Combination of chemotherapy. Medical search. Frequent questions

As expected, treatment toxicity was greater in the PCV chemotherapy arm and consistent with patients receiving multiagent chemotherapy regimens. (mayoclinic.org)
I. To describe renal toxicity of ifosfamide/carboplatin/etoposide in HRrFHWT and VHRrFHWT patients using conventional and novel biomarkers of renal toxicity (urine NGAL, cystatin C and Kim1) in the context of the chemotherapy regimens used on this study. (clinicaltrials.gov)
In the study conducted by independent investigators, four high-risk acute myeloid leukemia (AML) patients (age range 15 to 20 years) received a significantly higher dose of QUADRAMET than the standard palliative dose in combination with chemotherapy conditioning regimens with melphalan (n = 3) or busulfan/cyclophosphamide (n = 1) as preparatory conditioning regimens prior to hematopoietic stem cell transplantation. (salesandmarketingnetwork.com)
Several platinum-based and non-platinum-based chemotherapy regimens have been used in the treatment of small cell lung cancer (SCLC) with varying results. (medscape.com)
In a systematic review that compared the effectiveness of these regimens, Amarasena et al concluded that platinum-based chemotherapy regimens did not provide a statistically significant benefit over non-platinum-based agents in survival or overall tumor response. (medscape.com)
The investigators suggested that non-platinum-based chemotherapy regimens may have a better risk-benefit profile. (medscape.com)
The PE combination has also been compared with other platinum-based regimens (eg, IP) and has been found to be effective for metastatic SCLC. (medscape.com)
Venetoclax combination with standard regimens in follicular lymphoma, multiple myeloma and aggressive B cell neoplasms has shown some promise, but further studies are required to optimize dose and scheduling to mitigate increased myelosuppression and infection risk, and to find validated biomarkers of venetoclax sensitivity. (biomedcentral.com)
Recent phase 1-2 trials reported manageable safety profiles and promising antitumor activities of anti-PD-1 drugs (pembrolizumab, nivolumab, camrelizumab and JS001) with/without chemotherapy in recurrent/metastatic nasopharyngeal carcinoma (RM-NPC), however head-to-head comparison among these regimens is lacking. (bmj.com)
Toxicity, although greater with the RT-plus-PCV combination, was acceptable, and similar to that seen with many combination chemotherapy regimens commonly in use. (cancertherapyadvisor.com)
Part 1 of this multipart study was designed to evaluate different nivolumab-based regimens versus chemotherapy in two different PD-L1 subgroups. (esmo.org)
The FLT3 inhibitors sorafenib, midostaurin, quizartinib and gilteritinib have been tested in monotherapy in several settings including refractory or relapsed AML (R/R AML), post-transplant maintenance as well as in combination with intensive chemotherapy (ICT) or non-intensity regimens. (dovepress.com)
as monotherapy for the treatment of those patients who have received at least two chemotherapy regimens for their metastatic disease. (who.int)

This is known as adjuvant chemotherapy. (drugs.com)
Your doctor may recommend adjuvant chemotherapy if you have a high risk of the cancer recurring or spreading to other parts of your body (metastasizing), even if there is no evidence of cancer after surgery. (drugs.com)
42 Adjuvant chemotherapy is given after a local treatment (radiotherapy or surgery). (wikipedia.org)
These micrometastases can be treated with adjuvant chemotherapy and can reduce relapse rates caused by these disseminated cells. (wikipedia.org)
The discussant for this presentation, Martin J. van den Bent, MD, of Erasmus University Medical Center, Rotterdam, The Netherlands, said that as of 2014, the role of adjuvant chemotherapy after or with RT has been established in all diffuse glioma types and that understanding of the molecular subtypes that benefit from adjuvant chemotherapy has increased. (cancertherapyadvisor.com)
following surgery, chemotherapy (neoadjuvant or adjuvant) and radiotherapy (if applicable) (see section 5.1) - following adjuvant chemotherapy with doxorubicin and cyclophosphamide, in combination with paclitaxel or docetaxel - in combination with adjuvant chemotherapy consisting of docetaxel and carboplatin. (who.int)

