• Background: Elderly patients are at high risk for postoperative complications and increased mortality after hip fracture (HF) surgery due to frailty and co-morbidities. (elsevierpure.com)
  • Conclusions: Neither age, gender, NLR D 0 nor CRP D 0 are suitable parameters to predict postoperative, intra-hospital mortality in elderly patients undergoing surgery for HF. (elsevierpure.com)
  • However, nonoperative care of intertrochanteric fractures had significant, unacceptable morbidity and mortality because of concurrent medical problems and prolonged incumbency that prevented union from occurring. (medscape.com)
  • Therefore, progress in the care of intertrochanteric fractures has involved reducing the mortality from nonorthopedic coexisting or concurrent medical problems and decreasing the degree of malunion and possible nonunion of these fractures. (medscape.com)
  • In addition, postoperative care and rates of complications, including mortality and morbidity, vary for the different subcategories of intertrochanteric fractures. (medscape.com)
  • [ 2 , 3 , 4 ] The acceptable healing rates for nonsurgical management were accompanied by unacceptable morbidity and mortality because of frequent nonorthopedic complications associated with prolonged immobilization or inactivity, as well as malunions compromising patient function. (medscape.com)
  • Hip fractures are associated with considerable disability and reduced survival and, although they represent less than 20% of all osteoporotic fractures, they account for the majority of fracture-related health care expenditure and mortality in men and women over the age of fifty 1 . (aprifel.com)
  • The Impact of Hip Fracture on Geriatric Care and Mortality Among older Swedes: Mapping Care Trajectories and Their Determinants. (ki.se)
  • Hospital Length of Stay After Hip Fracture and It's Association With 4-Month Mortality-Exploring the Role of Patient Characteristics. (ki.se)
  • Comorbidity and the association with 1-year mortality in hip fracture patients: can the ASA score and the Charlson Comorbidity Index be used interchangeably? (ki.se)
  • Fatal PE may have an incidence of 2% after hip fracture and may contribute to illness and mortality in other cases. (wikipedia.org)
  • A matched patient analysis of early surgery (within 24 hours of ED arrival) vs. delayed surgery determined that patients undergoing early operation experienced lower 30-day mortality (5.8% vs 6.5%) and fewer complications (myocardial infarction, deep vein thrombosis, pulmonary embolism, and pneumonia). (the-hospitalist.org)
  • Wait time greater than 24 hours for adults undergoing hip fracture surgery is associated with an increased risk of 30-day mortality and complications. (the-hospitalist.org)
  • Association between wait time and 30-day mortality in adults undergoing hip fracture surgery. (the-hospitalist.org)
  • Hospitals with fracture liaison services also have lower mortality rates and patients spend fewer days in hospital. (newswise.com)
  • Geriatricians and orthopaedic surgeons worked together to manage older patients with hip fracture in order to minimise mortality and improve disease prognosis. (biomedcentral.com)
  • Mortality, disability, and nursing home use for persons with and without hip fracture: a population-based study. (cdc.gov)
  • Secondary outcomes were falls, major osteoporotic fractures, hip fractures and all-cause mortality. (cmaj.ca)
  • Is the higher mortality among men with hip fracture explained by sex-related differences in quality of in-hospital care? (bvsalud.org)
  • Association of anticholinergic drug use with postoperative mortality among patients with hip fracture. (bvsalud.org)
  • Prediction Ability of Charlson, Elixhauser, and Rx-Risk Comorbidity Indices for Mortality in Patients with Hip Fracture. (bvsalud.org)
  • OUTCOME MEASURES: Comparison of 30-day and 1 year mortality, co-morbidities, length of post-fracture hospital stay, specific complication rates and cognitive function between the hospital and control group. (wustl.edu)
  • These patients have increased mortality, with almost 50% dead within 1 year of the fall. (wustl.edu)
  • Venous thromboembolism (VTE) is major problem after hip fracture surgery with substantial morbidity and mortality. (springeropen.com)
  • Guidelines exist for the surgical treatment of hip fracture, but the effect of early surgery on mortality and other outcomes that are important for patients remains unclear. (cmaj.ca)
  • These studies had a total of 13 478 patients for whom mortality data were complete (1764 total deaths). (cmaj.ca)
  • Based on the five studies that reported adjusted risk of death (4208 patients, 721 deaths), irrespective of the cut-off for delay (24, 48 or 72 hours), earlier surgery (i.e., within the cut-off time) was associated with a significant reduction in mortality (relative risk [RR] 0.81, 95% confidence interval [CI] 0.68-0.96, p = 0.01). (cmaj.ca)
  • Among elderly patients, hip fracture is associated with a one-year mortality rate ranging from 14% to 36% 1 and also with profound temporary and sometimes permanent impairment of independence and quality of life. (cmaj.ca)
  • Current guidelines 4 indicate that surgery for hip fracture should be performed within 24 hours of injury, as earlier surgery has been associated with better functional outcome, shorter hospital stay, shorter duration of pain and lower rates of nonunion, postoperative complications and mortality. (cmaj.ca)
  • More specifically, we addressed the following question: Among patients 60 years of age or older who underwent surgery for hip fracture, what was the effect of early surgery, relative to delayed surgery, on all-cause mortality and postoperative complications? (cmaj.ca)
  • Studies fulfilling the following criteria were eligible for inclusion: target population consisting of patients 60 years of age or older who underwent surgery for a low-energy hip fracture, evaluation of preoperative surgical delay, consideration of all-cause mortality as an outcome and prospective design. (cmaj.ca)
  • Background: In this study, a retrospective evaluation was made of patients aged 70 years and over who were applied with proximal-femoral nail (PFN) or calcareous replacement cemented hemiarthroplasty in respect of early and late-stage morbidity and mortality and functional personal independence. (journaltocs.ac.uk)
  • Globally in both men and women, osteoporosis and osteoporotic fractures are important public health concerns because of related morbidity and mortality, 4,5 diminished health-related quality of life, 6,7 and associated costs. (ajmc.com)
  • Bretherton CP, Parker MJ (2015) Early surgery for patients with a fracture of the hip decreases 30-day mortality. (springer.com)
  • Mortality rates after hip fractures increase by up to 30% with age. (e-agmr.org)
  • Additionally, these patients with 30-day mortality had a significantly lower rate of surgical treatment (p=0.027) and a longer time from injury to surgery (p=0.014). (e-agmr.org)
