Clone the monkeys clone humans. Medical search. Frequent questions

Researchers from the Chinese Academy of Sciences Institute of Neuroscience announced in a Jan. 24 article for the journal Cell that they produced two genetically-identical long-tailed macaque monkeys using a scientific technique known as somatic cell nuclear transfer (SCNT). (christian-heritage-news.com)
January 24 - Scientists in China report in the journal Cell the creation of the first monkey clones using somatic cell nuclear transfer, named Zhong Zhong and Hua Hua. (wikipedia.org)
The first cloned monkeys made with somatic cell nuclear transfer (SCNT) were born recently, according to Chinese scientists. (bioedge.org)
It became a hot topic in 1996 when Dolly the sheep was cloned via a process called somatic cell nuclear transfer. (archstl.org)
The researchers used somatic cell nuclear transfer, the same technique used to clone Dolly the sheep more than two decades ago, to clone the monkey and produce five cloned offspring. (inverse.com)
On November 27, 2017, the worldundefineds first somatic cloned monkey "Zhong" was born at the Institute of Neuroscience of the Chinese Academy of Sciences, the non-human primate platform of the. (informationisbeautifulawards.com)
Twenty years have passed since Dolly the sheep was born by cloning (somatic cell nuclear transfer, SCNT) but the results of non-human mammalian cloning are very poor, and cause animal diseases and huge biological losses. (sibi.org)
I believe that the reprogramming errors are not the only cause of these low rates of cloning: the mammalian SCNT fails with a very high frequency mainly due to the damage that the technique itself inflicts in the egg and the somatic nucleus, and the very few successful cases occur only when the damage is not significant. (sibi.org)
True cloning performed by nuclear transfer from an adult and differentiated somatic cell to a previously enucleated egg (somatic cell nuclear transfer, SCNT), gives rise to a new cell, the nuclovulo (nucleus+ovum), distinct from the zygote because the sperm is not involved in its creation, while both can develop as embryos and give rise to offspring. (sibi.org)

It took 127 eggs and 79 embryos to get these results, and it still required a fetus to work (Dolly was cloned from an adult). (engadget.com)
The MIT Technology Review published on Wednesday a news report about the first-known experiment to create genetically modified human embryos in the United States using a gene-editing tool called CRISPR. (cnn.com)
Previously, scientists in China were the first in the world to reveal attempts to modify genes in human embryos using CRISPR. (cnn.com)
Three separate papers were published in scientific journals describing various studies in China on gene editing in human embryos. (cnn.com)
It's not the first time anybody has CRISPR-ed human embryos. (cnn.com)
Scientists want to make cloned human embryos to get embryonic stem cells, which live inside early embryos and have the potential to cure a wide array of diseases. (irfi.org)
The Catholic Church has always held that stem-cell research and therapies are morally acceptable, as long as they don't involve the creation and destruction of human embryos. (archstl.org)
Mouse embryos will be implanted with human cells and then brought to term with a surrogate mother. (jstor.org)
Elsewhere on this site I describe my own conversations with a British scientist in the 1980s who was attempting then to clone human embryos - with some success. (globalchange.com)
A) a diagram of the cloning procedure using SCNT, B) the cloned embryos at different stages of development, and C) the five cloned monkeys. (inverse.com)
The efﬁciency of cloning, deﬁned as the proportion of transferred embryos that result in viable offspring, is approximately 2 to 3% for all species. (sibi.org)

