Cloned human cell cloning clone cells. Medical search. Frequent questions

One cloning technology that has been developed for mammalian and human cells is somatic cell nuclear transfer (SCNT). (news-medical.net)
Cloning, or somatic cell nuclear transfer (SCNT), is the technique used to produce Dolly the sheep, the first animal to be produced as a genetic copy of another adult. (eurostemcell.org)
Indeed, if passed, Hatch/Feinstein/Kerry would explicitly legalize doing in humans the very cloning procedure -- somatic cell nuclear transfer (SCNT) -- that was used to make Dolly the sheep . (lifeissues.net)
체세포 핵 치환 (Somatic-cell nuclear transfer, SCNT)은 난자 의 핵 을 제거한 후에, 체세포 의 핵을 이식하여 복제 를 하는 기술을 말한다. (wikipedia.org)
Somatic-cell nuclear transfer, the technique by which Dolly was created, was first used 40 years ago in research with tadpoles and frogs. (who.int)
Scientists were initially interested in somatic-cell nuclear transfer as a means of determining whether genes remain functional even after most of them have been switched off as the cells in a developing organism assume their specialized functions as blood cells, muscle cells, and so forth. (who.int)

SCNT is a method of cloning mammalian cells that can be used to create personalized embryonic stem cells from an adult animal or human. (news-medical.net)
Embryonic stem cells are immortal, and have the potential to develop into any type of adult cell, even after months growing in culture dishes. (news-medical.net)
By transferring adult cell DNA into an embryonic stem cell, it is possible to create a line of immortal embryonic cells that are able to develop into any type of adult cell, genetically identical to the donor. (news-medical.net)
The cloning method is based on the fact that cytoplasmic factors in mature, metaphase II oocytes are able to reset the identity of a transplanted adult cell nucleus to an embryonic state. (news-medical.net)
In humans, a major roadblock in achieving successful SCNT leading to embryonic stem cells has been the fact that human SCNT embryos fail to progress beyond the eight-cell stage. (news-medical.net)
They derived several human embryonic stem cell lines from these cloned embryos whose DNA was an exact match to the adult cell that donated the DNA. (news-medical.net)
This was the first successful reprogramming of human somatic cells into embryonic stem cells using a cloning technique, SCNT. (news-medical.net)
Dermal fibroblasts were taken from a 35-year old male and a 75-year-old male and used to create embryonic stem cells. (news-medical.net)
The adult cell nuclei were transferred into metaphase-II stage human oocytes, producing a karyotypically normal diploid embryonic stem cell line from each of the adult male donor cells. (news-medical.net)
Although attempts have not yet been made to create a therapeutic transplant from embryonic stem cells, the methods have been developed to allow the creation of functional, mature cells using human cell cloning technology. (news-medical.net)
The heated debate in our society over reproductive cloning, as well as therapeutic cloning to obtain embryonic stem cells, has been fueled by misconceptions and hyperbole on both sides. (flfamily.org)
Instead, embryonic stem cells are isolated from the cloned blastocyst. (eurostemcell.org)
To date, no human embryonic stem cell lines have been derived using therapeutic cloning, so both these possibilities remain very much in the future. (eurostemcell.org)
of these embryonic stem cells left and the adult stem cells are just not as promising. (echeat.com)
It is always and in every case morally wrong to intentionally kill an innocent human being at any point in life, including the embryonic stage of development. (all.org)
There are those in the government and scientific community who say more money must be spent on human embryonic stem cell research because it holds the most promise for helping people with conditions such as Alzheimer's disease. (all.org)
Alzheimer's researcher Ned Potter said, however, that human embryonic stem cell research would not help the Alzheimer's patient at all. (all.org)
The injection or infusion of embryonic stem cells are not the ones needed. (all.org)
Contrary to the impression many people have, research involving human embryonic stem cells is not new. (all.org)
Yet, human embryonic stem cell research has thus far been unsuccessful in the quest to develop any therapeutic treatments. (all.org)
Therefore, it is speculated that those who support human embryonic stem cell research are clamoring loudly for taxpayer dollars because private companies know human embryonic stem cell research is neither worth their time nor their money. (all.org)
It is further speculated that those who support human embryonic stem cell research are also seeking human embryos for the purposes of human cloning. (all.org)
If you're armed with the facts, you can defend millions of embryonic human beings, and maybe even help celebrities and media figures learn the truth. (all.org)
The fact that the DNA of a fully differentiated (adult) cell could be stimulated to revert to a condition comparable to that of a newly fertilized egg and to repeat the process of embryonic development demonstrates that all the genes in differentiated cells retain their functional capacity, although only a few are active. (who.int)

