• While misuse of synthetic opioids such as fentanyl appears to be more common, according to the 2020 National Survey on Drug Use and Health, 8.9% of people misused morphine and 12.2% misused codeine in 2020. (medicalnewstoday.com)
  • Morphine belongs to a class of drugs known as opioid analgesics. (webmd.com)
  • Codeine sulfate is an opioid analgesic (pain reliever) drug used to treat mild to moderate pain. (rxlist.com)
  • Codeine sulfate is an opioid analgesic indicated for the relief of mild to moderately severe pain where the use of an opioid analgesic is appropriate. (rxlist.com)
  • Selection of patients for treatment with codeine sulfate should be governed by the same principles that apply to the use of similar opioid analgesics. (rxlist.com)
  • Avoid the use of acetaminophen/caffeine/dihydrocodeine bitartrate in adolescents 12 to 18 years of age who have other risk factors that may increase their sensitivity to the respiratory depressant effects of codeine. (drugs.com)
  • Use of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with acetaminophen/caffeine/dihydrocodeine bitartrate requires careful consideration of the effects on the parent drug, codeine, and the active metabolite, morphine. (drugs.com)
  • Codeine is also used to control coughing that is not controlled by non-narcotic cough suppressants. (medbroadcast.com)
  • Most of the reported cases occurred following tonsillectomy and/or adenoidectomy, and many of the children had evidence of being an ultra-rapid metabolizer of codeine due to a CYP2D6 polymorphism. (drugs.com)
  • 001). From 2% to 6% of the morphine groups reported nausea, abdominal pain, and drowsiness, whereas none of those in the ibuprofen-only group reported those symptoms. (medscape.com)
  • Interactions with Drug Affecting Cytochrome P450 Isoenzymes: The effects of concomitant use or discontinuation of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with codeine are complex. (drugs.com)
  • Respiratory depression and death have occurred in children who received codeine following tonsillectomy and/or adenoidectomy and had evidence of being ultra-rapid metabolizers of codeine due to a CYP2D6 polymorphism. (rxlist.com)
  • Codeine has less pain-relieving and sedative properties, so doctors usually use it to treat a cough. (medicalnewstoday.com)
  • The recommended adult dose of codeine as a cough suppressant is 15 mg to 30 mg every 6 to 8 hours as needed, up to a maximum of 120 mg daily. (medbroadcast.com)
  • In general codeine should be used at the lowest dose that provides relief for the shortest duration of time possible. (medbroadcast.com)
  • The recommended dose of codeine for pain relief for is 15 mg to 60 mg every 4 to 6 hours as required , not to exceed 360 mg in one day. (medbroadcast.com)
  • The authors mentioned that the lack of difference between groups may be related to the morphine dose used in the study (0.2 mg/kg). (medscape.com)
  • The usual adult dosage for codeine sulfate tablets is 15 mg to 60 mg repeated up to every four hours as needed for pain. (rxlist.com)
  • snort morphine tablets or capsules in an effort to enhance its effects). (drugabuse.com)
  • Morphine is commonly given to patients before and after surgical procedures to reduce pain. (livescience.com)
  • The study looked at three ways of relieving pain - combined oral morphine with oral ibuprofen, oral morphine alone, and oral ibuprofen alone - and found that none of these medications was optimal for treating acute musculoskeletal pain in the children's ED. (medscape.com)
  • Ultra-Rapid Metabolism of Codeine and Other Risk Factors for Life-Threatening Respiratory Depression in Children: Life-threatening respiratory depression and death have occurred in children who received codeine. (drugs.com)
  • Our Codeine sulfate Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
  • Codeine is no longer recommended for children, due to the increased risk of breathing difficulty and other complications of this medication. (medbroadcast.com)
  • Each tablet contains 15, 30, or 60 mg of codeine sulfate and the following inactive ingredients: colloidal silicon dioxide, microcrystalline cellulose, pregelatinized starch, and stearic acid. (rxlist.com)
  • An opiate is any natural or synthetic drug that has morphine-like pharmocological actions. (fda.gov)
  • Codeine should be used during pregnancy only if the potential benefit justifies the potential risk. (rxlist.com)
  • Combined oral morphine plus oral ibuprofen does not provide adequate pain relief in children with musculoskeletal injuries treated in the emergency department (ED), according to results from the OUCH trial published online October 11 in Pediatrics . (medscape.com)
  • The use of codeine sulfate by some nursing mothers may lead to life-threatening side effects in the baby. (rxlist.com)