  • From the early 1800s on, the literature revealed that intertrochanteric hip fractures routinely healed but were malunited in varus, leading to deformity and decreased function secondary to a limp and hip abductor weakness. (medscape.com)
  • The treatment of femoral neck fractures, intertrochanteric hip fractures, and most tension femoral neck stress fractures requires surgical intervention. (medscape.com)
  • Classification of intertrochanteric hip fractures is based on a system introduced by Evans in 1949. (medscape.com)
  • Intertrochanteric hip fractures have significant complication rates: 20-30% in the first year, including a 5% nonunion rate, a 5% infection rate, and an 11% rate of device failure. (medscape.com)
  • Medical complications of intertrochanteric hip fractures are secondary to any preexisting medical conditions that have or have not been recognized, diagnosed, or properly treated, depending on the limitations of time and facilities and the current level of medical care. (medscape.com)
  • Conclusions: Proximal femoral nailing can be one of the primary treatment options for intertrochanteric hip fractures in the elderly. (journaltocs.ac.uk)
  • From January 1, 2018, to April 30, 2023, 7,746 medical records were retrospectively collected for patients aged ≥ 65 years who were hospitalised for hip fracture in Beijing Jishuitan Hospital, Capital Medical University. (biomedcentral.com)
  • Patients aged 65 years and older who underwent femoral neck or intertrochanteric fracture surgery in our hospital from January 1, 2018, to April 30, 2023, and whose discharge diagnoses included acute cholecystitis were included in this retrospective analysis. (biomedcentral.com)
  • Starting from January 2023, we are looking at using similar 2D-to-3D reconstruction techniques to predict hip-related pathologies in kids during their development. (lu.se)
  • Did patients 70 years and older admitted to the ICU with COVID-19 have worse outcomes than elderly patients admitted to the ICU with other types of pneumonia? (medscape.com)
  • Newswise - There are significant variations in healthcare spending and care delivery across NHS hospitals in England and Wales following hip fracture, a new study aimed at understanding how hospital care impacts patients' outcomes and costs has revealed. (newswise.com)
  • The study, led by the University of Bristol and funded by Versus Arthritis , highlights the urgent need for evidence-based quality improvement strategies to reduce healthcare spending and improve patient outcomes in the year following a hip fracture. (newswise.com)
  • The study highlights the importance of addressing the way hospitals deliver hip fracture care to improve the effectiveness and efficiency of hip fracture services, and the need to develop evidence-based quality improvement strategies across the UK, to achieve financial savings while also improving patient outcomes. (newswise.com)
  • Celia Gregson , Professor in Clinical Epidemiology in the Musculoskeletal Research Unit at the University of Bristol and Chief Investigator of the study, commented, "The variation we have seen in patient outcomes and health spending following hip fracture are difficult to justify on purely clinical grounds, it tells us that the way we organise the delivery of care can be improved nationally. (newswise.com)
  • By prioritising orthogeriatrician assessment, getting patients out of bed promptly after surgery, providing seven-day physiotherapy, reducing delirium risk for patients, and holding monthly multidisciplinary clinical governance meetings, hospitals stand to improve patient outcomes and reduce their healthcare spending. (newswise.com)
  • Delay in adequate analgesia for hip fracture in geriatric patients leads to worse outcomes, including increased rate of delirium and increased hospital length of stay. (asra.com)
  • Long-term management of patients with hyperthyroidism requires careful consideration of the likely outcomes of treatment including the risk of hypothyroidism. (racgp.org.au)
  • Investigators confirmed the primary outcomes for the analysis were overall fractures, consisting of vertebral, hip, humerus, and distal radius fractures. (hcplive.com)
  • Bergqvist J, Iderberg H, Mesterton J, Bengtsson N, Wettermark B, Henriksson R. Healthcare resource use, comorbidity, treatment and clinical outcomes for patients with primary intracranial tumors: a Swedish population-based register study. (janusinfo.se)
  • Sveréus S, Larsson K, Rehnberg C. Clinic continuity of care, clinical outcomes and direct costs for COPD in Sweden: a population based cohort study. (janusinfo.se)
  • Evans M, Carrero JJ, Bellocco R, Barany P, Qureshi AR, Seeberger A, Jacobson SH, Hylander-Rössner B, Rotnitzky A, Sjölander A. Initiation of erythropoiesis-stimulating agents and outcomes: a nationwide observational cohort study in anaemic chronic kidney disease patients. (janusinfo.se)
  • Time in Therapeutic Range and Outcomes After Warfarin Initiation in Newly Diagnosed Atrial Fibrillation Patients With Renal Dysfunction. (janusinfo.se)
  • BACKGROUND: Large regional hospitals achieve good outcomes for patients with complex conditions. (ox.ac.uk)
  • OBJECTIVE: To test the hypothesis that older adults with isolated hip fractures experience delayed surgical treatment and worse clinical outcomes when treated in higher-level trauma centers. (ox.ac.uk)
  • The aim is to gain perspective on the many decisions that have, or have not, been taken that affect the outcomes for nursing education and, ultimately, patient care. (nzno.org.nz)
  • To measure the prevalence, predictors, and posthospitalization outcomes associated with the overlap syndrome of coexisting depression and incident delirium in older hospitalized patients. (nzno.org.nz)
  • Efforts to identify, prevent, and treat this condition may reduce the risk of adverse outcomes in older hospitalized patients. (nzno.org.nz)
  • The data looked at the effect of a sliding hip screw versus cancellous screws on the risk of reoperation and other key outcomes. (aaos.org)
  • Concurrently, the researchers led a trial comparing patient outcomes between hemiarthroplasty - a surgical procedure that involves replacing half of the hip joint - and total hip arthroplasty for displaced femoral neck fractures in patients 65 years and older. (aaos.org)
  • Overall, there was greater symptom relief and better quality of life outcomes for patients who underwent surgery compared with medical treatment. (primeinc.org)
  • Hospitalized non-COVID patients experienced worse outcomes during the peaks of the pandemic compared to the nadirs and the preceding year, perhaps due to the limited availability of resources. (ima.org.il)
  • Yoshioka R, Yamamoto S, Nakatani E, Yasui-Furukori N. Effectiveness of suvorexant versus benzodiazepine receptor agonist sleep drugs in reducing the risk of hip fracture: Findings from a regional population-based cohort study. (jmir.org)
