• This review summarizes evidence for the role of proteolytic enzymes that degrade and inactivate insulin-like growth factor binding proteins (IGFBP) during follicular development in mammals. (bioone.org)
  • In this minireview we examine the structure, expression patterns, and biological actions of the PRL and GH families from rodents (primarily rat and mouse), ruminants (primarily ovine and bovine), and primates (primarily human). (biomedcentral.com)
  • Lists of PRL and GH family members from the mouse and rat, bovine and ovine, and human and rhesus monkey are provided in Tables 1 , 2 and 3 . (biomedcentral.com)
  • Members of the human GH family are closely related structural variants, whereas members of the rat, mouse, and bovine PRL families exhibit considerable sequence diversity. (biomedcentral.com)
  • However, offspring of cloned mice and cloned cattle conceived naturally appear to have been largely normal, suggesting that developmental problems seen in cloned animals do not arise through gene abnormalities, but because the mechanisms controlling foetal development are not operating properly. (thehumangenome.co.uk)
  • They think extraordinary thoughts, and sometimes - this is the privilege of the job - they are able to turn those thoughts into reality….As the decades and centuries pass, the science of cloning and the technologies that may flow from it will affect all aspects of human life - the things that people can do, the way we live, and even, if we choose, the kinds of people we are. (thehumangenome.co.uk)
  • NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (nih.gov)
  • Regulating cloning and embryo stem cell research - The various approaches taken to regulate cloning and embryonic stem cell research mirror the ethical debates. (thehumangenome.co.uk)
  • In relation to therapeutic cloning, some countries do not allow the creation of embryos for research (allowing only research on IVF embryos) or do not allowany research on embryos at all, and thereby implicitly do not allow the production of a cloned embryo. (thehumangenome.co.uk)