Loading...
  • world's
  • From eGenesis's tiny headquarters in Kendall Square, she intends to use CRISPR to accomplish what the world's largest drug companies failed to despite investing billions of dollars: create "designer pigs" whose organs can be transplanted into people. (scientificamerican.com)
  • On November 2015, a Chinese biotech company Boyalife Group announced that it will partner with Hwang's laboratory, Sooam Biotech, to open the world's largest animal cloning factory in Tianjin as early as 2016. (wikipedia.org)
  • April 24, 2005-May 2015) was an Afghan hound, credited with being the world's first cloned dog. (wikipedia.org)
  • 1999
  • Hwang's next claim came only two months later in April 1999, when he announced the cloning of a Korean cow, Jin-i, also without providing any scientifically verifiable data. (wikipedia.org)
  • A Holstein heifer named Daisy was cloned by Dr. Xiangzhong (Jerry) Yang using ear skin cells from a high-merit cow named Aspen at the University of Connecticut in 1999, followed by three additional clones, Amy, Betty, and Cathy in 1999. (wikipedia.org)
  • Genome
  • Evolutionary biologist Beth Shapiro points out that "cloning" is a specific technique which cannot be accomplished without a living cell, none of which are available for mammoths, but suggests genome editing might be feasible. (wikipedia.org)
  • Development will ensue normally and after many mitotic divisions, this single cell forms a blastocyst (an early stage embryo with about 100 cells) with an identical genome to the original organism (i.e. a clone). (wikipedia.org)
  • SCNT
  • The first study to review the long-term health outcomes of cloning, the authors found no evidence of late-onset, non-communicable diseases other than some minor examples of osteoarthritis and concluded "We could find no evidence, therefore, of a detrimental long-term effect of cloning by SCNT on the health of aged offspring among our cohort. (wikipedia.org)
  • For example, if a person with Parkinson's disease donated his or her somatic cells, the stem cells resulting from SCNT would have genes that contribute to Parkinson's disease. (wikipedia.org)
  • Another application of SCNT stem cell research is using the patient specific stem cell lines to generate tissues or even organs for transplant into the specific patient. (wikipedia.org)
  • Only a handful of the labs in the world are currently using SCNT techniques in human stem cell research. (wikipedia.org)
  • donors
  • In 2015, she and colleagues in Church's lab used CRISPR to eliminate from pig cells 62 genes so potentially dangerous their very existence nixed previous efforts to turn pigs into organ donors. (scientificamerican.com)
  • 2001
  • When the editors of Time screamed on the cover of their February 19, 2001 issue, "Human Cloning is Closer than You Think! (apologeticspress.org)
  • A purebred Hereford calf clone named Chloe was born in 2001 at Kansas State University's purebred research unit. (wikipedia.org)
  • In 2001, Brazil cloned their first heifer, Vitória. (wikipedia.org)
  • blastocyst
  • Presence of epidermal growth factor during in vitro maturation of pig oocytes and embryo culture can modulate blastocyst development after in vitro fertilization. (publish.csiro.au)
  • sperm
  • The egg is then artificially coaxed to divide and behave in a way similar to a standard embryo fertilised by a sperm. (newscientist.com)
  • Snuppy has since been used in the first known successful breeding between cloned canines, after his sperm was used to artificially inseminate two cloned females, which resulted in the birth of 10 puppies in 2008. (wikipedia.org)
  • Theriogenology
  • He was a professor of theriogenology and biotechnology at Seoul National University (dismissed on March 20, 2006) who became infamous for fabricating a series of experiments, which appeared in high-profile journals, in the field of stem cell research. (wikipedia.org)
  • Department of theriogenology and biotechnology at Seoul National University for cloning Snuppy was led by Woo Suk Hwang. (wikipedia.org)
  • Hwang's
  • Until Hwang's claim, it was generally agreed that creating a human stem cell by cloning was next to impossible due to the complexity of primates. (wikipedia.org)
  • The investigation found that, despite his fabrications in previous projects, Hwang's research related to Snuppy was accurate and Snuppy was a clone of the adult Afghan hound. (wikipedia.org)
  • nuclei
  • The chromosomes may not separate at one of the two anaphases (called restitutional meiosis), or the nuclei produced may fuse or one of the polar bodies may fuse with the egg cell at some stage during its maturation. (wikipedia.org)
  • 2016
  • In January 2016 the scientist at the Central Institute for Research on Buffaloes in Hisar, India announced that they had cloned a buffalo offspring "Cirb Gaurav" using cells of the ventral side of the tail of superior buffalo. (wikipedia.org)
  • maturation
  • This review summarises recent achievements both in the background technologies (maturation, activation, embryo culture) and the actual performance of the nuclear replacement. (publish.csiro.au)
  • humans
  • But if eGenesis is to succeed in making designer pigs, let alone paving the way for new and improved humans, Yang will need to fix the miscarriage problem. (scientificamerican.com)
  • It should allow us to study genetic disease without having to use humans as guinea pigs, or indeed, guinea pigs as humans. (newscientist.com)
  • The experiment was criticised by Robert Klitzman, director of Columbia University's Masters in Bioethics program, who cited that the process raised the question of if humans are "just a mass of cells and biological processes? (wikipedia.org)
  • viability
  • There's the challenge of CRISPR'ing an unprecedented number of genes without compromising the viability of the designer pigs and without introducing aberrant edits. (scientificamerican.com)
  • 1997
  • For example, in May and June 1997, I authored a series on "Cloning-Scientific and Biblical Ramifications. (apologeticspress.org)
  • Gene, the first cloned calf in the world was born in 1997 at the American Breeders Service facilities in Deforest, Wisconsin, United States. (wikipedia.org)
  • stem-cell lines
  • It was later found that photographs he published did not depict what was suggested and that most of the stem-cell lines he claimed to have created were not clones at all. (wikipedia.org)
  • The disease specific stem cell lines could then be studied in order to better understand the condition. (wikipedia.org)
  • year
  • The big conference table in the windowless, unadorned basement room is strewn with 8.5-ounce cans of "Wild Jujube Drink" and snacks that Yang brought back from her Lunar New Year visit to China, where she spent five days with her parents and visited eGenesis's pig colony. (scientificamerican.com)
  • Even with ESCs from fertilised embryos, it takes a year to get a fully characterised stem cell line," he told New Scientist . (newscientist.com)