  • 1 Given this gap in data, Shin and colleagues conducted a nationwide, population-based cohort study to separately compare SGLT2 inhibitors with incretin-based drugs in 2 independent cohorts: SGLT2 inhibitors vs. DPP4i and SGLT2 vs. GLP-1 RA. (hcplive.com)
  • A population-based cohort study. (bvsalud.org)
  • Forslund T, Wettermark B, Andersen M, Hjemdahl P. Stroke and bleeding with NOAC or warfarin treatment in patients with non-valvular atrial fibrillation: a population based cohort study. (janusinfo.se)
  • Eriksson I, Cars T, Piehl F, Malmström R, Wettermark B, von Euler M. Persistence with dimethyl fumarate in relapsing-remitting multiple sclerosis: a population based cohort study. (janusinfo.se)
  • Acromegaly leads to various skeletal complications, and fragility fractures are emerging as a new concern in patients with acromegaly. (e-enm.org)
  • GH hypersecretion and the resultant overproduction of IGF-1 lead to numerous musculoskeletal complications of acromegaly, including acral enlargement, carpal tunnel syndrome, osteoarthritis, and vertebral fractures [ 4 , 5 ], highlighting the clinical importance of bone health in patients with acromegaly. (e-enm.org)
  • Complications associated with poorly treated or misdiagnosed stress fractures are considerable. (medscape.com)
  • Although abdominal complications are rare in patients with hip fracture and hip surgery, the intermittent occurrence of acute cholecystitis prompted us to study the incidence of acute cholecystitis in this particular group of patients. (biomedcentral.com)
  • The most common cause of death after a fall was complications from a hip fracture. (cdc.gov)
  • There was no statistical difference between post-operative complications or length of stay post-fracture. (wustl.edu)
  • Local orthopedic complications can occur if an adequate stable reduction of the fracture is not obtained and maintained or if the correct position is lost before healing because of movement associated with daily activities and personal hygiene. (medscape.com)
  • We conducted a systematic review and meta-analysis to determine the effect of early surgery on the risk of death and common postoperative complications among elderly patients with hip fracture. (cmaj.ca)
  • Proponents of early treatment argue that this approach minimizes the length of time a patient is confined to bed rest, thereby reducing the risk of associated complications, such as pressure sores, deep vein thrombosis and urinary tract infections. (cmaj.ca)
  • 8 However, those favouring a delay believe it provides the opportunity to optimize patients' medical status, thereby decreasing the risk of perioperative complications. (cmaj.ca)
  • In addition to recommending annual vaccination, primary care providers might encourage sufficient sleep and adequate physical activity-especially among patients who have increased risk for influenza complications and are less likely to achieve these behaviors. (cdc.gov)
  • These fractures decrease quality of life, was not good enough for evaluation and adding to age-related complications with they were discarded. (who.int)
  • A total of 71 patients were treat complications of osteoporosis rather excluded from the study: 21 had malignant than osteoporosis itself [ 6 ]. (who.int)
  • Materials and Methods: This observational cohort study based on the Swedish Arthroplasty Register (SAR) compared 2242 patients with dual mobility cups (DMC) and 6726 with conventional total hip arthroplasty (cTHA), all due to acute fracture 2005-2019. (lu.se)
  • However, Shin and colleagues noted, to their knowledge, that no observational studies have assessed the association between their use and fracture risk in postmenopausal individuals with T2D. (hcplive.com)
  • Hip fractures after falls in hospital: a retrospective observational cohort study. (wustl.edu)
  • DESIGN: Retrospective observational cohort study. (wustl.edu)
  • We conducted a retrospective observational cohort study at a tertiary medical center in Israel. (ima.org.il)
  • Objective To examine the fracture risk with use of disease-modifying antirheumatic drugs (DMARDs), statins, proton pump inhibitors (PPIs), opioids, non-opioid analgesics and psychotropic medications in a US-wide observational rheumatoid arthritis (RA) cohort. (bmj.com)
  • Methods Patients with RA without prior fracture from 2001 through 2017 in FORWARD, a longitudinal observational registry, were assessed for osteoporosis-related site fractures (vertebra, hip, forearm and humerus). (bmj.com)
  • This study suggests that BMD thresholds for drug therapy to prevent osteoporotic fracture should be only modestly adjusted in those with prior wrist fracture compared with those without prior wrist fracture. (healthpartners.com)
  • The primary outcome was a composite of fall or major osteoporotic fracture within 90 days of first prescription. (cmaj.ca)
  • To examine healthcare resource utilization (HRU) and costs in a population of managed care enrollees who experienced an osteoporotic fracture. (ajmc.com)
  • To prevent this, the diagnosis of osteoporosis following an osteoporotic fracture is important. (e-jbm.org)
  • Therefore, this study aimed 1) to evaluate the rate of BMD measurement after osteoporotic fracture in the Korean population, and 2) to determine whether the rate of BMD measurement after osteoporotic fracture changed between 2005 and 2010. (e-jbm.org)
  • 1 2 ] Osteoporosis results in osteoporotic fracture in hip, spine, humerus, and wrist. (e-jbm.org)
  • It is well-known that patients with an osteoporotic fracture have higher risk of a subsequent fracture than those with no previous fracture. (e-jbm.org)
  • 6 7 ] That is osteoporotic fracture offers physicians an important opportunity to initiate secondary prevention. (e-jbm.org)
  • There were few studies on the rate of BMD measurement after osteoporotic fracture in Korea, and whether there was a change of rate of BMD measurement after fractures. (e-jbm.org)
  • We analyzed patients aged over 50 years who were diagnosed with osteoporotic fracture by physician at 2005 and 2010. (e-jbm.org)
  • Methods: A single-centre retrospective cohort study was performed in 782 patients who were operated on for HF. (elsevierpure.com)
  • Methods: A prospective cohort follow-up study of 390 hip fracture patients aged 65years and older was carried out. (vu.nl)
  • MATERIALS AND METHODS: We ascertained prior history of wrist fracture since age 50, measured calcaneal and hip BMD, and performed lateral spine films in a cohort of 9704 elderly community-dwelling women, and then followed them prospectively for incident vertebral and hip fractures. (healthpartners.com)
  • METHODS: We conducted a population-based parallel cohort study using data from the Sistema d'Informació per al Desenvolupament de la Investigació en Atenció Primària (SIDIAP) database. (ox.ac.uk)
  • Methods: The study was carried out with 50 patients operated on by the main author, who were randomly divided into two groups, experimental and control. (journaltocs.ac.uk)
