• It is closely related to B. pseudomallei, and by multilocus sequence typing it is a subspecies of B. pseudomallei. (wikipedia.org)
  • B. mallei evolved from B. pseudomallei by selective reduction and deletions from the B. pseudomallei genome. (wikipedia.org)
  • B. mallei is very closely related to B. pseudomallei, being 99% identical in conserved genes when compared to B. pseudomallei. (wikipedia.org)
  • B. mallei may have actually evolved from a strain of B. pseudomallei after the latter had infected an animal. (wikipedia.org)
  • This suggestion has found support from studies that compare strains of B. mallei to B. pseudomallei and indicate that their two respective genomes are very similar. (wikipedia.org)
  • Multilocus sequence typing has revealed that B. mallei most likely evolved from a B. pseudomallei clone reduction. (wikipedia.org)
  • No standardised system exists for differentiating between B. mallei and B. pseudomallei. (wikipedia.org)
  • Comparing the DNA of B. mallei and B. pseudomallei must be done at the 23S rDNA level, however, since no identifiable difference is found between the two species at the 16S rDNA level. (wikipedia.org)
  • These diseases are caused by closely related Gram-negative bacteria named Burkholderia (B.) mallei and B. pseudomallei, respectively. (ufl.edu)
  • His Microbiology study integrates concerns from other disciplines, such as Virology, Secondary metabolite and Burkholderia pseudomallei. (research.com)
  • The facultative, intracellular bacterium Burkholderia pseudomallei is the causative agent of melioidosis, a serious infectious disease of humans and animals. (biomedcentral.com)
  • Multilocus variable number tandem repeat analysis of a Burkholderia mallei strain isolated from a diseased dromedary in Bahrain revealed close genetic proximity to strain Dubai 7, which caused an outbreak of glanders in horses in the United Arab Emirates in 2004. (cdc.gov)
  • Glanders, a World Organisation for Animal Health (OIE)-listed disease, is a contagious, life-threatening disease of equids caused by the gram-negative bacterium Burkholderia mallei ( 1 ). (cdc.gov)
  • In addition to horses and donkeys, dromedaries showed clinical signs of glanders, but B. mallei infection has not yet been confirmed. (cdc.gov)
  • The genes that allowed the bacterium to survive in a soil environment, like genes that gave B. mallei the capacity to protect against bactericidals, antibiotics, and antifungals, were likely deleted. (wikipedia.org)
  • Genome comparisons also seem to indicate that the B. mallei is still evolving and adapting to an intracellular lifestyle. (wikipedia.org)
  • The genome of B. mallei was sequenced in the United States by The Institute of Genomic Research. (wikipedia.org)
  • The genome for B. mallei is made up of two circular chromosomes. (wikipedia.org)
  • About 1000 B. pseudomellei genes are absent or varying in the B. mallei genome. (wikipedia.org)
  • His Genome research focuses on Aspergillus nidulans and how it relates to Metabolic engineering, Penicillin and Penicillium chrysogenum. (research.com)
  • His research in Genome tackles topics such as Burkholderia contaminans which are related to areas like Horizontal gene transfer and Antibiotic sensitivity. (research.com)
  • the Latin name of this disease (malleus) gave its name to the species causing it. (wikipedia.org)
  • Many microbiologists are unfamiliar with B. mallei and as a result it has frequently been misidentified as a Pseudomonas species or as a contaminant in a culture. (wikipedia.org)
  • About 100 species have been described within genus Burkholderia , which is related to genus Taylorella . (slu.se)
  • The two species of genus Burkholderia , which have beebn included in VetBact, are very closely related. (slu.se)
  • An understanding of the β-lactamases in other related species is importa. (biomedcentral.com)
  • The API 20 NE-test identified the colonies as B. mallei because the same API ID number (1140504) occurred as in the previously isolated Dubai 7 strain ( 1 ). (cdc.gov)
  • Burkholderia mallei was first called "Bacillus mallei" and was in the genus Pseudomonas until the early 1990s. (wikipedia.org)
  • Suspected B. mallei colonies were analyzed with the API 20 NE-test (bioMérieux, Marcy l'Etoile, France) and were positive for nitrate, glucose assimilation, arginine dehydrolase (after 4 days of incubation), N-acetyl glucosamine, and potassium gluconate. (cdc.gov)
  • Camels are also susceptible to B. mallei , as experimental infection has demonstrated ( 4 , 5 ). (cdc.gov)
  • Here we provide evidence for a B. mallei infection in 1 of the diseased dromedaries. (cdc.gov)
  • Enter search terms to find related veterinary topics, multimedia and more. (msdvetmanual.com)
  • Chromosome 1 is where genes relating to metabolism, capsule formation, and lipopolysaccharide biosynthesis are located. (wikipedia.org)
  • Thus, the reason that B. mallei is not found outside of a host is because it lacks the genes necessary for survival in the soil. (wikipedia.org)
  • His Gene study frequently links to related topics such as Microbiology. (research.com)
  • His Microbiology study combines topics in areas such as Phenotype, Aspergillosis and Burkholderia. (research.com)
  • Burkholderia mallei belongs to category B as a potential bioterrorism agent according to NIAID. (slu.se)
  • B. mallei culture growth on MacConkey agar is variable. (wikipedia.org)
  • B. mallei has a polysaccharide capsule which indicates its potential as a pathogen. (wikipedia.org)
  • Permits for Blasting are issued by the State Fire Marshal (Western Regional Office 301-791-4758) or Baltimore Office of the State Fire Marshal (410-875-5450) Issues or concerns relating to blasting on private property should be referred or forwarded to the State Fire Marshal Fire Marshal (either office). (cityoffrederickmd.gov)
  • His Gene cluster study is related to the wider topic of Gene. (research.com)