Collagen and structural proteins collagen and laminin. Medical search. Frequent questions

They are noted for having the ability to degrade extracellular matrix proteins, such as collagens, laminin, and proteoglycans. (wikipedia.org)
All connective tissue is composed of three major classes of biomolecules: structural proteins (collagen and elastin), specialised proteins (fibrillin, fibronectin and laminin), and proteoglycans. (natmedworld.com)
The extracellular matrix (ECM) is a three-dimensional macromolecular network composed of structural proteins (collagens, elastin), adhesion/signalling proteins (fibronectin, laminins), different proteoglycans, glycoproteins and glycosaminoglycans (GAGs). (hcs-pharma.com)
The diversity of proteoglycans and their high interaction with growth factors and their receptors provides structural basis for a multitude of biological functions. (premiumbeautynews.com)
Glycoconjugates (glycoproteins, glycolipids, proteoglycans) are sugar-containing molecules that have many important structural and modulatory functions in biological systems (13). (9lib.net)
The extracellular matrix (ECM), the product of connective tissue, is mainly composed of proteins and proteoglycans. (9lib.net)
This fibrillar network is composed of many structural proteins, such as collagens, and adhesion proteins, including fibronectin and proteoglycans (perlecan, decorin) [ 13 , 14 ]. (springer.com)
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. (cusabio.com)
Other than water, the mesoglea is composed of several substances including fibrous proteins like collagen and heparan sulphate proteoglycans. (pearltrees.com)
2008), such as cell receptors this kind of as integrins, DDR and GPVI, (Leitinger and Hohenester, 2007) as well as other critical ECM molecules, this kind of as fibronectin, laminin and proteoglycans. (dot1linhibitor.com)

We are interested how extracellular matrix proteins instruct cells to differentiate, migrate, and proliferate, and how cells sense normal and pathologically altered extracellular matrix. (mcgill.ca)
Fibrosis is characterised by an excessive production of extracellular matrix components, and cells in the tissue are constantly interacting with these extracellular matrix proteins. (bmj.com)

The extracellular matrix of the amniotic membrane is composed mainly of collagen, fibronectin and laminin. (revmaterialeplastice.ro)

The aim of the present study was to functionalize Ti scaffolds with genetically modified elastin-like recombinamers (ELRs), synthetic polymeric proteins containing the elastin epitopes responsible for their mechanical properties and for promoting mesenchymal stem cell (MSC) recruitment, proliferation, and differentiation to ultimately increase scaffold osseointegration. (ibecbarcelona.eu)
Matrixyl 3000 - Naturally aids in the production of collagen & elastin, reducing the appearance of wrinkles and giving skin a "lifting" effect. (chicagohealthfoods.com)
Acai Berry - Super antioxidant from Brazil that increases levels of hydroxyproline, a vital amino acid required for the synthesis of collagen and elastin. (chicagohealthfoods.com)
Stimulated enzymes to help build new elastin and collagen. (remi-d.com)
Soy protein that prevents elastin breakdown. (remi-d.com)
Collagen and elastin supporter, this is a natural component of the skin. (remi-d.com)

Laminin is an extracellular matrix multidomain trimeric glycoprotein and is the main non-collagenous component of basal lamina that supports adhesion, proliferation and differentiation. (sigmaaldrich.com)
Laminin has active domains for collagen binding, cell adhesion, heparin binding, and neurite outgrowth fragment. (sigmaaldrich.com)
The ECM composed of hundred proteins is a dynamic network controlling the proliferation, adhesion, migration, polarity, differentiation, and apoptosis of the cells. (premiumbeautynews.com)
Extracellular matrix is a fibrillar network composed of structural (collagens) and adhesion (fibronectin) proteins crucial for tissue architecture and biological pathway Histol Histopathol 27:1515-1528, 2012 . (springer.com)
Functional analyses indicated that some of the genes induced by dragonfly larvae caused an increase in laminins necessary for cell adhesion in the extracellular matrix. (biomedcentral.com)
The laminins are an important and biologically active part of the basal lamina, influencing cell differentiation, migration, and adhesion. (pearltrees.com)
Matrix Metalloproteases (MMPs) are zinc-dependent endopeptidases, which degrade mainly components of the extracellular matrix (ECM) such as collagens, fibronectins and laminins, but also proteins responsible for adhesion such as integrins or even other MMPs and are thus a crucial factor for the capability of primary macrophages to detach and migrate through various tissues. (uni-hamburg.de)