  • Methods: The study included a total of 77 patients aged over 70 years with an AO type 31-A1 or 31-A2 fracture. (journaltocs.ac.uk)
  • This requires to build more robust methods that encompass the large variability of hip anatomy during growth, and the development of quantitative methods that can support the doctors in their clinical decision-making for each patient. (lu.se)
  • A total of 931 patients with acromegaly who had never used an osteoporosis drug before and were treated with surgery alone were selected as study participants, and a 1:29 ratio of 26,999 age- and sex-matched osteoporosis drug-naïve controls without acromegaly were randomly selected from the database. (e-enm.org)
  • The other problem related to intertrochanteric fractures is the associated osteoporosis or osteopenia seen in the aging population. (medscape.com)
  • Osteoporosis is a major public health concern and hip fractures are an oftentimes life-changing consequence of osteoporosis. (ki.se)
  • With a focus on hip fractures, our work covers different aspects of fragility fracture risk, prognosis after fragility fractures, as well as the treatment of osteoporosis. (ki.se)
  • Hip fracture is a proxy measure for osteoporosis. (cdc.gov)
  • Because osteoporosis is a chronic disease, years might pass before changes in patient behavior or clinical practice affect hospitalization for hip fracture. (cdc.gov)
  • All-cause and osteoporosis-related HRU and costs were analyzed in patients 50 years and older with a qualifying index fracture and continuous enrollment with medical and pharmacy benefits for 12 months preindex (baseline period). (ajmc.com)
  • This retrospective database study identified increased healthcare resource utilization and significant economic burden for both all-cause and osteoporosis-related healthcare costs during the 12 months following index fracture. (ajmc.com)
  • The current findings suggest a need for better management of fragility fractures to reduce osteoporosis cost of illness. (ajmc.com)
  • Osteoporosis is characterized by compromised bone strength due to loss of bone mass and deterioration of bone quality, resulting in increased fracture risk. (ajmc.com)
  • Our results showed that about half of all patients with osteoporotic fractures had BMD measurement, and that screening for osteoporosis in patients with osteoporotic fractures increased between 2005 and 2010. (e-jbm.org)
  • Bone mineral density (BMD) measurement is the first important step to investigate and manage patients with osteoporosis. (e-jbm.org)
  • Fragility fractures, broken bones related to osteoporosis, affect more than 2 million people over the age of 50 in the US each year. (uchicagomedicine.org)
  • In addition, older adults are more likely than younger adults to experience fractures after low-energy trauma due to osteoporosis, which is more common in postmenopausal women. (e-agmr.org)
  • Among studies on the incidence of hip fractures and prevalence of osteoporosis in Turkey, the FRACTURK study in 2011 reported that the incidence of hip fractures increased with age. (e-agmr.org)
  • In only 37.8% of the radiographs with fractures was a vertebral fracture highlighted in the radiologist's report, and only 13.2% of the women with vertebral fractures were on antiresorptive therapy for osteoporosis. (who.int)
  • A.H.G. and H.S.). The radiographs were white women in the USA have osteoporosis, then jointly reviewed with the principle au- of whom 25% have a vertebral fracture [ 3 ]. (who.int)
  • We have been focusing for many years on improving osteoporosis diagnosis and fracture risk assessment. (lu.se)
  • Incident type 2 diabetes and hip fracture risk: a population-based matched cohort study. (ox.ac.uk)
  • Therefore, this study investigated the risk of fractures in Korean patients with acromegaly. (e-enm.org)
  • Variation in care for patients presenting with hip fracture in six high-income countries: A cross-sectional cohort study. (medscape.com)
  • A total of 142,018 individuals (among which 116,509 women), aged ≥60 years old, from five prospective cohorts with relevant data participating in CHANCES: European Prospective Investigation into cancer and Nutrition ( EPIC )-Elderly Greece and EPIC -Elderly Umea from Sweden, the Swedish Mammography Cohort (SMC) and the Cohort Of Swedish Men (COSM) studies and the Nurses' Health Study (NHS) from US were included in the study. (aprifel.com)
  • Trends in Hip Fracture Incidence, Recurrence, and Survival by Education and Comorbidity: A Swedish Register-based Study. (ki.se)
  • Obesity Paradox" Holds True for Patients with Hip Fracture: A Registry-Based Cohort Study. (ki.se)
  • The role of having children for the incidence of and survival after hip fracture - A nationwide cohort study. (ki.se)
  • A nested case-control study was conducted using the General Practice Research Database (1987-2003), which contains information on patients in the United Kingdom. (nih.gov)
  • The study cohort consisted of users of PPI therapy and nonusers of acid suppression drugs who were older than 50 years. (nih.gov)
  • This study aims to determine a time to surgery threshold for hip-fracture surgery. (the-hospitalist.org)
  • Of the 42,230 adult patients in this study, 14,174 (33.6%) received hip-fracture surgery within 24 hours of emergency department arrival. (the-hospitalist.org)
  • Two-thirds of patients in this study surpassed this threshold. (the-hospitalist.org)
  • This study highlights the high healthcare burden associated with breaking a hip. (newswise.com)
  • Dr Rita Patel , Senior Research Associate in Medical Statistics at Bristol and statistician for the study, added: "If a consultant orthogeriatrician attends hospital clinical governance meetings, a further cost saving of £356 per patient could potentially be achieved, as well as patients spending fewer days spent in the hospital in the year following hip fracture. (newswise.com)
  • Our study suggests that rather than increasing the burden on the NHS, providing additional care for patients with orthogeriatrician and fracture liaison services may actually improve NHS efficiency. (newswise.com)
  • A study by Shin and Gillingham classified stress fractures based primarily on MRI findings. (medscape.com)
  • UNLABELLED: In this large prospective cohort study of elderly women, the relationships between prior wrist fracture and incident hip and radiographic vertebral fractures were significantly attenuated when adjusted for BMD. (healthpartners.com)
  • Langade D, Thakare V, Kanchi S, Kelgane S. Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study. (jmir.org)
  • Phase II - parallel-group, randomised (using a dynamic adaptive algorithm) feasibility study with focus groups and an anonymised cohort study.SettingRecruitment was from orthopaedic wards of three acute hospitals in the Betsi Cadwaladr University Health Board, North Wales. (lancs.ac.uk)