In 1999 scientists managed to "clone" a rhesus macaque by splitting an early-stage macaque embryo into multiple parts, but that attempt only resulted in creating a couple of identical twins, and not true clones. (blastingnews.com)
This technique involves inserting DNA from one monkey into an enucleated egg of another to create an embryo. (bioedge.org)
For instance, he wonders-just an intellectual puzzle, he assures me, that he would never want to do-What would happen if scientists injected human stem cells into a monkey embryo? (discovermagazine.com)
But it is perhaps not auspicious to quote him for purposes of the scientific debates on human cloning, because Ramsey agreed with and supported the scientific myth of the "pre-embryo" 47 made famous by Jesuit Richard McCormick and frog embryologist Clifford Grobstein. (lifeissues.net)
Thus, while Ramsey agreed that there is a human being present immediately at fertilization, he did not agree that it was also a human embryo or a human person - the classic "pre-embryo" argument. (lifeissues.net)
The human embryo did not begin until after 14-days, thus the above quote from Saunders would not apply. (lifeissues.net)
Perhaps Ramsey would give other extraordinarily powerful arguments as to why human cloning is unethical, but he obviously would not be able to base it on his unscientific "pre-embryo" position. (lifeissues.net)
6. " ... any living human embryo has the inherent 'potential' to develop into a healthy baby . (lifeissues.net)
Originally the relevant philosophical term was "potency" (or inherent power or capacity conveyed by a specific nature) was used to apply to an already existing substance - such as a new living human embryo. (lifeissues.net)
In that sense, the human embryo would not be even a human being yet, much less a human person. (lifeissues.net)
Thus if by "potential" one means "potency" - i.e., that the early human embryo already exists with a human nature that is already there, and has its own inherent power or capacity (provided by that human nature) to simply grow bigger and bigger through all the usual developmental stages through birth, then such a statement stands as accurate - both scientifically and philosophically. (lifeissues.net)
That is, it would be acknowledging that the human embryo and the human " baby " are the same human being and human person throughout all of his/her development. (lifeissues.net)
On the other hand, if by "potential" one means that the human embryo is not a human being or human person yet , but might be later once it has been born (i.e., a "baby"), then that statement is both scientifically and philosophically incorrect. (lifeissues.net)
Otherwise, such a treaty would not recognize the inherent human nature of the early human embryo or fetus until after birth , and thus cloning them and using them for research - both "therapeutic" and "reproductive" -- would not be banned, and women undergoing "infertility treatments" could surely be put in danger. (lifeissues.net)
Again, Saunders is referring to SCNT as "THE" cloning procedure, when there are many other ways to clone a human being as well, and he is scientifically mis-defining the product of SCNT (i.e., the cloned human embryo). (lifeissues.net)
In 2007, a research team led by Mitalipov announced they created t he first cloned monkey embryo and extracted stem cells from it. (cnn.com)
it cannot work properly, and so the cloned embryo grows in an uncontrolled way. (irfi.org)
Dr John Parrington, a cloning expert at University College London, pointed out that more than one gene behaved in a way that might cause problems in a growing cloned human embryo. (irfi.org)
On April 11, 2003, Washington Post Staff Writer, Rick Weiss, reported 'New research suggests that it may be a lot harder to clone people than to clone other animals, an unexpected scientific twist that could influence the escalating congressional debate over human cloning and embryo research. (irfi.org)
In the light of this information, Congress could settle for less stringent restrictions on embryo cloning studies, which scientists favor. (irfi.org)
But opponents of human embryo research were afraid that the new research not only identifies previously unrecognized hurdles to human cloning, but also points the way to overcoming those hurdles. (irfi.org)
2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
That's why Father Pacholczyk, director of education at the National Catholic Bioethics Center in Philadelphia, said that the efforts to help people understand the immorality of embryo reserch, including human cloning, must focus on humanizing the issue and appreciating our own embryonic origins, not just on the desired results of embryonic or other types of stem-cell research. (archstl.org)
The National Institutes of Health defines a human embryo as "the developing organism from the time of fertilization until the end of the eighth week of gestation. (archstl.org)
Some people are very uneasy about creating a human embryo and then dismembering it, however early the stage, to obtain embryonic stem cells from which useful tissues might be grown. (globalchange.com)
The original monkey was altered as an embryo by knocking out its BMAL1 gene, which is associated with regulating sleep-wake patterns, and the five newborns produced with SCNT all have identical genomes that also lack the BMAL1 gene. (inverse.com)
My 400-page doctoral dissertation was titled, A Philosophical and Scientific Analysis of the Nature of the Early Human Embryo (Georgetown University 1991). (lifeissues.net)
Among the factors thought to contribute to the greater success in cloning cattle are the relatively late embryonic genome activation speciﬁc for this species [16 -18] and the optimization of reproductive technologies, such as in vitro embryo production and embryo transfer, brought about by the cattle industry [19]. (sibi.org)