Although the molecular identities of these factors have not been reported, collagen-like peptides have been identified in the material produced by arterial and sheath cells 13 . (nature.com)
Packed to the brim with peptides and actives, our face cream is formulated to kick-start collagen production while Mother Nature's best antioxidants neutralize aging free radicals. (chicagohealthfoods.com)
Previously, skin formulations were based on ascorbic acid, tocopherol, niacinamide, retinyl palmitate, anti-aging peptides, and proteins as topical solutions that reduce Reactive Oxygen Species (ROS) [3]. (heraldopenaccess.us)
Due to their large surface area and ability to interact with proteins and peptides, graphene oxides offer valuable physiochemical and biological features for biomedical applications and have been successfully employed for optimizing scaffold architectures for a wide range of organs, from the skin to cardiac tissue. (mdpi.com)
Application of Algae Peptides makes skin grow its own collagen at a faster rate. (remi-d.com)

No specific or efficient treatment exists for Alport syndrome, an X-linked hereditary disease caused by mutations in collagen type IV, a crucial component of the glomerular basement membrane. (hindawi.com)
Laminin and type IV collagen are the two principal components of the basement membrane. (biogenex.com)
Because type IV collagen and laminin are proteins found exclusively in the basement membrane, the antibodies to these two proteins selectively and specifically recognize basement membrane components. (biogenex.com)
Laminin consists of a 220 kD subunit, which is disulfide-linked into larger complexes or even into the structural scaffolding of the basement membrane itself. (biogenex.com)
In surgical pathology, laminin can be used as a marker to demonstrate morphologic change of basement membrane, which is helpful for interpreting the invasion of malignant tumors. (biogenex.com)
TGF-β2 is capable of inducing the expression of ECM and basement membrane components in cultured ONH astrocytes via CTGF and upregulated TSP-1, a protein naturally involved in the activation of latent TGF-β. (arvojournals.org)
As a basement membrane protein, COL4A1 is commonly expressed in many tissues and cell types. (cusabio.com)
They are a major component of the basal lamina (one of the layers of the basement membrane), a protein network foundation for most cells and organs. (pearltrees.com)
While human fibril forming collagens all have a excellent (Gly-Xaa-Yaa)n amino acid sequence pattern inside their triple-helix region, nonfibrillar collagens (such as basement membrane form IV collagen) incorporate websites in which this repeat is broken. (dot1linhibitor.com)

Inside the sequence of fibril-forming collagens, you'll find regarded binding sites for greater than 50 biologically practical molecules (Sweeney et al. (dot1linhibitor.com)

Other acquired skin diseases of the hemidesmosomes reveal autoantibodies to a plectin-like protein, the β 4 subunit of α 6 β 4 integrin, uncein and a not yet characterized 168 kDa protein. (uni-luebeck.de)
ELAV - like1 , methyltransferase like 7A , dolichyl-phosphate mannosyltransferase , laminin subunit beta-1 , gremlin 1 , BCL6 corepressor-like 1 , and three genes of unknown identity. (biomedcentral.com)
The subunits are held together and connected to the underlying cell surface by non-covalent interactions, and they spontaneously reassemble in vitro by an entropy-driven process, i.e. the subunit proteins are very poorly water-soluble [ 8 ]. (biomedcentral.com)