  • Compared with the cohort study, a younger, healthier subpopulation was recruited. (lancs.ac.uk)
  • To ascertain the clinical utility and sustained benefits of the commonly used 80% pain reduction threshold following two comparative medial branch blocks prior to RFA, researchers conducted a telephone survey study of 85 patients from one institution. (asra.com)
  • RESULTS: During the study period (median follow-up 2.63 years), 444/58,483 diabetic patients sustained a hip fracture (incidence rate 2.7/1,000 person-years) compared to 776/113,448 matched controls (2.4/1,000). (ox.ac.uk)
  • This is the first study on the characteristics of acute cholecystitis in older patients with hip fracture in China. (biomedcentral.com)
  • Patients were followed up from the index date until the earlier outcome occurrence, drug discontinuation (90-day grace period), switch, death, or end of the study period. (hcplive.com)
  • Similar trends for the secondary outcome were identified across both study cohorts where SGLT2 inhibitors did not increase the risk of fractures, regardless of the comparator drug. (hcplive.com)
  • Effect of birth cohort on risk of hip fracture: age-specific incidence rates in the Framingham Study. (cdc.gov)
  • Parkkari J, Kannus P, Palvanen M, Natri A, Vainio J, Aho H, Vuori I, Järvinen M. Majority of hip fractures occur as a result of a fall and impact on the greater trochanter of the femur: a prospective controlled hip fracture study with 206 consecutive patients. (cdc.gov)
  • The study cohort included adults with dementia (excluding patients with chronic psychotic illnesses) living in long-term care and aged 66 years and older. (cmaj.ca)
  • A nationwide cohort study. (bvsalud.org)
  • OBJECTIVE: The main objective of this study was to investigate whether type 2 DM produces a higher prevalence of vertebral, hip and non-vertebral fractures in obese postmenopausal Caucasian women. (who.int)
  • METHOD: This study was a prospective cohort of 111 patients with type 2 DM and 91 control individuals (CTR) over age 65 and obese, recruited from 16 centers in Spain. (who.int)
  • Comanagement of geriatric patients with hip fractures: a retrospective, controlled, cohort study. (medscape.com)
  • This study aimed to assess the postoperative compliance of thromboprophylaxis in elderly patients undergoing hip fracture surgery and to confirm the correlation between compliance and VTE risk. (springeropen.com)
  • This retrospective cohort study included consecutive elderly hip fracture patients who undergoing surgery. (springeropen.com)
  • Between 2008 and 2012, 1214 eligible patients were included in this study. (springeropen.com)
  • In this study we found fewer than 1 in 5 patients maintained compliant with thromboprophylaxis guidelines after discharge following hip surgery. (springeropen.com)
  • Thus the aim of this study was to assess the prevalence of thromboprophylaxis compliance and its impacts on the rate of VTE after surgery of hip fracture within 6weeks. (springeropen.com)
  • The cohort study was a secondary analysis of the Program of Randomized Trials to Evaluate Preoperative Antiseptic Skin Solutions in Orthopedic Trauma (PREP-IT) program. (consultantlive.com)
  • In the current retrospective cohort study, all patients included in the PREP-IT program sustained an open fracture, femur fracture, or hip fracture. (consultantlive.com)
  • The study included a total of 3598 patients. (consultantlive.com)
  • Although the COVID-19 pandemic has created unprecedented challenge to health care systems far and wide, this cohort study suggests that hospital systems throughout the US and Canada were able to effectively mitigate these challenges such that 24-hour time-to-surgery benchmarks were unchanged from before the pandemic to after the pandemic," investigators wrote. (consultantlive.com)
  • The study, " Association of COVID-19 With Achieving Time-to-Surgery Benchmarks in Patients With Musculoskeletal Trauma ," was published in JAMA Health Forum . (consultantlive.com)
  • HIV-infection and psychiatric illnesses - A double edged sword that threatens the vision of a contained epidemic: The Greater Stockholm HIV Cohort Study. (janusinfo.se)
  • People with both HIV and hepatitis C are more likely to sustain hip or spine fractures than people with one or none of these viruses, according to a study of nearly 39,000 Medicaid recipients presented at CROI 2011. (hivandhepatitis.com)
  • Casuistry was determined by pilot study with the first five patients of each group. (journaltocs.ac.uk)
  • Retrospective cohort study using the Optum Research Database (January 2007 to May 2017). (ajmc.com)
  • Enocson A, Tidermark J, Tornkvist H, Lapidus LJ (2008) Dislocation of hemiarthroplasty after femoral neck fracture: better outcome after the anterolateral approach in a prospective cohort study on 739 consecutive hips. (springer.com)
  • RESEARCH DESIGN: Retrospective cohort study using a statewide longitudinal database that captured 98% of inpatients within California (2007-2011). (ox.ac.uk)
  • Prospective cohort study. (nzno.org.nz)
  • However, no data is currently available on this issue in mainland China, we therefore assessed the risk of hip fracture after new-onset stroke using a cohort study. (biomedcentral.com)
  • In this study, we investigated the effect of new-onset stroke on the risk of HF in the Chinese population based on data from the Kailuan Cohort Study [ 11 ]. (biomedcentral.com)
  • The rationale for the Kailuan Cohort Study and its design and methodology have been described in detail elsewhere [ 12 ]. (biomedcentral.com)
  • In a study comparing esomeprazole with ranitidine for 6 months, 80.2% of patients (n = 1,902) taking the PPI esomeprazole 20 mg once daily continuously significantly improved all symptoms, compared with 47.0% of patients taking ranitidine 150 mg twice daily continuously. (primeinc.org)
  • The aim of the study was to investigate the effects of health education given by nurses to patients with COPD on the daily oxygen concentrator (OC) usage time. (mdpi.com)
  • During the study period, about half of all patients with osteoporotic fractures had BMD measurement. (e-jbm.org)
  • Our study prospectively examined patients with hip fracture aged 65 years and over who applied to the Atatürk University Medical Faculty Hospital Orthopedics Service in 2020-2021. (e-agmr.org)
  • The 120 patients included in the study had a mean age of 79.71±7.27 years, and 51.7% were female. (e-agmr.org)
  • It is, however, reassuring from the results of a recent study in a 7-year real-life cohort that no patients discontinued entecavir because of the occurrence of drug-related side effects. (medscape.com)
  • She has collaborated in research projects including the Tehran lipid and glucose prospective cohort study and clinical trials. (who.int)
  • ABSTRACT The study aimed to determine hospital-based prevalence of vertebral fractures in post- menopausal Saudi Arabian women. (who.int)
