablation and PEI for the treatment of HCC. (aetna.com)
- Along with systemic therapy, liver-targeted therapies for recurrent HCC including, radiofrequency, microwave ablation, transarterial chemoembolization, and stereotactic body radiation therapy are promising options. (xiahepublishing.com)
- In addition, we are studying how ablative therapies including radiofrequency ablation, cryoablation, transarterial chemoembolization, and radiation can be combined with immune-based treatments in patients with hepatobiliary tumors and patients with colon cancer and liver metastasis. (nih.gov)
Ablation2
- We also offer non surgical option for liver tumors like radio-frequency ablation, trans-arterial chemoembolization, radioactive micro-sphere injections etc. (livertransplantsurgeon.co.in)
- It consists of 4 treatment options to improve patients' life quality - cryosurgical ablation (CSA) to destroy a tumor, microvascular interventional сhemotherapy (CMI) to kill remained cancerous cells, combined immunotherapy for cancer (CIC) to make the body fight with cancer itself, and personalized treatment. (bookimed.com)
Embolization4
- It is unclear whether chemotherapy, arte- rial embolization, or arterial chemoembolization improve survival advantage enough to justify their high toxicity. (pinestreetfoundation.org)
- Arterial embolization, chemoembolization, and arterial chemotherapy are the major procedures in chemotherapy. (pinestreetfoundation.org)
- Arterial embolization or chemoemboli- zation is a technique combining intra-arterial chemo- therapy and selective ischemia and was developed as an alternative to conventional systemic or intra-arterial chemotherapy. (pinestreetfoundation.org)
- Arterial embolization or chemoembolization includes procedures such as transcatheter arterial chemo- embolization, transarterial embolization, hepatic arterial chemoembolization, and hepatic arterial embolization. (pinestreetfoundation.org)
Radioembolization3
- Transarterial chemoembolization or radioembolization using Yttrium-90 can be used for patients with an incurable disease and have comparatively low adverse effects. (xiahepublishing.com)
- Since patients with NET usually survive for many years, chemoembolization can often be applied more than once in these patients, or it can be used in a specific order with other methods of treatment such as lutetium treatment or radioembolization. (interventionaloncology.center)
- Currently, both chemoembolization and radioembolization are widely used in the bile duct cancer of liver (cholangiocarcinoma). (interventionaloncology.center)
Trans-arterial chemoembolization1
- Drug-eluting beads trans-arterial chemoembolization for leiomyosarcoma, liver metastases from colorectal cancer, and for primary and liver-dominant metastatic disease of the liver. (aetna.com)
Tumor2
- Surgical resection includes cholecystectomy, en bloc hepatic resection (typically of segments IVb and V), and lymphadenectomy with or without bile duct excision, depending on the location of the tumor. (medscape.com)
- They retained those that (1) treated only HCC pa- tients, (2) were described as randomized or reported that there was no statistical difference between treatment groups, (3) gave patients either Chinese herbal medicine therapy combined with chemotherapy in the treatment group or chemotherapy alone in the control group, and (4) provided data on the number of enrolled subjects and re- sponders and nonresponders for tumor response and sur- vival. (pinestreetfoundation.org)
Therapies2
- In addition, RT, combined with transarterial chemoembolization or other locoregional therapies, can be used as a first-line treatment for patients with advanced HCC showing macroscopic vascular invasion for better progression-free and overall survival rates [ 9 , 10 ]. (e-cmh.org)
- Such procedure can be done alone for larger size liver tumors, and can also be combined with ablative therapies. (livertransplantsurgeon.co.in)
Resection1
- However, these can be combined along with liver resection, when lesions are multiple and scatterered in multiple lobes of the liver. (livertransplantsurgeon.co.in)
Systemic1
- New studies have shown promising results from combining locoregional and systemic treatments, but most of them were limited to Child-Pugh A patients due to toxicity concerns. (unesp.br)
Palliative treatment1
- Chemoembolization (CE) for other indications including palliative treatment of liver metastases from other non-neuroendocrine primaries (e.g., breast cancer, cervical cancer, colon cancer, esophageal cancer, melanoma, rhabdomyosarcoma, or unknown primaries) and CE of the pancreas for pancreatic cancer. (aetna.com)
Therapy2
- For this patient population, HIFU can offer the option to combine a low morbidity local therapy. (biomedcentral.com)
- In this initial experience, decision making during endovascular acute stroke intervention in the combined angiography-MRI suite was better informed at MRI, such that therapy was guided in real time by the viability of the at-risk cerebral tissue. (ircommune.com)
Survival2
- Some studies have shown that chemoembolization + classical chemotherapy may extend survival by two times more than classical chemotherapy alone. (interventionaloncology.center)
- Results: The mean survival was 379 days in the combined treatment group and 151 days in the single-treatment group (p = 0.007). (unesp.br)
Metastases3
- Following the good results obtained in the treatment of HCC, chemoembolization was also tried in liver metastases of different origin. (interventionaloncology.center)
- Another common area of chemoembolization is liver metastases of the large intestine. (interventionaloncology.center)
- In addition, chemoembolization has an important role in the rare vessel-rich tumors of the liver (hemangioperisitoma, hemangioblastoma, etc.) and other liver metastases (breast, kidney cancer, etc. (interventionaloncology.center)
Liver tumors1
- Chemoembolization has been used successfully in other liver tumors besides these common applications. (interventionaloncology.center)
Effectiveness1
- The au- thors sought to evaluate the effectiveness of Chinese herbal medicine combined with chemotherapy. (pinestreetfoundation.org)
Evaluate1
- Purpose To evaluate use of MRI to guide critical decision making by using a combined biplane x-ray neuroangiography 3.0-T MRI suite during acute ischemic stroke intervention. (ircommune.com)
Patients3
- After chemoembolization, the majority of patients present with abdominal pain, nausea, fatigue and fever (postembolization syndrome), which can last for 3-4 days. (interventionaloncology.center)
- 000). Conclusions: These findings provide promising evidence that combining Chinese herbal medicine with chemotherapy may benefit patients with HCC. (pinestreetfoundation.org)
- I am convinced that a combined effort using different antitumor approaches will result in the best possible outcome for our patients. (nih.gov)
Partial1
- Despite the methods' clinical potential, the liver is a particularly challenging organ for HIFU treatment due to the combined effect of respiratory-induced liver motion, partial blocking by the rib cage, and high perfusion/flow. (biomedcentral.com)
Response1
- Treatment with Chinese herbal medicine has been explored, combining herbs that stimulate host immune response with those that have cytotoxic activity against HCC cells. (pinestreetfoundation.org)
Cancer1
- Cancer Risk Estimation Combining Lung Screening CT with Clinical Data Elements. (cdc.gov)
Standard treatment1
- Nowadays, according to the criteria of Barcelona (BCLC), which is accepted as a worldwide reference, chemoembolization is one of the two standard treatment modalities for intermediate stage HCC. (interventionaloncology.center)
Addition1
- In addition, rare complications such as bile duct damage, abscess and liver failure may occur after chemoembolization. (interventionaloncology.center)
Procedures1
- It includes procedures such as transarterial infusion, hepatic arterial infusion, and intravenous chemotherapy. (pinestreetfoundation.org)
Predict1
- Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis. (institutoomnes.es)
Results1
- Our results suggest that the Child-Pugh classification should not be a limitation to this combined treatment. (unesp.br)
Study1
- Gemcitabine combined with oxaliplatin (GEMOX) in advanced biliary tract adenocarcinoma: a GERCOR study. (cancercentrum.se)