ECM components (i.e., fibronectin or collagens) directly interact with membrane receptors (i.e., integrins), particularly, by influencing cell behavior. (springer.com)
For instance, in some S. pyogenes strains, the CL domain of Scl1 protein can interact with integrins 21 and 111 as a IL-17 Inhibitor Biological Activity result of the sequence GLPGER (Caswell et al. (dot1linhibitor.com)

Deposition of collagen and proliferation of smooth muscle cells are the response to chronic inflammation and injury of the submucosa leading to fibrosis and thickening of the submucosa and the smooth muscle layers of the bowel wall. (bmj.com)
In addition to providing structural integrity, ECM delivers important spatial and contextual cues to drive varied behaviors such as proliferation, migration, epithelial-to-mesenchymal transition, apoptosis, and production of various secreted mediators (as reviewed in References 1 - 3 , among others). (atsjournals.org)

Currently, numerous surgical societies recommend nutritional supplementation with specific proteins, amino acids, and vitamins both before and immediately after surgery for improved outcomes and faster healing. (zennutrients.com)
In particular, cortisol stimulates the degradation of amino acids from collagen. (natmedworld.com)

Collagen is the main protein of connective tissue. (natmedworld.com)
ALLATONIN Allantoin is a natural soothing, anti-irritant, and skin protectant that increases the water content of the extracellular matrix which provides structural support to cells and is an important part of connective tissue. (remi-d.com)

These zones are mainly composed of collagen IV, plectin, laminin (proteins of BM), and nidogen in the upper regions, collagen IV, VI, anchoring fibrils, and heparan sulfate proteoglycan (proteins of LD) [8]. (heraldopenaccess.us)
The major structural component of anchoring fibrils is type VII collagen, the autoantigen of epidermolysis bullosa acquisita. (uni-luebeck.de)

This mimicry triggers B- and T-cell immune responses directed against the heart, joints, central nervous system (CNS), skin, and subcutaneous tissues where those proteins are found. (medscape.com)
When ARF develops, exudative and proliferative inflammatory lesions can appear in connective tissues of the joints, blood vessels, and subcutaneous tissue, but they are especially detrimental in cardiac tissue, where structural changes can occur, resulting in rheumatic heart disease (RHD). (medscape.com)
The body will divert energy and protein from other tissues to the wound bed causing dysregulation and further slowing the healing process. (zennutrients.com)
Laminin proteins are integral components of structural scaffolding in animal tissues. (sigmaaldrich.com)
Elastic tissues such as the skin require a strong and resilient structural framework. (natmedworld.com)
Collagens are crucial for the ECM architecture and particularly collagen I, III and VI are key components in animal tissues. (springer.com)
Introduction of biological practical sequences Animal collagen may be the big cIAP-1 Antagonist supplier structural protein delivering physical help of tissues, and in addition has a variety of biological functions by interacting with cell surface receptors and also other extracellular matrix molecules. (dot1linhibitor.com)

It is due to different mutations in collagen IV [ 1 ]. (hindawi.com)
Mechano-bullous diseases have been attributed to at least 1,000 different mutations in 20 separate genes that code for various structural proteins near the junction of the epidermis and the dermis (the top layers of skin). (medicinenet.com)
Mutations in GPR56 , an orphan G-protein-coupled receptor (GPCR), cause bilateral frontoparietal polymicrogyria (BFPP), a disorder characterized by mental retardation, seizures, motor developmental delay, and ataxia. (jneurosci.org)