Despite substantial advancements in these basic medicines, which include surgery, radiotherapy, and chemotherapy, their devastating side effect profiles have kept the search for novel cancer treatments alive. (persistencemarketresearch.com)
Cochrane Abstracts , Evidence Central , evidence.unboundmedicine.com/evidence/view/Cochrane/431430/all/Chemotherapy_and_or_radiotherapy_in_combination_with_surgery_for_ovarian_carcinosarcoma. (unboundmedicine.com)
Treatment includes hormone therapy, chemotherapy and radiotherapy. (cancerresearchuk.org)
RAPOSO, Bárbara e ALENCAR, Maria José dos S. . Clinical and therapeutic approach of radiotherapy and chemotherapy induced oral mucositis in cancer patients . (bvsalud.org)
Cancer is a severe pathology and its treatment generally includes radiotherapy, chemotherapy, surgery or a combination of them. (bvsalud.org)
Concurrent use of chemotherapy and radiotherapy results in more severe and prolonged mucositis. (bvsalud.org)

Combination chemotherapy with cyclophosphamide and doxorubicin produced a complete remission of the metastatic thymoma which has continued for 13 months. (duke.edu)
The combination of cyclophosphamide, doxorubicin (Adriamycin), and vincristine (CAV) has been compared with PE in at least 2 randomized trials of previously untreated extensive-stage SCLC and showed similar survival outcomes. (medscape.com)
All patients received rituximab in combination with cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) for varying durations. (elsevierpure.com)

New strategies to discover drugs or drug combinations with higher barriers to resistance are needed. (nih.gov)
Chemotherapy for breast cancer uses drugs to target and destroy breast cancer cells. (drugs.com)
In the process of targeting fast-growing cancer cells, chemotherapy drugs can also damage other fast-growing healthy cells, such as those in the hair follicles, bone marrow and digestive tract. (drugs.com)
Worldwide revenue from the chemotherapy drugs market is estimated to reach US$ 157.7 Bn in 2022, with the global market forecasted to surge ahead at a CAGR of 7.7% to reach a valuation of US$ 331.3 Bn by the end of 2032. (persistencemarketresearch.com)
The global market for chemotherapy drugs recorded a historic CAGR of 6.4% in the last 9 years from 2012 to 2021. (persistencemarketresearch.com)
Overall, chemotherapy drug sales accounted for 87.6% of the global oncology cancer drugs market in 2021. (persistencemarketresearch.com)
As a result, the global number of patients treated is expanding at an exponential rate, creating opportunities for the chemotherapy drugs industry. (persistencemarketresearch.com)
Why is the Global Chemotherapy Drugs Market Growing? (persistencemarketresearch.com)
There have been multiple launches, and the FDA has approved many drugs with novel characteristics and combinations. (persistencemarketresearch.com)
Can Demand for Chemotherapy Drugs Be Affected in Any Way? (persistencemarketresearch.com)
Chemotherapy drugs target cells that replicate quickly, such as cancer cells. (healthline.com)
A combination of chemotherapy drugs is often administered together with radiation therapy in people with limited stage SCLC to try to cure the cancer. (healthline.com)
Half of people treated with platinum chemotherapy drugs and etoposide live at least 25 to 30 months , and 30% to 35% of people live at least 5 years. (healthline.com)
Doctors usually treat SCLC with a combination of chemotherapy drugs. (healthline.com)
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. (wikipedia.org)
Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs) or it may aim to prolong life or to reduce symptoms (palliative chemotherapy). (wikipedia.org)
Importantly, the use of drugs (whether chemotherapy, hormonal therapy or targeted therapy) constitutes systemic therapy for cancer in that they are introduced into the blood stream and are therefore in principle able to address cancer at any anatomic location in the body. (wikipedia.org)
Many of the side effects of chemotherapy can be traced to damage to normal cells that divide rapidly and are thus sensitive to anti-mitotic drugs: cells in the bone marrow, digestive tract and hair follicles. (wikipedia.org)
Because of the effect on immune cells (especially lymphocytes), chemotherapy drugs often find use in a host of diseases that result from harmful overactivity of the immune system against self (so-called autoimmunity). (wikipedia.org)
55-59 Combined modality chemotherapy is the use of drugs with other cancer treatments, such as surgery, radiation therapy, or hyperthermia therapy. (wikipedia.org)
