• This is the most common type of cancer during childhood, and acute lymphoblastic leukemia (ALL) is most common in children. (wikipedia.org)
  • Association of MIR3117 and MIR612 Genes Polymorphisms with Childhood Acute Lymphoblastic Leukemia in the Mexican Population. (cdc.gov)
  • Relapse risk following truncation of PEG-asparaginase in childhood acute lymphoblastic leukemia. (cancercentrum.se)
  • Background: A childhood cancer diagnosis and treatment-induced somatic late effects can affect the long-term mental health of survivors. (lu.se)
  • We followed up our study population from 5 years after the childhood cancer diagnosis or corresponding calendar date for matched individuals (the index date) until Aug 11, 2017, and assessed information on hospital contacts for any and specific psychiatric disorders. (lu.se)
  • Results: Overall, 302 out of the 36 205 CCS developed symptomatic cardiac ischaemia during follow-up (median follow-up time after primary cancer diagnosis: 23.0 years). (lu.se)
  • The likelihood of reporting a cancer-related visit or a general physical examination decreased significantly as the survivor aged or the time from cancer diagnosis increased. (nih.gov)
  • Reproductive outcomes following treatment for a gynecological cancer diagnosis: a systematic review. (cancer.org.au)
  • A major focus of the program is also directed at early diagnosis and intervention for survivors with psychosocial and neuropsychological concerns. (texaschildrens.org)
  • WECARE enrolled patients with breast cancer who had survived at least 1 year after diagnosis. (ascopost.com)
  • Within the first 30 years after diagnosis, survivors of childhood cancers have approximately a 75% cumulative incidence of treatment-related chronic health problems. (ajmc.com)
  • 4 In fact, 30 years after diagnosis, the number of cardiac-related deaths among survivors exceeds the number caused by cancer recurrence. (ajmc.com)
  • 5 The prevalence of cardiovascular events, even 5 years after diagnosis, is higher in survivors than in healthy controls (see Figure 1 ). (ajmc.com)
  • With the consideration of age at childhood cancer diagnosis and attained age, we observe a significant decline in survivors' invasive breast cancer incidence rate in more recent treatment eras," they continued. (medpagetoday.com)
  • The prevalence of childhood cancer survivors is estimated to have increased, and the majority of those who have survived five or more years beyond diagnosis may have at least one chronic health condition, a new report suggests. (sciencedaily.com)
  • The goal of the study was to update prevalence estimates of childhood cancer survivors in the United States and estimate the burden of morbidity among those who survived five years or longer since diagnosis, according ot Phillips. (sciencedaily.com)
  • Of these survivors, about 84 percent had survived five or more years post-diagnosis. (sciencedaily.com)
  • Parental communication and children's behavior following diagnosis of childhood leukemia. (scriptiebank.be)
  • Pediatric oncology is the branch of medicine concerned with the diagnosis and treatment of cancer in children. (wikipedia.org)
  • Borch KB, Braaten T, Lund E, Weiderpass E . Physical activity before and after breast cancer diagnosis and survival - the Norwegian women and cancer cohort study. (kreftregisteret.no)
  • The National Cancer Institute ([NCI], 2022) reported that 296,381 individuals in the United States had a cervical cancer diagnosis in 2020. (ons.org)
  • Characteristics associated with higher hospitalisation rates included female gender, diagnosis with malignant bone tumours, cancer diagnosis age between 5-9 years, multiple childhood cancer diagnoses, higher comorbidity, high socio-economic deprivation, and geographic remoteness. (authorea.com)
  • A higher risk of hospitalisation for physical disease was observed in CCS compared with children not diagnosed with cancer, with the risk continuing to increase up to 30 years post-diagnosis. (authorea.com)
  • median follow-up from diagnosis was 29 years (range 5-48) in the Childhood Cancer Survivor Study. (duke.edu)
  • Survivors 40 years or more from diagnosis experienced 131 excess health-related deaths per 10 000 person-years (95% CI 111-163), including those due to the top three causes of health-related death in the general population: cancer (absolute excess risk per 10 000 person-years 54, 95% CI 41-68), heart disease (27, 18-38), and cerebrovascular disease (10, 5-17). (duke.edu)
  • INTERPRETATION: Survivors of childhood cancer are at excess risk of late mortality even 40 years from diagnosis, due to many of the leading causes of death in the US population. (duke.edu)
  • The patients had a median age of 6.1 years at cancer diagnosis and a median age of 29.4 years at last follow-up. (hematologyadvisor.com)
  • The primary outcome was any self-reported late, major surgical intervention that required anesthesia and occurred 5 years or more after the survivors' initial cancer diagnosis. (hematologyadvisor.com)
  • In Sweden, approximately 350 children are diagnosed with cancer yearly, whereas 55 000-60 000 adults receive a cancer diagnosis. (lu.se)
  • People who continue to smoke after a cancer diagnosis have an increased risk for recurrences or development of new malignancies. (cdc.gov)
  • We recommend all cancer survivors be made aware of the health risks associated with smoking after a cancer diagnosis, and smoking cessation services be offered to those who currently smoke. (cdc.gov)
  • Continued smoking after a cancer diagnosis places survivors at increased risk for recurrences or development of new malignancies [ 10 - 12 ]. (cdc.gov)
  • Falk Delgado A, Nilsson M, Latini L, MÃ¥rtensson J, Zetterling M, Ghaderi Berntsson S, Alafuzoff I, Lätt J, Larsson E-M. Preoperative semi-quantitative MR tractography compared with visual tract evaluation and neuropathological diagnosis in patients with suspected low-grade glioma: A prospective cohort study. (lu.se)
  • More than 70% of all cancer deaths occur in low- and middle-income countries, where the resources available for prevention, diagnosis and treatment of cancer are limited or nonexistent. (who.int)
  • To improve mental health and the overall quality of life after childhood cancer, survivorship care should include a focus on early signs of mental health problems, especially among high-risk groups of survivors. (lu.se)
  • Survivors who are uninsured, female, and living with a chronic health condition were all at greater risk of not getting needed medical care because of cost, according to data presented here at the Cancer Survivorship Symposium Advancing Care and Research. (medscape.com)
  • In an interview, Phillips said, "Our study findings highlight that a singular focus on curing cancer yields an incomplete picture of childhood cancer survivorship. (sciencedaily.com)
  • Cancer survivorship experiences in Utah: an evaluation assessing indicators of survivors' quality of life, health behaviors, and access to health services. (utah.edu)
  • However, such an evaluation is not warranted, especially because such a study would not help the National Cancer Institute address the critical strategic issues it faces with respect to the future of its pediatric cancer survivorship research portfolio. (ida.org)