Ghasemi-Mobarakeh L, Prabhakaran MP, Tian L, Shamirzaei-Jeshvaghani E, Dehghani L, Ramakrishna S. Structural properties of scaffolds: Crucial parameters towards stem cells differentiation. (wjgnet.com)
To this end, we entrapped collagen type I, laminin-111, or fibronectin in ECM composites with MSCs and directly compared markers of mesodermal differentiation including cardiomyogenic (ACTC1), osteogenic (SPP1), adipogenic (PPARG), and chondrogenic (SOX9) in 2D versus 3D. (umn.edu)
We found the 3D condition largely mimicked the 2D condition such that the addition of type I collagen was the most potent inducer of differentiation to all lineages tested. (umn.edu)
One notable difference between 2D and 3D was pronounced adipogenic differentiation in 3D especially in the presence of exogenous collagen type I. In particular, PPARG gene expression was significantly increased ∼16-fold relative to chemical induction, in 3D and not in 2D. (umn.edu)
Thus, this novel biomaterial platform allowed us to compare the biochemical impact of whole-molecule ECM proteins in 2D versus 3D indicating enhanced adipogenic differentiation and IL-6 expression of MSC in the 3D context. (umn.edu)
Exploiting the biochemical impact of ECM proteins on MSC differentiation and immunomodulation could augment the therapeutic utility of MSCs. (umn.edu)

This combination increased outgrowth and branching relative to either laminin or hemolymph alone. (nature.com)

During the initial infection, alpha-helical M proteins (M8 and M13) on the surface of the streptococcus bind type IV collagen in the host, and this interaction can trigger auto-antibody formation. (medscape.com)
They associate with type IV collagen via entactin and perlecan and bind to cell membranes through integrin receptors, dystroglycan glycoprotein complexes and Lutheran blood group glycoproteins. (sigmaaldrich.com)
network-forming non fibrillar collagens (type IV), that composed a non-fibril network. (premiumbeautynews.com)
fibril-associated collagens (types IX, XII), and others (type VI). (premiumbeautynews.com)
In fact, levels of IL-6 gene expression in 3D composites containing exogenously supplied collagen type I or fibronectin were statistically similar to levels attained in 2D with tumor necrosis factor-α (TNF-α) stimulation and these levels were sustained over a 2-week period. (umn.edu)
The mesohyl includes a noncellular colloidal mesoglea with embedded collagen fibers, spicules and various cells, being as such a type of mesenchyme. (pearltrees.com)
Nevertheless, it's been identified that several type of bacterial collagens can interact with mammalian proteins and might perform crucial roles in bacterial residing processes. (dot1linhibitor.com)

Plant MMPs show structural similarity to MMPs found in mammals, such as the presence of an auto-regulatory cysteine switch domain and a zinc-binding catalytic domain. (wikipedia.org)
Similar to that of induced fit by enzyme-substrate interactions, MMPs in the first group, called collagenases, have interstitial collagens. (wikipedia.org)
Moreover, collagens interact with matrix metalloproteinases (MMPs), which degrade the matrix and perform a crucial position in physiological and pathological processes, this kind of as wound healing, tissue repair, angiogenesis, arthritis and metastasis (Visse and Nagase, 2003). (dot1linhibitor.com)
Die Abhängigkeit der Protein Expression von „soluble MMPs" von der pro- oder antiinflammatorischen Polarisation ist ein wichtiger Aspekt in Krankheiten, in dem sich diese von MT1-MMP - einem konstitutiv exprimierten MMP in Makrophagen - unterscheiden. (uni-hamburg.de)

The interconnecting complex meshwork of DEJ proteins and the finger-like rete ridges aid in maintaining the skin's structural integrity and mechanical stability. (heraldopenaccess.us)

The second group, called gelatinases, degrade denatured collagens catalytically. (wikipedia.org)
This review summarizes evidence for the role of proteolytic enzymes that degrade and inactivate insulin-like growth factor binding proteins (IGFBP) during follicular development in mammals. (bioone.org)

the tadpoles showed reduced expression of cα(E)-catenin , small muscle protein, dystrophin , and myosin light chain genes. (biomedcentral.com)

The research themes rank around molecular mechanisms matrix proteins and fibers exert in disorders affecting blood vessels, bone, skin and adipose tissue. (mcgill.ca)