2. Over the years, the international community has tried without success to build a consensus on an international convention against the reproductive cloning of human beings. (who.int)
3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)
7. The WHO Regional Committee for Africa is invited to review this document for information and guidance concerning reproductive cloning of human beings. (who.int)
3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)
Elaboration of an international convention against reproductive cloning of human beings has been under consideration in the United Nations since December 2001 when the subject was included in the agenda of the fifty- sixth session as a supplementary agenda item at the request of France and Germany. (who.int)

The therapeutic potential of cloned human cells has been demonstrated by another study using human oocytes to reprogram adult cells of a type 1 diabetic. (news-medical.net)
Since some therapeutic approaches in various human diseases are based on the manipulation of helper and suppressor functions, the question whether committed suppressor cells exist has important practical implications in medicine. (ox.ac.uk)
In therapeutic cloning, the blastocyst is not transferred to a womb. (eurostemcell.org)
Another long-term hope for therapeutic cloning is that it could be used to generate cells that are genetically identical to a patient. (eurostemcell.org)
5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)

Pro-cloning forces have been working hard to convince state governments to pass constitutional amendments enshrining a "right" to clone and to destroy embryos for research. (flfamily.org)
Some prohibit only cloning for reproductive purposes and allow the creation of cloned human embryos for research, whereas others prohibit the creation of cloned embryos for any purpose. (who.int)

This has led to a lot of interest in SCNT, which is best known as the method used to pioneer whole animal cloning technology, such as Dolly the sheep. (news-medical.net)
But SCNT can also be used to clone human cells for transplant or other therapies. (news-medical.net)
In 2013, scientists reported a successful SCNT procedure by modifying the protocol for specific human oocyte biology. (news-medical.net)
Another successful attempt at human SCNT was made using cells from two adult males. (news-medical.net)
Comment: Indeed, if passed, "total cloning bans" H.R. 534, H.R. 234, H.R. 916, and S. 245 would not ban anything either - not even the SCNT cloning technique that was used to make Dolly the sheep. (lifeissues.net)

To produce Dolly, the cloned blastocyst was transferred into the womb of a recipient ewe, where it developed and when born quickly became the world's most famous lamb. (eurostemcell.org)
Although many species produce clonal offspring in this fashion, Dolly, the lamb born in 1996 at a research institute in Scotland, was the first asexually produced mammalian clone. (who.int)

These stem cells are genetically matched to the donor organism, holding promise for studying genetic disease. (eurostemcell.org)
Reproductive cloning is performed with the express intent of creating another organism. (echeat.com)
A clone is an organism that is a genetic copy of an existing one. (who.int)
The science fiction definition of "clone" suggests that the cloned organism would be an exact genetic copy of another creature-human or beast-created in the laboratory by any of a number of means. (all.org)
There are differences-so much so that despite the "exact copy" claim, the cloned organism is actually unique genetically. (all.org)

To clone a human CTR (hCTR), a BIN-67 cDNA library was screened using a cDNA probe from a porcine renal CTR (pCTR) that we recently cloned. (jci.org)
Transfection of this cDNA into COS cells resulted in expression of receptors with high affinity for salmon CT (Kd = approximately 0.44 nM) and for human CT (Kd = approximately 5.4 nM). (jci.org)
The cloned cDNA encodes a putative peptide of 490 amino acids with seven potential transmembrane domains. (jci.org)
Complete cDNA cloning in human and partial cloning in Chinese hamster ovary cells. (nih.gov)