  • Prior to the PanCare meeting a half-day educational meeting was organised for young researchers to provide background information on childhood cancer (survivorship) and scientific work and methods. (pancare.eu)
  • Meeting started with many interesting presentations of our Italian hosts about follow up care for childhood cancer survivors, including introduction of survivorship passports, and some research on late sequelae. (pancare.eu)
  • Many very interesting and exciting abstracts were presented in next sessions covering very different topics, among others implementation of survivorship passports, fertility preservation, problems of transition of long-term survivors of childhood cancer into adult care. (pancare.eu)
  • St. Jude follows over 6,000 childhood cancer survivors enrolled in the St. Jude Lifetime Cohort Study (SJLIFE). (medicalxpress.com)
  • 40 years) among 799 female survivors of childhood cancer participating in the St. Jude Lifetime Cohort Study (SJLIFE). (chop.edu)
  • Methods: In this register-based cohort study (part of the Socioeconomic Consequences in Adult Life after Childhood Cancer [SALiCCS] research programme), we included 5-year survivors of childhood cancer diagnosed before 20 years of age between Jan 1, 1974 and Dec 31, 2011, in Denmark, Finland, and Sweden. (lu.se)
  • Objective: In this report, we determine the cumulative incidence of symptomatic cardiac ischaemia and its risk factors among European 5-year childhood cancer survivors (CCS) participating in the PanCareSurFup study. (lu.se)
  • We analyzed data from 9,434 adult childhood cancer survivors enrolled in a retrospective cohort study who completed a baseline questionnaire. (nih.gov)
  • Design Observational cohort study. (bmj.com)
  • A prospective register study, with 15 years follow-up, in a cohort of nurses' aides found that risk factors for disability pension were mainly health related (eg, low back pain, sick leave spells), whereas economic factors (eg, income of spouse) influence the decision to retire early. (bmj.com)
  • Childhood cancer survivors are at a significantly higher risk of a severe mental health event requiring an emergency department (ED) visit or hospitalization, according to a new study by researchers at the Institute for Clinical Evaluative Sciences (ICES) and The Hospital for Sick Children (SickKids). (ices.on.ca)
  • In the study published today in Cancer , researchers examined data representing 4,117 childhood cancer survivors and 20,269 controls, and observed that rates of mental health care visits to family physicians and psychiatrists as well as the risk for a severe mental health event were significantly increased in survivors. (ices.on.ca)
  • While previous research has shown that childhood cancer survivors have an elevated risk of physical health issues later in life, our study shows that these same survivors are also at risk for mental health challenges," says Dr. Sumit Gupta , co-author of the study, adjunct scientist at ICES and staff oncologist and clinician investigator at SickKids. (ices.on.ca)
  • Our study shows that female survivors of adolescent cancers are at the highest risk of seeing a family doctor or psychiatrist for a mental health issue," says Dr. Paul Nathan , co-author on the study, adjunct scientist at ICES, staff oncologist, clinician investigator and the director of the Aftercare program in the Division of Haematology/Oncology at SickKids. (ices.on.ca)
  • 1 A second study showed an increase in breast cancer among women who received low levels of radiation to the chest as children. (ascopost.com)
  • Historical data suggest that adolescent and young adult patients with high-risk ALL have inferior outcomes, but a direct comparison by age group, in a large enough trial, has not been available until now, said Eric Larsen, MD , of the Maine Children's Cancer Program and Study Chair of the COG. (ascopost.com)
  • The risk of developing breast cancer after receiving radiotherapy to the chest as a child are as high as those for BRCA1 and BRCA2 mutation carriers, according to review of 1,268 cancer survivors participating in the Childhood Cancer Survivor Study (CCSS) and 4,570 female first-degree relatives of participants in the Women's Environmental Cancer and Radiation Epidemiology (WECARE) Study. (ascopost.com)
  • CCSS is a large North American cohort study of long-term childhood cancer survivors. (ascopost.com)
  • The study, published today in Genome Medicine , is the first to identify genetic risk factors for accelerated aging in pediatric cancer survivors. (medicalxpress.com)
  • Ranitidine study finds no elevated risk of cancer. (medicalxpress.com)
  • Rates of breast cancer among female childhood cancer survivors have declined significantly since 1970, coinciding with changes in treatment for childhood cancers, a large retrospective cohort study showed. (medpagetoday.com)
  • The study corroborated previous research showing decreased incidence of secondary breast cancer (SBC) over time and an increased risk associated with prior chest RT and anthracycline exposure, noted the authors of an accompanying editorial . (medpagetoday.com)
  • To address the limitation, Henderson and colleagues analyzed data from the Childhood Cancer Survivor Study , a cohort of childhood cancer survivors treated at 31 North American centers. (medpagetoday.com)
  • Objectives: The purpose of this study is to investigate the effect of Web-based versus paper-based questionnaires on participation rates in a questionnaire survey on late effects among childhood cancer survivors (CCSs). (websm.org)
  • This is a representative depiction of the situation confronting children followed by the Childhood Cancer Survivor Study and, more than likely, most Americans, who are underinsured," he said. (medscape.com)
  • Our study is unique because we are looking only at survivors of childhood cancers," he told Medscape Medical News . (medscape.com)
  • In their study, Dr Fair and his colleagues assessed long-term survivors who participated in the Childhood Cancer Survivor Study, which was started in 1994 to understand late effects, increase survival, and minimize harmful health effects. (medscape.com)
  • The researchers used cancer incidence and survival data recorded between 1975 and 2011 from nine U.S. Surveillance, Epidemiology, and End Results (SEER) registries, and data from the Childhood Cancer Survivor Study (CCSS) cohort that had information on a range of potential adverse and late effects of cancer treatment from more than 14,000 long-term survivors of childhood cancers at 26 cancer centers across the United States and Canada. (sciencedaily.com)
  • Mar. 5, 2021 A new study finds a possible link between slow walking pace and an increased risk of death among cancer survivors. (sciencedaily.com)
  • And in 2018, researchers from St. Jude and elsewhere described common and rare genetic contributors to breast cancer risk in Lifetime Cohort study participants. (genomeweb.com)
  • That Clinical Cancer Research study highlighted pathogenic or likely pathogenic variants in known breast cancer-related genes, along with a proposed polygenic risk score made up of common risk variants. (genomeweb.com)