SHANGHAI (BP) -- The first-ever primates cloned through a technique that produced Dolly the sheep have been cited by Christian bioethicists as a potentially valuable development in animal research. (christian-heritage-news.com)
According to Cell.com, previously it was assumed that this cloning technique would not work for primates, yet the Chinese biologists managed to refine the tech to make it suitable for cloning monkeys. (blastingnews.com)
We describe the first reported transmission to a human of simian foamy virus (SFV) from a free-ranging population of nonhuman primates in Asia. (cdc.gov)
Nonhuman primates, by virtue of their genetic, physiologic, and sometimes social similarities to humans, are particularly likely sources of infectious agents that pose a threat to humans ( 1 , 2 ). (cdc.gov)
scientists now theorize that SIVs were transmitted from primates to humans on several occasions ( 3 , 4 ). (cdc.gov)
Serologic studies have demonstrated evidence of primate-to-human transmission of simian retrovirus (SRV), a retrovirus enzootic among Old World monkeys, in laboratory workers exposed to captive primates ( 10 ). (cdc.gov)
SFV is present in highest concentrations in the saliva of infected laboratory macaques ( Macaca mulatta and M . fascicularis ) and African green monkeys ( Cercopithecus aethiops ), which suggests that bites, scratches, and mucosal splashes with saliva from primates are likely mechanisms of transmission ( 25 - 27 ). (cdc.gov)
Because SFV is not known to occur naturally in humans, detecting serologic or molecular evidence, or both, of infection in a human, along with a history of close contact with primates, constitutes strong evidence for primate-to-human transmission, i.e., a marker for cross-species transmission ( 28 ). (cdc.gov)
You can't say, taking this information in isolation, that it's easier to clone primates and humans,' he said. (irfi.org)
The scientists said they suspect that similar roadblocks exist for all primates -- the evolutionary grouping that includes monkeys and humans. (irfi.org)
All involve experiments on non-human primates, but the list of papers under investigation does not include the monkey paper from Hauser's lab that we've discussed most extensively here: W. Tecumseh Fitch and Marc D. Hauser, " Computational Constraints on Syntactic Processing in a Nonhuman Primate ", Science 303(5656):377-380, 16 January 2004. (upenn.edu)
Recently, two baby monkeys were cloned-the first time primates have been successfully duplicated. (jstor.org)
As Amber Tong reported for Endpoints News at the time, the challenges of cloning primates made this achievement a momentous one. (inverse.com)
Adding on top of that the successful cloning of primates with CRISPR-mediated gene deletions, the researchers have gone to great lengths to study the biological mechanisms for genetic diseases. (inverse.com)
In a meeting in Washington (3 December 2001) the researcher Tanja Dominko presented the results of monkey cloning (Macacus rhesus) when she worked at the Regional Center of Research in Primates of Beaverton, Oregon (USA). (sibi.org)
Viral isolates have since been obtained from several species of nonhuman primates including African green monkeys (2), sooty mangabeys (3), pig-tailed macaques (4), and stump-tailed macaques (5). (cdc.gov)
Also, SIV is distinct from simian T-cell lymphotropic virus type I (STLY-I) which shares extensive genomic sequences with human T-lymphotropic virus type I and is associated with T-cell lymphomas in nonhuman primates (12). (cdc.gov)

Ever since cloning produced Dolly the sheep , scientists have copied a slew of mammals ranging from dogs to ponies. (engadget.com)
Chinese researchers have successfully cloned a macaque monkey fetus twice, producing sister monkeys Hua Hua and Zhong Zhong using the same basic method used to create Dolly. (engadget.com)
Macaques successfully cloned in China using similar technique which gave birth to Dolly the sheep. (blastingnews.com)
Chinese scientists have cloned monkeys using the same technique that produced Dolly the sheep. (asianage.com)
He stayed on to earn his Ph.D. in molecular biology at Cambridge, training under the legendary geneticist John Gurdon, whose breakthroughs in the 1950s and 1960s were key to the experiments performed by Ian Wilmut, a Gurdon student who cloned Dolly the sheep in 1997. (discovermagazine.com)
Even the world's most famous sheep clone, Dolly, who died recently suffered from problems linked to this gene. (irfi.org)
It seems that a little knowledge is a dangerous thing, and the authors have allowed themselves to over-interpretate their interesting results,' said Professor Ian Wilmut of the Roslin Institute, in Edinburgh, leader of the team, which cloned Dolly the sheep. (irfi.org)
Let's wind back the clock: these scientists had already carried out successful human nuclear transfer into an unfertilised egg before Dolly the sheep clone had been made. (globalchange.com)
But even they omitted to tell us anything until Dolly was seven months old, well over a year after the cloning technique was successfully carried out and a good two to three years perhaps after they began their secretive work. (globalchange.com)

