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  • nuclear
  • A year ago, Mitalipov led the team that used nuclear transfer of fetal and infant DNA to produce stem cells, the first time that had been accomplished in humans of any age. (stabroeknews.com)
  • Earlier in this blog, I indicated that DNA rearrangements and deletions during cellular differentiation may make nuclear compartments unavailable to be used for cloning specific kinds of stem cells because all of the DNA is not there. (wordpress.com)
  • While attending the Medical College of Virginia, Wood researched isolating a DNA nuclear matrix of HeLa cells using a poly(dT) template. (wikipedia.org)
  • experiments
  • First of all, most cloning experiments are highly inefficient, meaning that only a few percent of the attempts are ever successful. (wordpress.com)
  • Gurdon began cloning experiments using nonembryonic cells-specifically, cells from the intestinal lining of tadpoles. (blogspot.com)
  • But the tadpoles cloned in Gurdon's early experiments never survived to adulthood and scientists now believe that many of the cells used in these experiments may not have been differentiated cells after all. (blogspot.com)
  • Gurdon's recent research has focused on analyzing inter cellular signal ling factors involved in cell differentiation, and on elucidating the mechanisms involved in reprogramming the nucleus in transplantation experiments, including demethylation of the transplanted DNA. (blogspot.com)
  • Many scientists believe that, at least in the near future, experiments in human cloning would involve many failures, miscarriages, stillbirths, and the birth of deformed babies. (encyclopedia.com)
  • He was a professor of theriogenology and biotechnology at Seoul National University (dismissed on March 20, 2006) who became infamous for fabricating a series of experiments, which appeared in high-profile journals, in the field of stem cell research. (wikipedia.org)
  • Shortly after that his human cloning experiments were revealed to be fraudulent. (wikipedia.org)
  • embryonic stem
  • In 2011, scientists at the New York Stem Cell Foundation announced that they had succeeded in generating embryonic stem cell lines, but their process involved leaving the oocyte's nucleus in place, resulting in triploid cells, which would not be useful for cloning. (wikipedia.org)
  • Because of their plasticity and potentially unlimited capacity for self-renewal, embryonic stem cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease. (wikipedia.org)
  • donor
  • That now looks possible, though far from easy: Out of 39 tries, the scientists created stem cells only once for each donor. (stabroeknews.com)
  • Theoretically, tissues generated from cells cloned from a patient's own adult nucleus should not trigger an immune response, but it is possible that subtle differences caused by the foreign cytoplasm in the donor egg might cause a rejection response. (encyclopedia.com)
  • Embryonic stem cells provide hope that it will be possible to overcome the problems of donor tissue shortage and also, by making the cells immunocompatible with the recipient. (wikipedia.org)
  • patient's
  • NEW YORK, (Reuters) - Scientists have moved a step closer to the goal of creating stem cells perfectly matched to a patient's DNA in order to treat diseases, they announced yesterday, creating patient-specific cell lines out of the skin cells of two adult men. (stabroeknews.com)
  • scientists
  • A team of biotechnology scientists led by Suresh K Singla, were involved in the successful cloning procedure. (ibtimes.co.in)
  • Unlike, other clones produced by the NDRI scientists, Lalima did not show any symptom of abnormal calf. (ibtimes.co.in)
  • S Ayyappan, director general of Indian council of agricultural research (ICAR), while congratulating the scientists on their achievement on producing cloned calf from mature lactating animal though "hand-guided cloning" technique said it would definitely aid in multiplication of elite lactating animals and would reduce the ever increasing demand of milk. (ibtimes.co.in)
  • Despite more than 15 years of trying, scientists' single success at producing human stem cells through this cloning technique came a year ago. (stabroeknews.com)
  • The scientists tried cloning adult cells, but those attempts failed. (nytimes.com)
  • If scientists wanted to create a monkey identical to an adult, or even an adolescent, this method so far would not succeed. (nytimes.com)
  • Although scientists at Duke University suggested that human clones might not experience the problems encountered in cloned animals, the risks remains very high and quite unpredictable. (encyclopedia.com)
  • Although the possibility of cloning humans had been the subject of speculation for much of the 20th century, scientists and policy makers began to take the prospect seriously in the mid-1960s. (wikipedia.org)
  • Many nations outlawed it, while a few scientists promised to make a clone within the next few years. (wikipedia.org)
  • genetic
  • Many of the surviving clones are plagued with serious physiological and genetic problems. (encyclopedia.com)
  • It is not yet known whether clones will develop and age normally, or whether subtle failures in genomic reprogramming or genetic imprinting might lead to various defects. (encyclopedia.com)
  • Nobel Prize-winning geneticist Joshua Lederberg advocated cloning and genetic engineering in an article in The American Naturalist in 1966 and again, the following year, in The Washington Post. (wikipedia.org)
  • Other potential uses of embryonic stem cells include investigation of early human development, study of genetic disease and as in vitro systems for toxicology testing. (wikipedia.org)
  • defects
  • These defects in cell migration among medulla cortex cells can be rescued by removing D E-Cadherin. (biologists.org)