  • Since 2007, she has collaborated with and led several studies with the national Childhood Cancer Survivor Study (CCSS). (utah.edu)
  • Age-related differences in employment, insurance, and financial hardship among colorectal cancer patients: a report from the ColoCare Study. (utah.edu)
  • The National Cancer Institute-supported Childhood Cancer Survivor Study (CCSS) is a cohort of approximately 20,000 survivors and approximately 4,000 siblings of survivors of pediatric cancers diagnosed between 1970 and 1986. (ida.org)
  • A recently initiated expansion of the study aims to enroll an equally large cohort of survivors diagnosed between 1987 and 1999. (ida.org)
  • Investigators can use CCSS funds to conduct analyses of the data collected through the cohort study, as well as to use outside funds for research making use of the cohort. (ida.org)
  • The focus of the CVSS study is cardiovascular disease research in individuals after childhood cancer. (unimedizin-mainz.de)
  • This prospective cohort study is designed to gain a better understanding of the incidence, causes and progression of cardiovascular disease after childhood cancer. (unimedizin-mainz.de)
  • It benefits from the close interdisciplinary cooperation between the Pediatric Hematology/Oncology of the Center for Pediatric and Adolescent Medicine, the German Childhood Cancer Registry (DKKR) at the Institute of Medical Biometry, Epidemiology and Informatics (IMBEI) as well as the Gutenberg Health Study (GHS) at the 2nd Medical Clinic and Polyclinic (Cardiology and Angiology Clinic) at the University Medical Center of the Johannes Gutenberg University Mainz. (unimedizin-mainz.de)
  • This study examines 1,000 individuals who were treated for childhood cancer at Mainz University Hospital or surrounding hospitals between 1980 and 1990. (unimedizin-mainz.de)
  • 09.50-10.10 Carboxyhaemoglobin level, smoking habit, and mortality in 25 years in the Renfrew/Paisley prospective cohort study . (bmj.com)
  • The UK Children's Cancer Study Group's (UK CCSG) best practice statement 9 is a potentially valuable companion guideline for tertiary care practitioners requiring details of therapeutic regimens and their toxicity profiles to individualise care for those most affected. (bmj.com)
  • Results of the prospective cohort study ikidS-OEVA. (bvsalud.org)
  • The adult life after childhood cancer in scandinavia (ALiCCS) study: Design and characteristics. (kreftregisteret.no)
  • Social inequalities and smoking-associated breast cancer - results from a prospective cohort study. (kreftregisteret.no)
  • PMID: 34278568.Brief Summary: This population-based study retrospectively compared hospital admissions for skeletal issues in a group of 26,334 cancer survivors (CCS) diagnosed before 20 years of age and 127,531 matched controls. (espeyearbook.org)
  • Researchers calculated CIRS-G scores in cancer survivors and their siblings from the Childhood Cancer Survivor Study as well as in participants from the National Health and Nutrition Examination Survey (NHANES), who represented the general population. (cancertherapyadvisor.com)
  • The study included 14,355 cancer survivors and 4022 siblings who completed a survey at baseline (1992-2005), 6138 cancer survivors and 1801 siblings who completed a follow-up survey (2014-2016), and 31,126 NHANES participants (1999-2004). (cancertherapyadvisor.com)
  • Are dietary reports in a case-control study on thyroid cancer biased by risk perception of Chernobyl fallout? (inserm.fr)
  • Adult survivors of childhood cancers may develop frailty at higher rates than expected, leading researchers to suggest mitigating known risk factors for frailty in this population, according to a study. (medjournal360.com)
  • In this study, frailty was assessed when the cancer survivor entered the study and again 5 years later. (medjournal360.com)
  • Among all survivors, risk factors for frailty included chest radiation ≥20 Gy, cardiac/neurological conditions, lack of strength training, sedentary lifestyle, and frailty at study entry. (medjournal360.com)
  • Longitudinal strain is only mildly reduced in pediatric childhood cancer survivors (CCSs) and associated with age at the time of the study and higher body surface area. (thechipnetwork.org)
  • This large multicenter study included 546 pediatric childhood cancer survivors (CCSs)and assessed if echocardiographic strain parameters are of utility for the identification of patients at risk for cardiac dysfunction. (thechipnetwork.org)
  • Scholars@Duke publication: Specific causes of excess late mortality and association with modifiable risk factors among survivors of childhood cancer: a report from the Childhood Cancer Survivor Study cohort. (duke.edu)
  • Replication was performed using self-reported PM in 1624 survivors participating in the Childhood Cancer Survivor Study (CCSS). (chop.edu)
  • Haemodynamic gain index is associated with risk of sudden cardiac death and improves risk prediction: a cohort study. (cpxinternational.com)
  • We aimed to assess the association of HGI with SCD risk in a long-term prospective cohort study. (cpxinternational.com)
  • This finding suggests that further study is warranted with a larger sample set that is more uniformly distributed in age and sex to assess the impact on clinical or research studies of the risk of subsequent hematological malignancies for survivors of childhood radiation therapy. (appliedradiationoncology.com)
  • An analysis of the Childhood Cancer Survivor Study showed a higher risk of late, major surgical interventions among childhood cancer survivors than among their siblings. (hematologyadvisor.com)
  • T]his study demonstrates a newly understood chronic late effect of pediatric cancer therapy comprising a significant burden of late, major surgical interventions," the researchers concluded. (hematologyadvisor.com)
  • Germline Genetic and Treatment-Related Risk Factors for Diabetes Mellitus in Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study and St Jude Lifetime Cohorts. (cdc.gov)
  • Health-status of adult survivors of childhood cancer: a large-scale population-based study from the British Childhood Cancer Survivor Study. (ox.ac.uk)
  • The purpose of this study was to investigate the effect of childhood cancer and its treatment on self-reported health-status in 10,189 adult survivors of childhood cancer in Britain. (ox.ac.uk)
  • Although self-reported physical health is at least as good as in the general population among young survivors, this study suggests that perceived physical health declines more rapidly over time than in the general population. (ox.ac.uk)
  • There were presentations on analysis of risk factors for heart failure, subsequent colorectal and oral cancer in a cohort of PCSF study, on toxicity of childhood cancer treatment on endocrine system, liver, spleen and reports on psychosocial outcome after childhood cancer treatment. (pancare.eu)
  • Hospitalizations in long-term survivors of childhood AML treated with allogeneic HCT-An Adult Life after Childhood Cancer in Scandinavia (ALiCCS) study. (cancercentrum.se)