55-59 Combination chemotherapy involves treating a person with a number of different drugs simultaneously. (wikipedia.org)
A number of randomized trials have tried to answer questions concerning the superiority of combination over single-agent chemotherapy, the number of drugs to be used in combination, and dose intensity. (medscape.com)
Last week, the U.S. Food and Drug Administration (FDA) approved a new combination of drugs, formulated together in a single pill called Lonsurf (previously known as TAS-102), to treat patients with advanced colorectal cancer that is no longer responding to other treatments after the treatment was shown in a double-blind, placebo-controlled, phase III clinical trial to extend overall survival. (aacr.org)
Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. (survivornet.com)
We aimed to comprehensively compare the efficacy and safety of different anti-PD-1 drugs, standard chemotherapy, and their combination therapy in RM-NPC. (bmj.com)
Anthracycline chemotherapy drugs damage the DNA in cancer cells, so they cannot reproduce. (medicalnewstoday.com)
Twenty years ago, these patients would have been treated with intensive chemotherapy, including drugs that lead to heart problems later in life. (themedicaldispatch.com)
An earlier Children's Oncology Group trial showed that children with APL who were treated with arsenic trioxide and all-trans retinoic acid, along with chemotherapy drugs that included anthracyclines, had high rates of two-year event-free survival and low risk of relapse. (themedicaldispatch.com)
Vinorelbine is often used in combination with other chemotherapy drugs to increase its effectiveness, but this can also increase the risk of side effects. (mesotheliomausa.net)
In this answer, we will discuss the side effects of using vinorelbine in combination with other chemotherapy drugs. (mesotheliomausa.net)
When vinorelbine is used in combination with other chemotherapy drugs, the risk of bone marrow suppression increases. (mesotheliomausa.net)
When vinorelbine is used in combination with other chemotherapy drugs, the risk of these side effects increases. (mesotheliomausa.net)
Hair Loss: Chemotherapy drugs can cause hair loss, which can be temporary or permanent. (mesotheliomausa.net)
Mouth Sores: Chemotherapy drugs can cause mouth sores, which can be painful and make it difficult to eat or drink. (mesotheliomausa.net)
Diarrhea: Chemotherapy drugs can cause diarrhea, which can be severe in some cases. (mesotheliomausa.net)
Allergic Reactions: Some people may have an allergic reaction to chemotherapy drugs, including vinorelbine. (mesotheliomausa.net)
When vinorelbine is used in combination with other chemotherapy drugs, the risk of allergic reactions increases. (mesotheliomausa.net)
BARCELONA, Spain - New data have shown that first-line treatment with a combination of two immunotherapy drugs improves overall survival in a subset of patients with advanced non-small cell lung cancer (NSCLC) compared to chemotherapy (1). (esmo.org)
Jan. 26, 2022 Researchers have demonstrated that a novel combination of two drugs that act as targeted inhibitors, delivered in a nanoparticle formulation, extend the survival of mice with medulloblastoma. (sciencedaily.com)
Vincristine can be given in combination with other cancer drugs. (macmillan.org.uk)
Your nurse usually gives you anti-sickness (anti-emetic) drugs before the chemotherapy. (macmillan.org.uk)
Single drug or a combination of different drugs to kill cancer cells. (medicinenet.com)
There are many chemotherapy drugs. (epnet.com)
Most are a combination of drugs. (epnet.com)
Surveys have shown that many patients and their loved ones believe nausea and vomiting occur with all types of chemotherapy (anti-cancer drugs). (cancercare.org)
In reality, half of the chemotherapy drugs now in use became available in the past several years, and their side effects are not necessarily the same as those caused by older drugs. (cancercare.org)
That's especially crucial if you are receiving chemotherapy in pill form, as you will need to take the chemotherapy and the anti-nausea drugs in a certain order and at a certain time of day. (cancercare.org)
Safe handling of hazardous chemotherapy drugs in limited-resource settings. (cdc.gov)
1996). With approximately 100 different antineoplastic drugs now in use (NIOSH 2004, 2012) and many more under development, chemotherapy has opened new avenues, providing remission from the disease and the possibility of a cure in some cases. (cdc.gov)
This monograph describes in detail the rationale for and approaches to implementation of these alternative approaches to safe handling of hazardous chemotherapy drugs in low-resource settings. (cdc.gov)

