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  • cells
  • However these factors were not upregulated during regeneration as would be expected if blastema cells acquired pluripotency. (biomedcentral.com)
  • By comparing cells from the regeneration blastema with embryonic pluripotent reference cells we found that induced pluripotent stem and blastema cells do not share pluripotency. (biomedcentral.com)
  • We therefore propose a link between partially reprogrammed induced pluripotent stem cells and the half way state of blastema cells and suggest that a common mechanism might be regulating these two processes. (biomedcentral.com)
  • After the loss of an appendage undifferentiated, pluri- or multipotent cells from different origins accumulate at the damaged surface to form a regeneration blastema. (biomedcentral.com)
  • Despite the heterogeneous origin of the blastema cells, histologically they appear as a homogeneous population of cells and therefore have been traditionally viewed as a single cell type. (biomedcentral.com)