The mitochondrial DNA of the stem cells, however, matched the donor egg's mitochondrial DNA. (news-medical.net)
Paul Wagle, M.A., discusses his experience with a life-saving adult stem cell treatment, and the importance of promoting ethical approaches to medical research. (flfamily.org)
The rapidly emerging "regenerative" field of medicine is relying heavily on the use of ethically obtained stem cells. (flfamily.org)
What's All the Fuss About Stem Cells? (flfamily.org)
What are stem cells and why are they so fraught with both hope and controversy? (flfamily.org)
CLI's Vice President and Research Director, Dr. David Prentice, recently joined Molly Smith, host of From the Median, to explain the science, history, and politics of stem cells. (flfamily.org)
Professor Hwang Woo-suk was chairman of the World Stem Cell Hub, which opened this month, based in Seoul. (bbc.co.uk)
Dr Hwang, 52, gained worldwide fame after producing the world's first cloned human embryos and stem cells tailored to be used on individuals. (bbc.co.uk)
Human cloning science offers the possibility that stem cells harvested from cloned embryos could be used to treat diseases like Parkinson's, diabetes and heart disease. (bbc.co.uk)
Dr Hwang's breakthrough was seen as particularly important as the stem cells he created were a perfect match for the patient, which could mean treatments without the risk of the body rejecting them. (bbc.co.uk)
The professor said he was resigning from all public posts, including his chairmanship of the World Stem Cell Hub, which is designed to produce stem cell lines for disease research worldwide. (bbc.co.uk)
What is cloning, and what does it have to do with stem cell research? (eurostemcell.org)
This form of cloning is unrelated to stem cell research. (eurostemcell.org)
For example, stem cells could be generated using the nuclear transfer process described above, with the donor adult cell coming from a patient with diabetes or Alzheimer's. (eurostemcell.org)
The stem cells could be studied in the laboratory to help researchers understand what goes wrong in diseases like these. (eurostemcell.org)
It's given name is the "Human Cloning Ban and Stem Cell Research Protection Act of 2003," the stated purpose of which, supposedly, is to "prohibit human cloning and to protect important areas of medical research, including stem cell research. (lifeissues.net)
A stem cell is a type of cell found throughout the body of all human beings. (all.org)
Stem cells can reproduce themselves over a long period of time without changing. (all.org)
Obtaining stem cells from a human embryo is highly unethical. (all.org)
There is only one way to obtain stem cells from a developing human embryo, and it involves killing the embryo. (all.org)
Obtaining stem cells from fatty tissue, bone marrow, or the umbilical cord after the birth of a baby, on the other hand, may be done ethically. (all.org)
No harm comes to the person whose stem cells are obtained for research in such a fashion. (all.org)
On the other hand, research involving adult stem cells has not only been around for a long time, it has also been used successfully for decades! (all.org)
There are more than 70 diseases or conditions-including leukemia, immune system and other blood disorders, cancers, and autoimmune diseases-that respond well when adult stem cell therapy is used. (all.org)
While stem cell research and human cloning are complex topics, the facts are readily available. (all.org)

General Assembly the adoption of a declaration on human cloning by which Member States were called upon to prohibit all forms of human cloning inasmuch as they are incompatible with human dignity and the protection of human life. (who.int)

WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)
WHA50.37, which states "the use of cloning for the replication of human individuals is ethically unacceptable and contrary to human integrity and morality. (who.int)

After many divisions in culture, this single cell forms a blastocyst (an early stage embryo with about 100 cells) with almost identical DNA to the original donor who provided the adult cell - a genetic clone. (eurostemcell.org)

Human cloning is a reality, with human cloning experiments now being conducted-not by fictional wild-eyed rebels, but by credentialed experts working in some of the world's most respected institutions, some of which are publicly funded with tax dollars. (all.org)

Cloning of human cells is a technology that holds the potential to cure many diseases and provide a source of exactly matched transplant tissues and organs. (news-medical.net)
These cells have been sought after as potential therapies for diseases ranging from heart disease to Parkinson's to cancer. (news-medical.net)

There are no international laws governing the use of cells and embryos, but scientists said a tough regulatory climate - like that in force in the UK - could prevent such abuses or misunderstandings. (bbc.co.uk)
Scientists cloned another Jersey calf using the same "standard cell-culturing techniques as compared to the method most commonly u. (echeat.com)
1. Cloning is an umbrella term traditionally used by scientists to describe different processes for duplicating biological material. (who.int)

it will naturally not be long before we actively clone people as complete entities. (echeat.com)

more to this argument to quote Scripture that indicates Gods commandments that human beings venerate life. (echeat.com)
The use of the technique of nuclear transfer for reproduction of human beings is surrounded by strong ethical concerns and controversies and is considered a threat to human dignity. (who.int)

In Alzheimer's, it is the degeneration of the nerve cells that cause the problem because they lose their ability to connect with each other. (all.org)

In four pages the sociobiological aspects of cloning are examined in a consideration of Social Darwinism, disease replication, r. (echeat.com)
2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)

After being inserted into the egg, the adult cell nucleus is reprogrammed by the host cell. (eurostemcell.org)

In this procedure, the nucleus of an egg cell is removed and replaced by the nucleus of a cell from another adult. (eurostemcell.org)

Researchers have determined that several steps in the protocol were critical for human cellular reprogramming. (news-medical.net)
Cellular cloning refers to a process in which "copies of a cell ar. (echeat.com)
These molecules control several aspects of neural cell life including axonal growth, cellular migration, and cell death, and therefore, are of increasing interest in the field of spinal cord injury (SCI). (bvsalud.org)

