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  • upstream
  • When translating ribosomes encounter a stop codon upstream of an EJC, the recruitment of UPF1 by translation release factors leads to an interaction with the UPF2 and UPF3 proteins bound to the downstream EJC, and thus to the assembly of the surveillance complex and to mRNA degradation (reviewed by Lejeune and Maquat, 2005 ). (embopress.org)
  • proteins
  • The codons are essentially the instructions for cells to create the proteins needed to create life, forming the basis of cell communication. (reference.com)