  • Elderly patients frequently have other significant coexisting or preexisting pathologic conditions that reduce their ability to resist the stresses of anesthesia, trauma, and surgery and increase their need for extensive postoperative rehabilitation. (medscape.com)
  • Earlier surgery was associated with a lower risk of death and lower rates of postoperative pneumonia and pressure sores among elderly patients with hip fracture. (cmaj.ca)
  • The use of sodium-glucose cotransporter-2 (SGLT2) inhibitors was associated with a similar risk of fracture as incretin-based drugs among postmenopausal individuals with type 2 diabetes (T2D) , according to new research. (hcplive.com)
  • A heightened risk of fractures in postmenopausal individuals with T2D has been linked to the interaction of elevated blood glucose levels and declining estrogen levels due to menopause. (hcplive.com)
  • The classic clinical presentation of a hip fracture is an elderly patient who sustained a low-energy fall and now has groin pain and is unable to bear weight. (wikipedia.org)
  • Background Proximal femoral fracture is a major health problem in old age, with annual UK health and social care costs of £2.3B. Rehabilitation has the potential to maximise functional recovery and maintain independent living, but evidence of clinical effectiveness and cost-effectiveness is lacking. (lancs.ac.uk)
  • The intervention was delivered in the community following hospital discharge.ParticipantsOlder adults (aged ≥ 65 years) who had received surgical treatment for hip fracture, lived independently prior to fracture, had mental capacity (assessed by the clinical team) and received rehabilitation in the North Wales area. (lancs.ac.uk)
  • While the net clinical benefit favours an initial two-drug therapy, physicians should be vigilant in relation to vulnerable patients and individualise therapy accordingly. (escardio.org)
  • As the National Centre for Orthopaedics, we believe that summarising and sharing the clinical characteristics of perioperative acute cholecystitis in older patients with hip fracture in our hospital is representative and necessary. (biomedcentral.com)
  • These findings indicate that SGLT2i has either similar or lower risks of fractures than incretin-based drugs even in a population at higher risk for fractures, providing reassurance to and helping health care professionals with their clinical decision-making," wrote the investigative team, led by Ju-Young Shin, PhD, School of Pharmacy, Sungkyunkwan University. (hcplive.com)
  • 2012 ). Several clinical studies and meta-analyses have shown that extended chemoprophylaxis significantly reduces the incidence of symptomatic DVT in orthopedic surgery patients (Fisher et al. (springeropen.com)
  • Conclusions Long-term safety profile of nucleoside analogues is now better defined with more data from large real-life cohorts and clinical trials with long-term follow-up. (medscape.com)
  • As a result, for adult patients (age 18 and over), along with every measured serum creatinine, most clinical labs now report an estimated GFR (eGFR). (medscape.com)
  • Conclusions: As treatment of acute femoral neck fractures, total hip arthroplasty with a dual mobility cup have similar outcome in terms of revisions in general, and due to dislocation or infections specifically, as one with conventional bearing. (lu.se)
  • New oral anticoagulants are recommended, but LMWH are suggested as the preferred option for patients undergoing total hip arthroplasty (THA) or total knee arthroplasty (TKA) (Francis 2013 ). (springeropen.com)
  • Burgers PT, Van Geene AR, Van den Bekerom MP, Van Lieshout EM, Blom B, Aleem IS, Bhandari M, Poolman RW (2012) Total hip arthroplasty versus hemiarthroplasty for displaced femoral neck fractures in the healthy elderly: a meta-analysis and systematic review of randomized trials. (springer.com)
  • CONCLUSION: In elderly women, prior wrist fracture is a risk factor for radiographic vertebral fracture independent of BMD. (healthpartners.com)
  • Statins (0.77 (0.62 to 0.96)) and TNFi (0.72 (0.54 to 0.97)) were associated with reduction in vertebral fracture risk only. (bmj.com)
  • 7 ], their diagnosis and management is viewed for the presence of vertebral fracture delayed until a visible limb fracture occurs. (who.int)
  • Conclusions: The risk not to regain prefracture mobility is highest in mobile patients without an aid. (vu.nl)
  • CONCLUSIONS: Newly diagnosed T2DM patients are at a 20% increased risk of hip fracture even in early stages of disease, but no for all fractures. (ox.ac.uk)
  • CONCLUSIONS: Older adults with hip fractures may be disadvantaged in L1TCs. (ox.ac.uk)
  • Current treatment of intertrochanteric fractures involves surgical intervention. (medscape.com)
  • Currently, with a few exceptions, surgical intervention is used to treat essentially all trochanteric fractures and is described as open reduction and internal fixation (ORIF). (medscape.com)
  • The operative treatment of tension stress fractures and hip fractures is discussed in Surgical Intervention. (medscape.com)
  • Objectives To develop an enhanced community-based rehabilitation package following surgical treatment for proximal femoral fracture and to assess acceptability and feasibility for a future definitive randomised controlled trial (RCT) and economic evaluation. (lancs.ac.uk)
  • A patient-centred choice of treatment modality should be individualised, taking into consideration the underlying pathology, age, sex, patient preference and availability of expert thyroid surgical care. (racgp.org.au)
  • Surgical management of hip fractures: an evidence-based review of the literature. (medscape.com)
  • When considering surgical treatment, individualizing risk assessment is particularly important, as older patients can present with very different health profiles. (stanford.edu)
  • however, in patients with advanced osteoarthrosis, such maintenance increases the surgical time. (journaltocs.ac.uk)
  • Clifton R, Haleem S, Mckee A, Parker MJ (2008) Closed suction surgical wound drainage after hip fracture surgery: a systematic review and meta-analysis of randomised controlled trials. (springer.com)
  • Rosemont, Ill. (February 5, 2020) - The 2020 Kappa Delta Ann Doner Vaughn Award will be presented to Marc Swiontkowski, MD, at this year's upcoming Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) in Orlando, Fla. for his research in the operative management of hip fractures, which identified the optimal surgical approach, helping to improve patients' lives. (aaos.org)
  • This unique technology helps surgeons provide a personalized surgical experience where each surgical plan is based on a patient-specific diagnosis and anatomy. (uchicagomedicine.org)
  • Hip fractures constitute a major and growing public health problem among older adults worldwide. (aprifel.com)
  • Hip fracture is a serious health concern, with more than 70,000 older adults admitted to a UK hospital each year. (newswise.com)