  • Study protocol for the Fex-Can Childhood project: An observational study and a randomized controlled trial focusing on sexual dysfunction and fertility-related distress in young adult survivors of childhood cancer. (cancercentrum.se)
  • Statin Use and Skin Cancer Risk: A Prospective Cohort Study. (who.int)
  • Risk Stratification for Early-Onset Colorectal Cancer Using a Combination of Genetic and Environmental Risk Scores: An International Multi-Center Study. (who.int)
  • an observational cohort study. (cdc.gov)
  • In a study comparing 4 member countries of the Middle East Cancer Consortium (Cyprus, Egypt, Israel and Jordan) with the Surveillance, Epidemiology and End Results (SEER) survey in the United States of America (USA), the overall incidence of cancer was substantially higher in the USA and in Israeli Jews than in other Middle East populations [3]. (who.int)
  • Experiences of ICU survivors in a low middle income country- a multicenter study. (medscape.com)
  • Visual quality assessment of the liver graft by the transplanting surgeon predicts postreperfusion syndrome after liver transplantation: a retrospective cohort study. (medscape.com)
  • Pre-anesthetic assessment with three core questions for the detection of obstructive sleep apnea in childhood: An observational study. (medscape.com)
  • They first obtained estimates of the probability of each measure of morbidity from CCSS and then multiplied these estimates by the relevant number of survivors in the United States estimated from the SEER data. (sciencedaily.com)
  • this finding was replicated in an independent second cohort of CCSS in spite of its use of self-reported PM (OR = 3.97, 95% CI = 1.67 to 9.41, P = .002). (chop.edu)
  • This is one of a series of studies my lab has undertaken to investigate aging biomarkers in childhood cancer survivors ," said corresponding author Zhaoming Wang, Ph.D., of the Departments of Epidemiology and Cancer Control and Computational Biology. (medicalxpress.com)
  • Cancer Epidemiology Biomarkers and Prevention. (tau.ac.il)
  • interests include the epidemiology and prevention of Pediatric Cancer viral infectious diseases. (cdc.gov)
  • New Horizons: Epidemiology of Obesity, Diabetes Mellitus, and Cancer Prognosis. (medscape.com)
  • Metastatic spread pattern after curative colorectal cancer surgery. (kreftregisteret.no)
  • Longitudinal associations of plasma metabolites with persistent fatigue among colorectal cancer survivors up to 2 years after treatment. (who.int)
  • Genetic Regulation of DNA Methylation Yields Novel Discoveries in GWAS of Colorectal Cancer. (who.int)
  • Sequencing data from the St. Jude Lifetime Cohort is part of the St. Jude Cloud, a dataset encompassing thousands of genome, exome, and RNA sequences that is open to other members of the research community that officially launched in 2018 . (genomeweb.com)
  • Long-Term Follow-Up in Childhood Cancer Survivors - Position paper 2018 of the working group "long-term follow-up" of the Society of Pediatric Oncology and Hematology (GPOH) on long-term surveillance, long-term follow-up and late effect evaluation in pediatric oncology patients]. (bvsalud.org)
  • The U.S. Preventive Services Task Force ([USPSTF], 2018) recommends cervical cancer screening for individuals with a cervix aged 21-29 years every three years using cervical cytology (i.e. (ons.org)
  • Cost of Cancer in Adolescents and Young Adults in the United States: Results of the 2021 Report by Deloitte Access Economics, Commissioned by Teen Cancer America. (utah.edu)
  • Risk Factors and Trends for HPV-Associated Subsequent Malignant Neoplasms among Adolescent and Young Adult Cancer Survivors. (utah.edu)
  • We wanted to determine the type of outpatient medical care reported by young adult survivors of childhood cancer and to examine factors associated with limited medical care. (nih.gov)
  • Previous studies of adult and adolescent/young adult survivors looking at cost as being a barrier to care have shown that it does cause decreased utilization, explained lead researcher Douglas Fair, MD, a pediatric oncologist from the University of Utah in Salt Lake City. (medscape.com)
  • Cancer Epidemiol Biomarkers Prev , 32 (5), 625-633. (utah.edu)
  • Cancer Epidemiol Biomarkers Prev. (kreftregisteret.no)
  • Blood cell DNA methylation biomarkers in preclinical malignant pleural mesothelioma: The EPIC prospective cohort. (who.int)
  • Childhood cancer pediatric oncology - SIOP The Netherlands Europe. (scriptiebank.be)
  • 8 The Guideline Development Group (GDG) included representatives from paediatric haematology, oncology, endocrinology, reproductive medicine, cardiology, general paediatrics and general practice, as well as a survivor. (bmj.com)
  • I also work towards a Swedish and Nordic common neuropsychological protocol for survivors of childhood cancer and a common database which would be of benefit to researchers within pediatric oncology, whether evaluating cancer treatment protocols or chronic conditions among survivors. (lu.se)
  • Pediatric oncologists should actively improve oncology practices to better integrate individualized school plans and educate peers and teachers to improve health literacy to aid them in understanding the needs of children with cancer. (e-cep.org)
  • Since Sidney Farber proposed the first treatment for childhood cancer in 1948, the field of pediatric oncology has been constantly evolving. (medscape.com)
  • Pediatric oncology focuses on diagnosing and treating cancer in children and adolescents, presenting unique challenges due to the rarity and diverse nature of childhood cancers. (lu.se)
  • We aimed to explore whether childhood cancer survivors are at higher risk of psychiatric disorders later in life than their siblings and the general population. (lu.se)
  • Survivors were compared with their siblings and randomly selected individuals from the general population who were matched to the survivors by year of birth, sex, and geographical region. (lu.se)
  • For siblings, the index date was defined as 5 years from the date on which they were of the same age as their sibling survivor when diagnosed with cancer. (lu.se)
  • The cumulative incidence proportion of having had a psychiatric hospital contact by 30 years of age between Jan 1, 1979, and Aug 11, 2017, was 15·9% (95% CI 15·3-16·5) for childhood cancer survivors, 14·0% (13·5-14·5) for siblings, and 12·7% (12·4-12·9) for matched individuals. (lu.se)
  • Despite a small absolute difference, survivors were at higher relative risk of any psychiatric hospital contact than their siblings (1·39, 1·31-1·48) and matched individuals (hazard ratio 1·34, 95% CI 1·28-1·39). (lu.se)
  • Survivors had a higher burden of recurrent psychiatric hospital contacts and had more hospital contacts for different psychiatric disorders than their siblings and the matched individuals. (lu.se)
  • Interpretation: Childhood cancer survivors are at higher long-term risk of psychiatric disorders than their siblings and matched individuals from the general population. (lu.se)
  • These retrospective cohort studies involve large numbers of childhood cancer survivors and their siblings. (cancer.org.au)
  • Women treated for cancer in childhood have an increased risk of infertility [8][9] and an increased time to pregnancy compared with their siblings. (cancer.org.au)