This Anti-Dopamine Transporter Antibody, N-terminus, clone DAT-Nt is validated for use in IC, IH, WB for the detection of Dopamine Transporter. (sigmaaldrich.com)
CD59 antibody LS-C44071 is an RPE-conjugated mouse monoclonal antibody to human CD59. (lsbio.com)
Vimentin antibody LS-C358406 is an unconjugated rabbit polyclonal antibody to Vimentin (N-Terminus) from human. (lsbio.com)
The 5H9 monoclonal antibody specifically binds to the human form of the leukocyte common antigen (LCA), CD45RA. (bdbiosciences.com)
If these findings are generalized in the newly funded work, it should be possible using molecular cloning approaches to isolate unique combinations of rhesus and human antibody precursors and HIV envelopes that bind them with high affinity. (pennmedicine.org)
Antibody Response of Monkeys to Invasion Plasmid Antigen D after Infection with Shigella spp. (ku.edu)
To overcome the lack of specificity for individual antigens in the water-extract enzyme-linked immunosorbent assay (ELISA), the ipaD gene from S. flexneri has been cloned, expressed to a high level, and purified for use in a new ELISA for the determination of the levels of antibody against IpaD in monkeys and humans challenged with shigellae. (ku.edu)
The IpaD ELISA for serum immunoglobulins G and A correlated well with the water-extract ELISA in that monkeys infected with S. flexneri or S. sonnei responded with high serum antibody titers in both assays. (ku.edu)
The MC-813-70 antibody reacts with stage-specific embryonic antigen-4 (SSEA-4), a glycolipid carbohydrate antigen expressed on the surface of human embryonal carcinoma (EC), embryonic germ (EG), undifferentiated embryonic stem (ES) and induced pluripotent stem (iPS) cells, a subset of mesenchymal stem cells, and rhesus monkey ES cell lines. (stemcell.com)

Chinese scientists have successfully cloned two monkeys, breaking a key barrier to cloning humans. (hancockwildlife.org)
The cloning method used by the Chinese scientists "should not become a test case for the perfection of human cloning techniques," said Raymond Johnson, a Pennsylvania pastor who received a financial award from Trinity International University last year to help him study the relationship between Christianity and science. (christian-heritage-news.com)
As such, monkey cloning may be limited to medical research, where having more than one monkey with the same genes could help scientists compare the results of treatments or test under specific conditions. (engadget.com)
A group of scientists from the Chinese Academy of Sciences have reported on their success in primate cloning. (blastingnews.com)
The scientists added matrix RNA and trichostatin A to the cloned genome in order to significantly reduce the probability the animals they cloned would die. (blastingnews.com)
In the middle of the year 2001 a group of scientists said cloning humans might be easier than cloning animals. (irfi.org)
Many scientists were dismayed and scientists involved in animal cloning warned of the many practical problems in cloning. (irfi.org)
The new work by scientists in Pittsburgh provides an explanation for why hundreds of attempts to clone monkeys have all failed despite successes in several other mammals. (irfi.org)
The newly discovered obstacle makes it more likely than ever that rogue scientists' recent claims to have created cloned babies were fraud. (irfi.org)
1. Cloning is an umbrella term traditionally used by scientists to describe different processes for duplicating biological material. (who.int)
Five clones of a gene-edited long-tailed macaque with several symptoms of genetic disease have been successfully bred, announced a team of scientists in Shanghai this week. (inverse.com)
The original monkey had been altered with CRISPR/Cas9 gene editing technology to give its clones a disrupted circadian rhythm so that scientists can learn how to treat humans with related disorders. (inverse.com)

Previously, Mitalipov and his colleagues reported the first success in cloning human stem cells in 2013, successfully reprogramming human skin cells back to their embryonic state. (cnn.com)
Exactly one year ago, the same researchers announced that they'd successfully cloned two macaques , named Hua Hua and Zhong Zhong. (inverse.com)
For one thing, the team used the cloned monkeys' resulting psychiatric disorders - including "behaviors resembling anxiety, depression, and schizophrenia" - as signs that they had performed the experiment successfully. (inverse.com)
Strains of SIV have been successfully cultured in human lymphocyte cell lines (e.g. (cdc.gov)

