A small percentage of G6PD-deficient patients have chronic nonspherocytic hemolytic anemia (CNSHA) of variable severity. (medscape.com)
Chronic nonspherocitic hemolytic anemia (CNSHA) and Glucose 6 phosphate dehydrogenase (G6PD) deficiency in a patient with familial amyloidotic polyneuropathy (FAP). (cellsilab.com)
Sporadic cases of glucose 6-phosphate dehydrogenase deficiency occur at a very low frequencies, and they usually present a more severe phenotype, namely chronic nonspherocytic hemolytic anemia (CNSHA). (lu.se)
Haemolytic anaemia1
variants that cause chronic non-spherocytic haemolytic anaemia (CNSHA) are instead all rare. (bvsalud.org)
Variants2
There is a direct relationship between residual G6PD activity and substrate affinity (Km G6P ), suggesting a mechanism whereby polymorphic G6PD deficient variants do not entail CNSHA. (bvsalud.org)
The C-->T transition responsible for GGPD Bari maps close to several other mutations previously identified in GGPD variants associated with CNSHA. (cnr.it)
G6PD1
We have used the polymerase chain reaction and nucleotide sequence analysis to characterize a new G6PD variant, which we designate as G6PD Bari, in a G6PD-deficientt boy affected by CNSHA. (cnr.it)