  • The role of emotional social support in the psychological adjustment of siblings of children of cancer. (scriptiebank.be)
  • At follow-up, the mean CIRS-G total score was 7.76 among cancer survivors and 4.79 among siblings. (cancertherapyadvisor.com)
  • The median age at baseline was 24 years among cancer survivors and 26 years among siblings. (cancertherapyadvisor.com)
  • The cancer survivors had a greater risk than their siblings for grade 1-4 conditions in all organ systems (relative risk [RR], 1.13-2.26) except respiratory and genitourinary. (cancertherapyadvisor.com)
  • When the researchers adjusted for age at baseline, sex, and race/ethnicity, all CIRS-G severity measures predicted death in the cancer survivors, siblings, and the NHANES cohort. (cancertherapyadvisor.com)
  • C]hildhood cancer survivors have increased burden of disease across organ systems relative to siblings and the general population. (cancertherapyadvisor.com)
  • The cancer survivors were compared to 5045 of their nearest-age siblings. (hematologyadvisor.com)
  • The median follow-up was 21.8 years for the cancer survivors and 27.0 years for the siblings. (hematologyadvisor.com)
  • The number of late, major surgical interventions was 28,202 among the cancer survivors and 4110 among the siblings. (hematologyadvisor.com)
  • As a health services researcher, her program primarily concerns evaluating patient outcomes related to healthcare access and cancer late effects, and developing interventions for childhood, adolescent and young adult cancer survivors, with a focus on addressing the social and financial consequences of cancer. (utah.edu)
  • COVID-19-Related Employment Disruptions and Increased Financial Burden Among Survivors of Adolescent and Young Adult Cancer. (utah.edu)
  • Reproductive outcomes following a stem cell transplant for a haematological malignancy in female cancer survivors: a systematic review and meta-analysis. (cancer.org.au)
  • As the cancer survivor population has grown, the significant risk for treatment-related health outcomes of therapies has become clear," the authors wrote. (medpagetoday.com)
  • Dr. Kirchhoff leads a range of studies from interventions at Huntsman Cancer Institute and Primary Children's Hospital to statewide analyses of survivor outcomes using the Utah Population Database. (utah.edu)
  • Her research interests also include using large, population-based surveys to examine socioeconomic outcomes of cancer survivors. (utah.edu)
  • As a post-doctoral fellow at St. Jude, I examined neurocognitive outcomes in survivors of Wilms tumor and soft tissue sarcoma. (lu.se)
  • These are the first comprehensive reports of adverse neurocognitive outcomes in these groups of survivors. (lu.se)
  • Through this work I identified two potentially modifiable targets for intervention to improve cognitive outcomes in survivors. (lu.se)
  • to encourage cooperation between different researchers, or between clinicians and researches within our network with the ultimate goal of improving the outcomes and quality of life of child cancer patients. (lu.se)
  • Methods: Eight data providers (France, Hungary, Italy (two cohorts), the Netherlands, Slovenia, Switzerland and the UK) participating in PanCareSurFup ascertained and validated symptomatic cardiac events among their 36 205 eligible CCS. (lu.se)
  • To optimize risk-based care, it is critical that cancer centers and primary care physicians develop methods to communicate effectively and longitudinally. (nih.gov)
  • [1] With five-year disease-free survival rates now surpassing 80% for young people, [2] health care providers need to provide information about the risks of infertility to patients with cancer. (cancer.org.au)
  • Between 2004 and 2010, the survival rate in the United States in children up to 14 years of age with all types of cancer was 83%- significantly higher than the 58% reported in the mid-1970s. (ajmc.com)
  • Although 5-year survival of childhood cancers has improved over time, survivors continue to have an excess risk of premature mortality, and treatment-related (secondary) malignancies make a substantial contribution to the excess mortality risk. (medpagetoday.com)
  • 09.00-09.20 Recent trends in breast cancer survival in North Cheshire . (bmj.com)
  • Five-year childhood cancer survival rates have increased to 80-90% for some tumours due to intensified treatments and better supportive care imposed on an incidence stable over four decades. (bmj.com)
  • BACKGROUND: 5-year survival after childhood cancer does not fully describe life-years lost due to childhood cancer because there are a large number of deaths occurring beyond 5-years (late mortality) related to cancer and cancer treatment. (duke.edu)
  • [ 2 ] As a consequence of these incredible survival rates, the number of childhood cancer survivors continues to grow, with current estimates surpassing 300,000. (medscape.com)
  • In the United States, where 1 in 680 people between 20 and 50 years old are survivors of childhood cancer, the impact of long-term health consequences is a cause for concern, and even more so because this population is increasing. (ajmc.com)
  • More than 80% of children diagnosed with cancer will survive at least 5 years and become long-term survivors. (medscape.com)
  • 10.15-10.35 Risk of relapse and associated prognostic factors in long term survivors of childhood cancer in Yorkshire, UK . (bmj.com)
  • In March 2013, the Scottish Intercollegiate Guidelines Network (SIGN) published updated guidance on long-term follow-up of childhood cancer survivors to aid the 'identification, assessment and management of late effects' aimed at primary, secondary and tertiary healthcare practitioners. (bmj.com)
  • The 41,000 long-term survivor cohort of the German Childhood Cancer Registry]. (bvsalud.org)
  • Childhood cancer patients] sometimes have long-term chronic side effects of the treatments that enabled them to survive to adulthood. (freethink.com)
  • A somewhat unanticipated consequence of us getting better at treating childhood cancers is that these patients sometimes, unfortunately, have long-term chronic side effects of the treatments that enabled them to survive to adulthood," Michael Hsieh, a urologist at Children's National Health System, told Freethink in 2019. (freethink.com)
  • In the Australian context, the long-term effects of childhood cancer on survivors and the health system are unclear. (authorea.com)
  • We were most touched by the presentation of a young colleague from Armenia Irina Melnichenko who presented their efforts to improve the treatment of children with cancer in their country and to establish long-term follow-up for childhood cancer survivors within twinning programme with Lars Hjorth from Sweden. (pancare.eu)
  • Conclusions: In this very large European childhood cancer cohort, we found that by age 60 years, 1 in 18 CCS will develop a severe, life-threatening or fatal cardiac ischaemia, especially in lymphoma survivors and CCS treated with radiotherapy and chemotherapy increases the risk significantly. (lu.se)