What are the side effects of chemotherapy for SCLC? (healthline.com)
This results in the most common side-effects of chemotherapy: myelosuppression (decreased production of blood cells, hence also immunosuppression), mucositis (inflammation of the lining of the digestive tract), and alopecia (hair loss). (wikipedia.org)
Bone Marrow Suppression: One of the most common side effects of chemotherapy is bone marrow suppression, which can lead to a decrease in the number of red blood cells, white blood cells, and platelets. (mesotheliomausa.net)
It is important for patients to discuss the potential side effects of chemotherapy with their healthcare provider before starting treatment. (mesotheliomausa.net)

Trying the same chemotherapy regimen again is recommended for relapses that occur more than 6 months after the initial therapy. (healthline.com)
If your relapse occurs within 6 months of your treatment, it's generally recommended to try a different regimen with a single chemotherapy drug. (healthline.com)
Several chemotherapy combinations are active in SCLC, but usually a platinum-containing regimen is chosen. (medscape.com)
The chemotherapy regimen may also be adjusted if there are severe side effects. (epnet.com)

Trilaciclib drug was introduced in 2021 for bone marrow suppression, which is the first of its kind to minimize the incidence of chemotherapy-influenced bone marrow suppression amongst persons receiving specific types of chemotherapy treating advanced-stage small cell lung cancer. (persistencemarketresearch.com)
We have now determined that PID1 increases the killing effect of etoposide and cisplatin, two common types of chemotherapy. (sciencedaily.com)

The FDA has granted priority review to Merck's supplemental Biologics License Application for pembrolizumab (Keytruda) in combination with pemetrexed (Alimta) and platinum chemotherapy as first-line treatment for patients with metastatic nonsquamous non-small cell lung cancer (NSCLC). (ajmc.com)
Ganetespib, a highly potent, small-molecule Heatshock protein 90 inhibitor, has potential efficacy in malignant pleural mesothelioma (MPM) via activity on critical survival pathways and known synergies with antifolates and platinum chemotherapy. (aacrjournals.org)

Keytruda is the first immunotherapy to significantly extend survival of patients with NSCLC in combination with chemotherapy as a first-line treatment, including in patients whose tumors are either PD-L1 negative or are untested," said Roger M. Perlmutter, MD, president, Merck Research Laboratories, in a statement. (ajmc.com)
Earlier this month, pembrolizumab monotherapy as first-line treatment in locally advanced or metastatic NSCLC met its primary endpoint of overall survival in the phase 3 KEYNOTE-042 trial when compared to platinum-based chemotherapy. (ajmc.com)
Our early results, reported at a median patient follow-up of 5.9 years, showed that radiation therapy plus PCV chemotherapy was associated with a statistically significant prolongation of median progression-free survival, but not with overall survival. (mayoclinic.org)
Median progression- free survival time for patients receiving radiation therapy plus PCV chemotherapy versus radiation therapy alone was 10.4 years and 4.0 years, respectively. (mayoclinic.org)
Ten-year, progression-free survival and overall survival rates for patients in the radiation therapy plus PCV chemotherapy arm versus those in the radiation therapy alone arm were 51 percent versus 21 percent and 60 percent versus 40 percent, respectively. (mayoclinic.org)
The favorable prognostic variables researchers identified for progression-free and overall survival included the radiation plus PCV chemotherapy arm and oligodendroglioma histology. (mayoclinic.org)
Consolidation chemotherapy is given after remission in order to prolong the overall disease-free time and improve overall survival. (wikipedia.org)
Nonrandomized trials of combination chemotherapy have shown superior response rates and survival compared with single-agent chemotherapy. (medscape.com)
However, in the phase III clinical trial that led to the FDA approval of TAS-102, results of which were published in The New England Journal of Medicine, the new combination chemotherapeutic pill extended survival even for those patients who had colorectal cancer that was no longer responding to treatment with fluorouracil-containing treatments. (aacr.org)
Patients are in need of new treatments that can improve survival outcomes, and these positive results support the potential of KEYTRUDA in combination with chemotherapy as a first-line treatment for patients with the most common form of malignant mesothelioma. (merck.com)
CheckMate-227 is the first trial showing that the combination of nivolumab and ipilimumab prolongs survival as compared to chemotherapy in treatment-naïve patients with metastatic NSCLC," said study first author Prof. Solange Peters, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. (esmo.org)
The survival rate of acute lymphoblastic leukemia (ALL) depends on the age of the patient and the response to chemotherapy. (medicinenet.com)
If cancer has already spread (metastasized) to other parts of the body at the time a leiomyosarcoma is found, then chemotherapy may lead to slightly longer survival. (msdmanuals.com)

Patients were randomized to 1 of 2 trial arms, radiation therapy plus six cycles of PCV chemotherapy or radiation therapy alone. (mayoclinic.org)
Chemotherapy for breast cancer frequently is used in addition to other treatments, such as surgery, radiation or hormone therapy. (drugs.com)
Your healthcare team may use chemotherapy alone if you cannot undergo radiation therapy. (healthline.com)
Surgery may sometimes be combined with radiation therapy and chemotherapy if the cancer is limited to one lung and nearby lymph nodes. (healthline.com)
For the approximately 30% of patients with SCLC who have limited-stage disease at the time of diagnosis (ie, tumors confined to the hemithorax of origin, the mediastinum, or the supraclavicular lymph nodes), management typically involves combination platinum-based chemotherapy and thoracic radiation therapy given with curative intent. (medscape.com)
Photoimmunotherapy (PIT) is an experimental technique now in clinical trials if your head and neck cancer is not responding to radiation or chemotherapy, or when surgery is not feasible because the tumor is too hard to reach. (rush.edu)