Thus, the clone would be genetically identical to the nucleus donor only if the egg came from the same donor or from her maternal line. (who.int)
Beyond this scientific interest, the commercial concern in animal cloning focuses on replicating large numbers of genetically identical animals, especially those derived from a progenitor that has been modified genetically. (who.int)

A human ovarian small cell carcinoma line (BIN-67) expresses abundant calcitonin (CT) receptors (CTR) (143,000 per cell) that are coupled, to adenylate cyclase. (jci.org)

A human embryo is an innocent human being in his first stage of life. (all.org)

The nucleus of an adult somatic cell (such as a skin cell) is removed and transferred to an enucleated egg, which is then stimulated with electric current or chemicals to activate cell division. (who.int)
However, an animal created through this technique would not be a precise genetic copy of the source of its nuclear DNA because each clone derives a small amount of its DNA from the mitochondria of the egg (which lie outside the nucleus) rather than from the donor of cell nucleus. (who.int)

However, opponents argue that creating and experimenting with human embryos is unethical. (bbc.co.uk)

Those were spindle removal, donor cell fusion, and cytoplast activation. (news-medical.net)
The resulting cells were pluripotent and could be differentiated into insulin-producing beta cells to restore the function of the pancreas in the donor. (news-medical.net)
if it implants and the pregnancy goes to term, the resulting individual will carry the same nuclear genetic material as the donor of the adult somatic cell. (who.int)

Common myths about immoral clones and a world full of exact duplicates are refuted in this paper, which argues in favor of continu. (echeat.com)

This technique is surrounded by strong ethical concerns and is considered a threat to human dignity. (who.int)

The present report gives an overview of the terms and methods used in cloning and summarizes the debates in the General Assembly. (who.int)

Inhibiting these molecules has been shown to increase neuroprotection, enhance axonal regeneration, and facilitate the implementation of cell replacement therapies. (bvsalud.org)

Dr. Condic discusses the beginning of human life and the moral status of the human being. (flfamily.org)
In ten pages this paper discusses human cloning and how it can be misused in a consideration that includes past Nazi abuse and con. (echeat.com)

When the cloning process is used in this way, to produce a living duplicate of an existing animal, it is commonly called reproductive cloning. (eurostemcell.org)

Cloning, characterization, and expression of a human calcitonin receptor from an ovarian carcinoma cell line. (jci.org)
The structural differences may account for observed differences in binding affinity between the porcine renal and human ovarian CTRs. (jci.org)
Ovarian cancer cell heparan sulfate 6-O-sulfotransferases regulate an angiogenic program induced by heparin-binding epidermal growth factor (EGF)-like growth factor/EGF receptor signaling. (nih.gov)

General Assembly the following year,3 and the World Medical Association's Resolution on Cloning, endorsed in 1997, have confronted the issue but lack binding legal force. (who.int)

Another argument in favor of animal cloning is that which relates to products. (echeat.com)

The research conducted by his team requires large numbers of human eggs, which are difficult to obtain. (bbc.co.uk)
In other words, the author relates legislation that allows for human cloning to take place in a research realm, as long as no clon. (echeat.com)

The term applies not only to entire organisms but also to copies of molecules (such as DNA) and cells. (who.int)

In contrast to the ease of cloning and characterizing, at the molecular level, helper and cytotoxic T cells, suppressor T cells remain an enigma, and their existence as discrete entities is being increasingly challenged. (ox.ac.uk)

In an article that talks about technological advances in general, human cloning is discussed. (echeat.com)

While I have to agree with the author's concerns (we'll call him Kettle) about the use of waffling and fake science in the supposed cloning "bans" proposed by the Pots, if truth be told, there's enough concern to go around for both the Pots and the Kettles. (lifeissues.net)

Most natural cloning occurs in those species that produce their descendants asexually, that is, without combining the male and female genetic material. (who.int)

The term "clone", from the Greek word for twig, denotes a group of identical entities. (who.int)

It is secular science, in concert with international standards, agreed to by human embryologists from around the world, most of whom are not pro-life or even religious themselves. (all.org)

Retrieved on December 04, 2023 from https://www.news-medical.net/life-sciences/Cloning-Human-Cells.aspx. (news-medical.net)

Human bifunctional T cell clones regulate the activity of an autologous T cell clone. (ox.ac.uk)

How would you feel knowing that a human life was created only to be destroyed for your benefit? (flfamily.org)

Anatomy6

Organisms1

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment13

Phenomena and Processes19

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Somatic cell nuc6

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