  • Surprisingly, women treated with radiotherapy to the chest for Hodgkin lymphomas have a risk of breast cancer that is remarkably similar to BRCA1 mutation carriers," said Chaya S. Moskowitz, PhD , a biostatistician at Memorial Sloan-Kettering Cancer Center, New York. (ascopost.com)
  • For women treated with 20 Gy or more of chest radiotherapy, the COG recommends breast cancer surveillance with annual mammograms and breast MRI starting at age 25, or 8 years after the radiation, whichever is last. (ascopost.com)
  • The declining breast cancer rate had a temporal association with declining use of chest radiotherapy (RT), from 34% of cases in the 1970s to 17% in the 1990s, as well as decreased use of pelvic irradiation in the treatment of childhood cancers. (medpagetoday.com)
  • NEW YORK - Secondary cancer risk appears to jump in pediatric cancer patients carrying risky germline variants in DNA repair genes who are exposed to DNA-damaging treatments such as chemotherapy or radiotherapy as part of their original treatment, new research suggests. (genomeweb.com)
  • By bringing in available medial record information on the patients' past chemotherapy doses and radiotherapy exposures, they found ties between secondary breast cancer risk in women with pathogenic germline mutations in homologous recombination genes, particularly after some chest radiotherapy or anthracycline chemotherapy treatments. (genomeweb.com)
  • The team's analysis also pointed to a rise in sarcoma risk after certain doses of alkylating chemotherapy in the past pediatric cancer patients with germline homologous recombination gene variants, while the cancer survivors with germline changes in genes from a nucleotide excision repair pathway appeared more prone to secondary thyroid cancer or non-melanoma skin cancer after earlier radiotherapy treatments. (genomeweb.com)
  • Second cancers in patients with locally advanced prostate cancer randomized to lifelong endocrine treatment with or without radical radiotherapy. (kreftregisteret.no)
  • Chemotherapy , radiotherapy , and other cancer treatments can cause infertility , so some patients will choose to freeze their sperm prior to beginning treatment. (freethink.com)
  • Collectively, our findings provide compelling evidence of increased [subsequent neoplasm] risk among childhood cancer survivors with [DNA repair gene] mutations and prior genotoxic treatment exposures," the authors wrote. (genomeweb.com)
  • This revision updates information on fertility preservation, cardiac late effects and patient information provision, and provides new sections on subsequent primary cancers (SPCs), bone health and metabolic syndrome. (bmj.com)
  • Healthy lifestyle behaviors (smoking cessation, physical activity, maintaining healthy weight, and consuming a healthy diet) may help improve quality of life among cancer survivors and prevent recurrent and subsequent cancers [ 6 ]. (cdc.gov)
  • The ultimate purpose of ongoing research is to develop successful interventions for survivors with late complications, as well as to design future cancer therapies that are not accompanied by the risk of late adverse effects. (texaschildrens.org)
  • Childhood cancer survivors had a significantly increased risk of late surgical interventions in many organ systems. (hematologyadvisor.com)
  • Survivors of Hodgkin lymphoma , Ewing sarcoma, and osteosarcoma had the highest burden of surgical interventions. (hematologyadvisor.com)
  • The highest burdens of late, major surgical interventions were seen in survivors of Hodgkin lymphoma (35-year MCC, 333.3 per 100 survivors), Ewing sarcoma (322.9 per 100), and osteosarcoma (269.6 per 100). (hematologyadvisor.com)
  • Targeted smoking prevention and cessation interventions are needed for cancer survivors, especially those diagnosed with a tobacco-related cancer. (cdc.gov)
  • U.S. Cancer Statistics Working Group, 2023). (ons.org)
  • Qian Dong et al, Genome-wide association studies identify novel genetic loci for epigenetic age acceleration among survivors of childhood cancer, Genome Medicine (2022). (medicalxpress.com)
  • Early screening reduces overall cancer risks through early detection (American Cancer Society, 2022). (ons.org)
  • These statistics additionally highlight that Hispanic women (10 per 100,000) and non-Hispanic American Indian and Alaska Native women (10.1 per 100,000) had the highest rates of cervical cancer and that Black, non-Hispanic women (3.4 deaths per 100,000) had the highest mortality (NCI, 2022). (ons.org)
  • International journal of cancer 2022 12 152 (7): 1388-1398. (cdc.gov)
  • However, while we wait for these long follow-up data to mature, many more patients with childhood cancer will be treated with RT and chemotherapy," they added. (medpagetoday.com)
  • These difficulties may be related to brain injury stemming from the cancer itself, such as a brain tumor or central nervous system metastasis or from side effects of cancer treatments such as chemotherapy and radiation therapy. (wikipedia.org)
  • 1 Furthermore, between 1970 and 2011, the death rates from cancers diagnosed in children up to 14 years old, and in adolescents 15 to 19 years old, declined by 67% (from 6.3 to 2.1 per 100,000 people) and 58% (from 7.2 to 3.0 per 100,000 people), respectively. (ajmc.com)
  • The analysis included 11,550 female participants, treated for childhood cancer from 1970 to 1999. (medpagetoday.com)
  • The 698 survey respondents (response rate, 64%) had been diagnosed with cancer from 1970 to 1986 and were younger than 21 years of age at the time of their cancer diagnoses. (medscape.com)
  • 7 While several cardiovascular toxicity studies have been conducted in adult cancer patients, far fewer have been conducted in pediatric cancer patients. (ajmc.com)
  • About 70 percent of the survivors of childhood cancers were estimated to have a mild or moderate chronic condition, and about 32 percent were estimated to have a severe, disabling, or life-threatening chronic condition. (sciencedaily.com)
  • More than 11 percent of the survivors carried pathogenic variants in one or more of the DNA repair genes profiled - alterations that together affected almost 100 different DNA repair genes, the researchers reported. (genomeweb.com)
  • We previously evaluated non- genetic risk factors including cancer treatments, health behaviors, and chronic health conditions that contribute to age acceleration. (medicalxpress.com)
  • But we found associations, and the more prominent ones related to cost were a lack of medical insurance, being female, and having a chronic medical condition, which 85% of the people in our cohort had. (medscape.com)
  • Psychosocial adjustment among pediatric cancer patients and their parents. (scriptiebank.be)
  • The CHK2 kinase is recurrently mutated and functionally impaired in the germline of pediatric cancer patients. (cdc.gov)
  • Approximately 11% of female childhood cancer survivors developed premature ovarian insufficiency (based on hormone criteria)in one cohort although the frequency varies 3 . (menopause.org.au)
  • These SNPs in combination with other non-genetic risk factors may allow physicians in the future to identify the survivors at higher risk of accelerated aging before they develop premature aging symptoms. (medicalxpress.com)