Elderly patients with SCLC who have a good performance status (PS) (ie, Eastern Cooperative Oncology Group [ECOG] PS 0 or 1) and intact organ function should receive standard carboplatin-based chemotherapy. (medscape.com)
Common combinations include cisplatin/etoposide (PE), cisplatin/irinotecan (IP), carboplatin/etoposide, and carboplatin/irinotecan. (medscape.com)

However, even those who have poor prognostic factors (eg, poor PS, medically significant concomitant conditions) may still be considered for chemotherapy if appropriate precautions are taken to avoid excessive toxicity and further decline in PS. (medscape.com)

The trial evaluated KEYTRUDA in combination with chemotherapy for the treatment of patients with unresected advanced malignant pleural mesothelioma. (merck.com)

Herein, we report our institutional experience of using rituximab with multiagent chemotherapy for pediatric FL. (elsevierpure.com)

Extensive stage SCLC is most commonly treated with a combination of chemotherapy and immunotherapy . (healthline.com)
[10] In those with significant symptoms, chemotherapy , immunotherapy , or chemoimmunotherapy may be used. (wikipedia.org)
Considering the limitations of the trial, Peters explained that it started before chemotherapy/immunotherapy or immunotherapy alone was approved for the front-line treatment of NSCLC, so the two-drug immunotherapy combination was not compared with current standards of care. (esmo.org)
We need to understand which treatment is best for each patient: chemotherapy plus immunotherapy, immunotherapy alone or immunotherapy plus immunotherapy. (esmo.org)

Proper management of these side effects can help improve the quality of life of patients undergoing chemotherapy. (mesotheliomausa.net)

Does Small-Cell Lung Cancer (SCLC) Respond to Chemotherapy? (healthline.com)
Up to 80% of limited stage SCLC cases respond to chemotherapy. (healthline.com)
Clearly, PID1 has a role in how cells respond to chemotherapy," said Erdreich-Epstein. (sciencedaily.com)

But because the effects of chemotherapy are dangerous to the fetus, talk with your doctor about appropriate birth control options before treatment begins. (drugs.com)

Limited stage SCLC is highly sensitive to chemotherapy - it responds to chemotherapy treatment 60% to 80% of the time. (healthline.com)
Research done in the last decade has shown that certain tumors of the brain and spinal cord, are sensitive to chemotherapy. (sciencedaily.com)

Scholars@Duke publication: Metastatic thymoma with myasthenia gravis: complete remission with combination chemotherapy. (duke.edu)
Maintenance chemotherapy is a repeated low-dose treatment to prolong remission. (wikipedia.org)
Combination chemotherapy was used in induction of complete remission in patients with advanced Hodgkin's disease. (jamanetwork.com)

At the final analysis of the study, KEYTRUDA plus chemotherapy showed a statistically significant and clinically meaningful improvement in OS compared to chemotherapy alone in these patients. (merck.com)

55-59 Intensification chemotherapy is identical to consolidation chemotherapy but a different drug than the induction chemotherapy is used. (wikipedia.org)

If marrow involvement is still present at harvest, then 2 additional courses of induction chemotherapy are given. (knowcancer.com)
Induction chemotherapy is the first line treatment of cancer with a chemotherapeutic drug. (wikipedia.org)

The trial is the confirmatory trial for KEYNOTE-021, a phase 2 study that led to pembrolizumab being the first FDA-approved anti-PD-1 therapy in combination with chemotherapy for the first-line treatment of patients with metastatic nonsquamous NSCLC, regardless of PD-L1 expression. (ajmc.com)
Chemotherapy plays a critical role in treating SCLC and NSCLC. (healthline.com)
This is critical because SCLC, which responds well to chemotherapy and is generally not treated surgically, can be confused on microscopic examination with NSCLC. (cancer.gov)
The data from the CheckMate-227 trial, reported at the ESMO Congress 2019 , suggest that the combination of nivolumab plus low-dose ipilimumab could offer a chemotherapy-free option for first-line treatment of patients with advanced NSCLC. (esmo.org)
The comparison was chemotherapy alone, but this is no longer the standard for patients with metastatic NSCLC," she said. (esmo.org)

Among patients with colorectal cancer (CRC) treated with oxaliplatin (L-OHP)-based chemotherapy, delayed chemotherapy-induced nausea and vomiting (CINV) have not been well controlled. (biomedcentral.com)
Oxaliplatin and oral capecitabine combination chemotherapy showed significant activity and favorable toxicity in patients with metastatic colorectal cancer. (e-crt.org)