Working with recombinant DNA technological innovation, the biologically inert Scl2 collagen-l. (dot1linhibitor.com)

Epidermolysis bullosa is due to one or multiple defective genes that normally synthesize structural proteins that are involved in the adherence of the epidermis (the superficial layer of skin) to the dermis (the deeper layer of the skin). (medicinenet.com)
Another term for this group of conditions is 'mechanobullous disease,' which distinguishes it from conditions that may appear superficially similar but are produced by autoimmune destruction of some of the same proteins that are defective in epidermolysis bullosa. (medicinenet.com)

TissueFab ® - Low endotoxin GelMA-UV Laminin kit enables the precise fabrication of 3D cell models and tissue constructs for research in 3D cell biology, tissue engineering, in vitro tissue models, and regenerative medicine. (sigmaaldrich.com)
This review critically focuses on opportunities to employ protein-graphene oxide structures either as nanocomposites or as biocomplexes and highlights the effects of carbonaceous nanostructures on protein conformation and structural stability for applications in tissue engineering and regenerative medicine. (mdpi.com)

Our results indicate that the active factor is either a high molecular weight protein or protein complex and is not the respiratory protein hemocyanin. (nature.com)
An Illustration of the Laminin-111 complex depicting the domain organization Laminins are high-molecular weight (~400 to ~900 kDa) proteins of the extracellular matrix. (pearltrees.com)

In contrast, in the submucosa, laminin was exclusively found in the basal lamina of blood vessels where many adherent mast cells were seen. (bmj.com)

Protein requirements rise as people age, but their ability to process complex proteins within their GI tract diminishes. (zennutrients.com)
Syn-Tacks - Dual peptide complex that interacts with the most relevant protein structures at the dermal-epidermal juncture to aid in the structural and functional integrity of the skin. (chicagohealthfoods.com)
Hence, the commentary highlights the significance of dermal-epidermal junction proteins, specifically collagen IV, a target of a newly developed complex DL-linefade. (heraldopenaccess.us)

In contrast to expectations, none of the major S-layer proteins of the IPEC-1 -adhering strains mediated bacterial adherence. (biomedcentral.com)

They are composed of numerous identical (glyco)protein subunits (with a 25-71 kDa size in lactobacilli), which form a regular, symmetric and porous array, completely covering the bacterial cell surface. (biomedcentral.com)
It was observed that the variety IV collagen interruptions have been efficiently integrated in to the bacterial triple-helix protein with small effect on total construction or stability. (dot1linhibitor.com)
Considering the fact that bacteria are single-cell organisms without an extracellular matrix, bacterial collagens don't have similar functions as animal collagens. (dot1linhibitor.com)

This "renowned" matrix plays one of the essential roles of the physical and biomechanical properties of the dermis with this intricate network of extracellular macromolecules providing cells structural, bioactive molecules and biochemical support. (premiumbeautynews.com)
Extracellular matrix (ECM) proteins are structural elements of tissue and also potent signaling molecules. (umn.edu)

In addition, several proteins that are not previously linked with blood-biomaterial interaction are presented and discussed. (ibecbarcelona.eu)
The purpose of our study was to investigate the structural modifications of collagen extracellular matrix of amniotic membrane upon interaction with two different antibiotics, frequently used in surgical and post- surgical procedure, respectively ciprofloxacin and gentamicin. (revmaterialeplastice.ro)
The colocalisation with laminin indicates a mechanism of interaction between smooth muscle cells and mast cells that may be important in the role of mast cells in the process of fibrosis. (bmj.com)

Most of the identified proteins are connected with the initial events of foreign body reaction towards biomaterial (coagulation cascade proteins, complement component, and inflammatory proteins). (ibecbarcelona.eu)

Gel)ma Laminin -UV/365 nm, low endotoxin features a ready-to-use bioink that is formulated for high cell viability, and printability and is designed for extrusion-based 3D bioprinting and subsequent 365 nm light crosslinking and a solution of Laminin to enhance the bioink. (sigmaaldrich.com)