  • Like other cancer survivors, they face an elevated lifetime risk for morbidity and premature death stemming from their disease and/or treatment. (medscape.com)
  • Researchers have used a geriatric rating scale to show that childhood cancer survivors experience accelerated aging and have a higher risk of premature death than the general population. (cancertherapyadvisor.com)
  • A High-risk Haplotype for Premature Menopause in Childhood Cancer Survivors Exposed to Gonadotoxic Therapy. (chop.edu)
  • Childhood cancer survivors are at increased risk of therapy-related premature menopause (PM), with a cumulative incidence of 8.0%, but the contribution of genetic factors is unknown. (chop.edu)
  • A meta-analysis of the neurocognitive sequelae of treatment for childhood acute lymphocytic leukemia. (scriptiebank.be)
  • In separate studies, I examined the contribution of insomnia and pain to neurocognitive functioning in survivors of childhood cancer. (lu.se)
  • Without significant difficulties, because most neurocognitive impairments in cancer survivors manifest over time. (oncologytube.com)
  • Primary bone cancer in Leonbergers may be associated with a higher bodyweight during adolescence. (kreftregisteret.no)
  • The Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY) trial is the first ever international multi-center randomized controlled trial in bone cancer surgery. (stanford.edu)
  • In order to avoid amputation for bone cancer in the leg, complex limb-saving operations are performed. (stanford.edu)
  • Pediatric radiation therapy survivors incur risk for radiation-induced hematological malignancies related to red bone marrow (RBM) dose. (appliedradiationoncology.com)
  • Survivors of CNS and bone tumors report their physical health-status to be importantly below population norms. (ox.ac.uk)
  • Grade III bone cement implantation syndrome in malignant lung cancer patient: a case report. (medscape.com)
  • I am sure that the programme of Torino meeting was of interest for everyone connected to PanCare: Survivors, Parents, Researchers, Healthcare professionals and everyone else that is interested. (pancare.eu)
  • Postdiagnosis dietary factors, supplement use and breast cancer prognosis: Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis. (who.int)
  • Postdiagnosis recreational physical activity and breast cancer prognosis: Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis. (who.int)
  • Postdiagnosis body fatness, recreational physical activity, dietary factors and breast cancer prognosis: Global Cancer Update Programme (CUP Global) summary of evidence grading. (who.int)
  • In particular, female survivors of childhood cancer with SBC have a significantly increased 10-year mortality risk as compared with women with de novo breast cancer. (medpagetoday.com)
  • Therefore, the types of ious forms of radiation, carcinogen ifested as a higher incidence of the tumours that occur during childhood ic infectious agents, and chemicals same kinds of tumours that occur in in humans, including various embry and chemical mixtures. (who.int)
  • 10, 15 years ago many of the survivors received chest radiation, and thoracic radiation that included the chest and neck. (oncologytube.com)
  • Radiation safety standards are derived from studies of the A-bomb survivors of Hiroshima and Nagasaki. (ratical.org)
  • When it was found that a small number of the A-bomb survivors were living longer than they ought to, this was seen as proof that radiation had done them good. (ratical.org)
  • It shows that cancer was not the only effect of the A-bomb radiation. (ratical.org)
  • This means that we cannot base standards of radiation safety on such an elite cohort. (ratical.org)
  • Excess-radiation-induced hematological malignancies (eg, acute myeloid leukemia) have been observed in survivors of pediatric radiation therapy. (appliedradiationoncology.com)
  • This trend was also significant for those treated with therapies associated with substantial risk for cardiovascular disease or breast cancer. (nih.gov)
  • This continues to be an issue for understanding effects of new anti-cancer therapies such as immunotherapy, CDK4/6 inhibitors and PARP inhibitors on fertility. (cancer.org.au)
  • Consequently, the findings are difficult to interpret within the context of modern therapies for childhood cancers. (medpagetoday.com)
  • Thanks to improved therapies, the proportion of survivors after childhood cancer has continuously been increasing in recent decades. (unimedizin-mainz.de)
  • Survivors of childhood Hodgkin's Lymphoma have been an unrecognized group for a number of years because they don't receive direct neurotoxic therapies. (oncologytube.com)
  • 09.25-09.45 Childhood leukaemias and CNS tumours: correlation of international incidence rates . (bmj.com)
  • The annual US incidence of tobacco-related cancers is approximately 500,000 [ 9 ]. (cdc.gov)
  • This paper presents the incidence of cancer in Jordan from 1996 to 2005. (who.int)
  • A high incidence of breast cancer was found in Israeli Jews compared with Arab populations and these differences provide an example of the potential role of lifestyle and genetic factors in the etiology of breast cancer [3]. (who.int)
  • Prevalence of SARS-CoV-2 specific neutralising antibodies in blood donors from the Lodi Red had no cancer history. (cdc.gov)
  • We used 2009 Behavioral Risk Factor Surveillance System data to describe demographic characteristics, smoking history, current smoking prevalence, and smokeless tobacco use among TRCS, other cancer survivors, and people without a history of cancer (cigarette smoking and smokeless tobacco use were calculated after adjusting for age, sex, race, and insurance status). (cdc.gov)
  • The self-reported smoking prevalence among TRCS is higher than among other cancer survivors and people without a history of cancer. (cdc.gov)
  • Nevertheless, the prevalence of smoking among cancer survivors is similar to that of the general population [ 13 - 18 ]. (cdc.gov)
  • citation needed] For this reason, childhood cancer is often ignored in control planning, contributing to the burden of missed opportunities for its diagnoses and management in countries that are low- and mid-income. (wikipedia.org)
  • This is largely due to more cancer diagnoses as a result of an aging population and improvements in early detection and treatment of cancer [ 5 , 6 ]. (cdc.gov)
  • [7] These systematic reviews report mainly retrospective cohort studies (Level III evidence) but together provide good evidence that people treated for cancer are less likely to conceive and give birth. (cancer.org.au)
  • Further evidence for lower conception and birth rates for people diagnosed with cancer comes from sub-studies of the Childhood Cancer Survivors Cohort. (cancer.org.au)
  • Risks associated with being a young cancer survivor were emphasized by two studies highlighted in press briefings at the 2012 ASCO Annual Meeting. (ascopost.com)
  • Low birthweight, poor childhood growth, emotional stress at a young age, lower socioeconomic position and environmental toxins are factors identified in some but not all studies 4 . (menopause.org.au)
  • Background: Questionnaires are widely used in survey research, especially in cohort studies. (websm.org)