Pembrolizumab plus chemotherapy in metastatic non-small-cell lung cancer. (ajmc.com)

Precision medicine has increased the demand for stage-specific cancer chemotherapy. (thno.org)
Liu, W. A stage-specific cancer chemotherapy strategy through flexible combination of reduction-activated charge-conversional core-shell nanoparticles. (thno.org)
Other DNA building block analogues, such as fluorouracil, have been a mainstay of cancer chemotherapy for decades. (aacr.org)

Systemic Chemotherapy for Metastatic Colorectal Cancer. (epnet.com)
Neoadjuvant bidirectional intraperitoneal/systemic chemotherapy (NIPS) is performed for 3 cycles, and then laparotomy is performed. (lu.se)

Limitation of Use: Patients should have disease progression on trastuzumab prior to initiation of treatment with Tykerb in combination with capecitabine. (hdkino.org)
This research study is studying the combination of venetoclax and chemotherapy as a possible treatment for acute myelogenous leukemia (AML). (dana-farber.org)
If breast cancer has spread to other parts of your body and surgery isn't an option, chemotherapy can be used as the primary treatment. (drugs.com)
These side effects often go away after treatment is finished or within a year after completing chemotherapy. (drugs.com)
How is chemotherapy used in the treatment of SCLC? (healthline.com)
Chemotherapy is used to treat all stages of SCLC, but the goal of treatment changes depending on how advanced your cancer is. (healthline.com)
55-59 : 17-18 Neoadjuvant chemotherapy is given prior to a local treatment such as surgery, and is designed to shrink the primary tumor. (wikipedia.org)
Many cancer patients experience diarrhea while they're undergoing chemotherapy treatment. (dana-farber.org)
We pooled data from two prospective observational studies in Japan and one phase III clinical trial to assess whether delayed CINV could be controlled with a combination of three antiemetics adding a neurokinin-1 receptor antagonist and identified individual risk factors, using an inverse probability treatment-weighted analysis. (biomedcentral.com)
Chemotherapy is a common treatment for metastatic prostate cancer. (cancerresearchuk.org)
The as-synthesized MoS2-PEG- Biotin -Cur/Er, featuring high targeting ability , NIR light -responsive drug release , and the integration of synergistic chemotherapy and PTT, may provide a promising strategy for the treatment of lung cancer in clinical practice. (bvsalud.org)
The combination of all-trans retinoic acid and arsenic trioxide is currently the preferred initial treatment for adults with standard-risk APL. (themedicaldispatch.com)
Adult patients with high-risk APL also receive some chemotherapy, as well as maintenance therapy (further treatment to prevent the leukemia from coming back). (themedicaldispatch.com)
Vinorelbine is a chemotherapy drug used in the treatment of various types of cancer, including non-small cell lung cancer, breast cancer, and ovarian cancer. (mesotheliomausa.net)
We already have several front-line treatment options for these patients, including chemotherapy combined with an anti-PD1 agent or an anti-PDL1 agent alone. (esmo.org)
Unfortunately, we did not include a treatment arm with the combination of chemotherapy plus nivolumab in the PD-L1 positive cohort, but only in the negative one," she said. (esmo.org)
Historically, chemotherapy played a small role in the treatment of brain tumors. (sciencedaily.com)
During treatment you usually see a cancer doctor, a chemotherapy nurse or a specialist nurse, and a specialist pharmacist. (macmillan.org.uk)
The high level of treatment failure as well as gametocy- taemia necessitates the introduction of artesunate in this area in combination therapy. (who.int)
Biocon Biologics Ltd), BT-ON014 - in combination with docetaxel for the treatment of those patients who have not received chemotherapy for their metastatic disease - in combination with an aromatase inhibitor for the treatment of postmenopausal patients with hormone-receptor positive MBC, not previously treated with trastuzumab. (who.int)
BT-ON014 trade name] treatment should only be initiated by a health care provider experienced in the administration of cytotoxic chemotherapy (see section 4.4), and should be administered by a health care provider only. (who.int)
Treatment for many of these cases relies principally upon antineoplastic chemotherapy (Chabner et al. (cdc.gov)
Recently, Peritoneal Surface Oncology Group International (PSOGI) developed a novel comprehensive treatment consisting of cytoreductive surgery (CRS) and perioperative chemotherapy (POC) for the treatment of peritoneal metastases (PM) from gastric cancer with curative intent. (lu.se)