There is growing evidence that the Dermal-Epidermal Junction (DEJ) and its proteins are a target of oxidative stress autophagy, matrix metalloproteinases, and senescence [6]. (heraldopenaccess.us)
Although these products help treat skin issues, niacinamide usually targets the collagen I and III proteins of the inner dermal layer of the skin that causes skin aging [9]. (heraldopenaccess.us)
showed that Linefade could significantly induce collagen IV in cell culture models of Human Dermal Fibroblasts (HDFs) and epidermal skin explants [8]. (heraldopenaccess.us)
This dual treatment of epidermal growth factors (EGFs) and fibroblast growth factors (FGFs) stimulate the production of laminin and fibronectin which are key structural components of the dermal junction. (dermaestheticsusa.com)
These proteins are involved in the anchoring of the epidermis to the dermis at the dermal junction resulting in less sagging and drooping of the skin. (dermaestheticsusa.com)

The expression of recombinant human COL4A1 protein includes the construction of the expression vector containing the recombinant DNA and the transformation of the expression vector into the E.coli, which provides a variety of macromolecules and components required for transcription and translation. (cusabio.com)
The recombinant DNA was formed by fusing the N-terminal GST tag sequence to the designated sequence encoding the 30-167aa of the human COL4A1 protein. (cusabio.com)
Under SDS-PAGE condition, this recombinant COL4A1 protein migrated to the band of about 40 kDa molecular weight. (cusabio.com)

Indirect measurements, analyze the assessment of parameters that are linked to the biomechanical properties of the skin and give information on: Collagen, Face analysis and volume, molecular composition, proteomics and metagenomics, dermis size and shape, Skin aspect and structure. (premiumbeautynews.com)

2. The laminins forms networks that remain in close association with cells through interactions with cell surface receptors. (premiumbeautynews.com)

We observed substantial brain pathology in SARS-CoV-2-infected dogs, particularly involving blood-brain barrier damage resembling small vessel disease, including changes in tight junction proteins, reduced laminin levels, and decreased pericyte coverage. (cdc.gov)

Hair is a protein filament that grows through the epidermis from follicles deep within the dermis. (natmedworld.com)
Collagen IV is a known significant anchoring protein found in the lamina densa region of the DEJ that provides a framework to the interconnecting network of dermis-epidermis. (heraldopenaccess.us)

We demonstrated adhesive and significant pathogen inhibitory efficacies among the swine intestinal L. amylovorus strains studied, pointing to their potential use as probiotic feed supplements, but no independent role could be demonstrated for the major S-layer proteins in adherence to epithelial cells. (biomedcentral.com)

The composite can present whole-molecule ECM proteins to cells, even those that do not spontaneously form hydrogels ex vivo, in 3D. (umn.edu)
Tested in an ex vivo model of corticoid-induced skin aging, the EGF/FGF Marvel Serum stimulated the expression of collagen VII and laminin-5. (dermaestheticsusa.com)

Substrate-bound factor(s) from central nervous system-conditioned media also had a synergistic effect with laminin, suggesting a possible cooperation between humoral proteins and nervous system extracellular matrix. (nature.com)

Mass spectrometry based proteomic analyses identified 25 proteins (having at least two peptide sequences detected) in the scaffolds generated with an enzymatic approach, 143 with the detergent approach, and 102 with the solvent approach, as compared to 155 detected in unprocessed native human fat. (psu.edu)