  • The work is the latest in a series of studies searching for genetic- or treatment-related contributors to secondary cancer or benign tumor development in individuals treated for cancer as children or young adults. (genomeweb.com)
  • The researchers found that childhood cancer survivors who were diagnosed before the age of five are at the highest risk for a severe mental health event: by age 28, 16 per cent of these adults will have had an ED visit or hospitalization for mental health reasons. (ices.on.ca)
  • The researchers found childhood cancer survivors had a 34 per cent higher rate of medical visits for a mental health complaint compared to the general population and most visits were to family physicians and psychiatrists. (ices.on.ca)
  • In this technique, the researchers compare the DNA variants present in survivors and community controls with different levels of biological aging (i.e. (medicalxpress.com)
  • Researchers are unsure what exactly causes chemo brain, however, they say it is likely to be linked to either the cancer itself, the cancer treatment, or be an emotional reaction to both. (wikipedia.org)
  • Demographic, self-reported modifiable lifestyle (ie, smoking, alcohol, physical activity, and BMI) and cardiovascular risk factors (ie, hypertension, diabetes, and dyslipidaemia) associated with health-related mortality (which excludes death from primary cancer and external causes and includes death from late effects of cancer therapy) were evaluated. (duke.edu)
  • In our research we have been able to show that a longitudinal, systematic neuropsychological follow-up is essential after pediatric brain tumor, both in terms of finding individuals with rehabilitation need and in terms of evaluating the cancer treatment given with respect to cognitive sequelae. (lu.se)
  • Children with cancer should be monitored and assessed for these neuropsychological deficits during and after treatment. (wikipedia.org)
  • Fertility preservation in adolescents and young adults with cancer. (cancer.org.au)
  • Dr. Kirchhoff has a strong history of funding as a Principal Investigator from both institutional grant support and external funding via the NIH and foundations, including an NCI R01 to develop and test insurance educational materials for adolescents and young adults with cancer. (utah.edu)
  • We examined the trends in primary hospitalisations for physical disease in a whole-population cohort of 5-year childhood cancer survivors (CCS) diagnosed in Western Australia (WA) from 1982-2014. (authorea.com)
  • We see that the impairment since Hodgkin's Lymphoma survivors are diagnosed during adolescence they can often get through primary school. (oncologytube.com)
  • It is now generally recognized that surviving childhood cancer requires follow-up care by an integrated team that includes qualified and invested specialists as well as primary caregivers. (medscape.com)
  • These teams deliver care with a risk-based approach, following a systemic plan for lifelong screening, surveillance, and prevention that incorporates risks based on the previous cancer, cancer therapy, genetic predispositions, lifestyle behaviors, and comorbid health conditions. (medscape.com)
  • We describe tobacco use behaviors among TRCS, other cancer survivors, and people without a history of cancer. (cdc.gov)
  • We provide the first population-based report on demographic characteristics and tobacco use behaviors among self-reported tobacco-related cancer survivors. (cdc.gov)
  • The pregnancy rate for women treated for breast cancer is on average 40% lower than the general population. (cancer.org.au)
  • Overall, women who survived childhood cancers had an increased risk of breast cancer versus an age/sex/calendar year-matched population. (medpagetoday.com)
  • However, the rate of invasive breast cancer decreased by 18% for each 5-year diagnostic period for childhood cancers. (medpagetoday.com)
  • These findings provide important insight into temporal patterns in treatment-associated breast cancer risk. (medpagetoday.com)
  • 10.40-11.00 Adherence to tamoxifen and recurrence of and mortality from breast cancer . (bmj.com)
  • Physical Activity and Risk of Male Breast Cancer. (kreftregisteret.no)
  • Prediagnostic Sex Steroid Hormones in Relation to Male Breast Cancer Risk. (kreftregisteret.no)
  • Postdiagnosis body fatness, weight change and breast cancer prognosis: Global Cancer Update Program (CUP global) systematic literature review and meta-analysis. (who.int)
  • Physical Activity and Health-Related Quality of Life in Women With Breast Cancer: A Meta-Analysis. (who.int)
  • Metabolomic profiles of metformin in breast cancer survivors: a pooled analysis of plasmas from two randomized placebo-controlled trials. (who.int)
  • Wilms tumor, or nephroblastoma, is the most common childhood abdominal malignancy. (medscape.com)
  • Through using a well-characterised cohort of 5-year survivors of the most common childhood cancers, we evaluated specific health-related causes of late mortality and excess deaths compared with the general US population and identified targets to reduce future risk. (duke.edu)
  • However, the definition of childhood cancer sometimes includes adolescents between 15 and 19 years old. (wikipedia.org)
  • This cognitive impairment is commonly noticed a few years after a child endures cancer treatment. (wikipedia.org)
  • So I'm the Medical Director of the World Trade Center Environmental Health Center for the survivors and community members, and my background, as you've heard, is really I began as an asthma doctor, asthma and environmental issues were my interest, and I've been at NYU and at Bellevue and at Health + Hospitals for many, many, many years, and I'm now a professor there. (cdc.gov)
  • In order to discuss fertility with patients, it is important to understand the impact of cancer treatment on fertility and the chance of conceiving a child naturally. (cancer.org.au)
  • That's not an option for pre-pubescent cancer patients, though, as their bodies haven't started producing sperm yet. (freethink.com)
  • Childhood cancer patients might not have sperm yet, but their testicular tissue does contain the spermatogonial stem cells (SSCs) that will evolve to produce sperm post-puberty. (freethink.com)
  • This led to the idea that it might one day be possible to restore fertility in childhood cancer patients by removing a bit of a testicular tissue prior to treatment and reimplanting it once they were an adult. (freethink.com)
  • In 2002, UZ Brussels - the university hospital of the VUB - started offering testicular tissue banking to the parents of young cancer patients. (freethink.com)
  • Since we were the first worldwide to offer testicular tissue banking to prepubescent boys, we now have the oldest cohort, including patients in their mid-twenties," Goossens told New Scientist. (freethink.com)
  • To promote timely cervical cancer screening and prevent retraumatization of patients with a history of ACEs, providers should implement trauma-informed care principles in their healthcare settings. (ons.org)
  • Despite these challenges, outcome for pediatric cancer is good, with 80-85% of patients surviving. (lu.se)