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  • phospholipase
  • But the AACE encourages looking at the inflammatory markers highly sensitive C-reactive protein (hsCRP) and in some patients lipoprotein-associated phospholipase A2 (Lp-PLA2), when risk is uncertain and additional information is needed to decide how aggressively to treat. (thefreedictionary.com)
  • Venom Proteins
  • 80% of gel spots from 2DE displayed high-quality MALDI-TOF-MS spectra, only 50% of these spots were confirmed to be venom proteins, which is more than likely to be a result of incomplete protein databases. (biology-online.org)
  • Anticoagulant action of snake venom proteins is attributed to: (i) the activation of protein C, (ii) the inhibition of blood coagulation factors IX and X by a venom protein that binds to either or both clotting proteins, (iii) a thrombin inhibitor and (iv) phospholipases that degrades phospholipids involved in the formation of complexes critical to the activation of the coagulation pathway . (scidoc.org)
  • Rats
  • We have previously reported that cobratoxin (CTX), the long-chain α -neurotoxin from Thailand cobra venom, had anti-inflammatory and antinociceptive effects on adjuvant arthritis [ 6 ] and can relieve the formalin-induced inflammatory pain in rats [ 7 ]. (hindawi.com)
  • gene
  • Since the pairings of splice sites and gene architecture were supposed to be associated with intron-exon recognition, it is likely that the preferred loci of mutations occurring with the evolution of cardiotoxin genes would not affect the processing of cardiotoxin precursors. (antibody-antibodies.com)
  • heparin
  • Lee SC, Guan HH, Wang CH. Structural basis of citrate-dependent and heparin sulfate-mediated cell surface retention of cobra cardiotoxin A3. (springer.com)
  • In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity. (uniprot.org)
  • Actions
  • Cobratoxin, a long-chain neurotoxin, from Thailand cobra venom has been demonstrated to have potent actions on inhibiting formalin-induced inflammatory pain [ 19 ] and adjuvant arthritis [ 20 ]. (hindawi.com)
  • processes
  • Podocyte foot processes acted as the main component of glomerular filtration barrier preventing excessive proteins from leaking out [ 10 , 11 ]. (hindawi.com)
  • A better understanding of the processes and proteins involved in myogenesis and muscle regeneration may enable the design of innovative therapies to improve the care of victims of severe muscle trauma, patients with skeletal myopathies, and the elderly. (pnas.org)
  • residue
  • Compared to the natural protein, it contains an additional Met residue at the N-terminus. (ibch.ru)
  • small
  • In an attempt to understand how a protein so small and highly charged can overcome the gradient of charge-charge repulsions and aggregate, we have begun a series of detailed investigations. (biomedcentral.com)
  • function
  • Nephrin protein was identified in SD and participated in maintaining the structure and function of podocytes [ 13 ]. (hindawi.com)
  • role
  • These are actually hyrdolases that primarily act to breakdown proteins, by hydrolysis and thus are proteolytic and serve a digestive role. (serpentoxin.com)