Although Zhong Zhong and Hua Hua, two genetically identical long-tailed macaques, are not the world's first cloned monkeys, they are the first to be born using SCNT. (bioedge.org)
The first successful SCNT monkey clones immediately sparked interest in in the dream of human cloning. (bioedge.org)

The transmission of an exogenous retrovirus, SFV, from macaques ( Macaca fascicularis ) to a human at a monkey temple in Bali, Indonesia, was investigated with molecular and serologic techniques. (cdc.gov)
Cloning and sequencing of PCR products confirmed the virus's close phylogenetic relationship to SFV isolated from macaques at the same temple. (cdc.gov)

A decade later, cloning came to the forefront in Missouri with the narrow passage of Amendment 2, a ballot initiative in 2006 that constitutionally protects embryonic stem-cell research and human cloning. (archstl.org)
Judging by the successful growth of the combined human-cow clone creation it appears that cow mitochondria may well be compatible with human embryonic development. (globalchange.com)
they might feel more comfortable with a hybrid solution, if it were shown that the embryonic cow-human stem cells were viable as tissue producers but not capable of becoming a baby. (globalchange.com)
So when I was recently contacted by an earnest and amiable member of a local school board who was concerned about the questionable manner in which the issue of "stem cell" research - both human embryonic and adult - was presented to the high school students in his district in a currently-used science textbook, I agreed to evaluate that section in the text for him. (lifeissues.net)
In my opinion there is no question but that the scientific information on stem cell research included in this science text book being used in Illinois schools incorporates some inaccurate scientific facts, and seems to be very partial to the use of human embryonic "stem cell" research. (lifeissues.net)

The cloning project was supported by the Chinese government, which promised further assistance in upcoming studies of primate cloning. (blastingnews.com)
It will unquestionably spark debate, however, over ethical aspects of potentially cloning yet another primate species, Homo Sapiens . (blastingnews.com)
There is now no barrier for cloning primate species, thus cloning humans is closer to reality. (bioedge.org)
As a result, concern is increasing that other infectious agents enzootic in primate populations may endanger humans ( 5 ). (cdc.gov)
The observed frequency of CD45RA positive lymphocytes is higher in the non-human primate compared to what is seen with normal human donor lymphocytes. (bdbiosciences.com)
In rhesus monkeys and other susceptible nonhuman primate species (e.g. pig-tailed macaque, crab-eating macaque), SIV infection leads to a chronic wasting disease syndrome with depletion of CD4 (T4) lymphocytes and lymphadenopathy. (cdc.gov)
HuT 78, HT, CEMx174) and in primary human and nonhuman primate peripheral blood leukocyte cultures (13). (cdc.gov)
For other human tumour virus- primate species are related to the hu- tween data in humans and in experi- es, the use of humanized severe man tumour viruses, the incidence of mental animals is not obvious. (who.int)

Named Zhong Zhong and Hua Hua , the two baby monkeys are aged eight and six weeks respectively. (blastingnews.com)

The world's first human clone of an adult has now been made, by an American biotechnology company in Massachusetts, Advanced Cell Technology. (globalchange.com)

Since the term "born" has been used as an essential part of the definition of " reproductive cloning " used by Weissman, the National Academy of Sciences, etc., then it is critical to use the accurate term with the proper meaning. (lifeissues.net)
2. Over the years, the international community has tried without success to build a consensus on an international convention against the reproductive cloning of human beings. (who.int)
3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)
7. The WHO Regional Committee for Africa is invited to review this document for information and guidance concerning reproductive cloning of human beings. (who.int)
3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)
5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
Human cloning ought to be banned, both reproductive cloning and so-called therapeutic cloning-or as Stanford University recently referred to it, "human nuclear transplantation. (probe.org)

In the proposed new work, Shaw and his team will seek to induce broadly neutralizing antibodies in rhesus monkeys via laboratory-created simian - human immunodeficiency viruses. (pennmedicine.org)
It addressed a major problem with SHIVs: the only HIV envelopes that would allow SHIVs to infect rhesus monkeys were artificially adapted to bind to the rhesus CD4 molecule, the primary receptor for the virus. (pennmedicine.org)
To surmount this problem, the Shaw team found that changing a single amino acid in what is called the "CD4 binding pocket"-out of about 850 that comprise the viral envelope-led to a much greater ability of SHIVs to infect rhesus monkeys, while at the same time retaining the basic features of the normal HIV envelope and its interaction with the human immune system. (pennmedicine.org)
The seroprevalence of SIV among rhesus monkeys in captive colonies (whether from natural infections or interspecies transmission) appears to be low (i.e., 0-1%) (6). (cdc.gov)