Chemotherapy can be used to increase the chance of a cure, decrease the risk of the cancer returning, alleviate symptoms from the cancer or help people with cancer live longer with a better quality of life. (drugs.com)
Late stage SCLC isn't usually considered curable, but chemotherapy can help prolong your life and reduce your symptoms. (healthline.com)
Chemotherapy may be given with a curative intent or it may aim to prolong life or to palliate symptoms. (wikipedia.org)
Though many people receiving chemotherapy may still experience nausea and vomiting, your health care team has many ways to both prevent and ease these symptoms. (cancercare.org)
Others don't feel symptoms the day of chemotherapy but develop nausea and vomiting during the following few days (a delayed reaction). (cancercare.org)

Vincristine is a chemotherapy drug used to treat many types of cancer. (macmillan.org.uk)
You will be given vincristine in the chemotherapy day unit or during a stay in hospital. (macmillan.org.uk)
If you are having vincristine in combination with another chemotherapy drug called doxorubicin , the infusion may be given over a few days using a pump that you take home. (macmillan.org.uk)

Chemotherapy for colorectal cancer is usually given through an IV. (epnet.com)

After you have surgery to remove the breast cancer, your doctor may recommend chemotherapy to destroy any undetected cancer cells and reduce your risk of the cancer recurring. (drugs.com)
Chemotherapy is sometimes given before surgery (known as neoadjuvant therapy or preoperative chemotherapy) to shrink larger cancers. (drugs.com)
You may have surgery to remove the tumor or lymph nodes before receiving chemotherapy. (healthline.com)
2 cm in diameter, as adjuvant therapy following neoadjuvant chemotherapy and surgery (see sections 4.4 and 5.1). (who.int)
Surgery and chemotherapy are used less often. (msdmanuals.com)
The chemotherapy drug imatinib has been found to be effective in treating leiomyosarcoma that cannot be treated with surgery. (msdmanuals.com)

55-59 Salvage chemotherapy or palliative chemotherapy is given without curative intent, but simply to decrease tumor load and increase life expectancy. (wikipedia.org)
Remarkably, MoS2-PEG- Biotin -Cur/Er achieved the combination of synergistic chemotherapy and photothermal therapy (PTT) upon NIR irradiation, effectively suppressing lung cancer cell proliferation and inhabiting tumor growth in vivo. (bvsalud.org)
To determine how PID1 interacts with chemotherapy, the researchers engineered tumor cells to overexpress, or increase production, of PID1. (sciencedaily.com)

The aim of this study (JGOG1063) was to determine the recommended dose (RD) for combination chemotherapy with irinotecan hydrochloride (CPT-11) and nedaplatin (NDP) for advanced cervical squamous cell carcinoma. (nih.gov)

Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called medical oncology. (wikipedia.org)
Your oncology care providers now have many ways to prevent and ease nausea and vomiting from chemotherapy. (cancercare.org)

Chemotherapy is one of six standard treatments used for SCLC. (healthline.com)
Common treatments include chemotherapy and hormone therapy. (cancerresearchuk.org)
Prior chemotherapy must have included at least an anthracycline and a taxane unless patients are unsuitable for these treatments. (who.int)

Whereas chemotherapy-induced nausea and vomiting (CINV) were less prevalent for CRC patients on fluorouracil-based chemotherapy, they are a common adverse event for patients treated with L-OHP. (biomedcentral.com)
Taking a combination of two antiemetics (2antiemetics)-5HT3RAs and steroids-before receiving L-OHP resulted in a 90% complete response (CR) for control of nausea and vomiting during the 24 h after chemotherapy. (biomedcentral.com)
Nausea and Vomiting: Another common side effect of chemotherapy is nausea and vomiting. (mesotheliomausa.net)
Some people experience nausea and vomiting within the first few hours of receiving chemotherapy (known as an acute reaction). (cancercare.org)

It has also been hypothesized that other genetic alterations may be responsible for a small subset of patients whose glial brain tumors are chemotherapy-resistant. (mayoclinic.org)

What is the procedure for anthracycline chemotherapy? (medicalnewstoday.com)
Side effects of anthracycline chemotherapy can range from mild to severe. (medicalnewstoday.com)

It may be used in combination with targeted therapy. (drugs.com)
You usually have it in combination with hormone therapy. (cancerresearchuk.org)
nanosheets for the combination of synergetic chemotherapy and photothermal therapy of lung cancer. (bvsalud.org)
Targeted co-delivery of curcumin and erlotinib by MoS 2 nanosheets for the combination of synergetic chemotherapy and photothermal therapy of lung cancer. (bvsalud.org)

High-risk features included secondary AML and a chromosomal defect known as monosomy 7 (n = 1), chemotherapy induction failure (n = 1), and AML in relapse (n = 2). (salesandmarketingnetwork.com)

