In normal patients' colonic mucosa, phagocytic cells do not respond to the resident bacteria. (medscape.com)
UC is characterized by inflammation and ulceration confined to colonic mucosa, whereas CD is manifested by transmural inflammation and granulomas that may affect any segment of the GI tract, including the colon. (medscape.com)
Colonic mucosa with gastrointestinal stromal tumor (GIST) involving adjacent submucosa (hematoxylin and eosin [H&E] stain, medium power). (medscape.com)
Colorectal2
Synchronous occurrence of colorectal adenocarcinoma and colonic gastrointestinal stromal tumor (GIST). (annalsgastro.gr)
Colorectal cancer is a complication of ulcerative colitis and colonic Crohn's disease, the two main forms of idiopathic inflammatory bowel disease (IIBD). (biomedcentral.com)
Human colonic1
Synthesis of type 1 and 2 lacto series glycolipid antigens in human colonic adenocarcinoma and derived cell lines is due to activation of a normally unexpressed beta 1----3N-acetylglucosaminyltransferase. (kegg.jp)
Gastric3
This study compared the long-term consequences of two common forms of bariatric surgery: one-anastomosis gastric bypass (OAGB) and Roux-en-Y Gastric Bypass (RYGB) in a preclinical rat model. (nature.com)
Therefore, the aim of this study was to evaluate the capacity of a concise panel of known BC markers together with GCDFP-15 and HNF4A to accurately distinguish primary gastric adenocarcinoma from metastases to stomach in the Brazilian population. (biomedcentral.com)
Preoperative endoscopic diagnosis and timely treatment are important for the clinical management of sporadically superficial nonampullary duodenal epithelial tumours (SNADETs), including adenoma and adenocarcinoma limited to the submucosal layer. (biomedcentral.com)
Benign or low-grade adenoma can be followed up without biopsy, and high-grade adenoma and adenocarcinoma should be resected by endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), or surgery. (biomedcentral.com)
Superficial nonampullary duodenal epithelial tumours (SNADETs), including adenoma and adenocarcinoma limited to the submucosal layer, are rare, but the treatment outcomes for advanced cases are not satisfactory [ 1 ]. (biomedcentral.com)
Pancreatic ductal adenocarcinoma2
PANCREATIC DUCTAL ADENOCARCINOMA CLINICAL FEATURES Ductal adenocarcinoma of the pancreas is the most common malignant neoplasm of the pancreas. (coek.info)
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related death and is one of the most difficult-to-treat cancers. (biomedcentral.com)
Ductal3
PATHOLOGY Ductal adenocarcinomas are firm to hard mass lesions that are often poorly defined grossly. (coek.info)
Histologically, most ductal adenocarcinomas are composed of glandlike structures embedded in an abundant desmoplastic stroma. (coek.info)
In spite of their aggressive biologic behavior, some ductal adenocarcinomas show bland nuclear features, making the distinction of benign lesion from an invasive carcinoma difficult, particularly on small biopsy specimens (Fig. 1). (coek.info)
Crohn's1
PCDH20 mRNA and protein expression is significantly downregulated in the colonic epithelium of Crohn's disease patients and mice with induced colitis compared with controls. (biomedcentral.com)
Epithelial3
MUC4 is expressed in the cytoplasm of certain epithelial surfaces, such as colonic, breast, and lung epithelia. (chemdict.com)
The intestinal epithelial cell layer mediates selective protection against luminal contents by forming junctional complexes and releasing protective components like phospholipids, mucins, trefoil factor proteins, defensins, and secretory dimeric immunglobulins. (uni-regensburg.de)
According to the morphological growth pattern, lack of proliferative abnormalities and the mucin content of the epithelial cells, 3 subtypes of HP are described 4 , 5 , 6 . (openaccesspub.org)
Metastasis3
Renal metastasis from primary colon cancer is so rare that, from USA, Nelson's associates reported "a unique case of a 51-year-old female with extra luminal colonic adenocarcinoma which directly invaded into the kidney. (symbiosisonlinepublishing.com)
Colonic metastasis of such a tumor is rare, with few case reports available. (hindawi.com)
Adenomas1
Clear cell change is seen in textless1% of colonic tubular adenomas (TAs) and remains incompletely characterized. (tobycornish.com)
Metastatic1