Immunolocalization of DAT on paraformaldehyde fixed frozen sections of human brain using MAB369 shows dense punctate staining throughout the caudate, putamen and accumbens (Miller, 1997). (sigmaaldrich.com)
WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)
Note: Please read The Little Lamb That Made a Monkey of Us All for the author's comments on the news of a successful lamb cloning (March 7, 1997). (probe.org)

From Steve Lefemine, Christians for Personhood : 'Eugenics and Planned Parenthood - Margaret Sanger' Forgotten History https://m.youtube.com/watch?v=OP7ZzV4Z338 'The term eugenics is basically a set of beliefs and practices that aim to improve the genetic quality of a human population, historically by excluding people and groups judged to be inferior and promoting those judged to be superior. (christian-heritage-news.com)
In theory, this makes human cloning more realistic given the genetic similarities between monkeys and our own species. (engadget.com)
Dr Mu-ming Poo, co-author of the research and director of the Chinese Academy of Sciences' Institute of Neuroscience, says that a population of genetically identical monkeys will be very useful for genetic research and drug development. (bioedge.org)
For example many clones die early or they are born with genetic deformities, and develop terminal illnesses such as cancer. (irfi.org)
A clone is an organism that is a genetic copy of an existing one. (who.int)
Without the interference of genetic background, a much smaller number of cloned monkeys carrying disease phenotypes may be sufficient for pre-clinical tests of the efficacy of therapeutics. (inverse.com)
Eve was delivered by Caesarian section from her twin sister (the woman who donated the nuclear genetic material from which she was cloned also served as the surrogate mother). (probe.org)
The human bone morphogenet ic protein (rhBMP) developed by genetic engineering, was isolated by Urist, in 1965, and it is considered a substance capable of inducing differentiation of mesenchymal stem cells into osteoblasts, the cells that are responsible for the synthesis of bone matrix. (bvsalud.org)

But they warned that two monkeys engineered by Chinese researchers must not become a step toward cloning humans. (christian-heritage-news.com)
The researchers also say finding that the gene works in a different way in humans from animals such as rats and mice has raised questions about large areas of medical research. (irfi.org)
Japanese researchers are creating a human-animal hybrid. (jstor.org)
The researchers are undeterred, as the benefits of the cloned monkeys could be significant for drug research. (inverse.com)
In an effort to overcome these envelope-based obstacles, the NIAID grant will allow the researchers, for the first time, to model the development of broadly neutralizing antibodies in SHIV-infected rhesus macaque monkeys. (pennmedicine.org)
Two other independent researchers, Severino Antinori (an Italian working in an undisclosed Muslim country) and Panos Zavos (from Lexington, Kentucky) have also been hinting at human cloning success and suggesting that a birth will be announced soon. (probe.org)
This incredibly high 50% success rate for human cloning leaves most researchers believing that either this isn't really a clone or they simply aren't revealing all the other failures. (probe.org)

The clinical course of this infection in monkeys, like that of AIDS in humans, is complicated by various opportunistic infections (7). (cdc.gov)

This mechanism of transmission contrasts with that of the two subspecies of African trypanosomes that cause human disease, Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense , which are transmitted via the saliva of their vectors, and with the mechanism by which the nonpathogenic trypanosome found in the Americas, Trypanosoma rangeli , is transmitted to its mammalian hosts. (medscape.com)

The resulting human form of the virus, HTLV, is the etiologic agent of 2 human diseases, adult T-cell leukemia and tropical spastic paresis ( 9 ). (cdc.gov)
Animal models for human tumour mental animals is not easy to answer does induce adult T-cell leukaemia/ viruses that make use of animal virus- for these agents, because cancer bi- lymphoma (ATLL), albeit in monkeys es are scarce. (who.int)

Disorder of circadian rhythm could lead to many human diseases, including sleep disorders, diabetic mellitus, cancer, and neurodegenerative diseases, our BMAL1-knock out monkeys thus could be used to study the disease pathogenesis as well as therapeutic treatments" says Hung-Chun Chang, senior author on both papers and a researcher at the Chinese Academy of Sciences Institute of Neuroscience, said in a statement . (inverse.com)