  • Clones are often born with a condition called "large offspring syndrome," as well as severe respiratory and circulatory defects, malformations of the brain or kidneys, or immune dysfunction. (encyclopedia.com)
  • biologist
  • Stem cell biologist George Daley of the Harvard Stem Cell Institute called it "an incremental advance" and "not earth-shattering. (stabroeknews.com)
  • I am a retired cell biologist and alumnus of Ohio State University. (wordpress.com)
  • In 1963 the British biologist J. B. S. Haldane, in describing Gurdon's results, became one of the first to use the word clone in reference to animals. (blogspot.com)
  • world's
  • The calf named 'Lalima' is the world's first clone to be produced using cells of an adult buffalo. (ibtimes.co.in)
  • On November 2015, a Chinese biotech company Boyalife Group announced that it will partner with Hwang's laboratory, Sooam Biotech, to open the world's largest animal cloning factory in Tianjin as early as 2016. (wikipedia.org)
  • nucleus
  • He then removed the nucleus from the tadpole intestinal cell and implanted it in the enucleated egg. (blogspot.com)
  • diseases
  • Cloned cells could be used to create replacement tissue for diseased hearts, pancreatic cells for diabetics, treatments for neurodegenerative diseases, such as Parkinson's and Alzheimer's, nerve cells for victims of spinal cord injuries, and skin cells for burn victims. (encyclopedia.com)
  • tissue
  • The term is generally used to refer to artificial human cloning, which is the reproduction of human cells and tissue. (wikipedia.org)
  • According to a 2002 article in PNAS, "Human embryonic stem cells have the potential to differentiate into various cell types, and, thus, may be useful as a source of cells for transplantation or tissue engineering. (wikipedia.org)
  • For example, studies are underway to differentiate ES in to tissue specific CMs and to eradicate their immature properties that distinguish them from adult CMs. (wikipedia.org)
  • eggs
  • He and his colleagues removed skin cells from a 9-year-old macaque and inserted them into eggs from which the original DNA had been removed. (nytimes.com)
  • Dr. Wood and a colleague donated skin cells, and DNA from those cells was transferred to human eggs. (wikipedia.org)
  • Hwang explained that his team used 242 eggs to create a single cell line. (wikipedia.org)
  • Dr. Wood and a colleague donated skin cells and the DNA from those cells was transferred into human eggs. (wikipedia.org)
  • genes
  • But with our latest technique, where somatic cells present in the ear were used, the clone will get genes of the female only. (ibtimes.co.in)
  • We also show that one of the genes, ey / Pax6 , is expressed in OPC neuroblasts and controls migration of a subpopulation of cells in the optic lobe. (biologists.org)
  • notable
  • Stemagen is a corporation headed by Dr. Samuel Wood, notable for cloning adult skin cells. (wikipedia.org)
  • His alleged success was touted as the fifth instance in the world in cow cloning, with a notable caveat: Hwang failed to provide scientifically verifiable data for the research, giving only media sessions and photo-ops. (wikipedia.org)
  • technique
  • In 2013, a calf was produced using the similar cloning technique but the clone survived only for three weeks after suffering from various ailments since its birth. (ibtimes.co.in)
  • Divide
  • The hybrid cell is then stimulated to divide by an electric shock, and when it develops into a blastocyst it is implanted in a surrogate mother. (wikipedia.org)
  • animal
  • Again, the short answer is that most of these cells are adult stem cells that are in fact missing some of the DNA required to make a complete animal. (wordpress.com)
  • Eventually animal research may indicate that human cloning can be accomplished with no greater risk than in vitro fertilization posed when Louise Brown, the first "test-tube baby" was born in 1978. (encyclopedia.com)
  • So-called "testis" in an adult animal is a receptacle of cells from larval males. (wikipedia.org)
  • Hwang
  • On May 12, 2006, Hwang was charged with embezzlement and bioethics law violations after it emerged much of his stem cell research had been faked. (wikipedia.org)
  • In February 2011, Hwang visited Libya as part of a $133 million project in the North African country to build a stem cell research center and transfer relevant technology. (wikipedia.org)
  • During that period, Hwang claimed to have created a BSE-resistant cow (which has not been verified) and also stated his intention to clone a Siberian tiger. (wikipedia.org)
  • bulls
  • The aim behind the buffalo cloning is to produce clone of offspring tested bulls and buffaloes yielding high lactation, said Srivastava while announcing the achievement. (ibtimes.co.in)
  • Korean
  • The Korea Times reported on June 10, 2007, that Seoul National University fired him, and the South Korean government canceled his financial support and barred him from engaging in stem cell research. (wikipedia.org)
  • generate
  • White and Kankel, 1978 ), generate the correct number of cells present in the adult optic lobe: the IPC gives rise to neurons of the lobula complex and proximal medulla (presumably cells from the medulla rim), while the OPC generates most medulla neurons (presumably cells from the medulla cortex) as well as cells that will generate the lamina ( Meinertzhagen and Hanson, 1993 ). (biologists.org)
  • while embryonic stem cells can generate all cell types in the body, adult stem cells are multipotent and can produce only a limited number of cell types. (wikipedia.org)
  • neuronal
  • Strausfeld, 1976 ), and identified at least 63 distinct neuronal cell types that express these transcription factors in the medulla and might be involved in processing of visual information ( Morante and Desplan, 2008 ). (biologists.org)
  • In 1921 Otto Loewi provided the first substantial evidence that neuronal communication with target cells occurred via chemical synapses. (wikipedia.org)