  • Our objective was to describe the comparative risk of falls and fractures among older adults with dementia dispensed trazodone or atypical antipsychotics. (cmaj.ca)
  • Are Older Adults With Hip Fractures Disadvantaged in Level 1 Trauma Centers? (ox.ac.uk)
  • SUBJECTS: All older adults (aged 65 y and above) admitted with an isolated hip fracture who did not require interhospital transfer. (ox.ac.uk)
  • Data from 7 case-control studies and 2 cohort studies included in the AHRQ review illustrated a potential association between PPI use for longer than 1 year and an increased risk for hip fractures in older adults (≥45 years of age). (primeinc.org)
  • However, older adults seem to compensate for decreased lower calf power by using their hip flexor and extensor muscles more than young adults. (msdmanuals.com)
  • Using the database of the Health Insurance Review Assessment Service (HIRA), we identified patients with osteoporotic fractures (hip, spine, humerus, and wrist fractures) in 2005 and 2010. (e-jbm.org)
  • We identified patients with hip, spine, humerus and wrist fractures on 2005 and 2010. (e-jbm.org)
  • 18% were of wrist fractures and more than twice that in females above the age of 50 years. (who.int)
  • The multivariate analysis showed that non-compliance was an independent risk factor of suffering VTE undergoing hip fracture surgery. (springeropen.com)
  • 2012 ). In 2012, American College of Chest Physicians guidelines on antithrombotic and thrombolytic therapy were published (ACCP9), and it was recommended that anticoagulant should be used in patients undergoing hip fracture surgery for at least 10-14days postoperatively, but preferably for as much as 28-35days (Falck-Ytter et al. (springeropen.com)
  • A hip fracture is a break that occurs in the upper part of the femur (thigh bone), at the femoral neck or (rarely) the femoral head. (wikipedia.org)
  • Femoral head fractures are a rare kind of hip fracture that may also be the result of a fall but are more commonly caused by more violent incidents such as traffic accidents. (wikipedia.org)
  • Avascular necrosis of the femoral head occurs frequently (20%) in intracapsular hip fractures, because the blood supply is interrupted. (wikipedia.org)
  • In this classification, the fracture prognosis is dependent on the location of the injury and its interference with the blood flow to the femoral head. (medscape.com)
  • Dolatowski FC, Adampour M, Frihagen F, Stavem K, Erik Utvåg S, Hoelsbrekken SE (2016) Preoperative posterior tilt of at least 20° increased the risk of fixation failure in Garden-I and -II femoral neck fractures. (springer.com)
  • If necessary, the surgeon modifies the preoperative plan to help control important measures of hip stability. (uchicagomedicine.org)
  • These findings derived after controlling for important potential confounders such as physical activity, body mass index, alcohol and energy intake, smoking and parameters of socio-economic status, were consistent across the cohorts and were more evident among women. (aprifel.com)
  • Dr Petra Baji , Senior Research Associate in Health Economics at Bristol Medical School: Translational Health Sciences (THS) and the paper's first author, explained: "The findings suggest that having all patients assessed by an orthogeriatrician within the first days of admission could cut healthcare spending by £529 per patient, as well as reduce the chance of dying by 15% in the year following hip fracture. (newswise.com)
  • The findings show that older people have a high chance of dying within a year of a hip fracture, and that quality of care varies hugely between NHS hospitals in England and Wales. (newswise.com)
  • In general, vasculitis is not commonly observed in GI biopsies of patients with IgA vasculitis (HSP), and the spectrum of findings includes neutrophilic infiltrate within the small bowel and colon, with the duodenum most commonly affected. (stanfordchildrens.org)
  • Based on these findings, the researchers concluded, 'Antiretroviral-treated HIV/HCV coinfected patients experienced increased rates of hip fractures compared to HCV monoinfected, antiretroviral-treated HIV monoinfected, and uninfected persons. (hivandhepatitis.com)
  • These findings suggest a significant economic burden associated with fractures, including a high total all-cause cost of care. (ajmc.com)
  • These findings highlight the need for effective fracture prevention strategies in patients at high risk of fracture. (ajmc.com)
  • In trial research published in The Lancet in 2017, patients aged 50 years and older with a low-energy hip fracture requiring fracture fixation were enrolled. (aaos.org)
  • 3 Notably, the majority of hip fractures were related to falling sideways onto the hip. (cdc.gov)
  • The majority of hip fractures after falls occur in medical or geriatric wards, but the highest risk group appears to be elderly patients on psychiatric wards. (wustl.edu)
  • High fruit and vegetable (F&V) intake has been associated with increased bone mineral density, decreased bone loss and reduced bone turnover, as well as, reduced incidence of hip fractures and fractures in other sites 2-4 . (aprifel.com)
  • Pre-fracture health differences reflect survival and functional outcome. (ki.se)
  • It consisted of a patient-held information workbook, a goal-setting diary and six additional therapy sessions.Main outcome measuresThe primary outcome measure was the Barthel Activities of Daily Living (BADL) index. (lancs.ac.uk)
  • Outcome measurements included Numerical Rating Scale (NRS), Patient Global Impression of Change (PGIC), and report of 50% or more reduction of index pain. (asra.com)
  • Further studies with high external validity are needed regarding total dislocation rate, patient-reported outcome, cost-effectiveness and learning curve, to make a definitive recommendation on the use of DMC for fracture cases. (lu.se)
  • Main outcome was incident hip fracture in 2006-2011, ascertained using the tenth edition of the International Classification of Diseases (ICD-10) codes. (ox.ac.uk)
  • MAIN OUTCOME MEASURES: Lateral dorsal and lumbar X-rays were performed to assess vertebral fractures. (who.int)
  • As a result of the COVID-19 pandemic , a large number of hospital systems were forced to reduce operating room capacity and reallocate resources, with unclear answers on the outcome of these policy decisions on the care of acutely injured patients. (consultantlive.com)
  • Chirodian N, Arch B, Parker MJ (2005) Sliding hip screw fixation of trochanteric hip fractures: outcome of 1024 procedures. (springer.com)
  • To evaluate the impact of the COVID-19 pandemic on the outcome of non-COVID patients in Israel. (ima.org.il)
  • The prevalence of vertebral, hip and non-vertebral fractures did not increase in type 2 DM. (who.int)
  • More data is needed on the causes for an increased fracture risk in T2DM patients as well as on the predictors of osteoporotic fractures among these patients. (ox.ac.uk)