But in many animals other than humans, one of these genes is turned off. (irfi.org)
Technically 1% of the human clone genes would have belonged to the cow - the mitochondria genes. (globalchange.com)
For a start it raises the biggest question of all: how many human genes does a cow or monkey have to gain before we give it human rights? (globalchange.com)
Monkeys and humans have 97% of genes in common so if the right 1.6% were transferred from a human to a monkey we could land up with a monkey more human than animal. (globalchange.com)
And for the theologians another question: how many human genes does an animal have to have to need salvation? (globalchange.com)

The following ASCL4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). (genscript.com)

ORF sequences can be delivered in our standard vector, pcDNA3.1 + /C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. (genscript.com)
Expression of SSEA-4 is down-regulated following differentiation of human EC, ES, and iPS cells. (stemcell.com)
A 31 KDa protein was detected in chinese hamster ovary cells and in monkey kidney COS7 cells transfected with an expression vector containing the entire coding region of TEF cDNA. (cdc.gov)
These in vitro, and their expression in these human tumour virus. (who.int)

This clone also crossreacts with CD45RA expressed by peripheral blood lymphocytes, monocytes and some granulocytes from rhesus macaque, baboon, and cynomolgus monkeys. (bdbiosciences.com)

told Baptist Press, "even a quiet inference fortified by this experiment that human life is merely the result of cellular manipulation brings our culture ever closer to the slippery slope of crucial ethical and eugenic dilemmas. (christian-heritage-news.com)
The use of the technique of nuclear transfer for reproduction of human beings is surrounded by strong ethical concerns and controversies and is considered a threat to human dignity. (who.int)
This technique is surrounded by strong ethical concerns and is considered a threat to human dignity. (who.int)
Creating human organs in chimaera pigs: an ethical source of immunocompatible organs? (jstor.org)

He is the co-author of the book The Natural Limits to Biological Change , served as general editor of Creation, Evolution and Modern Science , co-author of Basic Questions on Genetics, Stem Cell Research and Cloning (The BioBasics Series) , and has published numerous journal articles. (probe.org)

Can Humans Be Cloned Like Sheep? (probe.org)

1991. Physiologically based pharmacokinetic modeling with dichloromethane, its metabolite, carbon monoxide, and blood carboxyhemoglobin in rats and humans. (cdc.gov)

Simian T-cell lymphotropic viruses, enzootic in both Asian and African Old World monkeys and apes, may have repeatedly crossed the species barrier ( 7 , 8 ). (cdc.gov)
The development of the human blood-CSF-brain barrier. (cdc.gov)

The psychological effects of the gene editing on the monkeys has, unsurprisingly, raised concerns among ethicists. (inverse.com)
In the paper, they explain that the ability to produce gene-edited clones will help them study diseases related to disrupted circadian rhythm , including Alzheimer's disease, depression, and other sleep problems. (inverse.com)
Bioethicist Carolyn Neuhaus from The Hastings Center told Gizmodo that the research raises a lot of questions, including the fundamental concern that this gene deletion might not actually produce the same effects in humans as it did in the monkeys. (inverse.com)

They were optimistic based on the research carried out into human genetics. (irfi.org)
The findings are published in the journal Human Molecular Genetics, but have been criticized in Britain. (irfi.org)
Marguerite Brickman has a B.A. in genetics from Columbia College, and a Ph.D. in genetics (not specifically "human genetics"), also from the University of California at Berkeley. (lifeissues.net)

Simian immunodeficiency virus (SIV) belongs to the family Retroviridae (subfamily Lentivirinae) and is closely related to human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2), the etiologic agents of acquired immunodeficiency syndrome (AIDS). (cdc.gov)

The family of SIV is 1 of 4 primateborne retroviruses known to infect humans ( 6 ). (cdc.gov)
For this reason, the infect humans, this virus can infect cordance between humans and ex- question about tumour site concor- several other species - including perimental animals. (who.int)

An Italian fertility doctor, Dr. Severino Antinori announced his intention to clone humans, so that he can help infertile couples to have children. (irfi.org)

Other recent studies verified the presence of PAPP-A mRNA in granulosa cells of humans, monkeys, cattle, mice, and pigs. (bioone.org)
Even then, many of the clones which survive to birth develop complications in their first months of life, as high as 10% in cattle. (probe.org)
However, in cattle, average cloning efﬁciency is higher than in other species, ranging from 5 to 20% [10 -15]. (sibi.org)