By 2011, 11 cases were reported in the medical literature of colonic adenocacinoma metastatic to the kidney. (symbiosisonlinepublishing.com)
Trefoil1
INTRODUCTION: The colonic mucus layer plays an important role in the protection of the intestinal epithelium and mainly consists of mucin glycoproteins (primarily MUC2 in the colon) trefoil factor 3 (TFF3) and secretory IgA. (tno.nl)
Neoplasms2
Appendiceal goblet cell carcinoid (GCC) and adenocarcinoma ex-goblet cell carcinoid (AdexGCC) have previously been described as two entities in a spectrum of neoplasms showing both glandular/mucinous and neuroendocrine differentiation [ 1 ]. (gastrores.org)
Neoplasms containing cyst-like formations or producing mucin or serum. (lookformedical.com)
Cytoplasm1
The most frequent subtype of HP is the one with microvesicular mucinous cells named mivrovesicular hyperplastic polyp (MVHP) this type is characterized with the presence of small droplet mucin in cytoplasm of the most cells. (openaccesspub.org)
Neuroendocrine1
Adenocarcinoma ex-goblet cell carcinoid (AdexGCC) was considered a neuroendocrine adenocarcinoma, despite majority of tumor cells being negative for conventional neuroendocrine markers such as chromogranin and synaptophysin. (gastrores.org)
Malignancies2
Small-intestinal adenocarcinomas were the first clinical manifestation in 37% (3/8) of Lynch syndrome patients, and second malignancies developed within 5 years in 63% (5/8). (oncotarget.com)
When considering all primary malignancies of the small bowel, adenocarcinomas tend to occur more proximally, whereas carcinoids , lymphomas, and leiomyosarcomas occur more distally. (medscape.com)
Neoplastic1
A small proportion of these tumors show large ducts lined by neoplastic cells, the so-called large-duct variant of adenocarcinoma. (coek.info)
Primary1
The patient developed a new left lung mass 5 years ago, which was diagnosed as a primary lung adenocarcinoma. (hindawi.com)
Immunohistochemistry1
To define the incidence and characteristics of Lynch syndrome-related small-intestinal adenocarcinomas, meticulous familial and clinical histories were obtained from 195 patients with small-intestinal adenocarcinoma, and MMR protein immunohistochemistry, microsatellite instability, MLH1 methylation, and germline mutational analyses were performed. (oncotarget.com)
Expression1
Im intestinalen LS174T Zellkulturmodell führten Stimulationen mit den Zytokinen Tumor Nekrose Faktor alpha (TNFa) und Transformierender Wachstumsfaktor beta (TGFb) zu einer Induktion der Mucin Expression, die durch die beiden NFkB Hemmer Caffeic Acid Phenethyl Ester (CAPE) und Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal (MG132) verhindert werden konnte. (uni-regensburg.de)
A meticulous patient history taking, MMR protein immunolabeling, and germline MMR gene mutational analysis are important for the diagnosis of Lynch syndrome-related small-intestinal adenocarcinomas. (oncotarget.com)
Cell lines1
By administering a selective ATF6 activator, the impairment of intestinal barrier integrity and dysregulation of CHOP/β-catenin/p-p120-catenin pathway was reversed in Pcdh20 -ablated mice with colitis and PCDH20 -deficient colonic cell lines. (biomedcentral.com)
Small1
Small-intestinal adenocarcinomas are common initial manifestations of Lynch syndrome. (oncotarget.com)
Effects2
Ethanol effects on mucin glycosylation: Another kick in the gut? (annalsgastro.gr)
Butyrate is a major end product of fermentation of dietary fibres and is associated with beneficial effects on colonic. (tno.nl)
Risk2
EMR frequently leads to a piecemeal resection, while ESD ensures a high en bloc resection rate with a high risk of complications. (biomedcentral.com)
Laparoscopic endoscopic cooperative surgery is a promising treatment for SNADETs with excellent rates of en bloc resection and a low risk of complications, although it is expensive and requires many specialists. (biomedcentral.com)
Pseudomembranous colitis is a form of inflammatory colitis characterized by the pathologic presence of pseudomembranes consisting of mucin, fibrin, necrotic cells, and polymorphonuclear leukocytes (PMNs). (medscape.com)
Cases2
Hence, the 2 cases, which were found to exhibit both colonic and renal growths, are deemed to be worthy of documentation. (symbiosisonlinepublishing.com)
P =0.04) and more likely to have mucinous adenocarcinomas ( P= 0.003), and tended to survive longer ( P =0.11) than those with sporadic cases. (oncotarget.com)