It contains melanocytes, cells that produce the protein pigment melanin which determines skin colour. (natmedworld.com)
Vitamin B3 - A powerful antioxidant with anti-carcinogenic qualities believed to inhibit the harmful effects of ultra violet rays, help even skin tone & enhance collagen production. (chicagohealthfoods.com)
Currently, green cosmetic awareness has led to plant-based skin care products that include anti-aging properties and pharmacological actions such as anti-allergy, pro-collagen, anti-inflammatory and anti-carcinogenic, UV-protective [4]. (heraldopenaccess.us)
It enhances the performance of niacinamide-based skin formulations by acting synergistically and inducing collagen IV biosynthesis. (heraldopenaccess.us)
Collagen IV in the DEJ gets depleted as the non-photodamaged skin aging occurs chronologically [8]. (heraldopenaccess.us)
Derived from rice protein, this unique ingredient prevents collagen breakdown, delaying aging of skin. (remi-d.com)

Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request. (cusabio.com)
3] They are composed of a family of related proteins sharing common structural and sequence features. (pearltrees.com)
A single interruption was inserted concerning the 2 S. pyogenes collagen domains, incorporating both a 4-residue (GAAVM) or 15residue (GQISEQKRPIDVEFQK) interruption sequence through the a5 chain of form IV collagen. (dot1linhibitor.com)
A mutation launched close to an interruption sequence located inside style IV collagen also led to considerable delay in folding (Hwang and Brodsky, 2012). (dot1linhibitor.com)

The biological functions of Lactobacillus S-layer proteins (Slp:s) are not well understood. (biomedcentral.com)

BFPP patients have structural abnormalities of the cerebral cortex, cerebellum, and pons. (jneurosci.org)

TGF-β2 treatment upregulated the expression of Col1α1, Col4α2, FN, CTGF, TGM2, and TSP-1 mRNA and protein in cultured astrocytes. (arvojournals.org)
Both PWN loading and hypoxia enhanced tracheal elasticity and thickened the apical extracellular matrix (aECM) of the tracheal tubes while a notable upregulated expression of a resilin-like mucin protein Muc91C was observed at the aECM layer of PWN-loaded and hypoxic tracheal tubes. (elifesciences.org)
Unexpectedly, 3D engagement of ECM proteins also altered immunomodulatory function of MSCs in that expression of IL-6 gene was elevated relative to basal levels in 2D. (umn.edu)

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. (cusabio.com)

The results support a particular localisation of protein-bound amino acid residues and enzymatic catalytic activities indicative of organic secretion, possibly tissue kallikrein, in sublingual ductal cells of ferret. (bvsalud.org)
All mast cells in the muscularis propria were colocalised with patches of laminin. (bmj.com)

The complete taxonomic breakdown of all proteins with Int_alpha domain is also avaliable . (embl.de)

Five novel Lupinus albus MPIs were found and constitute the first reported protein inhibitors of metalloproteinases in plants and the first reported plant peptide inhibitors against a matrixin proteinase. (wikipedia.org)

Anatomy25

Organisms18

Diseases5

Chemicals and Drugs82

Analytical, Diagnostic and Therapeutic Techniques and Equipment19

Phenomena and Processes33

Disciplines and Occupations1

Technology, Industry, Agriculture1

Information Science3

Proteoglycans10

Extracellular matrix p2

Fibronectin and laminin1

Elastin6

Adhesion7

Peptides5

Basement membrane9

Fibril-forming c1

Subunit3

Integrins2

Proliferation2

Amino acids2

Connective tissue2

Anchoring fibrils2

Tissues7

Mutations3

Differentiation6

Outgrowth1

Type7

MMPs4

Meshwork1

Degrade2

Myosin1

Matrix proteins1

Biologically1

Epidermolysis bullosa2

Regenerative medicine2

High molecular weight2

Basal lamina1

Complex3

Contrast1

Bacterial3

Molecules2

Interaction3

Biomaterial1

Subsequent1

Dermal5

Recombinant3

Molecular1

Receptors1

Junction1

Epidermis2

Adherence1

Vivo2

Nervous system1

Sequences1

Skin6

Sequence4

Biological functions1

Abnormalities1

Expression3

Stability1

Cells2

Breakdown1

Found1