Can Human beings be Cloned? (irfi.org)
Materialism says that humans are only physical beings, which means there is no possibility of an immaterial mind or a soul. (probe.org)

The organism T cruzi and infection in humans were first described in 1909 by the Brazilian physician Carlos R. J. Chagas. (medscape.com)

The investigators expect such antibodies to occur more commonly in the monkeys than they do in human HIV infection and at an accelerated pace. (pennmedicine.org)

I think it's going to be possible to both engineer the viruses out of pigs and then clone the animals, so that you get the same ones again and again. (medscape.com)

Antibodies to SFV were detected by Western blotting of serum from 1 of 82 humans tested. (cdc.gov)
The research is premised on the human body's capacity, in rare individuals, to produce broadly neutralizing antibodies against HIV in the course of natural infection, and the hypothesis that SHIV infection of monkeys could do the same. (pennmedicine.org)
Despite decades of research, there are still no HIV vaccines for humans that can induce the body to make the broadly neutralizing antibodies viewed as capable of conferring protective immunity against the virus. (pennmedicine.org)
The basis for this speculation is preliminary data by the Penn team that showed that HIV envelopes that in humans elicited broadly neutralizing antibodies did the same in monkeys. (pennmedicine.org)
SHIVs, which contain HIV envelopes from humans that elicited broadly neutralizing antibodies or were found to bind to precursors of these antibodies, will be used to infect monkeys. (pennmedicine.org)

7. "[footnote 16]: The cloning procedure supplies the oocyte with a complete set of chromosomes, all of which are contained in the nucleus which is transferred into the denucleated oocyte. (lifeissues.net)

There's also the question of what happens with those clones that do survive into adulthood -- they may face pressure to live up to the original. (engadget.com)

We are a global provider of human and animal biospecimens: including frozen & FFPE tissue, DNA, RNA, total proteins, blood products and primary cells. (amsbio.com)

Arenaviruses are single-stranded ribonucleic acid (RNA) viruses that cause chronic asymptomatic infections in rodents and zoonotically acquired disease in humans through rodent excreta, especially urine. (medscape.com)
Plus, if that human being went out and sneezed, coughed, excreted, and sweated, then maybe those viruses would be dumped into a home environment or public environments and we would inadvertently cause epidemics. (medscape.com)
Among the biological agents re- because species specificity limits the causes lymphoproliferative diseas- viewed in Volume 100B of the IARC feasibility of this approach for most of es in New World monkeys and in Monographs (IARC, 2012) are sever- these viruses. (who.int)
One exception is hu- humanized SCID mice, the use of al oncogenic viruses that are strictly man T-cell lymphotropic virus type 1 surrogate hosts has not proven very species-specific, causing cancer in (HTLV-1): in addition to its ability to useful for defining tumour site con- humans only. (who.int)
Moreover, The use of animals as surrogate rine host, can provide a platform for animal models for tumour viruses in hosts for the study of human tu- in vivo infection. (who.int)

Cd has been classified by the International Agency for Research on Cancer (IARC) as a human carcinogen. (cdc.gov)

Limited studies of wild-caught African green monkeys from Central Africa indicate a seroprevalence of approximately 30%-50%, apparently without associated immunodeficiency disease. (cdc.gov)
In this combined immunodeficiency (SCID) cancer is low in these species (as it chapter, some aspects of this issue mice, in which the human target is in humans), which renders cancer are discussed. (who.int)

I knew and had great respect for the famous Protestant theologian and bioethicist Paul Ramsey, and used much of his work concerning the use of human subjects in research in my own. (lifeissues.net)
His research focuses on the evolutionary roots of the human mind. (upenn.edu)
The research, however, is a long way from producing human organs, if indeed it ever does. (jstor.org)
If this research is pursued, and especially if a working model of animal-human organs is developed, many animals will die. (jstor.org)
And in fact, Mu-ming Poo, Ph.D., a senior investigator at the Academy's Institute of Neuroscience and one of the authors on the papers, says the research could actually result in a net decrease to monkey suffering in scientific labs. (inverse.com)
This line of research will help to reduce the amount of macaque monkeys currently used in biomedical research around the world," he told The Independent . (inverse.com)
Not only that, but poor Eve, who I believe is a full human being with a soul, will be a research subject all her life, however long that is. (probe.org)

Anatomy30

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