AML is usually treated by a combination of cytotoxic drug therapies and in some cases, bone marrow transplantation. (salesandmarketingnetwork.com)

Here, we represent preliminary evidence for the comparative safety and efficacy of existing anti-PD-1 agents with/without chemotherapy in RM-NPC, which indicated that camrelizumab has the least toxicity profile and merits future investigation. (bmj.com)
She noted that CheckMate-227 showed that safety profiles of both strategies are different, in terms of specific toxicity events encountered, their timing, grade and prevalence, with diarrhoea, rash and fatigue being the most common adverse events with nivolumab/ipilimumab and fatigue, gastrointestinal and haematological toxicities with chemotherapy. (esmo.org)

None of the children with standard-risk APL required conventional chemotherapy, and those with high-risk APL received just four doses of the chemotherapy drug idarubicin (Idamycin PFS). (themedicaldispatch.com)
If we can figure out how to block breakdown of PID1, we may be able to prevent drug resistance and make chemotherapy more effective. (sciencedaily.com)
Identifying dedicated areas for hazardous chemotherapy drug storage and compounding, restriction of personnel access to these areas, meticulous adherence to work practices that minimize drug aerosol production and work environment contamination, together with painstaking attention to worker training and skills assessment are the most reasonable set of alternatives to the internationally recognized best-practices approach described above. (cdc.gov)

Future research will focus on overcoming venetoclax resistance, targeting other BCL2 family members and the rational design of synergistic combinations. (biomedcentral.com)

The publication, "Marrow irradiation with high-dose 153 Samarium-EDTMP followed by chemotherapy and hematopoietic stem cell infusion for acute myelogenous leukemia" by Vilmarie Rodriguez, M.D., a Pediatric Oncologist at The Mayo Clinic in Rochester, Minnesota, appears in a recent issue of the peer-reviewed journal Leukemia & Lymphoma (Leuk Lymphoma. (salesandmarketingnetwork.com)
A clinical trial has found that the combination of all-trans retinoic acid, which is a metabolite of vitamin A, and arsenic trioxide is highly effective in children with standard- and high-risk acute promyelocytic leukemia, or APL. (themedicaldispatch.com)

This type of chemotherapy is used for curative intent. (wikipedia.org)

We conducted a dose-escalation study to identify the maximum tolerated dose (MTD) of ganetespib in patients with chemotherapy-naïve MPM. (aacrjournals.org)

Merck has an extensive clinical development program in lung cancer and is advancing multiple registration-enabling studies, with research directed at earlier stages of disease and novel combinations. (merck.com)

Meanwhile, the uptake of recommended preventive chemotherapies for infants, children and pregnant women also remains low. (who.int)
Children born during the campaign and who reached 3 months were eligible to receive preventive chemotherapy. (who.int)

The PE combination is associated with less myelosuppression, whereas CAV has the convenience of administration in a single day (PE requires a 3-day program). (medscape.com)

The only currently approved BH3-mimetic, the selective BCL2 inhibitor venetoclax, is highly efficacious in chronic lymphocytic leukemia and has rapidly advanced to an approved standard of care in frontline and relapsed disease in combination with anti-CD20 monoclonal antibodies. (biomedcentral.com)

Anatomy4

Organisms1

Diseases87

Chemicals and Drugs72

Analytical, Diagnostic and Therapeutic Techniques and Equipment75

Phenomena and Processes10

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena2

Humanities1

Information Science2

Health Care30

Regimens13

Adjuvant chemotherapy6

Radiotherapy6

Cyclophosphamide3

Drugs50

Side effects of c4

Regimen4

Types of chemotherapy2

Platinum chemotherapy2

Survival13

Radiation6

Carboplatin2

Medically1

Pleural Mesothelioma1

Multiagent chemotherapy1

Immunotherapy4

Patients undergoing c1

Respond to chemotherapy3

Effects of chemotherapy1

Sensitive to chemotherapy2

Remission3

Statistically significant1

Consolidation Chemotherapy1

Induction chemotherapy2

NSCLC5

Oxaliplatin2

Plus chemotherapy1

Cancer chemotherapy3

Systemic Chemotherapy2

Treatment23

Symptoms5

Vincristine3

Colorectal1

Surgery6

Tumor3

Irinotecan1

Oncology2

Treatments3

Nausea4

Brain tumors1

Anthracycline2

Therapy4

Relapse1

Cytotoxic1

Toxicity2

Drug3

Synergistic1

Acute2

Curative intent1

Dose1

Lung cancer1

Preventive2

Myelosuppression1

Venetoclax1