  • PPIs and other psychotropic medications were not associated with increased fracture risk. (bmj.com)
  • The anatomic site of this type of hip fracture is the proximal or upper part of the femur or thigh bone. (medscape.com)
  • The other two types of hip fractures are fractures of the femoral neck , which are proximal or cephalad to trochanteric fractures, and subtrochanteric fractures , which are distal to or below the trochanters. (medscape.com)
  • Metastatic cancer deposits in the proximal femur may weaken the bone and cause a pathological hip fracture. (wikipedia.org)
  • RESULTS: Patients had higher BMD in the lumbar spine (L2-L4) than controls (0.979 g/cm2 vs 0.927 g/cm2, p=0.035), but we found no statistically significant differences in the proximal femur. (who.int)
  • The patients were separated into two groups as those applied with proximal femoral nailing and those applied with calcar replacement hemiarthroplasty. (journaltocs.ac.uk)
  • Although all three types of fractures are commonly referred to simply as hip fractures, the above distinctions between them are important because the anatomy, prognosis, and management are different for each type. (medscape.com)
  • Tension fractures have a poor prognosis and tend to be unstable. (medscape.com)
  • A total of 38 patients at a tertiary-care institution with chronic abdominal pain from chronic pancreatitis (17 with VAPS and 21 with AMPS) underwent bilateral subcostal transversus abdominis plane (STAP) blocks with depot methylprednisolone 80 mg. (asra.com)
  • 95% (20/21) of patients with AMPS who underwent bilateral STAP had clinically significant pain relief at 3 months, and 62% (13/21) of patients had durable relief. (asra.com)
  • Of the 17 patients with VAPS who underwent STAP blocks, 100% failed treatment (17/17). (asra.com)
  • For the evaluation of the positioning of the tibial component, the patients underwent computed tomography (CT) four weeks after the surgery, on average. (journaltocs.ac.uk)
  • Patients who underwent which decreases the bone quantity and quali- standard posterior-anterior and lateral chest ty causing fragility fractures. (who.int)
  • Such fractures most often occur as a result of a fall. (wikipedia.org)
  • Shortening, varus deformity, valgus deformity, and rotational malunion all occur often because the fracture may be unstable and collapse before it heals. (wikipedia.org)
  • Stress fractures may occur in the hip region with metabolic bone disease. (wikipedia.org)
  • Stress fractures occur most often in the femoral neck and are classified according to the location (ie, inferior or compression, superior or tension). (medscape.com)
  • Loss of position before healing can also occur if the fixation device fails because of improper insertion or if the fracture does not heal before the end of the mechanical life of the device. (medscape.com)
  • 9 ] also found that after adjustment for sex, age, and medications used, HF was more likely to occur in stroke patients than in controls matched for age and sex (hazard ratio 1.89). (biomedcentral.com)
  • however, hip fractures also occur and are concerning. (e-agmr.org)
  • Although NAs are generally safe and relatively free of major side effects, [ 10 ] nephrotoxicity and bone toxicity may occur in a small yet significant proportion of patients receiving older generations of nucleotide analogues, for example, adefovir and TDF. (medscape.com)
  • Typically, lymphedema-associated angiosarcomas occur in women who have undergone radical mastectomy for breast carcinoma and have had chronic lymphedema for many years (Stewart-Treves syndrome) or in the leg of patients as a consequence of radical inguinal lymphadenectomy for metastases from malignant melanoma (Kettles syndrome). (medscape.com)
  • Introduction: Dual mobility cups (DMC) are gaining in popularity, as a method to reduce the risk of dislocation after fracture-related hip arthroplasty. (lu.se)
  • Adam P, Philippe R, Ehlinger M, Roche O, Bonnomet F, Molé D, Fessy MH, French Society of Orthopaedic Surgery and Traumatology (SoFCOT) (2012) Dual mobility cups hip arthroplasty as a treatment for displaced fracture of the femoral neck in the elderly. (springer.com)
  • For displaced fractures, surgeons choose between internal fixation or arthroplasty, depending on patient characteristics and surgeon preference. (aaos.org)
  • For all other factures that they intend to fix without arthroplasty, they need to use a sliding hip screw. (aaos.org)
  • During follow-up a total of 5,552 incident hip fractures were recorded. (aprifel.com)
  • Cases included all patients with an incident hip fracture. (nih.gov)
  • Previously published studies of the relationships between prior wrist fracture and incident hip and vertebral fractures did not adjust for BMD. (healthpartners.com)
  • Incident hip fractures were confirmed with radiographic reports over a mean follow-up period of 10.1 years. (healthpartners.com)
  • The association between prior wrist fracture and incident hip fracture is largely explained by hip BMD. (healthpartners.com)
  • abstract = "Aim: To measure functional recovery and determine risk factors for failure to return to the prefracture level of mobility of hip fracture patients 1year postoperatively. (vu.nl)
  • A trochanteric hip fracture occurs between the greater trochanter, where the gluteus medius and the gluteus minimus (hip extensors and abductors) attach, and the lesser trochanter, where the iliopsoas (hip flexor) attaches. (medscape.com)
  • Ban I, Birkelund L, Palm H, Brix M, Troelsen A (2012) Circumferential wires as a supplement to intramedullary nailing in unstable trochanteric hip fractures: 4 reoperations in 60 patients followed for 1 year. (springer.com)
  • Azegami S, Gurusamy KS, Parker MJ (2011) Cemented versus uncemented hemiarthroplasty for hip fractures: a systematic review of randomised controlled trials. (springer.com)
  • Siclari F, Valli K, Arnulf I. Dreams and nightmares in healthy adults and in patients with sleep and neurological disorders. (jmir.org)
  • 5 One in three adults who lived independently before their hip fracture subsequently resided in a nursing home for at least a year after their injury. (cdc.gov)
  • It took place in 20 medical sites across the US and Canada, with adults aged ≥18 years presenting with an open fracture of an extremity requiring surgery or closed lower extremity or pelvis fracture requiring surgery. (consultantlive.com)
  • Although the relationship between acid-suppressive drugs and bone health is uncertain, some experts have speculated that PPI use may interfere with bone metabolism and decrease calcium absorption, thereby increasing the risk for fractures. (primeinc.org)
  • Healthy People 2020 Objective AOCBC-11.1: Reduce hip fractures among females aged ≥65 years. (cdc.gov)
  • Secondary analysis of prospective cohort data from the control group of the Delirium Prevention Trial. (nzno.org.nz)